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| 1 | Contemporary crustal tectonic movement in the southern Sichuan-Yunnan block based on dense GPS observation data显示文摘We analyzed 360 permanent and campaign GPS data from 1999 to 2017 in the southern Sichuan-Yunan block, and obtained crustal horizontal deformation in this region.Then, we derived the strain rate using a multi-scale spherical wavelet method.Results reveal a complex pattern of tectonic movement in the southern Sichuan-Yunnan block.Compared to the stable Eurasian plate, the maximum rate of the horizontal deformation in the southern Sichuan-Yunnan block is approximately 22 mm/a.The Xiaojiang fault shows a significantly lower deformation—a left-lateral strike-slip movement of 9.5 mm/a.The Honghe fault clearly shows a complex segmental deformation from the north to south.The northern Honghe fault shows 4.3 mm/a right strike-slip with 6.7 mm/a extension; the southern Honghe fault shows 1.9 mm/a right strike-slip with 1.9 mm/a extension; the junction zone in the Honghe and Lijiang–Xiaojinhe faults shows an obvious clockwise-rotation deformation.The strain calculation results reveal that the maximum shear-strain rate in this region reaches 70 nstrain/a, concentrated around the Xiaojiang fault and at the junction of the Honghe and Lijiang–Xiaojinhe faults.We note that most of the earthquakes with magnitudes of 4 and above that occurred in this region were within the high shear strain-rate zones and the strain rate gradient boundary zone, which indicates that the magnitude of strain accumulation is closely related to the seismic activities.Comparison of the fast shear-wave polarization direction of the upper-crust with the upper-mantle anisotropy and the direction of the surface principal compressive strain rate obtained from the inversion of the GPS data reveals that the direction of the surface principal compressive strain is basically consistent with the fast shear-wave polarization direction of the upper crust anisotropy, but different from the polarization direction of the upper mantle.Our results support the hypothesis that the principal elements of the deformation mechanism in the southern Sichuan-Yunnan block are decoupling between the upper and lower crust and ductile flow in the lower crust. | HongLin Jin Yuan Gao XiaoNing Su GuangYu Fu | 2019 | Earth and Planetary Physics2019，3，1： | 18 |
| 2 | Heterogeneous strain regime in the eastern margin of Tibetan Plateau and its tectonic implications显示文摘The eastern margin of Tibetan Plateau is one of the most active zones of tectonic deformation and seismicity in China. To monitor strain buildup and benefit seismic risk assessment, we constructed 14 survey-mode global position system(GPS) stations throughout the northwest of Longmenshan fault. A new GPS field over 1999–2011 is derived from measurements of the newly built and pre-existing stations in this region. Sequentially,two strain rate fields, one preceding and the other following the 2008 MW7.9 Wenchuan earthquake, are obtained using the Gausian weighting approach. Strain field over1999–2007 shows distinct strain partitioning prior to the2008 MW7.9 Wenchuan earthquake, with compression spreading over around Longmenshan area. Strain field derived from the two measurements in 2009 and 2011 shows that the area around Longmenshan continues to be under striking compression, as the pattern preceding the Wenchuan earthquake, implying a causative factor of the sequent of 2013 MW6.7 Lushan earthquake. Our GPSderived dilatation shows that both the Wenchuan and Lushan earthquakes occurred within the domain of pronounced contraction. The GPS velocities demonstrate that the Longriba fault underwent slight motion with the faultnormal and-parallel rates at 1.0 ± 2.5 mm and 0.3 ± 2.2 mm/a; the Longmenshan fault displayed slow activity, with a fault-normal rate at 0.8 ± 2.5 mm/a, and a fault-parallel rate at 1.8 ± 1.7 mm/a. Longriba fault is on a par with Longmenshan fault in strain partitioning to accommodate the southeastward motion of eastern margin of the Tibetan Plateau. Integrated analysis of principal strain tensors, mean principal stress, and fast directions of mantle anisotropy shows that west of Sichuan is characterized as mechanically strong crust-mantle coupling. | Guojie Meng Xiaoning Su Weiwei Wu Jinwei Ren Yonglin Yang Jicang Wu Chieh-Hung Chen Nikolay V.Shestakov | 2015 | Earthquake Science2015，28，1： | 5 |
