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	题名	作者	年代	出处	被引量
1	Evaluation of the California mastitls test as a precalving treatment selection tool for Holstein heifers显示文摘	Roy J P Du Tremblay D Descoteaux L	2009	Vet Microbiol2009，134，12：	1
2	Loss of T-cell protein tyrosine phosphatase in the intestinal epithelium promotes local inflammation by increasing colonic stem cell proliferation显示文摘T-cell protein tyrosine phosphatase(TC-PTP)has a critical role in the development of the immune system and has been identified as a negative regulator of inflammation.Single-nucleotide polymorphisms in the TC-PTP locus have been associated with increased susceptibility to inflammatory bowel diseases(IBDs)in patients.To further understand how TC-PTP is related to IBDs,we investigated the role of TC-PTP in maintaining the intestinal epithelial barrier using an in vivo genetic approach.Intestinal epithelial cell(IEC)-specific deletion of TC-PTP was achieved in a mouse model at steady state and in the context of dextran sulphate sodium(DSS)-induced colitis.Knockout(KO)of TC-PTP in IECs did not result in an altered intestinal barrier.However,upon DSS treatment,IECspecific TC-PTP KO mice displayed a more severe colitis phenotype with a corresponding increase in the immune response and inflammatory cytokine profile.The absence of TC-PTP caused an altered turnover of IECs,which is further explained by the role of the tyrosine phosphatase in colonic stem cell(CoSC)proliferation.Our results suggest a novel role for TC-PTP in regulating the homeostasis of CoSC proliferation.This supports the protective function of TC-PTP against IBDs,independently of its previously demonstrated role in intestinal immunity.	Stéphanie Bussières-Marmen Valérie Vinette Jeremy Gungabeesoon Isabelle Aubry Luis Alberto Pérez-Quintero Michel L Tremblay	2018	Cellular & Molecular Immunology2018，15，4：	1
3	The major genetic determinants of HIV-1control affect HLA class I peptide presentation显示文摘	International HIV Controllers Study Pereyra F Jia X McLaren P J Telenti A de Bakker P I Walker B D Ripke S Brumme C J Pulit S L Carrington M Kadie C M Carlson J M Heckerman D Graham R R Plenge R M Deeks S G Gianniny L Crawford G Sullivan J Gonzalez E Davies L Camargo A Moore JM Beattie N Gupta S Crenshaw A Burtt N P Guiducci C Gupta N Gao X Qi Y Yuki Y Piechocka-Trocha A Cutrell E Rosenberg R Moss K L Lemay P O'Leary J Schaefer T Verma P Toth I Block B Baker B Rothchild A Lian J Proudfoot J Alvino D M Vine S Addo M M Allen T M Altfeld M Henn M R Le Gall S Streeck H Haas D W Kuritzkes D R Robbins G K Shafer R W Gulick R M Shikuma C M Haubrich R Riddler S Sax P E Daar E S Ribaudo H J Agan B Agarwal S Ahern R L Allen B L Altidor S Altschuler E L Ambardar S Anastos K Anderson B Anderson V Andrady U Antoniskis D Bangsberg D Barbaro D Barrie W Bartczak J Barton S Basden P Basgoz N Bazner S Bellos N C Benson A M Berger J Bernard N F Bernard A M Birch C Bodner S J Bolan R K Boudreaux E T Bradley M Braun J F Brndjar J E Brown S J Brown K Brown S T Burack J Bush LM Cafaro V Campbell O Campbell J Carlson R H Carmichael J K Casey K K Cavacuiti C Celestin G Chambers S T Chez N Chirch L M Cimoch P J Cohen D Cohn LE Conway B Cooper D A Cornelson B Cox D T Cristofano M V Cuchural G Jr Czartoski J L Dahman J M Daly J S Davis B T Davis K Davod S M DeJesus E Dietz C A Dunham E Dunn M E Ellerin T B Eron J J Fangman J J Farel C E Ferlazzo H Fidler S Fleenor-Ford A Frankel R Freedberg K A French N K Fuchs JD Fuller J D Gaberman J Gallant J E Gandhi R T Garcia E Garmon D Gathe J C Jr Gaultier C R Gebre W Gilman F D Gilson I Goepfert P A Gottlieb M S Goulston C Groger R K Gurley T D Haber S Hardwicke R Hardy W D Harrigan P R Hawkins T N Heath S Hecht F M Henry W K Hladek M Hoffman R P Horton J M Hsu R K Huhn G D Hunt P Hupert M J Illeman M L Jaeger H Jellinger R M John M Johnson J A Johnson K L Johnson H Johnson K Joly J Jordan W C Kauffman C A Khanlou H Killian R K Kim A Y Kim D D Kinder C A Kirchner J T Kogelman L Kojic E M Korthuis P T Kurisu W Kwon D S LaMar M Lampiris H Lanzafame M Lederman M M Lee D M Lee J M Lee M J Lee E T Lemoine J Levy J A Llibre J M Liguori M A Little S J Liu A Y Lopez A J Loutfy M R Loy D Mohammed D Y Man A Mansour M K Marconi V C Markowitz M Marques R Martin J N Martin H L Jr Mayer K H McElrath M J McGhee T A McGovern B H McGowan K McIntyre D Mcleod GX Menezes P Mesa G Metroka CE