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| 1 | An atomic force microscopy study of coal nanopore structure显示文摘Coal nanopore structure is an important factor in understanding the storage and migration of absorbed gas in coal. A new method for studying coal nanopore structures is proposed. This idea is based on the nano-level resolution of atomic force microscopy, which can be employed to observe the structural features of coal nanopores clearly, conduct quantitative three-dimensional measurements and obtain structural parameters. Analysis results show that coal nanopores are mainly metamorphic pores and intermolecular pores. The metamorphic pores are commonly rounded and elliptical, increasing quantitatively with the coalification degree. The forms of intermolecular pores change markedly. The average pore size of low-rank coal is bigger than high-rank coal, and the number of intermolecular pores decreases as the coal rank increases. Section analysis effectively characterizes the coal pore microstructure, bearing analysis is a vital approach to measure microporosity, and grain analysis can be employed to study the pore size distribution. Atomic force microscopy is a tool for the in-depth research of coal pore microstructure and the coal-bed methane adsorption mechanism. | YAO SuPing JIAO Kun ZHANG Ke HU WenXuan DING Hai LI MiaoChun PEI WenMing | 2011 | Chinese Science Bulletin2011，56，25： | 30 |
| 2 | Detection of water in petroleum inclusions and its implications显示文摘FTIR spectra of inclusions sampled from fault-zone reservoirs of the northwestern Junggar Basin show that water, with different abundances, does exist in petroleum inclusions. It is thus implied that petroleum inclusions can seldom form without water. Different inclusions hosted in one single grain, and formed in one oil charging phase, have a largely varied ratio of water to oil and slightly changed CH3/CH2 ratio. This likely provides evidence for fault-related episodic migration and accumulation of hydrocarbons. | CAO Jian YAO Suping HU Wenxuan ZHANG Yijie WANG Xulong ZHANG Yueqian TANG Yong | 2006 | Chinese Science Bulletin2006，51，12： | 9 |
| 3 | Discovery of low-mature hydrocarbon in manganese nodules and ooze from the Central Pacific deep sea floor显示文摘Extracts from manganese nodules and ooze from the Central Pacific deep sea floor were analyzed using the chromatogram-mass spectrum, and it was found that most of the biomarker molecules are of the low-mature type (some have characteristics of mature): the ratio of 'A'/C is high between 11.4%-19.75%; CPI is 1.22-1.23; C31-22S/ (22S+22R) hopane is 0.59-0.60, Tm/Ts is 0.99-1.99; pa moretane/(αβ+βα) hopane is 0.12-0.14; C29 sterane 20S/(20S+20R) is 0.35-0.41; ββ/(ββ+αα) is 0.38-0.45; arene TA(I)/TA(I+Ⅱ) is 0.16-0.21; methyl-phenanthrene index (MPI1) is 0.35-0.67. According to the geological settings of the sampling area and its organic geochemical characteristics, it is considered that the hydrothermal activities on the ocean floor facilitate the decomposition of organic matter in the sediment, which leads to the generation and migration of hydrocarbon into manganese nodules and ooze. This discovery is important for understanding the mechanisms of hydrocarbon generation in the ocean floor and | HU Wenxuan JIN Zhijun YAO Suping LU Xiancai CHEN Zhilin ZHANG Linye ZHANG Xuejun ZHOU Huaiyang | 2002 | Chinese Science Bulletin2002，47，11： | 7 |
| 4 | Assessment of antibiotic prescription in hospitalized patients at a Chinese university hospital显示文摘 | Suping Hu Xiuheng Liu Yan Peng | 2003 | J Infect2003，46，3： | 1 |
| 5 | Assessment of Antibiotic Prescription in Hospitalised Patients at a Chinese University Hospital显示文摘 | Suping Hu Xiuheng Liu Yan Peng | 2003 | Journal of Infection2003，，3： | 1 |
| 6 | Petroleum migration and mixing in the northwestern Junggar Basin (NW China): constraints from oil-bearing fluid inclusion analyses显示文摘 | Jian Cao Suping Yao Zhijun Jin Wenxuan Hu Yijie Zhang Xulong Wang Yueqian Zhang Yong Tang | 2006 | Organic Geochemistry2006，，： | 1 |
