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| 1 | 气候与土地利用变化对流域水资源的影响--以美国北卡罗莱纳州Trent流域为例显示文摘分布式水文模型PRMS可为气候与土地利用变化对流域水资源影响的研究提供技术和理论支撑。对Trent流域产流过程采用PRMS模型进行模拟检验,结果表明,Nash模型确定性系数达到0.8以上。水文响应单元(HRU)划分尺度减小,可以有效地提高PRMS模拟精度达7%左右,划分尺度缩小到71个HRU时,模拟精度不再提高。流域蒸散量和产流量对土地利用和气候变化的敏感程度为:降水量变化〉城市土地利用变化〉气温变化〉农作物和草地(林地)变化;土地利用变化和气候变化对流域产流量的影响大于蒸散量。利用PRMS模型预测Trent流域在未来气候和土地利用同时变化条件下,多年平均蒸散量将增加5.64~201.29mm,产流量有可能增加160mm左右或减少180mm左右。 | 王云琦 齐实 孙阁 Steve G McNulty | 2011 | 水科学进展2011，22，1： | 32 |
| 2 | Cardiotrophin 1 stimulates beneficial myogenic and vascular remodeling of the heart显示文摘出生后的心通过 hypertrophic 生长适应应力和超载,可能病理学或有益的一个过程(生理的肥大) 。生理的肥大改进心脏的性能在健康并且 diseased 个人,然而,宣传这有利改编的机制仍然保持糟糕定义。我们识别 cytokine cardiotrophin (CT1 ) 1 作为能够包括导致的导出 cardiomyocyte 的 angiogenic 信号的心肌层,和刺激的短暂、可逆的肥大概括心的生理的生长的特色的一个因素增加了由脉管形成。CT1 的能力从 caspase 激活的调停 CK2 的制止发源导致生理的肥大,阻止到无限制的病理学的生长的转变。外长的 CT1 蛋白质交货稀释了病理并且在正确的心失败的一个严格的模型恢复了可收缩的功能,建议为这难处理的心脏病的一种新奇处理选择。 | Mohammad Abdul-Ghani Colin Suen Baohua Jiang Yupu Deng Jonathan J Weldrick Charis Putinski Steve Brunette Pasan Femando Tom T Lee Peter Flynn Frans H H Leenen Patrick G Burgon Duncan J Stewar Lynn A Megeney | 2017 | Cell Research2017，27，10： | 8 |
| 3 | Probiotic metabolites from Bacillus coagulans GanedenBC30^(TM) support maturation of antigen-presenting cells in vitro显示文摘AIM:To study the effects of probiotic metabolites on maturation stage of antigen-presenting immune cells.METHODS:Ganeden Bacillus coagulans 30(GBC30) bacterial cultures in log phase were used to isolate the secreted metabolite(MET) fraction.A second fraction was made to generate a crude cell-wall-enriched fraction,by centrifugation and lysis,followed by washing.A preparation of MET was subjected to size exclusion centrifugation,generating three fractions:< 3 kDa,3-30 kDa,and 30-200 kDa and activities were tested in comparison to crude MET and cell wall in primary cultures of human peripheral blood mononuclear cell(PBMC) as a source of antigen-presenting mononuclear phagocytes.The maturation status of mononuclear phagocytes was evaluated by staining with monoclonal antibodies towards CD14,CD16,CD80 and CD86 and analyzed by flow cytometry.RESULTS:Treatment of PBMC with MET supported maturation of mononuclear phagocytes toward both macrophage and dendritic cell phenotypes.The biological activity unique to the metabolites included a reduction of CD14+ CD16+ pro-inflammatory cells,and this property was associated with the high molecular weight metabolite fraction.Changes were also seen for the dendritic cell maturation markers CD80 and CD86.On CD14dim cells,an increase in both CD80 and CD86 expression was seen,in contrast to a selective increase in CD86 expression on CD14bright cells.The co-expression of CD80 and CD86 indicates effective antigen presentation to T cells and support of T helper cell differentiation.The selective expression of CD86 in the absence of CD80 points to a role in generating T regulatory cells.CONCLUSION:The data show that a primary mechanism of action of GBC30 metabolites involves support of more mature phenotypes of antigen-presenting cells,important for immunological decision-making. | Kathleen F Benson Kimberlee A Redman Steve G Carter David Keller Sean Farmer John R Endres Gitte S Jensen | 2012 | World Journal of Gastroenterology2012，18，16： | 8 |
| 4 | Air quality monitoring using mobile microscopy and machine learning显示文摘Rapid,accurate and high-throughput sizing and quantification of particulate matter(PM)in air is crucial for monitoring and improving air quality.In fact,particles in air with a diameter of≤2.5μm have been classified as carcinogenic by the World Health Organization.Here we present a field-portable cost-effective platform for high-throughput quantification of particulate matter using computational lens-free microscopy and machine-learning.This platform,termed c-Air,is also integrated with a smartphone application for device control and display of results.This mobile device rapidly screens 6.5 L of air in 30 s and generates microscopic images of the aerosols in air.It provides statistics of the particle size and density distribution with a sizing accuracy of~93%.We tested