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| 1 | Diffusion-weighted magnetic resonance imaging to predict response of hepatocellular carcinoma to chemoembolization显示文摘AIM: To investigate whether intra-procedural diffusion- weighted magnetic resonance imaging can predict response of hepatocellular carcinoma (HCC) during trans- catheter arterial chemoembolization (TACE). METHODS: Sixteen patients (15 male), aged 59 ±11 years (range: 42-81 years) underwent a total of 21 separate treatments for unresectable HCC in a hybrid magnetic resonance/interventional radiology suite. Ana- tomical imaging and diffusion-weighted imaging (b = 0, 500 s/mm2) were performed on a 1.5-T unit. Tumor enhancement and apparent diffusion coefficient (ADC, mm2/s) values were assessed immediately before and at 1 and 3 mo after TACE. We calculated the percent change (PC) in ADC values at all time points. We compared follow-up ADC values to baseline values using a paired t test (α = 0.05). RESULTS: The intra-procedural sensitivity, specificity, and positive and negative predictive values (%) for detecting a complete or partial 1-mo tumor response using ADC PC thresholds of ±5%, ±10%, and ±15% were 77, 67, 91, and 40; 54, 67, 88, and 25; and 46, 100, 100, and 30, respectively. There was no clear predictive value for the 3-mo follow-up. Compared to baseline, the immediate post-procedure and 1-mo mean ADC values both increased; the latter obtaining statistical significance (1.48 ± 0.29 mm2/s vs 1.65 ± 0.35 × 10-3 mm2/s, P < 0.014). CONCLUSION: Intra-procedural ADC changes of > 15% predicted 1-mo anatomical HCC response with the greatest accuracy, and can provide valuable feedback at the time of TACE. | Johnathan C Chung Neel K Naik Robert J Lewandowski Mary F Mulcahy Laura M Kulik Kent T Sato Robert K Ryu Riad Salem Andrew C Larson Reed A Omary | 2010 | World Journal of Gastroenterology2010，16，25： | 13 |
| 2 | Gastroenteropancreatic neuroendocrine tumours显示文摘 | Irvin M Modlin Kjell Oberg Daniel C Chung Robert T Jensen Wouter W de Herder Rajesh V Thakker Martyn Caplin Gianfranco Delle Fave Greg A Kaltsas Eric P Krenning Steven F Moss Ola Nilsson Guido Rindi Ramon Salazar Philippe Ruszniewski Anders Sundin | 2008 | Lancet Oncology2008，，1： | 8 |
| 3 | Excited - state properties of dioxorhenium(V) generation and reactivity of dioxorhenium(Ⅵ) 显示文摘 | Che C M Chung W C Lai T F | 1989 | Inorg Chem1989，28，： | 1 |
| 4 | Transvaginal sonography and theconservative management of spontaneous abortion 显示文摘 | Haines C J Chung T Leung DY | 1994 | Gyneeol Obstet Invest1994，37，1： | 1 |
| 5 | Effects of insulin replacement on cardiac apoptotic and survival pathways in streptozotocin-induced diabetic rats显示文摘 | Kuo W W Chung L C Liu C T | 2009 | Cell Biochem Funct2009，27，7： | 1 |
| 6 | Genetic diversity and biogeography of Cunninghamia konishii ( Cupressaeeae ) , an island species in Taiwan:a comparison with Cunninghamia lanceolata, a mainland species in China显示文摘 | Chung J D Lin T P Tan Y C | 2004 | Molecular Phy- logeneties and Evolution2004，33，： | 1 |
| 7 | Business Process Management: Survey and Methodology显示文摘 | Elzinga D J Horak T Chung - Yee L Bruner C | 1995 | IEEE Transactions on Engineering Management1995，24，2： | 1 |
| 8 | Synthesis of PP graft copolymers via anionic living graft-from reactions of polypropylene containing reactive p-methylstyrene Units 显示文摘 | Lu H L Chung T C | 1999 | J Polym Sci Part A:Polym Chem1999，37，22： | 1 |
| 9 | Probabilistic eigenvalue sensitivity indices for robust PSS site selection显示文摘 | Wang K W Chung C Y Tse C T | 2001 | IEE Proceedings-Generation Transmission and Distribution2001，148，6： | 1 |
| 10 | Gelation of surimi by high hydrostatic pressure显示文摘 | Chung Y C Gebrehiwot A Farkas D F Morrissey M T | 1994 | J Food Sci1994，59，52： | 1 |
| 11 | Power-System Stabi- lizer(PSS) design by Probabilistic Sensitivity Indexes (PSIs) 显示文摘 | CHUNG C Y WANG K W TSE C T | 2002 | IEEE Trans on Power Systems2002，17，3： | 1 |
| 12 | Growth of Alpha-Hg I2Single Crystals from Physical Vapor Transport in an Oil-bath Furnace显示文摘 | Zhou H T Lee C H Chung J M | 2003 | Materials Research Bulletin2003，38，15： | 1 |
| 13 | Directconverison of cellulose into polyols or H2 over P t/N a (H )-Z S M -5 显示文摘 | YOU S J BEAK I G KIM Y T JEONG K E CHAE H J KIM T W KIM C U KIM T J CHUNG Y M OH S H PARK E D | | Korean J Chem Eng0，28，3： | 1 |
| 14 | Airway gene transfer using cationic emulsion as a mucosal gene carrier显示文摘 | Kim T W Chung H Kwon I C | 2005 | J Gene Med2005，7，6： | 1 |
| 15 | An index of patient reported out- comes (PRO-index) discriminates effectively between active and control treatment in 4 clinical trials of adalimumab in rheumatoid arthritis显示文摘 | Pincus T Chung C Segurado OG | 2006 | J Rheumato12006，33，11： | 1 |
| 16 | Diaehronous uplift of the Tibetan Plateau starting 40 Myr ago显示文摘 | Chung S L Lo C H Lee T Y | 1998 | Nature1998，394，： | 1 |
| 17 | Parameter optimistion of robust power system stabilisters by probabilistic approach显示文摘 | Tse C T Wang K W Chung C Y | 2000 | IEE Proceedings-Generation Transmission and Distribution2000，147，2： | 1 |
| 18 | Imaging and surgical re-pair of a bifurcating aortico-left ventricle tunnel显示文摘 | Kaiser C A Chung T Rosenfeld H M | 2011 | Ann Thorac Surg2011，91，2： | 1 |
| 19 | Effect of Si/Ta and nitrogen rati- os on the thermal stability of Ta-Si-N thin films显示文摘 | Chung C K Chen T S | 2010 | Mi- croelectronic Engineering2010，87，： | 1 |
| 20 | Double-skinned forward osmosis membranes for reducing internal concentration po- larization within the porous sublayer显示文摘 | Wang K Y Ong R C Chung T S | 2010 | Industrial and En- gineering Chemistry Research2010，49，10： | 1 |
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