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| 1 | EIN2, a Bifunctional Transducer of Ethylene and Stress Responses in Arabidopsis显示文摘 | Alonso JM Hirayama Takashi Roman Gregg | 1999 | Science1999，，283： | 1 |
| 2 | Perception and transduction of abscisic acid signals: keys to the function of the versatile plant hormone ABA显示文摘 | Takashi Hirayama Kazuo Shinozaki | 2007 | Trends in Plant Science2007，，8： | 1 |
| 3 | Trypanocidal activity of extracts and compounds from the stem bark of Anogeissus leiocarpus and Terminalia avicennoides显示文摘 | Mohammed N. Shuaibu Ponchang T. A. Wuyep Tetsuo Yanagi Kenji Hirayama Akitoyo Ichinose Takashi Tanaka Isao Kouno | 2008 | Parasitology Research2008，，： | 1 |
| 4 | Responsive-toAntagonist1,A Menkes/Wilson Disease Related Copper Transporter,Is Required for Ethylene Signaling in Arabidopsis显示文摘 | Takashi Hirayama Joseph J | 1999 | Cell1999，97，： | 1 |
| 5 | Pleural effusion VEGF levels as a prognostic factor of malignant pleural mesothelioma显示文摘 | Noriko Hirayama Chiharu Tabata Rie Tabata Risa Maeda Akihiro Yasumitsu Shusai Yamada Kozo Kuribayashi Kazuya Fukuoka Takashi Nakano | 2010 | Respiratory Medicine2010，，1： | 1 |
| 6 | Molecular responses to water stress inArabidopsis thaliana显示文摘 | Kazuo Shinozaki Kazuko Yamaguchi-Shinozaki Tsuyoshi Mizoguchi Takeshi Urao Takeshi Katagiri Kazuo Nakashima Hiroshi Abe Kazuya Ichimura Quian Liu Tokihiko Nanjyo Yuichi Uno Satoshi Luchi Motoaki Seki Takuya Ito Takashi Hirayama Koji Mikami | 1998 | Journal of Plant Research1998，，2： | 1 |
| 7 | Role of cardiac sympathetic nerves in preventing orthostatic hypotension in Parkinson’s disease显示文摘 | Tomohiko Nakamura Masaaki Hirayama Takashi Hara Yasuaki Mizutani Junichiro Suzuki Hirohisa Watanabe Gen Sobue | 2014 | Parkinsonism and Related Disorders2014，，： | 1 |
| 8 | Prepara- tion of ZrB2 - SiC composites by arc melting and their properties 显示文摘 | Tu Rong Hirayama Hidenori Goto Takashi | 2008 | Journal of the Ceramic Society of Japan2008，116，： | 1 |
| 9 | Lymphoepithelial Cyst of the Pancreas: Report of a Case显示文摘 | Akihito Idetsu Hitoshi Ojima Kana Saito Isao Hirayama Yasuo Hosouchi Yasuji Nishida Takashi Nakajima Hiroyuki Kuwano | 2008 | Surgery Today2008，，1： | 1 |
| 10 | Preparation of ZrB2- SiC composites by arc melting and their properties 显示文摘 | Tu Rong Hirayama Hidenori Goto Takashi | 2008 | J Ceram Soc Ja- pan2008，116，3： | 1 |
| 11 | Trypanocidal activity of extracts and compounds from the stem bark of Anogeissus leiocarpus and Terminalia avicennoides显示文摘 | Mohammed N. Shuaibu Ponchang T. A. Wuyep Tetsuo Yanagi Kenji Hirayama Akitoyo Ichinose Takashi Tanaka Isao Kouno | 2008 | Parasitology Research2008，，4： | 1 |
| 12 | In Vivo Development of Fetal Pig Kidneys in Mature Monkeys under Clinically Approved Immunosuppressant Drugs显示文摘Controlling the immune response with only clinically approved immunosuppressant drugs is difficult in renal heterotra ns plantation from pigs to nonhuman primates.Moreover,to the best of our knowledge,no reports exist on the use of fetal pigs as kidney donors.This study aimed to compare the degree of transplant rejection between neonatal and fetal kidneys,with genetically unmodified pigs as donors and cynomolgus monkeys as recipients.The left kidneys of the recipient monkeys were removed,followed by transplantation of neonatal as well as fetal pig kidneys,which had undergone vascular anastomosis at the same site,into the retroperitoneum.Immunosuppression was performed with only US Food and Drug Administration-approved drugs.The fetal kidneys were transplanted into the omentum and paraaortic regions of cynomolgus monkeys.Consequently,the engraftment and development of the transplanted tissues were pathologically examined by sampling over time(twice in each experiment).An acute rejection was observed after a few weeks in neonatal renal grafts with vascular