this mobile platform by measuring the air quality at different indoor and outdoor environments and measurement times,and compared our results to those of an Environmental Protection Agency–approved device based on beta-attenuation monitoring,which showed strong correlation to c-Air measurements.Furthermore,we used c-Air to map the air quality around Los Angeles International Airport(LAX)over 24 h to confirm that the impact of LAX on increased PM concentration was present even at 47 km away from the airport,especially along the direction of landing flights.With its machinelearning-based computational microscopy interface,c-Air can be adaptively tailored to detect specific particles in air,for example,various types of pollen and mold and provide a cost-effective mobile solution for highly accurate and distributed sensing of air quality. | Yi-Chen Wu Ashutosh Shiledar Yi-Cheng Li Jeffrey Wong Steve Feng Xuan Chen Christine Chen Kevin Jin Saba Janamian Zhe Yang Zachary Scott Ballard Zoltán Göröcs Alborz Feizi Aydogan Ozcan | 2017 | Light(Science & Applications)2017，6，1： | 5 |
| 5 | A framework for ranking of cloud computing services显示文摘 | SAURABH K G STEVE V RAJKUMAR B | | 0，，04： | 2 |
| 6 | The Effect of Competition on the Efficiency of Secondary Schools in Eng- land 显示文摘 | Bradley Steve Johnes G Millington Jim | 2001 | European Journal of Operational Research2001，135，3： | 1 |
| 7 | Estimation of tropical forest structural characteristics using large-footprint lidar显示文摘 | Jason B Drake Ralph O Dubayah David B Clark Robert G Knox J.Bryan Blair Michelle A Hofton Robin L Chazdon John F Weishampel Steve Prince | 2001 | Remote Sensing of Environment2001，，2： | 1 |
| 8 | LIGHT, a New Member of the TNF Superfamily, and Lymphotoxin α Are Ligands for Herpesvirus Entry Mediator显示文摘 | Davide N Mauri Reinhard Ebner Rebecca I Montgomery Kristine D Kochel Timothy C Cheung Guo-Liang Yu Steve Ruben Marianne Murphy Roselyn J Eisenberg Gary H Cohen Patricia G Spear Carl F Ware | 1998 | Immunity1998，，： | 1 |
| 9 | A role for glutamate decarboxylase during tomato ripening:the eharaeterisation of a cDNA encoding a putative glutamate decarboxylase with a calmodulin binding site 显示文摘 | PEDRO P G LEE W STEVE P DON G JULIE E G | 1995 | Plant Molecular Biology1995，27，6： | 1 |
| 10 | A soft architecture and framework for web-based distributed decision support systems显示文摘 | ZHANG Shifeng STEVE G | 2007 | Decision Support Systems2007，43，3： | 1 |
| 11 | Multiple-ion-doped lithium nickel oxides as cathod materials for lithium-ion batteries显示文摘 | Wang G X Steve B Jane Y | 2003 | Journal of Power Sources2003，，： | 1 |
| 12 | Organic Greenhouse Vegetable Production显示文摘 | LANE G STEVE D | 2000 | Appropriate Technology Transfer for Rural Areas2000，1，： | 1 |
| 13 | Overbalanced Perforating Yields Negative Skins in Layered Reservoir显示文摘 | Italo P Steve G | 2006 | SPE1040992006，，： | 1 |
| 14 | A comparison of the efficiency of different surfactants for removal of crude oil from contaminated soils显示文摘 | KINGSLEY U STEVE G TURGAY P | 2006 | Chemosphere2006，62，： | 1 |
| 15 | Security awareness of computer users:A Phishing Threat Avoidance Perspective显示文摘 | Nain A G Steve R | 2014 | Computers in Human Behavior2014，38，3： | 1 |
| 16 | The relationship between land use and organochlorine compounds in streambed sediments and fish in the central Columbia Plateau,Washington and Idaho,USA显示文摘 | MARK D M STEVE J G | 1997 | Environmental toxicology1997，16，7： | 1 |
| 17 | Effects of inhibi-tion of PDEA and TNF-α on local and remote injuries following isehae- mia and reperfusion injury 显示文摘 | Danielle G Souza Geovanni D Cassali Steve Poole | 2001 | Br J Pharmacol2001，134，5： | 1 |
| 18 | A self-calibrating palmerdrought severity index显示文摘 | Nathan W Steve G Michael JH | 2004 | Journal of Climate2004，17，： | 1 |
| 19 | Integrating Wireless Sensor Networks with the Grid显示文摘 | Steve M | 2004 | IEEE Internet Computing2004，7，： | 1 |
| 20 | A comparison of the wfficiency of sifferent aurfactants for removal of crude oil from contaminated soils显示文摘 | Kingsley U Steve G Turgay P | 2006 | Chemosphere2006，62，： | 1 |
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