| 3 | Global crustal movement and tectonic plate boundary deformation constrained by the ITRF2008显示文摘On the basis of the newly released International Terrestrial Reference Frame(ITRF2008) by the International Earth Rotation Service(IERS),a new global plate model ITRF2008 plate for the major plates is established.This ITRF2008-derived model is analyzed in comparison with NNR-NUVEL1A model,which is mainly based on geological and geophysical data.The Eurasia and Pacific plates display obvious differences in terms of the velocity fields derived from the two plate motion models.Plate acceleration is also introduced to characterize the differences of the two velocity fields which obtained from ITRF2008-plate and NNR-NUVEL1A models for major individual plates.The results show that the Africa,South America and Eurasia plates are undergoing acceleration,while the North America and Australia plates are in the state of deceleration motion. | Zhu Ze Meng Guojie Su Xiaoning Wu Jicang Li Jean Xiaojing | 2012 | Geodesy and Geodynamics2012，3，3： | 4 |
| 4 | Validation of Non-invasive Fibrosis Scores for Predicting Advanced Fibrosis in Metabolic-associated Fatty Liver Disease显示文摘Background and Aims:Metabolic-associated fatty liver disease(MAFLD)is a newly proposed terminology from 2020;yet,the applicability of conventional noninvasive fi-brosis models is still unknown for it.We aimed to evaluate the performance of conventional noninvasive fibrosis scores in MAFLD.Methods:The NHANES 2017-2018 datasets were used to compare the performances of different non-invasive fibrosis scores in MAFLD,including the aspartate aminotransferase(AST)to platelet ratio index(APRI),body mass index(BMI)-AST/alanine aminotransferase(ALT)ratio and diabetes score(BARD),fibrosis-4 index(FIB-4),and NAFLD fibrosis score(NFS).Moreover,Asian patients with biopsy-proven MAFLD were enrolled to further validate the findings.Results:A total of 2,622 participants in the Na-tional Health and Nutrition Examination Survey(NHANES)cohort and 293 patients with MAFLD in the Asian cohort were included.Patients in the Asian cohort had a lower BMI and higher liver enzymes(p<0.001).The area under the receiver operating characteristic curve(AUROC)of NFS was the largest in the NHANES cohort and Asian cohorts(0.679 and 0.699,respectively).The AUROC of NFS was followed by APRI,FIB-4,and BARD in the NHANES cohort(0.616,0.601,and 0.589,respectively).In the Asian cohort,the AUROC of APRI,FIB-4,and BARD for predicting advanced fibrosis were 0.625,0.683,and 0.615,respectively.The performance of FIB-4 was better in the Asian cohort than that in the NHANES cohort.Conclusions:NFS is better for predicting advanced fibrosis in MAFLD.FIB-4 can be an al-ternative choice for MAFLD with high liver enzymes when NFS is unavailable.Novel efficient noninvasive fibrosis scor-ing systems are highly required for patients with MAFLD. | Xiaoning Chen George Boon-Bee Goh Jiaofeng Huang Yinlian Wu Mingfang Wang Rahul Kumar Su Lin Yueyong Zhu | 2022 | Journal of Clinical and Translational Hepatology2022，10，4： | 4 |
| 5 | Engineering miniature gold nanorods with tailorable plasmonic wavelength in NIR region via ternary surfactants mediated growth显示文摘Plasmonic nanoparticles are endowed profound capability for sensing,biomedicine,and cancer therapy.However,the inaccessibly adjustable wavelength in near infrared(NIR)region window and size limit for the particles penetration in tumor strongly hinder their developments.Miniature gold nanorods(mini-Au NRs)with diameter less than 12 nm can effectively address this challenge due to the tiny size and tailorable NIR absorption.Herein,we adopt ternary surfactants(hexadecyl trimethyl ammonium bromide(CTAB),sodium oleate(NaOL),and sodium salicylate(NaSal))mediated growth strategy to