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| 1 | Randomized trial in malignant biliary obstruction:Plastic vs partially covered metal stents显示文摘AIM:To compare efficacy and complications of par-tially covered self-expandable metal stent(pcSEMS)to plastic stent(PS)in patients treated for malignant,infrahilar biliary obstruction.METHODS:Multicenter prospective randomized clinical trial with treatment allocation to a pcWallstent(SEMS)or a 10 French PS.Palliative patients aged≥18,for infrahilar malignant biliary obstruction and a Karnofsky performance scale index>60%from 6 participating North American university centers.Primary endpoint was time to stent failure,with secondary outcomes of death,adverse events,Karnofsky performance score and short-form-36 scale administered on a three-monthly basis for up to 2 years.Survival analyses were performed for stent failure and death,with Cox proportional hazards regression models to determine significant predictive characteristics.RESULTS:Eighty-five patients were accrued over 37mo,42 were randomized to the SEMS group and 83patients were available for analyses.Time to stent failure was 385.3±52.5 d in the SEMS and 153.3±19.8 d in the PS group,P=0.006.Time to death did not differ between groups(192.3±23.4 d for SEMS vs211.5±28.0 d for PS,P=0.70).The only significant predictor was treatment allocation,relating to the time to stent failure(P=0.01).Amongst other measured outcomes,only cholangitis differed,being more common in the PS group(4.9%vs 24.5%,P=0.029).The small number of patients in follow-up limits longitudinal assessments of performance and quality of life.From an initially planned 120 patients,only 85 patients were recruited.CONCLUSION:Partially covered SEMS result in a longer duration till stent failure without increased complication rates,yet without accompanying measurable benefits in survival,performance,or quality of life. | Peter L Moses Khalid M AlNaamani Alan N Barkun Stuart R Gordon Roger D Mitty M Stanley Branch Thomas E Kowalski Myriam Martel Viviane Adam | 2013 | World Journal of Gastroenterology2013，19，46： | 6 |
| 2 | The second ESGAR consensus statement on CT colonography显示文摘 | Emanuele Neri Steve Halligan Mikael Hellstr?m Philippe Lefere Thomas Mang Daniele Regge Jaap Stoker Stuart Taylor Andrea Laghi | 2013 | European Radiology2013，，3： | 2 |
| 3 | Microbial nitrogen cycles:physiology,genomics and applications显示文摘 | Rick W Ye Stuart M Thomas | 2001 | Ecology and Industrial Microbiology2001，4，： | 1 |
| 4 | Combination of contrast with stress echocardiography: a practical guide to methods and interpretation显示文摘 | STUART M THOMAS H M | 2004 | Cardiovasc Ultrasound2004，2，1： | 1 |
| 5 | Effect of atrial radiofrequency ablation designed to cure AF on atrial mechanical function显示文摘 | Stuart P Thoma SB Fracp M | 2000 | J Cardiovas Electrophysiol2000，11，1： | 1 |
| 6 | Resolution of Crohn's disease and complex regional pain syndrome following treatment of paratuberculosis显示文摘A cohort of family members with various chronic diseases including Crohn's disease, asthma, complex regional pain syndrome, hypothyroidism, type 1 diabetes mellitus, and lymphangiomatosis and/or evidence of infection by Mycobacterium avium subsp. paratuberculosis(MAP) are described in this series of case reports. MAP was cultured from the blood of three members affected by the first five diseases and there was accompanying elevated anti-MAP Ig G in two members. The patient affected by the sixth disease has a markedly elevated anti-MAP titer. The two patients affected by the first four diseases have been treated with a combination of anti-MAP antibiotics and ultraviolet blood irradiation therapy with resolution of the disease symptomatology and inability to culture MAP in post treatment blood samples. These case reports of patients with MAP infections provide supportive evidence of a pathogenic role of MAP in humans. | J Todd Kuenstner William Chamberlin Saleh A Naser Michael T Collins Coad Thomas Dow John M Aitken Stuart Weg Grzegorz Telega Kuruvilla John David Haas Torsten M Eckstein Maher Kali Christine Welch Thomas Petrie | 2015 | World Journal of Gastroenterology2015，21，13： | 0 |
| 7 | 研究方法学 如何解读临床试验报告中的统计图显示文摘一个统计图可能会胜过千言万语,但在医学研究中。 | Stuart J Pocock Thomas G Travison Lisa M Wruck 王淳秀(译) 单广良(校) | 2008 | 英国医学杂志中文版2008，11，4： | 0 |
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