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| 1 | BMP-6 inhibits microRNA-21 expression in breast cancer through repressing 6EF1 and AP-1显示文摘 | Jun Du Shuang Yang Di An Fen Hu Wei Yuan Chunli Zhai Tianhui Zhu | 2009 | Cell Research2009，19，4： | 44 |
| 2 | Occurrence, spatial distribution and ecological risks of antibiotics in soil in urban agglomeration显示文摘Antibiotics in soil environment are regarded as emerging pollutants and have introduced increasing risks to soil ecosystem and human health in rapid urbanization areas. Identifying the occurrence and spatial variability of antibiotics in soils is an urgent issue in sustaining soil security. In this study, antibiotics in soils were investigated and analyzed in BeijingTianjin-Hebei urban agglomeration. The occurrence, spatial distribution, and related affecting factors of antibiotics in soils were identified and ecological risks of antibiotics in soil environment were assessed. Results showed that(1) The mean concentration of soil antibiotics in Beijing-Tianjin-Hebei urban agglomeration was 21.79 μg/kg. Land use substantially affected the occurrence and concentration of antibiotics in soils. Concentrations of antibiotics in cropland and orchard soils were 2-3 times higher than the other land use types.(2)The concentrations of antibiotics in soils in Beijing-Tianjin-Hebei urban agglomeration presented a spatial pattern of high values in southeast, and low values in northwest. Spatial variability of antibiotics in soils was closely related to the application of organic fertilizer and wastewater irrigation as well as topographical features. Furthermore, soil properties and land management policy had substantial influences on soil antibiotics, and soil heavy metals may aggravate the accumulation of antibiotics in soils.(3) Ecological risks assessment of antibiotics in soils demonstrated that erythromycin(ERY), sulfamethoxazole(SMX), and doxycycline(DOX) may introduce high risks to soil ecosystem health, and more attention should be paid to the areas with intensive human activities that had potential high risk to soil ecosystem health. This study suggests that scientific land and soil management should be considered to prevent soil antibiotic pollution and sustain soil security in urban agglomeration. | Min Li Lei Yang Haw Yen Fangkai Zhao Xinmiao Wang Tianhui Zhou Qingyu Feng Liding Chen | 2023 | Journal of Environmental Sciences2023，，3： | 5 |
| 3 | Inhibition of gasdermin D-dependent pyroptosis attenuates the progression of silica-induced pulmonary inflammation and fibrosis显示文摘Silicosis is a leading cause of occupational disease-related morbidity and mortality worldwide,but the molecular basis underlying its development remains unclear.An accumulating body of evidence supports gasdermin D(GSDMD)-mediated pyroptosis as a key component in the development of various pulmonary diseases.However,there is little experimental evidence connecting silicosis and GSDMD-driven pyroptosis.In this work,we investigated the role of GSDMD-mediated pyroptosis in silicosis.Single-cell RNA sequencing of healthy and silicosis human and murine lung tissues indicated that GSDMD-induced pyroptosis in macrophages was relevant to silicosis progression.Through microscopy we then observed morphological alterations of pyroptosis in macrophages treated with silica.Measurement of interleukin-1βrelease,lactic dehydrogenase activity,and real-time propidium iodide staining further revealed that silica induced pyroptosis of macrophages.Additionally,we verified that both canonical(caspase-1-mediated)and non-canonical(caspase-4/5/11-mediated)signaling pathways mediated silica-induced pyroptosis activation,in vivo and in vitro.Notably,Gsdmd knockout mice exhibited dramatically alleviated silicosis phenotypes,which highlighted the pivotal role of pyroptosis in this disease.Taken together,our results demonstrated that macrophages underwent GSDMD-dependent pyroptosis in silicosis and inhibition of this process could serve as a viable clinical strategy for mitigating silicosis. | Meiyue Song Jiaxin Wang Youliang Sun Junling Pang Xiaona Li Yuan Liu Yitian Zhou Peiran Yang Tianhui Fan Ying Liu Zhaoguo Li Xianmei Qi Baicun Li Xinri Zhang Jing Wang Chen Wang | 2022 | Acta Pharmaceutica Sinica B2022，12，3： | 5 |