precisely synthesize miniature Au NRs under micelle space-confinement.Importantly,the selectively dense accumulation of ternary surfactants can efficiently improve the micellar stacking parameters(p)and lower micellar free energy(F),further tends to achieve the formation of Au NRs with tiny diameter and high purity.Compared with that of conventional methods,the purity of mini-Au NRs up to 100%can be dramatically improved via varying the relative concentration of ternary surfactants.The diameter of Au NRs can be dynamically controlled to 6,8,and 11 nm through regulating the concentration of silver nitrate and the mole ratio of ternary surfactants.Such ternary surfactants system is favorable for the aging of tiny Au NRs,and further enables the aspect ratio-tunable in the region from 2.70 to 7.32,as well as tailorable plasmonic wavelength in wide NIR window from 700 to 1,147 nm.Therefore,our findings shed a light on the precise preparation of small sized plasmonic nanoparticles and pave the way to applications in biomedicine,imaging,and cancer therapy. | Xiaoning Luo Xiaoyuan Wang Lingli Zhang Liping Song Zhiwei Sun Yu Zhao Fengmei Su Youju Huang | 2023 | Nano Research2023，16，4： | 1 |
| 6 | Facile synthesis,high fluorescence and flame retardancy of carbon dots显示文摘Facile strategy enabling the fabrication of carbon dots(CDs)with favorable performance useful for various applications is highly desirable.Here,we report the fabrication of highly fluorescent carbon dots(CDs)towards sensitive metal ion detection,brightly fluorescent printing pattern,as well as green flame retardants for synthetic polymeric materials.CDs are synthesized by solvothermal treatment of polypropylene carbonate(PPC)with ethylenediamine,and the quantum yield of CDs could increase from 30%to 86%by further adding trace of citric acid.The abundant functional groups on the surface of CDs allow CDs well incorporated into polymers to form CD-loaded polystyrene(PS)microspheres,which are employed to construct fluorescent supraballs via triphase microfluidic technique and used as“inks”for uniform fluorescent patterns.Interestingly,the resultant CDs show good flame retardancy for highly flammable polymeric foams and fibers.The CDs surpass previously reported flame-retardant additives,to show excellent combustion resistance that the addition of 20 wt%CDs causes 75%decrease in the peak of heat release rate(P-HRR)for polyurethane(PU)foams.Significantly,a molecular dynamics simulation process for PU/CDs combustion is constructed.This work may spur the preparation and application of highperformance carbon-based nanomaterials. | Chang Liu Hongying Li Rui Cheng Jiazhuang Guo Guo-Xing Li Qing Li Cai-Feng Wang Xiaoning Yang Su Chen | 2022 | Journal of Materials Science & Technology2022，，9： | 1 |
| 7 | Identification of novel human glioblastoma-specific transcripts byserial analysis of gene expression data mining显示文摘 | Yanlin Su Jie Xiong Zhitong Bing Xiaomin Zeng Yong Zhang Xiaohua Fu Xiaoning Peng | 2013 | Cancer Biomarkers2013，，5： | 1 |
| 8 | Rigid POSS Nanofiller Regulated the Interfacial Self-assembly of Particles into 2D Monolayer Superlattice with Fixed Interparticle Spacing显示文摘Plasmonic superlattices of nanoparticles(NPs)possess unique“surface lattice resonances”properties that facilitates their wide applications in plasmonic sensing,photocatalysis,and nanoscale light manipulation.However,it is still challenging to manufacture superlattices with precisely controllable NPs distance and break the size limitation of NPs.Herein,we provided an effective strategy to construct NPs superlattices via shape-persistent polyhedral oligosilsesquioxane(POSS)molecular nanoparticles govern interfacial assembly.As a nanoscale molecule with diameter of 1.5 nm,the POSS-SH molecule provides sufficient rigid steric hindrance and hydrophobic effect for tailoring the uniformity and controllable distance between NPs in superlattices.Interestingly,synergistically with hydrophilic ligands of polyethylene glycol(PEG-SH)with optimized ratio,the rigid POSS ligands can effectively regulate the distance between NPs in a fixed