维普期刊资源整合服务平台（V6.5）

维普中文期刊产品整合服务

16篇 您的检索式：作者名="Suzanne L T"

选中清除导出查看参考文献查看引证文献引用追踪共1页首页上一页第1页下一页末页 /1 跳转

		题名	作者	年代	出处	被引量
	1	Grain size dependency in the occurrence of sand waves显示文摘	Hennie Henri?t Veen Suzanne Jacqueline Marie Hélène Hulscher Michiel Adrianus Frederik Knaapen	2006	Ocean Dynamics (-)2006，，3：	1
	2	Theobroma cacao improves bone growth by modulating defective ciliogenesis in a mouse model of achondroplasia显示文摘A gain-of-function mutation in the fibroblast growth factor receptor 3 gene(FGFR3)results in achondroplasia(ACH),the most frequent form of dwarfism.Constitutive activation of FGFR3 impairs bone formation and elongation and many signal transduction pathways.Identification of new and relevant compounds targeting the FGFR3 signaling pathway is of broad importance for the treatment of ACH,and natural plant compounds are prime drug candidate sources.Here,we found that the phenolic compound(-)-epicatechin,isolated from Theobroma cacao,effectively inhibited FGFR3’s downstream signaling pathways.Transcriptomic analysis in an Fgfr3 mouse model showed that ciliary mRNA expression was modified and influenced significantly by the Indian hedgehog and PKA pathways.(-)-Epicatechin is able to rescue mRNA expression impairments that control both the structural organization of the primary cilium and ciliogenesis-related genes.In femurs isolated from a mouse model(Fgfr3^(Y367C/+))of ACH,we showed that(-)-epicatechin eliminated bone growth impairment during 6 days of ex vivo culture.In vivo,we confirmed that daily subcutaneous injections of(-)-epicatechin to Fgfr3^(Y367C/+) mice increased bone elongation and rescued the primary cilium defects observed in chondrocytes.This modification to the primary cilia promoted the typical columnar arrangement of flat proliferative chondrocytes and thus enhanced bone elongation.The results of the present proof-of-principle study support(-)-epicatechin as a potential drug for the treatment of ACH.	Ludovic Martin Nabil Kaci Catherine Benoist-Lasselin Marine Mondoloni Suzanne Decaudaveine Valentin Estibals Maxence Cornille Léa Loisay Justine Flipo Benoît Demuynck Maria de la Luz Cádiz-Gurrea Florent Barbault Salvador Fernández-Arroyo Laurent Schibler Antonio Segura-Carretero Emilie Dambroise Laurence Legeai-Mallet	2022	Bone Research2022，10，1：	1
	3	Specific release of granulocytemacrophage colony-stimulating factor, tumor necrosis factor-α, and IFN-γby human tumor-infiltrating lymphocytes after autologous tumor stimulation显示文摘	Suzanne L T Marie M	1991	J Immunol1991，146，：	1
	4	Expansion of human tumor infiltrating lymphocytes for use in immunotherapy trials 显示文摘	Linda M M Diane S	1987	J Immunol Methods1987，102，：	1
	5	Electrochemical treatment and HPLC analysis of wastewater containing acid dyes显示文摘	Suzanne M Ann T L	1994	Textile Chemists and Colorists1994，26，4：	1
	6	Passively transferred monoclonal antibody to the M2 protein inhibits influenza A virus replication in mice显示文摘	John J T Eveline L T Suzanne L Z	1990	J Virol1990，34，：	1
	7	Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial显示文摘	George D Demetri Allan T van Oosterom Christopher R Garrett Martin E Blackstein Manisha H Shah Jaap Verweij Grant McArthur Ian R Judson Michael C Heinrich Jeffrey A Morgan Jayesh Desai Christopher D Fletcher Suzanne George Carlo L Bello Xin Huang Charles	2006	The Lancet2006，，9544：	1
	8	Electrochemical Treatment and HPLC analysis of wastewater contaning acid dyes显示文摘	Ann T L	1994	Texile Chemists and Colovists1994，26，4：	1
	9	Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial显示文摘	George D Demetri Allan T van Oosterom Christopher R Garrett Martin E Blackstein Manisha H Shah Jaap Verweij Grant McArthur Ian R Judson Michael C Heinrich Jeffrey A Morgan Jayesh Desai Christopher D Fletcher Suzanne George Carlo L Bello Xin Huang Charles	2006	The Lancet . 2006 (9544)2006，，9544：	1
	10	Bistatic ocean surface reverberation simulation显示文摘	RICHARD L C SUZANNE T M	1991	IEEE Ch2977-9/91/0000-14531991，，：	1
	11	p21(WAF1) gene promoter is epigenetically silenced by CTIP2 and SUV39H1显示文摘	Cherrier T Suzanne S Redel L	2009	Oncogene2009，28，：	1
	12	Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial显示文摘	George D Demetri Allan T van Oosterom Christopher R Garrett Martin E Blackstein Manisha H Shah Jaap Verweij Grant McArthur Ian R Judson Michael C Heinrich Jeffrey A Morgan Jayesh Desai Christopher D Fletcher Suzanne George Carlo L Bello Xin Huang Charles	2006	The Lancet2006，，9544：	1
	13	Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial显示文摘	George D Demetri Allan T van Oosterom Christopher R Garrett Martin E Blackstein Manisha H Shah Jaap Verweij Grant McArthur Ian R Judson Michael C Heinrich Jeffrey A Morgan Jayesh Desai Christopher D Fletcher Suzanne George Carlo L Bello Xin Huang Charles	2006	The Lancet2006，，9544：	1
	14	Primary sulphide melt inclusions in mantle-derived megacrysts显示文摘	Anderson T Griffin W L O'Reilly Suzanne Y	1987	Lithos1987，20，：	1
	15	Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial显示文摘	George D Demetri Allan T van Oosterom Christopher R Garrett Martin E Blackstein Manisha H Shah Jaap Verweij Grant McArthur Ian R Judson Michael C Heinrich Jeffrey A Morgan Jayesh Desai Christopher D Fletcher Suzanne George Carlo L Bello Xin Huang Charles	2006	The Lancet2006，，9544：	1
	16	Aging alters gastric mucosal responses to epidermal growth factor and transforming growth factor-a 显示文摘	JERROLD R T LIU L SUZANNE E G	2000	American Journal of Physiology-Cell Physiology2000，278，5：	1

返回顶部每页显示：

共1页首页上一页第1页下一页末页 /1 跳转

goolge学术搜索-维普

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1　渝公网安备 50019002500403号　违法和不良信息举报中心

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费