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| 1 | Cerebral mechanism of puncturing at He-Mu point combination for functional dyspepsia: study protocol for a randomized controlled parallel trial显示文摘Acupuncture is widely used to treat functional dyspepsia with satisfactory outcomes. Combination of the He and Mu acupoints is commonly used and has a synergistic effect on functional dyspepsia; however, its underlying mechanisms remain unclear. Therefore, a randomized controlled parallel clinical trial is currently underway at Chengdu University of Traditional Chinese Medicine, China. This trial is designed to explore the efficacy of and central responses to the He-Mu point combination in patients with functional dyspepsia using functional magnetic resonance imaging. A total of 105 patients with functional dyspepsia will be allocated into 3 groups: the low-He point group(puncturing at Zusanli(ST36)), Mu point group(puncturing at Zhongwan(CV12)), and He-Mu point combination group(puncturing at ST36 and CV12). Every participant will receive 20 sessions of manual acupuncture for 4 weeks. The needles will be inserted perpendicularly to a depth of 1 to 2 cun. The angle of rotation and twisting will range from 90 to 180 degrees, while lifting and thrusting will range from 0.3 to 0.5 cm. The various manipulations will be performed 60 to 90 times per minute. The needles will remain in place for 30 minutes, during which manipulation will be applied every 10 minutes. Magnetic resonance imaging will be performed before and after 20 sessions of acupuncture. The primary outcome is symptom improvement according to the Chinese version of the Nepean Dyspepsia Index. Secondary outcomes include the Leeds dyspepsia questionnaire, Self-Rating Anxiety Scale, Self-Rating Depression Scale, Beck Anxiety Inventory, Beck Depression Inventory, and visual analogue scale scores before and after 10 and 20 sessions of acupuncture. Needle sensation and adverse events will be used to assess the therapeutic effects. This study will promote more widespread awareness of the benefits of acupoint combination in the clinical setting and provide a further explanation of the neuromechanism by which acupuncture at the He-Mu point combination for functional dyspepsia. Registration: Chinese Clinical Trial Registry, Chi CTR-IOR-15006402. | Shuai Yin Yuan Chen Du Lei Rui-rui Sun Ting-ting Ma Pei-min Feng Zhao-xuan He Xue-ling Suo Pei-hong Ma Yu-zhu Qu Ke Qiu Miao-miao Jing Qi-yong Gong Fan-rong Liang Jiao Chen Fang Zeng | 2017 | Neural Regeneration Research2017，12，5： | 9 |
| 2 | ILC3-derived OX40L is essential for homeostasis of intestinal Tregs in immunodeficient mice显示文摘OX40L is one of the co-stimulatory molecules that can be expressed by splenic lymphoid tissue inducer(Lti)cells,a subset of group 3 innate lymphoid cells(ILC3s).OX40L expression in subsets of intestinal ILC3s and the molecular regulation of OX40L expression in ILC3s are unknown.Here,we showed intestinal ILC3s marked as an OX40L high population among all the intestinal leukocytes and were the dominant source of OX40L in Rag1–/–mice.All ILC3 subsets expressed OX40L,and NCR–ILC3s were the most abundant source of OX40L.The expression of OX40L in ILC3s could be upregulated during inflammation.In addition to tumor necrosis factor(TNF)-like cytokine 1A(TL1A),which has been known as a trigger for OX40L,we found that Poly(I:C)representing viral stimulus promoted OX40L expression in ILC3s via a cell-autonomous manner.Furthermore,we demonstrated that IL-7-STAT5 signaling sustained OX40L expression by ILC3s.Intestinal regulatory T cells(Tregs),most of which expressed OX40,had defective expansion in chimeric mice,in which ILC3s were specifically deficient for OX40L expression.Consistently,co-localization of Tregs and ILC3s was found in the cryptopatches of the intestine,which suggests the close interaction between ILC3s and Tregs.Our study has unveiled the crosstalk between Tregs and ILC3s in mucosal tissues through OX40–OX40L signaling,which is crucial for the homeostasis of intestinal Tregs. | Tian Deng Caixia Suo Jiali Chang Rui Yang Jingyu Li Ting Cai Ju Qiu | 2020 | Cellular & Molecular Immunology2020，17，2： | 3 |
