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| 1 | Inhibitory effects of carbon dioxide insufflation on pneumoperitoneum and bowel distension after percutaneous endoscopic gastrostomy显示文摘AIM:To evaluate the inhibitory effects of carbon dioxide (CO2) insufflation on pneumoperitoneum and bowel distension after percutaneous endoscopic gastrostomy (PEG).METHODS:A total of 73 consecutive patients who were undergoing PEG were enrolled in our study.After eliminating 13 patients who fitted our exclusion criteria,60 patients were randomly assigned to either CO2 (30 patients) or air insufflation (30 patients) groups.PEG was performed by pull-through technique after threepoint fixation of the gastric wall to the abdominal wall using a gastropexy device.Arterial blood gas analysis was performed immediately before and after the procedure.Abdominal X-ray was performed at 10 min and at 24 h after PEG to assess the extent of bowel distension.Abdominal computed tomography was performed at 24 h after the procedure to detect the presence of pneumoperitoneum.The outcomes of PEG for 7 d postprocedure were also investigated.RESULTS:Among 30 patients each for the air and the CO2 groups,PEG could not be conducted in 2 patients of the CO2 group,thus they were excluded.Analyses of the remaining 58 patients showed that the patients' backgrounds were not significantly different between the two groups.The elevation values of arterial partial pressure of CO2 in the air group and the CO2 group were 2.67 mmHg and 3.32 mmHg,respectively (P = 0.408).The evaluation of bowel distension on abdominal X ray revealed a significant decrease of small bowel distension in the CO2 group compared to the air group (P < 0.001) at 10 min and 24 h after PEG,whereas there was no significant difference in large bowel distension between the two groups.Pneumoperitoneum was observed only in the air group but not in the CO2 group (P = 0.003).There were no obvious differences in the laboratory data and clinical outcomes after PEG between the two groups.CONCLUSION:There was no adverse event associated with CO2 insufflation.CO2 insufflation is considered to be safer and more comfortable for PEG patients because of the lower incidence of pneumoperitoneum and less distension of the small bowel. | Shinji Nishiwaki Hiroshi Araki Motoshi Hayashi Jun Takada Masahide Iwashita Atsushi Tagami Hiroo Hatakeyama Takao Hayashi Teruo Maeda Koshiro Saito | 2012 | World Journal of Gastroenterology2012，18，27： | 7 |
| 2 | Safety and efficacy of carbon dioxide insufflation during gastric endoscopic submucosal dissection显示文摘AIM: To compare the safety and efficacy of carbon dioxide(CO2) and air insufflation during gastric endoscopic submucosal dissection(ESD).METHODS: This study involved 116 patients who underwent gastric ESD between January and December 2009.After eliminating 29 patients who fit the exclusion criteria,87 patients,without known pulmonary dysfunction,were randomized into the CO2 insufflation(n = 36) or air insufflation(n = 51) groups.Standard ESD was performed with a CO2 regulation unit(constant rate of 1.4 L/min) used for patients undergoing CO2 insufflation.Patients received diazepam for conscious sedation and pentazocine for analgesia.Transcutaneous CO2 tension(Ptc CO2) was recorded 15 min before,during,and after ESD with insufflation.Ptc CO2,the correlation between Ptc CO2 and procedure time,and ESD-related complications were compared between the two groups.Arterial blood gases were analyzed after ESD in the first 30 patients(12 with CO2 and 18 with air insufflation) to assess the correlation between arterial blood CO2 partial pressure(Pa CO2) and Ptc CO2.RESULTS: There were no differences in respiratoryfunctions,median sedative doses,or median procedure times between the groups.Similarly,there was no significant difference in post-ESD blood gas parameters,including Pa CO2,between the CO2 and air groups(44.6 mm Hg vs 45 mm Hg).Both groups demonstrated median p H values of 7.36,and none of the patients