| 7 | Polymorphisms involved in the miR-218 - LAMB3 pathway and susceptibility of cervical cancer, a case–control study in Chinese women显示文摘 | Xiaoyi Zhou Xiaojun Chen Lingmin Hu Suping Han Fulin Qiang Yuling Wu Li Pan Hongbing Shen Ying Li Zhibin Hu | 2010 | Gynecologic Oncology2010，，2： | 1 |
| 8 | Polymorphisms involved in the miR-218 - LAMB3 pathway and susceptibility of cervical cancer, a case–control study in Chinese women显示文摘 | Xiaoyi Zhou Xiaojun Chen Lingmin Hu Suping Han Fulin Qiang Yuling Wu Li Pan Hongbing Shen Ying Li Zhibin Hu | 2010 | Gynecologic Oncology2010，，2： | 1 |
| 9 | Deciphering the Early Cretaceous transgression in coastal southeastern China: Constraints based on petrography, paleontology and geochemistry显示文摘 | Guang Hu Wenxuan Hu Jian Cao Suping Yao Xiaomin Xie Yongxiang Li Youxiang Liu Xueyin Wang | 2012 | Palaeogeography, Palaeoclimatology, Palaeoecology2012，，： | 1 |
| 10 | Improved Understanding of Petroleum Migration History in the Hongche Fault Zone显示文摘 | Jian Cao Zhijun Jin Wenxuan Hu Yijie Zhang Suping Yao Xulong Wang Yucqian Zhang Yong Tang | 2010 | Northwestern Junggar Basin (northwest China): Constrained by vein-calcite fluid inclusions and trace elements Marine and Petroleum Geology2010，27，： | 1 |
| 11 | Chemically modified konjac glucomannan with high colloid osmotic pressure: Physiological evalu- ation in a rabbit model as a plasma substitute, 显示文摘 | Suping Li Tao Hu Yali Chen | 2010 | Glycobiology2010，20，8： | 1 |
| 12 | The Permian hybrid petroleum system in the northwest margin of the Junggar Basin, northwest China显示文摘 | Jian Cao Yijie Zhang Wenxuan Hu Suping Yao Xulong Wang Yueqian Zhang Yong Tang | 2005 | Marine and Petroleum Geology2005，，3： | 1 |
| 13 | Comprehensive Diagnostic Value of P53, p21WAF1 and Proliferating Cell Nuclear Antigen for Lung Cancer显示文摘The expression of P53, p21WAF1 and proliferating cell nuclear antigen (PCNA) was detected in 114 samples of lung cancer patients (with 89 cases benign lung tissue as control) and the diagnostic value of these markers was evaluated. The results show the following: ① The positive expression rates of P53, p21WAF1 and PCNA in samples of lung cancer were 47.37%, 75.44% and 80.70%, respectively, which were significantly higher than that in the samples of benign lung diseases ( p ∧0.001). The odds ratios were 39.15, 5.75, and 6.76, respectively. This indicates that the expression of P53, p21WAF1 and PCNA was helpful for the diagnosis of lung cancer. ② For the diagnosis of lung cancer, the positive likelihood ratio of P53 was 21.08, which were significantly higher than that of p21WAF1 (2.16), PCNA (2.11) and of all the combined tests. This shows that P53 expression was the most valuable for diagnosis of lung cancer. ③ For the diagnosis of lung cancer, the negative likelihood ratio of P53/p21WAF1/PCNA parallel test was 0.057 1, which was lower than that of other single and combined tests. This indicates that P53/p21WAF1/PCNA parallel test has high diagnostic value for exclusion of lung cancer. | WU Xiaojun,DING Xuhong,HU Suping Department of Respiratory Diseases,Renmin Hospital of Wuhan University,Wuhan 430060,Hubei,China | 2009 | Wuhan University Journal of Natural Sciences2009，14，5： | 1 |
| 14 | Status of Stratigraphy Research in China显示文摘Scientific research and productive practice for earth history are inseparable from the accurate stratigraphic framework and time framework. Establishing the globally unified, precise and reliable chronostratigraphic series and geological time series is the major goal of the International Commission on Stratigraphy(ICS). Under the leadership of the ICS, the countries around the world have carried out research on the Global Standard Stratotype-section and Points(GSSPs) for the boundaries of chronostratigraphic systems. In the current International Chronostratigraphic Chart(ICC), 65 