| 4 | Safety and effectiveness of Traditional Chinese Medicinal herbs for diabetic foot:a systematic review and Meta-analysis显示文摘OBJECTIVE: To evaluate the safety and effectiveness of traditional Chinese medicinal herbs(TCMHs) as an adjunctive treatment for diabetic foot(DF).METHODS: The sources used were Pub Med(1966 to August 2015), the Cochrane Library(1988 to August 2015), the Excerpta Medica Database(1974 to August 2015), Wiley(1807 to August 2015), Ovid(1988 to August 2015), Clinical Trials.gov(1993 to August 2015), the Cochrane Central Register of Controlled Trials(1966 to August 2015), China Science and Technology Journal Database(1994 to August2015), Chi CTR(2007 to August 2015), Sino Med(1978 to August 2015), the China National Knowledge Infrastructure(1984 to August 2015), Wanfang Data Knowledge Service Platform(1998 to August 2015), and the Traditional Chinese Medical Literature Analysis and Retrieval System(TCMLARS)(1984 to August 2015). Studies were identified and selected, and the data were extracted by two independent reviewers. The Cochrane Risk of Bias tool was used to assess the quality of studies. Revman 5.2 software was used for data synthesis and analysis.RESULTS: Sixteen studies were included based on the selection criteria. Of these, seven studies had low bias risk and one had high bias risk. In the overall analysis, TCMHs resulted in a significantly higher total effective rate(OR 5.08; 95% CI 3.50 to7.36; P < 0.000 01), cure rate(OR 2.12; 95% CI1.63 to 2.77; P < 0.000 01), and shorter time to ulcer healing(SMD-0.64; 95% CI-0.89 to-0.40;P < 0.000 01) when compared with non-TCMHs treated DF. The analysis also revealed that significantly fewer amputations occurred in TCMHs patients(OR 0.36; 95% CI 0.20 to 0.65; P = 0.0007).Sensitivity analysis indicated that the findings of the Meta-analysis were robust to study quality,and the funnel plot of the Egger test showed no publication bias.CONCLUSION: TCMHs intervention appears to be more effective for DF, with a similar safety profile,when compared with non-TCMHs treatments, although this result requires further verification with more well-designed studies. | Chen Shuo Ma Jianwei Xu Limei Niu Tianhui Dong Jing Liu Wenjun Han Qi | 2017 | Journal of Traditional Chinese Medicine2017，37，6： | 5 |
| 5 | Collaborative supply chain planning under dynamic lot sizing costs with capacity decision显示文摘Studies show that supply chain cooperation improves supply chain performance. However, it remains a challenge to develop and implement the realistic supply chain cooperation scheme. We investigate a two-echelon supply chain planning problem with capacity acquisition decision under asymmetric cost and demand information. A simple negotiation-based coordination mechanism is developed to synchronize production/order strategies of a supplier and a buyer. The coordination scheme shows how the supplier and the buyer modify their production and order policy in order to find a joint economic lot sizing plan, which saves the overall supply chain cost. The allocation of the cooperation benefit is determined by negotiation. Due to the complexity of the multiple periods, multiple level supply chain lot sizing with capacity decision, a heuristic algorithm is developed to find coordination solutions. Finally, the results of the numerical study indicate the performance of supply chain coordination scheme. | Hongyan Li Tianhui You Xiaoyi Luo | 2011 | Journal of Systems Engineering and Electronics2011，22，2： | 3 |
| 6 | Downregulation of circ-ZNF609 Promotes Heart Repair by Modulating RNA N^(6)-Methyladenosine-Modified Yap Expression显示文摘Circular RNAs take crucial roles in several pathophysiological processes.The regulatory role and its underlying mechanisms of circ-ZNF609 in the heart remains largely unknown.Here,we report that circ-ZNF609 is upregulated during myocardial ischemia/reperfusion(I/R)remodeling.Knockdown of circ-ZNF609 protects against acute I/R injury and attenuates left ventricle dysfunction after I/R remodeling in vivo.In vitro,circ-ZNF609 regulates cardiomyocyte survival and proliferation via modulating the crosstalk between Hippo-YAP and Akt signaling.Mechanically,N6-methyladenosine-modification is involved in the regulatory role of circ-ZNF609 on YAP.An in-depth study indicates that knockdown of circ-ZNF609 decreases the expression of YTHDF3 and further fine-tuned the accessibility of Yap mRNA to YTHDF1 and YTHDF2 to regulate YAP expression.circ-ZNF609 knockdown represents a promising therapeutic strategy to combat the pathological process of myocardial I/R injury. | Lijun Wang Pujiao Yu Jiaqi Wang Guie Xu Tianhui Wang Jingyi Feng Yihua Bei Jiahong Xu Hongbao Wang Saumya Das Junjie Xiao | 2022 | Research2022，，3： | 3 |