range of 2.3—2.8 nm,which is independent of ligands molecular weight and particle size.Furthermore,the effective approach can be universal to anisotropic NPs for manufacturing monolayer films with high NPs density.We believe this nanoscale molecule tailored interfacial self-assembly strategy can effectively break the size of NPs and assembly obstacles for superlattice monolayer film.Additionally,the definite distance between NPs in superlattices can minimize optical energy attenuation and facilitates the applications such as surface-enhanced Raman spectroscopy and photocatalysis. | Yu Zhao Xiaoyuan Wang Xiaoning Luo Liping Song Fengmei Su Youju Huang | 2023 | Chinese Journal of Chemistry2023，41，3： | 0 |
| 9 | 基于激光三角法的电装后PCB成像系统设计显示文摘With the increasing miniaturisation and integration of electronic products and the increase of heat, it is necessary to design and introduce heat sinks and install fans. The volume of electronic components, especially the height, is very important for the structural and thermal design of electronic devices. This paper presents a design scheme of an online height measurement device based on laser triangulation and commercial charge coupled device(CCD). It analyzes the principles of electronic component height measurement, and expounds the composition and working principle of the laser measurement system. In addition, the commonly used methods to determine the center position are compared and analysed. These methods include circle fitting, gray centroid and extension method or Gaussian fitting. These methods usually lead to different results. The experimental results show that the fitting speed of the gray centroid is faster. The 3 D model of components is given through measurement, and the error factors affecting measurement are analysed. | LIU Qingfeng LI Bo WANG Qi ZHAO Sheng AN Wanqing SU Xinming LIU Xiaoning ZHU Xi | 2021 | Aerospace China2021，22，4： | 0 |
| 10 | MSCs-derived apoptotic extracellular vesicles promote muscle regeneration by inducing Pannexin 1 channel-dependent creatine release by myoblasts显示文摘Severe muscle injury is hard to heal and always results in a poor prognosis.Recent studies found that extracellular vesicle-based therapy has promising prospects for regeneration medicine,however,whether extracellular vesicles have therapeutic effects on severe muscle injury is still unknown.Herein,we extracted apoptotic extracellular vesicles derived from mesenchymal stem cells(MSCs-Apo EVs)to treat cardiotoxin induced tibialis anterior(TA)injury and found that MSCs-Apo EVs promoted muscles regeneration and increased the proportion of multinucleated cells.Besides that,we also found that apoptosis was synchronized during myoblasts fusion and MSCs-Apo EVs promoted the apoptosis ratio as well as the fusion index of myoblasts.Furthermore,we revealed that MSCs-Apo EVs increased the relative level of creatine during myoblasts fusion,which was released via activated Pannexin 1 channel.Moreover,we also found that activated Pannexin 1 channel was highly expressed on the membrane of myoblasts-derived Apo EVs(Myo-Apo EVs)instead of apoptotic myoblasts,and creatine was the pivotal metabolite involved in myoblasts fusion.Collectively,our findings firstly revealed that MSCs-Apo EVs can promote muscle regeneration and elucidated that the new function of Apo EVs as passing inter-cell messages through releasing metabolites from activated Pannexin 1 channel,which will provide new evidence for extracellular vesicles-based therapy as well as improving the understanding of new functions of extracellular vesicles. | Qingyuan Ye Xinyu Qiu Jinjin Wang Boya Xu Yuting Su Chenxi Zheng Linyuan Gui Lu Yu Huijuan Kuang Huan Liu Xiaoning He Zhiwei Ma Qintao Wang Yan Jin | 2023 | International Journal of Oral Science2023，15，1： | 0 |
