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| 1 | 曲马多治疗糖尿病性神经疼痛的双盲随机试验显示文摘目的 :本研究旨在评价曲马多治疗糖尿病性神经痛的有效性和安全性。背景 :糖尿病性神经痛是糖尿病患者的主要症状 ,其治疗和其他的末梢神经病变一样 ,不能令人满意。曲马多是作用于中枢的镇痛剂 ,用于治疗中到重度疼痛。方法 :多中心、门诊病例、随机、双盲、安慰剂做对照、设置平行组的研究 ,包括清洗期 (在此期间停用所有镇痛剂 )和一个为期 42天的双盲治疗期。总共有 1 31名患糖尿病性神经痛的患者按每日 4次接受了曲马多 (n =65)或看上去与曲马多相同的安慰剂胶囊治疗 (n =66)。 42天的治疗结束后或治疗中断后比较曲马多组和安慰剂组平均疼痛强度评分作出主要有效性分析 ;次要有效性分析为疼痛缓解率评分和根据日常活动和睡眠状况作出的对生活质量的评估。结果 :曲马多平均剂量为 2 1 0mg/天 ,治疗糖尿病性神经痛较安慰剂有显著疗效 (P≤ 0 .0 0 1 )。曲马多组患者生理(P =0 .0 2 )和社会功能 (P =0 .0 4 )的评分显著优于安慰剂组。未发现对睡眠有显著治疗作用。曲马多最常见的不良反应是恶心 ,便秘 ,头疼和嗜睡。结论 | Harati Y Gooch C Swenson M Green D Raskin P Donofrio P Cornblath D Sachdeo R Siu CO Kamin M | 2001 | 中国疼痛医学杂志2001，7，1： | 2 |
| 2 | Plant DNA barcodes and a community phylogeny of a tropical forest dynamics plot in Panama 显示文摘 | Kress W J Erickson D L Jones FA Swenson N G Perez R Sanjur 0 Bermingham E | 2009 | PNAS2009，106，18： | 1 |
| 3 | Synthesis and Structures of Mono-and Bis(amidinate)Complexes of Aluminum显示文摘 | Coles M P Swenson D C Jordan R F | 1997 | Organometallics1997，16，： | 1 |
| 4 | Evaluation of serological tests for the detection of pseudorabies gE antibodies during early in- fection 显示文摘 | Kinker D R Swenson S L Wu L L | 1997 | Vet Microbiol1997，55，1234： | 1 |
| 5 | Electron-impact-ionization Cross-section Measurements for Ti11+ and Cr13+ 显示文摘 | Wang L J Swenson D R | 1990 | Phys Rev1990，41，11： | 1 |
| 6 | Genetic reassortment of avian, swine and human influenza virus in American pigs 显示文摘 | Zhou N N Senne D A Landgraf J S Swenson S L Erickson G Rassow K Liu L Yoon K Krauss S Webster R G | 1999 | Virology1999，73，10： | 1 |
| 7 | Fixation of phosphate by iron and aluminum and replacement by organic and inorganic ions 显示文摘 | Swenson R M Cole C V Sieling D H | 1949 | Soil Sci1949，67，： | 1 |
| 8 | Evaluation of serological tests for the detection of pseudorabies gE antibodies during early infection显示文摘 | Kinker D Swenson R S Wu L L | 1997 | Vet Microbiol1997，55，： | 1 |
| 9 | Modeling flow in aJointed geothermal reservoir显示文摘 | DuTeau R Swenson D V | 1994 | Geothermal Resources Council Transactions1994，18，46： | 1 |
| 10 | The performance and carcass composition responses of finishing swine to arange of porcine somatotropin doses in a 1-week delivery system显示文摘 | KNIGHT C D KASSER T R SWENSON G H | 1991 | J Anim Sci1991，69，10： | 1 |
| 11 | Human T cell IgD receptors react with O-glycans on both human IgD and IgA1显示文摘 | Swenson C D Patel T Parekh R B | 1998 | Eur J Immunol1998，28，8： | 1 |
| 12 | Human T cell IgD receptors react with O-glycans on both human IgD and IgA1 显示文摘 | Swenson C D Patel T Parekh R B | 1998 | Eur J Immunol1998，28，8： | 1 |
| 13 | A Coupled Model of Fluid Flowin Jointed Rock Applied to Simu- lation of a Hot Dry Rock Reservoir显示文摘 | Swenson D V DuTeau R Sprecker T | 1997 | International Journal of Rock Mechanics and Mining Sciences1997，34，： | 1 |
| 14 | Influence of depression and effect of treatment with sertraline on quality of life alter hospitalization for acute coronary syn- drome显示文摘 | Swenson J R O'Connor C M Barton D | 2003 | Am J Cardiol2003，92，11： | 1 |
| 15 | Neutral and cationic palladium( II ) bis(pyrazolyl)methane complexes显示文摘 | TSUJI S SWENSON D C JORDAN R F | 1999 | Organometallics1999，18，23： | 1 |
| 16 | Evaluation of serological tests for the detection of pseudorabies gE antibodies during early infection显示文摘 | Kinker D R Swenson S L Wu L L | 1997 | Vet Microbiol1997，55，： | 1 |
| 17 | Malettinin A:a new antifungal tropolone from an unidentified fungal colonist of Hypoxylon stromata(NRRL 29110)显示文摘 | Angawi R F Swenson D C Gloer J B | 2003 | Tetrahedron Lett2003，44，41： | 1 |
| 18 | Evaluation of serological tests for the detection of pseudorabies gE antibodies during early infection显示文摘 | Kinker D R Swenson S L Wu L L | 1997 | Vet Microbiol1997，55，14： | 1 |
| 19 | Early extubation after cardiac surgery using combined intrathecal sufentanil and morphine显示文摘 | Swenson J D Hullander R M Wingler K | 1994 | J Cardiothorac Vasc Anesth1994，8，5： | 1 |
| 20 | Synthesis and structure of 2,5,8-triazido-s-heptazine: an energetic and luminescent precursor to nitrogen-rich carbon nitrides显示文摘 | Miller D R Swenson D C Gillan E G | 2004 | J Am Chem Soc2004，126，17： | 1 |
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