Meyer-Olson D Miller A O Montgomery K Mounzer K C Nagami E H Nagin I Nahass R G Nelson M O Nielsen C Norene D L O'Connor D H Ojikutu B O Okulicz J Oladehin O O Oldfield E C Olender S A Ostrowski M Owen WF Jr Pae E Parsonnet J Pavlatos A M Perlmutter A M Pierce M N Pincus J M Pisani L Price L J Proia L Prokesch R C Pujet H C Ramgopal M Rathod A Rausch M Ravishankar J Rhame F S Richards C S Richman D D Rodes B Rodriguez M Rose R C 3rd Rosenberg E S Rosenthal D Ross P E Rubin D S Rumbaugh E Saenz L Salvaggio M R Sanchez WC Sanjana V M Santiago S Schmidt W Schuitemaker H Sestak P M Shalit P Shay W Shirvani V N Silebi V I Sizemore J M Jr Skolnik P R Sokol-Anderson M Sosman J M Stabile P Stapleton J T Starrett S Stein F Stellbrink H J Sterman FL Stone V E Stone D R Tambussi G Taplitz R A Tedaldi E M Telenti A Theisen W Torres R Tosiello L Tremblay C Tribble M A Trinh P D Tsao A Ueda P Vaccaro A Valadas E Vanig T J Vecino I Vega V M Veikley W Wade B H Walworth C Wanidworanun C Ward D J Warner D A Weber R D Webster D Weis S Wheeler D A White D J Wilkins E Winston A Wlodaver C G van't Wout A Wright D P Yang O O Yurdin D L Zabukovic B W Zachary K C Zeeman B Zhao M	2010	Science2010，330，6010：	1
4	Vitellogenin as a biomarker for environmental estrogens 显示文摘	Jones P D De Coen W M Tremblay L	2000	Water Science & Technology2000，6，：	1
5	Tumor necrosis factor reduwes brain tumor growth by enhancing macrophage recruitment and microcyst formation 显示文摘	Villeneuve J Tremblay P Vallieres L	2005	Cancer Res2005，65，9：	1
6	Heat stress attenua-tes ventilator-induced lung dysfunction in an ex vivo rat lung model显示文摘	Ribeiro S P Rhee K Tremblay L	2001	Am J Respir Crit Care Med2001，163，6：	1
7	The NMR solution structure of a mutant of the Max b/HLH/LZ free of DNA : insights into the specific and reversible DNA binding mechanism of dimeric transcription factors 显示文摘	Sauve S Tremblay L Lavigne P	2004	J Mol Biol2004，，3：	1
8	Proteomic analysis of Campylobacter jejuni 11168 biofilms reveals a role for the motility complex in biofilm formation 显示文摘	Kalmokoff M Lanthier P Tremblay T L	2006	J Bacteriol2006，188，：	1
9	Injurious ventilatory strate-gies increase cytokines and c-fos m-RNA expression in an isolated ratlung model显示文摘	Tremblay L Valenza F Ribeiro S P	1997	J Clin Invest1997，99，5：	1
10	Effects of age and age-related hearing loss on the neural representation of speech cues显示文摘	Tremblay K L Piskosz M Souza P	2003	Clin Neurophysiol2003，114，7：	1
11	HIV-1 gpl20 induces TLR2- and TLR4- mediated innate immune activation in human female genital epithelium显示文摘	Nazli A Kafka J K Ferreira V H Anipindi V Muel- ler K Osborne B J Dizzell S Chauvin S Mian M F Ouellet M Tremblay M J Mossman K L Ashkar A A Kovacs C Bowdish D M Snider D P Kaul R Kaushic C	2013	J Immunol2013，191，8：	1
12	Pro- teomic analysis of Campylobacter jejuni 11168 biofilms re- veals a role for the motility complex in biofilm formation显示文摘	KALMOKOFF M LANTHIER P TREMBLAY T L	2006	J Bacterio12006，188，12：	1
13	Computer control system for the a-275 cell 显示文摘	Girard S Simard M Tremblay J P L	1987	Light Metals1987，，：	1
14	The NM- R solution structure of a mutant of the Max b/HLH/ LZ free of DNA: insights into the specific and reversible DNA binding mechanism of dimeric transcription factors显示文摘	SAUVE S TREMBLAY L LAV1GNE P	2004	J MolBiol2004，342，：	1
15	Injurious ventilatory strategies increase cytokines and c-fos mRNA expression in an isolated rat lung model显示文摘	Tremblay L Valenza F Bibeiro S P	1997	J Clin Invest1997，99，5：	1
16	An evaluation of P- amplification factors in multistorey steel moment resisting frames 显示文摘	Tremblay R C?té B Léger P	1999	Canadian Journal of Civil Engineering1999，26，5：	1
17	The NMR solution structure of amutant of the Max B/HLH/Z free of DNA: insights into the specific and reversible DNA binding mechanism of dimeric transcription fac- tors显示文摘	SAUVE S TREMBLAY L LAVIGNE P	2004	Mol Biol2004，342，：	1
18	Variation in endophytic fungi from roots and leaves of Lepanthes(Orchidanceae)显示文摘	BAYMAN P LEBRoN L TREMBLAY R L	1997	The New Phytologist1997，135，：	1
19	Mechanisms by which E-selectin regulates diapedesis of colon cancer cells under flow conditions显示文摘	TREMBLAY P L HUOT J AUGER F A	2008	Cancer Res2008，68，13：	1
20	Thermal desorption analysis of oxygen surface complexes on carbon显示文摘	Tremblay G Vastola F J Walker J P L	1978	Carbon1978，16，：	1

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