| 11 | Easy-to-perform organic-solvent-free synthesis of carbon dots with strong green photoluminescence显示文摘Carbon dots(CDs)have been extensively studied owing to their fascinating optical properties and wide potential applications.Here,we report an easy-to-perform and organic-solvent-free synthesis strategy for green-emissive CDs(G-CDs)possessing high photoluminescence(PL)quantum yield(QY).The G-CDs are synthesized by heating the homogeneous precursors of citric acid and cyanamide in an open vessel,circumventing the use of organic solvents,complex operations,high-pressure reactors,and expensive instruments in the synthesis process.The effect of various reaction variables on the formation and the optical properties of G-CDs are systematically investigated.The resultant G-CDs show bright PL emission at 521 nm with PL QY up to 73%.Then a white light-emitting diode(LED)with Commission Internationable de L'Eclairage(CIE)coordinates of(0.33,0.34)and color rendering index(CRI)of 92 is constructed based on G-CDs/thermoplastic polyurethane(TPU)composite.Moreover,a visual microfluidic detection platform is designed by using G-CDs as fluorescent probes for rapid quantitative detection of Fe^(3+),Cu^(2+),and Mn^(2+)metal ions,which can realize synchronized testing of multiple samples.This study might promote the development and preparation methods of high-performance CDs with various optical applications. | Jiazhuang Guo Yifeng Chen Pan Zhang Ge Li Xiaoning Yang Cai-Feng Wang Su Chen | 2024 | Chinese Chemical Letters2024，35，3： | 0 |
| 12 | The role of endotoxin in the pathogenesis of gastric mucosal damage in cirrhotic rats with portal hypertensive gastropathy显示文摘Objective:To study the role and the mechanism of endotoxin in the pathogenesis of gastric mucosa during portal vein hypertension gastrography(PHG) in the rats with cirrhosis.Methods: Rat model for PHG was established by injection of tetrachloride.The animals were injected with endotoxin i.p.at 3 mg/kg and endotoxin antagonist BPI21 i.v.at 2.0 mg/kg.The plasma level of endotoxin as well as the gastric mucosal level of tumor necrosis factor alpha(TNF-α) was measured with azobenzene and ELISA respectively.Furthermore,the pathological changes of the gastric mucosa were studied with HE stainning.Results:In rats with PHG,increased endotoxin and TNF-αas well as the gastric pathological lesion were observed.Injection of endotoxin remarkably increased plasma level of endotoxin as well as the gastric mucosal level of tumor necrosis TNF-αand induced more serious gastric lesion.Animals injected with endotoxin antagonist BPI21 showed improved gastric mucosal lesion,accompanied by the declining TNF-αlevel.Conclusions:Our results suggestes that endotoxin may play a pathogenetic role in PHG by inducing the expression of TNF-α. | Cheng Lan Xiaoning Sun Liwei Dong Baili Huang Su Yuan Keli Wu | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，3： | 0 |
| 13 | AIM-CICs: an automatic identification method for cell-in-cell structures based on convolutional neural network显示文摘Whereas biochemical markers are available for most types of cell death, current studies on non-autonomous cell death by entosis rely strictly on the identification of cell-in-cell structures (CICs), a unique morphological readout that can only be quantified manually at present. Moreover, the manual CIC quantification is generally over-simplified as CIC counts, which represents a major hurdle against profound mechanistic investigations. In this study, we take advantage of artificial intelligence technology to develop an automatic identification method for CICs (AIM-CICs), which performs comprehensive CIC analysis in an automated and efficient way. The AIM-CICs, developed on the algorithm of convolutional neural network, can not only differentiate between CICs and non-CICs (the area under the receiver operating characteristic curve (AUC) > 0.99), but also accurately categorize CICs into five subclasses based on CIC stages and cell number involved (AUC > 0.97 for all subclasses). The application of AIM-CICs would systemically fuel research on CIC-mediated cell death, such as high-throughput screening. | Meng Tang Yan Su Wei Zhao Zubiao Niu Banzhan Ruan Qinqin Li You Zheng Chenxi Wang Bo Zhang Fuxiang Zhou Xiaoning Wang Hongyan Huang Hanping Shi Qiang Sun | 2022 | Journal of Molecular Cell Biology2022，14，6： | 0 |
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