| 7 | Enhancing oxygen evolution reaction by cationic surfactants显示文摘Oxygen evolution reaction is critical for water splitting or metal-air batteries,but previous research mainly focuses on electrode material or structure optimization.Herein,we demonstrate that surfactant modification of a NiFe layered double hydroxide (LDH) array electrode,one of the best catalysts for oxygen evolution reaction (OER),could achieve superaerophobic surface with balanced surface charges,affording fast mass transfer,quick gas release,and boosted OER performance.The assembled surfactants on the electrode surface are responsible for lowering the bubble adhesive force (~ 1.03 μN) and corresponding fast release of small bubbles generated during OER.In addition,the bipolar nature of the hexadecyl trimethyl ammonium bromide (CTAB) molecule lead to bilayer assembly of the surfactants with the polar ends facing the electrode surface and the electrolyte,resulting in neutralized charges on the electrode surface.As a result,OH-transfer was facilitated and OER performance was enhanced.With the modified superaerophobic surface and balanced surface charge,NiFe LDHs-CTAB nanostructured electrode showed ultrahigh current density increase (9.39 mA(mV·cm^2)),2.3 times higher than that for conventional NiFe LDH nanoarray electrode),dramatically fast gas release,and excellent durability.The introduction of surfactants to construct under-water superaerophobic electrode with in-time repelling ability to the as-formed gas bubbles may open up a new pathway for designing efficient electrodes for gas evolution systems with potentially practical application in the near future. | Qixian Xie Daojin Zhou Pengsong Li Zhao Cai Tianhui Xie Tengfei Gao Ruida Chen Yun Kuang Xiaoming Sun | 2019 | Nano Research2019，12，9： | 3 |
| 8 | A potential approach to replace sulfurized olefins with borate ester containing xanthate group in lubricating oil显示文摘To develop a potential substitute for sulfurized olefins, a borate ester derivative containing xanthate group (titled BXT) was synthesized and characterized. Meanwhile, its tribological properties in rape-seed oil were evaluated using four-ball tribometer. The results indicate that BXT shows excellent tri-bological capacity such as load-carrying, friction-reducing and antiwear property. Moreover, the syn-thesized compound has no noticeable odor, shows little corrosion to copper, and exhibits better ther-mal stability compared with sulfurized olefins. In order to study the action mechanism of BXT in friction process, analysis of the worn surface was carried out using a three-dimensional non-contact surface profilometer and XPS analyzer. | WANG YongGang LI JiuSheng REN TianHui | 2008 | Chinese Science Bulletin2008，53，7： | 3 |
| 9 | On stress-forecasting strategy of earthquakes from stress buildup,stress shadow and stress transfer(SSS) based on numerical approach显示文摘Global Positioning System(GPS) and Interferometric Synthetic Aperture Radar(InSAR),used for monitoring crust deformation,are found to be very promising in earthquake prediction subject to stress-forecasting.However,it is recognized that unless we can give reasonable explanations of these curious precursory phenomena that continue to be seren-dipitously observed from time to time,such high technology of GPS or InSAR is difficult to be efficiently used.Therefore,a proper model revealing the relation between earthquake evolution and stress variation,such as the phenomena of stress buildup,stress shadow and stress transfer(SSS),is crucial to the GPS or InSAR based earthquake prediction.Here we address this question through a numerical approach of earthquake development using an intuitive physical model with a map-like configuration of discontinuous fault system.The simulation provides a physical basis for the principle of stress-forecasting of earthquakes based on SSS and for the application of GPS or InSAR in earthquake prediction.The observed SSS associated phenomena with images of stress distribution during the failure process can be continuously simulated.It is shown that the SSS are better indicators of earthquake precursors than that of seismic foreshocks,suggesting a predict-ability of earthquakes based on stress-forecasting strategy. | Chunan Tang Tianhui Ma Xiaoli Ding | 2009 | Earthquake Science2009，22，1： | 3 |