| 3 | Molecular evidence for natural hybridization between Sonneratia alba and S. griffithii显示文摘Interspecific hybridization has been frequently observed in the mangrove genus Sonneratia. However, no natural hybridization has been reported between Sonneratia alba and S. griffithii to date, despite their overlap-ping distribution in the coast of Andaman Sea. In this study, cysteine proteinase inhibitor gene (cpi) from the nuclear genome, and two intergenic spacers (trnL-trnF and trnV-trnM) from the chloroplast genome, were se-quenced to determine whether natural hybridization took place between the two species. Our results revealed two distinct types of cpi sequences from the putative hybrid matching those acquired from S. griffithii and S. alba, respectively. Sequencing of the chloroplast trnL-trnF and trnV-trnM regions showed that S. alba differed from S. griffithii by one nucleotide in each region, and the putative hybrid had the identical sequences with S. griffithii. Molecular data demonstrated clearly that there indeed existed natural hybridization between S. alba and S. grif-fithii, and that S. griffithii was the maternal parent in this hybridization event. | Suo QIU Ren-Chao ZHOU Yun-Qin LI Sonjai HAVANOND Chanop JAENGJAI Su-Hua SHI | 2008 | 植物分类学报2008，46，3： | 2 |
| 4 | Microstructure and mechanical properties of bulk Mg-Zn-Ca amorphous alloys and amorphous matrix composites显示文摘 | LI Q F WENG H R SUO Z Y REN Y L YUAN X G QIU K Q | 2008 | Mater Sci Eng A2008，487，： | 1 |
| 5 | Microstructure and mechanical properties of bulk Mg-Zn-Ca amorphous alloys and amorphous matrix composites显示文摘 | LI Q F WENG H R SUO Z Y REN Y L YUAN X G QIU K Q | 2008 | Materials Science and Engineering A2008，487，： | 1 |
| 6 | Effect of Co Addition on the Glass-Forming Ability and Mechanical Properties of Ti-Zr-Be-Cu-Co Bulk Amorphous Alloys显示文摘 | Suo Zhong Yuan Song Yan Ling Qiu Ke Qiang | 2012 | 2012 (182)2012，，182： | 1 |
| 7 | Effect of Co addition on the glass-forming ability and mechanical properties of Ti-Zr-Be Cu- Co bulk amorphous alloys显示文摘 | Suo Z Y Song Y L Qiu K Q | 2012 | Applied Mechanics and Materials2012，182，183： | 1 |
| 8 | Observation of shear bands formation on tungsten fiber-reinforced Zr-based bulk metallic glass matrix composite 显示文摘 | QIU K Q SUO Z Y REN Y L YU B | 2007 | Journal of Materials Research2007，22，： | 1 |
| 9 | 显示文摘 | Qiu K Q Suo Z Y Ren Y L | 2007 | Journal of Materials Research2007，22，： | 1 |
| 10 | Ti-Cu-Ni alloys with high strength and good plastieity显示文摘 | SUO Z Y QIU K Q LI Q F | 2008 | Journal o Alloys and Compounds2008，463，56： | 1 |
| 11 | Effect of Co addition on the glass-forming ability and mechanical properties of Ti-Zr-Be-Cu-Co bulk amorphous alloys显示文摘 | SUO Z Y SONG Y L QIU K Q | 2012 | Applied Mechanics and Materials2012，18，2183： | 1 |
| 12 | Effect of Co addition on the glass-forming ability and mechanical properties of Ti - Zr- Be - Cu - Co bulk amorphous alloys 显示文摘 | SUO Z Y SONG Y L QIU K Q | 2012 | Applied Mechanics and Materials2012，，： | 1 |
| 13 | Kinetics and reaction mechanism of phenol hydroxylation catalyzed by La-Cu_4FeAlCO_3显示文摘The present work synthesizes La-Cu4FeAlCO3 catalyst under microwave irradiation and characterizes its structure using XRD and IR techniques. The results show that the obtained La-Cu4FeAlCO3 has a hydrotalcite structure. In the phenol hydroxylation with H2O2 catalyzed by La-Cu4FeAlCO3, the effects of reaction time and phenol/H2O2 molar ratio on the phenol hy-droxylation, and relationships between the initial hydroxylation rate with concentration of the catalyst, phenol, H2O2 and reaction temperature are also investigated in details. It is shown the phenol conversion can reach 50.09% (mol percent) in the phenol hydroxylation catalyzed by La-Cu4FeAlCO3, under the reaction conditions of the molar ratio of phenol/H2O2 1/2, the amount ratio of phenol/catalyst 20, reaction temperature 343 K, reaction time 120 min, 10 mL distilled water as solvent. Moreover, a kinetic equation of v = k[La ? Cu 4 FeAlCO 3 ][C 6 H 5 OH][H 2 O 2]. and the activation energy of Ea=58.37 kJ/mol are obtained according to the kinetic studies. Due to the fact that the HO-Cu+-OH species are detected in La-Cu4FeAlCO3/H2O2 system by XPS, the new mechanism about the generation of hydroxyl free radicals in the phenol hydroxylation is pro-posed, which is supposed that HO-Cu+-OH species are transition state in this reaction. | CHEN Chunxia1,2, XU Chenghua1, FENG Liangrong1, SUO Jishuan1 & QIU Fali1 1. Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu 610041, China 2. Graduate School of the Chinese Academy of Sciences, Beijing 100039, China | 2005 | Science China Chemistry2005，48，6： | 1 |
| 14 | Crystallization kinetics of misch metal based bulk metallic glasses显示文摘 | WU X F MENG L K ZHAO W SUO Z Y SI Y QIU K Q | | 0，，： | 1 |
| 15 | Nickel foam reinforced AZ91 magnesium alloy显示文摘 | QIU K Q LIU Y Q SUO Z Y REN Y L LIU Z | 2007 | Materials Science Forum2007，，： | 1 |
| 16 | Fabrication of n-SiO2 Reinforced A1203 Composites Coatings on 7A52 Aluminum Alloy by Mieroare Oxidation 显示文摘 | MA S N SUO X B QIU J | 2010 | Advanced Materials Research2010，，： | 1 |
| 17 | Fabrication of ttmgsten- based metallic glasses by low purity industrial raw materials显示文摘 | SUO Z Y SONG Y L YU B QIU K Q | 2011 | Materials Science and Engineering A2011，528，6： | 1 |
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