GSSPs have been erected in the Phanerozoic Eonothem, and one has yet been erected in the Precambrian Eonothem. Based on the progress of research on stratigraphy especially that from its subcommissions, the ICS is constantly revising the ICC, and will publish a new International Stratigraphic Guide in 2020. After continual efforts and broad international cooperation of Chinese stratigraphers, 10 GSSPs within the Phanerozoic Eonothem have been approved and ratified to erect in China by the ICS and IUGS. To establish the standards for stratigraphic division and correlation of China, with the support from the Ministry of Science and Technology, the National Natural Science Foundation of China and the China Geological Survey, Chinese stratigraphers have carried out research on the establishment of Stages in China. A total of 102 stages have been defined in the 'Regional Chronostratigraphic Chart of China(geologic time)', in which 59 stages were studied in depth. In 2014, the 'Stratigraphic Chart of China' was compiled, with the essential contents as follows: the correlation between international chronostratigraphy and regional chronostratigraphy of China(geologic time), the distributive status of lithostratigraphy, the characteristics of geological ages, the biostratigraphic sequence, the magnetostratigraphy, the geological events and eustatic sea-level change during every geological stage. The 'Stratigraphical Guide of China and its Explanation(2014)' was also published. Chinese stratigraphers have paid much attention to stratigraphic research in south China, northeast China, north China and northwest China and they have made great achievements in special research on stratigraphy, based on the 1:1000000, 1:250000, 1:200000 and 1:50000 regional geological survey projects. Manifold new stratigraphic units were discovered and established by the regional geological surveys, which are helpful to improve the regional chronostratigraphic series of China. On the strength of the investigation in coastal and offshore areas, the status of marine strata in China has been expounded. According to the developing situation of international stratigraphy and the characteristics of Chinese stratigraphic work, the contrast relation between regional stratigraphic units of China and GSSPs will be established in the future, which will improve the application value of GSSPs and the standard of regional stratigraphic division and correlation. In addition, the study of stratigraphy of the Precambrian, terrestrial basins and orogenic belts will be strengthened, the Stratigraphic Chart of China will be improved, the typical stratigraphic sections in China will be protected and the applied study of stratigraphy in the fields of oil and gas, solid minerals, etc. will be promoted. On the ground of these actions, stratigraphic research will continue to play a great role in the social and economic development of China. | YAO Jianxin BO Jingfang HOU Hongfei WANG Zejiu MA Xiulan LIU Fengshan HU Guangxiao JI Zhansheng WU Guichun WU Zhenjie LI Suping GUO Caiqing LI Ya | 2016 | Acta Geologica Sinica(English Edition)2016，90，4： | 0 |
| 15 | Characterizing the maturity of highly evolved organic matter based on aromatic hydrocarbons and optimization with pyrobitumen reflectance and Raman spectral parameters显示文摘Maturity evaluation of highly evolved organic matter is an important problem in oil and gas geochemistry,because conventional organic geochemical proxies are not applicable due to hydrocarbon generation and expulsion.In this study,we investigated the pyrobitumen in the reservoirs of the Sinian Dengying Formation in the Sichuan Basin,China.We focused on aromatic hydrocarbon biomarkers,and the calibration and application of aromatic maturity proxies using pyrobitumen reflectance and Raman spectral parameters.Our results show that only the thiophene compounds are effective maturity indicators,such as