exhibited acidemia.No significant differences were observed between the CO2 and air groups with respect to baseline Ptc CO2(39 mm Hg vs 40 mm Hg),peak Ptc CO2 during ESD(52 mm Hg vs 51 mm Hg),or median Ptc CO2 after ESD(50 mm Hg vs 50 mm Hg).There was a strong correlation between Pa CO2 and Ptc CO2(r = 0.66; P < 0.001).The incidence of Mallory-Weiss tears was significantly lower with CO2 insufflation than with air insufflation(0% vs 15.6%,P = 0.013).CO2 insufflation did not cause any adverse events,such as CO2 narcosis or gas embolisms.CONCLUSION: CO2 insufflation during gastric ESD results in similar blood gas levels as air insufflation,and also reduces the incidence of Mallory-Weiss tears. | Jun Takada Hiroshi Araki Fumito Onogi Takayuki Nakanishi Masaya Kubota Takashi Ibuka Masahito Shimizu Hisataka Moriwaki | 2015 | World Journal of Gastroenterology2015，21，26： | 6 |
| 3 | B‐cell surface marker analysis for improvement of rituximab prophylaxis in ABO‐incompatible adult living donor liver transplantation显示文摘 | Hiroto Egawa Katsuyuki Ohmori Hironori Haga Hiroaki Tsuji Kimiko Yurugi Aya Miyagawa‐Hayashino Fumitaka Oike Akinari Fukuda Jun Yoshizawa Yasutsugu Takada Koichi Tanaka Taira Maekawa Kazue Ozawa Shinji Uemoto | 2007 | Liver Transpl2007，，4： | 1 |
| 4 | Magnetic properties of La–Co substituted M-type strontium hexaferrites prepared by polymerizable complex method显示文摘 | Takeyuki Kikuchi Tatsuya Nakamura Tohru Yamasaki Makoto Nakanishi Tatsuo Fujii Jun Takada Yasunori Ikeda | 2010 | Journal of Magnetism and Magnetic Materials2010，，16： | 1 |
| 5 | Estimation of cloverbiomass and percentage in a performance trial of whiteclover-timothy binary mixtures : use of multiple regressionequations incorporating plant cover measured with thegrid-point plate显示文摘 | Chen Jun Okumura K Takada H | 2010 | Grassland Science2010，，： | 1 |
| 6 | Effects of sunlight exposure on the human tooth enamel ESR spectra used for dose reconstruction显示文摘 | Jiao Ling Takada Jun Endo Satoru | 2007 | Journal of Radiation Research2007，48，1： | 1 |
| 7 | Characterization of Amorphous Tungsten Trioxide Thin Films Prepared by RF Magnetron Sputtering Method 显示文摘 | Tokuro Nanba Tadashi Takahashi Jun Takada | 1994 | Joural of Non - Crystalline Sloids1994，178，： | 1 |
| 8 | Characterization of amorphous tungsten trioxide thin films prepared by RF magnetron sputtering method 显示文摘 | Tokuro Nanba Tadashi Takahashi Jun Takada | 1994 | Journal of Non - Crystalline Sloids1994，178，： | 1 |
| 9 | Effects of sunlight exposure on the human tooth enamel ESR spectra used for dose reconstruction显示文摘 | Jiao Ling Takada Jun Endo Satoru | 2007 | Journal of Radiation Research2007，48，1： | 1 |
| 10 | Effect of risedronate on speed of sound in postmenopausal women with osteoporosis显示文摘AIM: To examine the effects of treatment with risedronate for 1 year on speed of sound(SOS) of the calcaneus and bone turnover markers in postmenopausal women with osteoporosis. METHODS: Thirty-eight postmenopausal women with osteoporosis who had been treated with risedronate for > 1 year were enrolled in the study. The SOS and bone turnover markers were monitored during treatment with risedronate for 1 year. RESULTS: The urinary levels of cross-linked N-terminal telopeptides of type Ⅰ collagen and serum levels of alkaline phosphatase were significantly decreased at 3 mo(-34.7%) and 12 mo(-21.2%), respectively, compared with the baseline values. The SOS increased modestly, but significantly by 0.65% at 12 mo compared with the baseline value. Treatment with risedronate elicited an increase in the SOS of the calcaneus exceeding the coefficient of variation in vivo(0.27%). CONCLUSION: The present study confirmed that risedronate suppressed bone turnover and elicited a clinically significant increase in the SOS of the calcaneus in postmenopausal women with osteoporosis. | Jun Iwamoto Tetsuya Takada Yoshihiro Sato Hideo Matsumoto | 2013 | World Journal of Orthopedics2013，4，4： | 0 |
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