anastomosis.However,fetal pig kidneys were spared from rejection despite the administration of the same immunosuppressive protocol to the monkeys and the recipient blood vessels flowing into the fetal kidneys.The immunogenicity of fetal kidneys in pig-monkey renal heterotransplantation was lower than that of neonatal kidneys. | Tsuyoshi Takamura Kenji Matsui Naoto Matsumoto Yatsumu Saito Toshinari Fujimoto Susumu Tajiri Shuichiro Yamanaka Kei Matsumoto Akimitsu Kobayashi Izumi Yamamoto Hiroshi Sasaki Haruyuki Hirayama Hitomi Matsunari Kazuaki Nakano Hiroshi Nagashima Akihiko Kiyoshi Takao Kuroda Makoto Inoue Takeshi Miyawaki Takashi Yokoo Eiji Kobayashi | 2022 | Engineering2022，8，3： | 0 |
| 13 | Exome-wide variation in a diverse barley panel reveals genetic associations with ten agronomic traits in Eastern landraces显示文摘Barley(Hordeum vulgare ssp.vulgare)is one of the first crops to be domesticated and is adapted to a wide range of environments.Worldwide barley germplasm collections possess valuable allelic variations that could further improve barley productivity.Although barley genomics has offered a global picture of allelic variation among varieties and its association with various agronomic traits,polymorphisms from East Asian varieties remain scarce.In this study,we analyze exome polymorphisms in a panel of 274 barley varieties collected worldwide,including 137 varieties from East Asian countries and Ethiopia.We reveal the underlying population structure and conduct genome-wide association studies for 10 agronomic traits.Moreover,we examin genome-wide associations for traits related to grain size such as awn length and glume length.Our results demonstrate the value of diverse barley germplasm panels containing Eastern varieties,highlighting their distinct genomic signatures relative to Western subpopulations. | June-Sik Kim Kotaro Takahagi Komaki Inoue Minami Shimizu Yukiko Uehara-Yamaguchi Asaka Kanatani Daisuke Saisho Ryuei Nishii Alexander ELipka Takashi Hirayama Kazuhiro Sato Keiichi Mochida | 2023 | Journal of Genetics and Genomics2023，50，4： | 0 |
| 14 | Recent trends in the prevalence and distribution of colonic diverticula in Japan evaluated using computed tomography colonography显示文摘BACKGROUND Computed tomography colonography(CTC)may be superior to colonoscopy and barium enema for detecting diverticula.However,few studies have used CTC to diagnose diverticula.AIM To evaluate the current prevalence and distribution of colonic diverticula in Japan using CTC.METHODS This study was conducted as part of the Japanese National Computed Tomographic Colonography Trial,which included 1181 participants from 14 hospitals in Japan.We analyzed the prevalence and distribution of colonic diverticula and their relationships with age and sex.The relationship between the diverticula and the length of the large intestine was also analyzed.RESULTS Diverticulosis was present in 48.1%of the participants.The prevalence of diverticulosis was higher in the older participants(P<0.001 for trend).The diverticula seen in younger participants were predominantly located in the right-sided colon.Older participants had a higher frequency of bilateral type(located in the rightand left-sided colon)diverticulosis(P<0.001 for trend).The length of the large intestine with multiple diverticula in the sigmoid colon was significantly shorter in those without diverticula(P<0.001).CONCLUSION The prevalence of colonic diverticulosis in Japan is higher than that previously reported.The prevalence was higher,and the distribution tended to be bilateral in older participants. | Noriyuki Isohata Koichi Nagata Kenichi Utano Ryoichi Nozaki Satoshi Nozu Takashi Kato Shigeyoshi Kijima Hiroshi Matsumoto Kenichiro Majima Yasuji Ryu Michiaki Hirayama Shungo Endo | 2021 | World Journal of Gastroenterology2021，27，27： | 0 |
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