MDR(4-/1-MDBT),MDR′(4-MDBT/(1-MDBT+4-MDBT)),MDR1(1-MDBT/DBT),4,6-/(1,4+1,6)-DMDBT,(2,6+3,6)-/(1,4+1,6)-DMDBT,and[2,1]BNT/([2,1]BNT+[1,2]BNT),as these are largely independent of the optical anisotropy of pyrobitumen.The condensation and incorporation of thiophene compounds can lead to an increase in the reflectance of pyrobitumen,which means the thiophene compound parameters are positively or negatively correlated with pyrobitumen reflectance.New potential maturity parameters were proposed,including DMDBTs/MDBTs,TeMDBTs/(DBT+MDBTs+DMDBTs+TMDBTs+TeMDBTs),1-MDBT/MDBTs,and[2,1]BNT/BNTs.This method and these parameters are universally applicable to maturity characterization,especially in rocks that lack vitrinite,contain strongly anisotropic organic matter,and have high contents of thiophene compounds. | Zhaoxi ZUO Jian CAO Wenxuan HU Chunhua SHI Xiaolin WANG Suping YAO Bing LUO | 2022 | Science China Earth Sciences2022，65，12： | 0 |
| 16 | Calculation of Differential Vacuum System of HIRFL-TR2显示文摘In order to carry on research work in the field of super-heavy nuclei, our institute plans to build up a new system in HIRFL-TR2 terminal. The working pressure in target chamber is 100 Pa and the working pressure in beam line is lower than 10-5 Pa. It is almost impossible to achieve this transition through a single tube because the distance between target chamber and beam line is only 2 m. So it is necessary for us to design a set of multistage differential vacuum system. The principle of differential vacuum system is showed as Fig. 1. | Meng Jun,Yang Xiaotian, Zhang Suping, Hou Shengjun and Hu Zhenjun | 2005 | 近代物理研究所和兰州重离子加速器实验室年报:英文版2005，，1： | 0 |
| 17 | Group classification of mixed oils in central Junggar Basin,Northwest China and their migration显示文摘The produced oils in central Junggar Basin are commonly mixed in origin.In this paper,in order to reveal this complexity and thereby provide valuable clues to the study of oil source and formation mechanism,genetic groups of the mixed oils were classified and their migration/accumulation was investigated.Based on the artificial oil mixing experiments,some representative biomarkers of the mixed oils showed varying tendencies according to mixing ratios of the oils.Hence,these biomarkers are useful for determining the origin of the mixed oils.According to the criteria,oils in the area were divided into four basic groups,i.e.,the Lower Permian Fengcheng oil,the Middle Permian Lower Wuerhe oil,the Jurassic source derived oil,and the mixed oil(including the Lower and Middle Permian mixed oil and the Permian and Jurassic mixed oil).Oil migration and accumulation were discussed in combination with the geological background. | WANG Xulong SHI Xinpu CAO Jian LAN Wenfang TAO Guoliang HU Wenxuan YAO Suping | 2010 | Chinese Journal Of Geochemistry2010，29，4： | 0 |
| 18 | Detection of coalbed fractures with P-wave azimuthal AVO in 3-D seismic exploration显示文摘The detection of fractures is important for production and safety in coal fields. Subsurface fractures result in azimuthal anisotropy of the seismic wave, and the amplitude of reflection wave varies with offset and azimuth. In case of weak anisotropy, the reflection coefficients of P-wave are concisely denoted as the analytic function of fracture parameters. For the purpose of predicting the coal-bed fracture distribution through analyzing variation of the reflection amplitudes with offset and azimuth, 3-D seismic data with full-azimuth were acquired in a coal field in Huainan, Anhui Province. The careful analysis and process of seismic data showed that the reflection amplitude of the primary coalbed varied with azimuth in much consistent with the theoretical model. The conclusion was drawn that the coal-bed fracture in this coal field could be predicted through the method of the P-wave azimuthal AVO. | Guofa Li Suping Peng Bingshou He Xiaobo Peng Chunfang Yuan Chaoyuan Hu | 2005 | Chinese Science Bulletin2005，50，S1： | 0 |
