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| 1 | Surface‑Enhanced Raman Scattering Fiber Probe Based on Silver Nanocubes显示文摘Surface-enhanced Raman scattering(SERS)provides a novel method for low concentration molecular detection.The performances were highly dependent on the sizes,geometries and distributions of metal nanostructures.Here,highly sensitive SERS fber probe based on silver nanocubes(Ag NCs)was fabricated,by assembled nanostructures on planar and tapered fber tips.Ag NCs were synthesized by polyol method,and controlled by reductant content,reaction temperatures and crystal growth durations.Tapered fbers with diferent cone angles were prepared by chemical etching.The electromagnetic distribution simulation indicated that nanocubes had stronger electric feld between two cubes and vertex corners than nanosphere,under 532 nm laser excitation.The intensity could reach 53.52 V/m,for cubes with 70 nm edge length.The SERS performance of probes was characterized using crystal violet analyte.The detectable lowest concentration could reach 10^(-9) and 10^(-10) M for planar and tapered fber probes,respectively.The corresponding enhancement factor could be 9.02×10^(7) and 6.22×10^(8).The relationship between SERS peak intensities and analyte concentrations showed well linear,which indicated both fber probes could be applied for both qualitative and quantitative analysis.Furthermore,optimal cone angle of tapered fber SERS probe was 8.3°.The tapered fber SERS probes have highly sensitive activity and great potential in substance detection. | Miao Yu Qihang Tian Guangyuan He Kaimin Cui Jihong Zhang | 2021 | Advanced Fiber Materials2021,3,6: | 3 |
| 2 | VEGF-B prevents excessive angiogenesis by inhibiting FGF2/FGFR1 pathway显示文摘Although VEGF-B was discovered as a VEGF-A homolog a long time ago,the angiogenic effect of VEGF-B remains poorly understood with limited and diverse findings from different groups.Notwithstanding,drugs that inhibit VEGF-B together with other VEGF family members are being used to treat patients with various neovascular diseases.It is therefore critical to have a better understanding of the angiogenic effect of VEGF-B and the underlying mechanisms.Using comprehensive in vitro and in vivo methods and models,we reveal here for the first time an unexpected and surprising function of VEGF-B as an endogenous inhibitor of angiogenesis by inhibiting the FGF2/FGFR1 pathway when the latter is abundantly expressed.Mechanistically,we unveil that VEGF-B binds to FGFR1,induces FGFR1/VEGFR1 complex formation,and suppresses FGF2-induced Erk activation,and inhibits FGF2-driven angiogenesis and tumor growth.Our work uncovers a previously unrecognized novel function of VEGF-B in tethering the FGF2/FGFR1 pathway.Given the anti-angiogenic nature of VEGF-B under conditions of high FGF2/FGFR1 levels,caution is warranted when modulating VEGF-B activity to treat neovascular diseases. | Chunsik Lee Rongyuan Chen Guangli Sun Xialin Liu Xianchai Lin Chang He Liying Xing Lixian Liu Lasse DJensen Anil Kumar Harald FLanger Xiangrong Ren Jianing Zhang Lijuan Huang Xiangke Yin JongKyong Kim Juanhua Zhu Guanqun Huang Jiani Li Weiwei Lu Wei Chen Juanxi Liu Jiaxin Hu Qihang Sun Weisi Lu Lekun Fang Shasha Wang Haiqing Kuang Yihan Zhang Geng Tian Jia Mi Bi-Ang Kang Masashi Narazaki Aaron Prodeus Luc Schoonjans David MOrnitz Jean Gariepy Guy Eelen Mieke Dewerchin Yunlong Yang Jing-Song Ou Antonio Mora Jin Yao Chen Zhao Yizhi Liu Peter Carmeliet Yihai Cao Xuri Li | 2023 | Signal Transduction and Targeted Therapy2023,8,9: | 0 |
| 3 | The Evaluation of Educational Literacy of Physics Students in Normal Universities Under China’s Professional Certification System显示文摘This article discusses the connotation of the evaluation of educational literacy of physics students in normal universities,provides the evaluation criteria for students’teaching ability,improves the evaluation composition of educational literacy of physics students in normal universities,and provides the score distribution of the 10 items in educational literacy,in hope to improve the training quality of university students. | Zujun Li Qihang Zhou Shiwen Ni Tian Liang Xingyao Han | 2022 | Journal of Contemporary Educational Research2022,6,1: | 0 |
| 4 | The Fabrication and SERS Performance of Multi-layer Hollow Au-Ag Alloy Nano Urchins Structure-based SERS Fiber Probe显示文摘Novel hollow Au Ag alloy nano urchins were synthesized via Ag seeds growth method,and self-assembly coated on the wall and end-tip of silica fiber for fiber probe fabrication.The nano urchins homogeneously distributed on fiber surface because of fiber silanization.The sizes and tip sharpness of the nano-urchins could be controlled by Ag seeds.The elements distribution analysis indicated there was high Ag content in tip-top for better surface enhance Raman scattering performance.The detectable concentration could be as low as 10-8 M using crystal violet molecules as analyte.Moreover,the fiber probes were stable in air,due to Au in the alloy.This fiber probe could be used for low content single molecular analysis. | HAO Zhenbang TIAN Qihang CAO Shiyi HAN Xiaoyu ZHANG Jihong XIE Jun ZHAO Xiujian | 2023 | Journal of Wuhan University of Technology(Materials Science)2023,38,2: | 0 |