| 10 | AN ASSIGNMENT METHOD FOR GROUP DECISION MAKING WITH UNCERTAIN PREFERENCE ORDINALS显示文摘This paper presents an assignment method to solve the group decision making problem with uncertain preference information. The uncertain preference information is given as uncertain preference ordinals by decision makers. We first address the concept and calculation formulae of preference ordinal frequency, and then, uncertain preference ordinals are transformed into preference ordinal frequencies accordingly. Furthermore, a linear assignment model is built based on the derived preference ordinal frequencies, and the ranking of alternatives can be obtained by solving the model. Finally, a numerical example is used to illustrate the use of the proposed method. | Tianhui YOU Zhiping FAN Zhuchao YU | 2012 | Journal of Systems Science and Systems Engineering2012，21，2： | 3 |
| 11 | Intense single-band red upconversion emission in BiOCl:Er3+ layered semiconductor via co-doping Ho3+显示文摘Exploring a new tuning way to facilely realize single-band red emission in trivalent rare-earth ions(RE3+) doped upconversion(UC) materials is still desirable.In this work,the intense single-band red emission is achieved by co-doping only Ho3+in the BiOCl:Er3+ under 1550 nm excitation.In the BiOCl layered host,co-doping Ho3+can further enhance the red emission and simultaneously suppress the green emission of Er3+,and thus obviously improve the red-to-green(R/G) ratio.It is found that Ho3+does not se rve as ene rgy trapping through the 5 I6 state as in traditional UC materials but acts as ET bridge(4 S3/2,2 H11/2(Er3+)→5 F4,5 S2(Ho3+)→4 F9/2(Er3+)).The tuning mechanism of Ho3+is discussed in detail and further confirms through a comparative experiment.Our research gives an unusual perspective to tune the UC behavior of Er3+through co-doping Ho3+,which might be inspiring for achievement of single-band red UC emission. | Yuehong Peng Jincai Peng Jiajun Han Tianhui Wang Zhaoyi Yin Jianbei Qiu Qi W ang Zhengwen Yang Zhiguo Song | 2020 | Journal of Rare Earths2020，38，6： | 2 |
| 12 | Synthesis of polypeptide bearing 1,4-dithiane pendants for ROS-responsive drug release显示文摘Stimuli-re sponsive polypeptides have been intensively investigated fo r controlled drug release,owing to their favorable biocompatibility and biodegradability.In this work,we designed and synthesized a new kind of polypeptide bearing 1,4-dithiane pendants for reactive oxygen species(ROS)-responsive drug release.The polypeptide-based block copolymer was facilely synthesized by ring-opening polymerization(ROP)of 1,4-dithian-substituted L-glutamate N-carboxyanhydride(DTG-NCA)monomer using an amino-terminated poly(ethylene glycol)methyl ether(mPEG-NH2)as the macro molecular initiator.The resulta nt block copolyme r,mPEG-b-PDTG,could self-assemble into unifo rm micelles in aqueous medium owing to its amphiphilic structure.Then,the H2 O2-triggered oxidation behaviors of the mPEG-b-PDTG micelles were studied by dynamic light scattering(DLS),FT-IR and turbidimetric assay.It was revealed that the oxidation of thioether into sulfoxide in the side chains would result in disassembly of the micelles.Furthermore,the ROS-responsive drug release behavior of the mPEG-b-PDTG micelles was verified by using Nile Red as a model drug.MTT assay also proved that mPEG-b-PDTG was non-toxic in B16 F10 and L929 cells.Therefore,such a new class of oxidation-responsive polypeptide might provide a promising platform for ROS-responsive drug delivery. | Tianhui Zhang Jiuxu Yao Jiamei Tian Mingxiao Deng Xiuli Zhuang Chunsheng Xiao | 2020 | Chinese Chemical Letters2020，31，5： | 2 |