| 19 | Authigenic clay minerals and calcite dissolution influence reservoir quality in tight sandstones:Insights from the central Junggar Basin,NW China显示文摘Authigenic clays and calcite cements are important in the development of reservoir tightness and the formation of hydrocarbon sweet spots.We investigated Jurassic low-permeability sandstone reservoirs in the central Junggar Basin,NW China,using petrography,mineralogy,porosity,and permeability assessment,and stable C and O isotope analysis to ascertain the influence of authigenic clays and calcites on reservoir quality.Here,we establish the properties and diagenetic processes of the reservoir sandstones,and construct a generalizable model of reservoir quality.The results show that the sandstones are mainly litharenite and feldspathic litharenite and can be classified into ductile-lithic-rich sandstones and ductile-lithic-poor sandstones according to rock composition.The ductile-lithic-rich sandstones are tight(mean porosity?7.31%;mean permeability?0.08 mD)as a result of intense compaction.In contrast,the ductile-lithic-poor sandstones can be classified into five types according to diagenetic process.The formation of favorable hydrocarbon reservoir properties is closely related to the presence of authigenic clays and dissolution of calcite.In particular,kaolinite fills intergranular pores,thereby blocking pore space and reducing reservoir quality.Chlorite coating resists compaction and limits the formation of quartz overgrowths,thereby preserving pore space and enhancing reservoir quality.Calcite controls reservoir quality through both precipitation and dissolution.Calcite precipitation results in reduced reservoir quality,whereby early calcites that were precipitated in formation water resist compaction and provide the basis for subsequent dissolution and late precipitation,whereas dissolution of calcite in mesodiagenesis improves reservoir quality.A generalized model is formulated by relating diagenetic facies types to depth and porosity,providing a reference for other similar reservoirs.Our data suggest that deeply buried tight sandstones can be exploration prospects under favorable conditions involving the presence of authigenic clays and dissolution of calcite,as in the central Junggar Basin of this study. | Dongdong Hong Jian Cao Tao Wu Sisi Dang Wenxuan Hu Suping Yao | 2020 | Energy Geoscience2020，1，1： | 0 |
| 20 | NEDD4L inhibits cell viability,cell cycle progression,and glutamine metabolism in esophageal squamous cell carcinoma via ubiquitination of c-Myc显示文摘Esophageal squamous cell carcinoma(ESCC)is a common subtype of esophageal cancer with high incidence.Surgery remains the main strategy for treatment of ESCC at early stage.However,the treatment outcome is unsatisfactory.Therefore,finding new therapeutics is of great importance.In the present study,we measured the level of NEDD4L,an ubiquitin protein ligase,in clinical samples and investigated the effects of NEDD4L on cell viability,cell cycle progression,and glutamine metabolism in TE14 cells determined by CCK-8 assay,flow cytometry and biochemical analysis,respectively.The results show that NEDD4L is significantly decreased in ESCC specimens,and its decreased expression is associated with a poor clinical outcome.Overexpression of NEDD4L significantly inhibits cell viability,cell cycle progression,and glutamine metabolism in TE14 cells.Mechanistic study indicates that NEDD4L regulates tumor progression through ubiquitination of c-Myc and modulation of glutamine metabolism.NEDD4L inhibits cell viability,cell cycle progression,and glutamine metabolism in ESCC by ubiquitination of c-Myc to decrease the expressions of GLS1 and SLC1A5.Our findings highlight the importance of NEDD4L/c-Myc signaling in ESCC. | Wei Cheng Guiyuan Li Zhou Ye Jun Hu Lixia Gao Xiaoling Jia Suping Zhao Yan Wang Qin Zhou | 2022 | Acta Biochimica et Biophysica Sinica2022，54，5： | 0 |
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