| 5 | The Distribution of Relative Light Intensity in a Peach Tree Canopy Affects Fruit Yield and Texture显示文摘Light is crucial to the uniform production of high-quality fruit since it is the driving force for leaf photosynthesis and hence overall plant nutrition.The objective of this study was to evaluate the relationship between the distribution of relative light intensity in the peach tree(Prunus persica)canopy and the yield and texture of peach fruits.The canopy of 7-year-old‘Qiuyan’was divided into cubical volumes and the relative light intensity distribution was measured for each cube,along with yield distribution and fruit textural properties at different growing times.The relative light intensity decreased gradually from outside to inside the canopy and from top to bottom.The yield distribution and the relative light intensity were clearly correlated.The percentage of the canopy receiving<30%relative light intensity was 49.07%in May,56.02%in June,and 58.95%in July,whereas the percentage receiving>80%relative light intensity was 32.72%,17.28%,and 10.96%,respectively.Consistent with this,peaches were found in the upper and middle portions of the canopy,within 1.5-3.0 m of the top.The regression equation showed that fruit texture index correlated significantly with relative light intensity.Relative light intensity is the main factor affecting peach yield and texture and must be above 41.83%for good peach quality.Orchardists should carefully plan summer pruning strategies to adjust the number and spatial distribution of branches accordingly. | Zhaoyuan WANG Qihang TIAN Yong GUO Ruifeng CHANG Guojian LIU Hu CHEN Yonghong LI | 2021 | Agricultural Biotechnology2021,10,3: | 0 |
| 6 | Ultra-small PbSe Quantum Dots Synthesis by Chemical Nucleation Controlling显示文摘Ultra-small PbSe quantum dots (QDs) were synthesized using conventional hot-injection method.A small amount of Sn was used as a nucleation promotion agent to control nucleation and growth during the QDs synthesis process.The average diameter of the QDs is about 1.6 nm,of which absorption peak centers at 550 nm and photoluminescence peak centers at 750 nm under 350 nm laser excitation with power as low as 500 μW.Transmission electron microscopy images confirm that the QDs size well matches with the calculated diameter from Brus equation.This match and electron energy loss spectroscopy analysis proves that Sn is not involved into the final structure of the ultra-small PbSe QDs.An ion-exchange process was proposed for the nucleation control and ultra-small QDs synthesis.The prepared ultra-small QDs could be a promising candidate for luminescence,solar cell devices,and others. | 程方亮 YU Miao JIA Linyuan TIAN Qihang 张继红 Bokhyeon Kim ZHAO Xiujian | 2021 | Journal of Wuhan University of Technology(Materials Science)2021,36,4: | 0 |
| 7 | Upconversion and Near Infrared Emission of Rare Earth Ions in Chalcohalide Glass at the Early Stage of Crystallization显示文摘Nd^(3+),Er^(3+)ions doped 0.9(Ge_(0.25)Ga_(0.10)S_(0.65))-0.1CsBr chalcohalide glass were prepared via melt-quenching method,and heat treated at 360℃ in high purity Ar gas atmosphere for different hours for the early stage of crystallization.The effect of heat treatment durations on visible upconversion luminescence and near infrared emission from Nd^(3+)ions and Er^(3+)ions were investigated.The specimens kept amorphous status until the heat treatment duration extended to 10 hours,for Ga_(2)S_(3) nano-crystal formation in glass matrix.The stark splitting in visible upconversion luminescence center at 600 nm from Nd^(3+)ions weakened,and disappeared,and the shape of infrared emission centered at 1550 nm from Er^(3+)ions changed,with the heat treatment duration increased.The lifetime of Nd^(3+):^(4)F_(3/2) level and Er^(3+):^(4)I_(13/2) level dropped,then increased with heat treatment duration increased.X-ray diffraction patterns and transmission electron microscope images confirmed the amorphous state and Ga_(2)S_(3) nano-crystals formation in glass matrix.The rare earth ions local environment changes with heat treatment duration were proposed,based on the emission and lifetime changes.This research will be helpful for the understanding of rare earth doped chalcohalide crystallization mechanism and processes. | 余淼 CUI Kaimin TIAN Qihang HE Guangyuan XIE Jun 张继红 | 2022 | Journal of Wuhan University of Technology(Materials Science)2022,37,4: | 0 |