| 13 | Numerical Integration Over Implicitly Defined Domains with Topological Guarantee显示文摘Numerical integration over the implicitly defined domains is challenging due to topological variances of implicit functions.In this paper,we use interval arithmetic to identify the boundary of the integration domain exactly,thus getting the correct topology of the domain.Furthermore,a geometry-based local error estimate is explored to guide the hierarchical subdivision and save the computation cost.Numerical experiments are presented to demonstrate the accuracy and the potential of the proposed method. | Tianhui Yang Ammar Qarariyah Hongmei Kang Jiansong Deng | 2019 | Communications in Mathematics and Statistics2019，7，4： | 2 |
| 14 | Six-dimensional potential energy surface of the dissociative chemisorption of HCl on Au(111) using neural networks显示文摘We constructed a six-dimensional potential energy surface(PES)for the dissociative chemisorption of HCl on Au(111)using the neural networks method based on roughly 70000 energies obtained from extensive density functional theory(DFT)calculations.The resulting PES is accurate and smooth,based on the small fitting errors and good agreement between the fitted PES and the direct DFT calculations.Time-dependent wave packet calculations show that the potential energy surface is very well converged with respect to the number of DFT data points,as well as to the fitting process.The dissociation probabilities of HCl initially in the ground rovibrational state from six-dimensional quantum dynamical calculations are quite diferent from the four-dimensional fixed-site calculations,indicating it is essential to perform full-dimensional quantum dynamical studies for the title molecule-surface interaction system. | LIU TianHui FU BiNa ZHANG Dong H | 2014 | Science China Chemistry2014，57，1： | 2 |
| 15 | Advanced lanthanide doped upconversion nanomaterials for lasing emission显示文摘Microlasers are narrow-band and coherent light from small cavities,which have been widely applied in biomedicine,optical interconnection,integration devices,etc.Lanthanide doped upconversion materials are potential gain media for microlasers from near infrared(NIR)to visible and UV regimes due to their multi ladder-like metastable energy levels and superior optical frequency conversion capability.The optical feedback from photon scattering of the porous upconversion nanoparticles clusters has been reported to produce upconversion random lasers.The light bouncing back and forth between two reflective surfaces or internal surface has been utilized to achieve modulated upconversion lasing emission.In addition,photon lattices and plasmonic cavities with enhanced electromagnetic fields can amplify the upconversion process within the sub-diffraction volumes and produce highly efficient upconverting lasers.In this review,the recent advances on using lanthanide doped upconversion materials for random,whispering gallery mode(WGM)/Fabry-Perot(FP)cavity and photon lattice/plasmonic cavity modulated upconversion microlasers are overviewed.Current challenges and future directions of the upconverting lasers are also discussed. | Yunfei Shang Tong Chen Tianhui Ma Shuwei Hao Weiqiang Lv Dechang Jia Chunhui Yang | 2022 | Journal of Rare Earths2022，40，5： | 2 |
| 16 | Tribological Evaluation of S-(1H-Benzo-Triazole-1-yl) Methyl N,N-Dialkyldithiocarbamates as Additives in Rapeseed Oil显示文摘 | Jiusheng L Yanyan Z Tianhui R | 2002 | Wear2002，253，： | 1 |
| 17 | Hydrological simulation by SWAT model with fixed and varied parameterization approaches under land use change显示文摘 | Du Jinkang Rui Hanyi Zuo Tianhui | 2013 | Water Resour Manage2013，，27： | 1 |
| 18 | The Ribological Properties of S-(1H-Benzotriazol-1-YL)Methyl Alkyl Xanthates as Additive in Synthetic Lubricants显示文摘 | Tianhui R Qunji X Hanqing W | 1995 | Lubrication Engineering1995，51，10： | 1 |
| 19 | The Tribochemical Study of Some N-Containing Heterocyclic Compounds as Lubricating Oil Additives显示文摘 | Zhongyi He Wenqi Rao Tianhui Ren Weimin Liu Qunji Xue | 2002 | Tribology Letters2002，，2： | 1 |
| 20 | A Study of S-(1H-Benzotriazol-l-yl)Methyl,O,O-Dialkyldithiophosphates as Additives in Liquid Paraff in显示文摘 | Tianhui R Xunji X Hanqing W | 1994 | Wear1994，173，： | 1 |
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