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| 1 | Management of gastric mucosa-associated lymphoid tissue lymphoma in patients with extra copies of the MALT1 gene显示文摘AIM To identify the clinical features of gastric mucosaassociated lymphoid tissue(MALT) lymphoma with extra copies of MALT1.METHODS This is a multi-centered,retrospective study. We reviewed 146 patients with MALT lymphoma in the stomach who underwent fluorescence in situ hybridization analysis for t(11;18) translocation. Patients were subdivided into patients without t(11;18) translocation or extra copies of MALT1(Group A,n = 88),patients with t(11;18) translocation(Group B,n = 27),and patients with extra copies of MALT1(Group C,n = 31). The clinical background,treatment,and outcomes of each group were investigated.RESULTS Groups A and C showed slight female predominance,whereas Group B showed slight male predominance. Mean ages and clinical stages at lymphoma diagnosis were not different between groups. Complete response was obtained in 61 patients in Group A(69.3%),22 in Group B(81.5%),and 21 in Group C(67.7%). Helicobacter pylori(H. pylori) eradication alone resulted in complete remission in 44 patients in Group A and 13 in Group C. In Group B,14 patients underwent radiotherapy alone,which resulted in lymphoma disappearance. Although the difference was not statistically significant,event-free survival in Group C tended to be inferior to that in Group A(P = 0.10).CONCLUSION Patients with t(11;18) translocation should be treated differently from others. Patients with extra copies of MALT1 could be initially treated with H. pylori eradication,similar to patients without t(11;18) translocation or extra copies of MALT1. | Masaya Iwamuro Ryuta Takenaka Masahiro Nakagawa Yuki Moritou Shunsuke Saito Shinichiro Hori Tomoki Inaba Yoshinari Kawai Tatsuya Toyokawa Takehiro Tanaka Tadashi Yoshino Hiroyuki Okada | 2017 | World Journal of Gastroenterology2017，23，33： | 3 |
| 2 | Retreatment with nedaplatin in patients with recurrent gynecological cancer after the development of hypersensitivity reaction to carboplatin显示文摘 | Takahide Arimoto Katsutoshi Oda Shunsuke Nakagawa Kei Kawana Takehiro Tsukazaki Katsuyuki Adachi Yoko Matsumoto Tetsu Yano Shiro Kozuma Yuji Taketani | 2012 | Journal of Obstetrics and Gynaecology Research2012，，1： | 1 |
| 3 | Surgical treatment for metastatic malignancies. Pulmonary metastasis: indications and outcomes显示文摘 | Haruhiko Kondo Takehiro Okumura Yasuhisa Ohde Kazuo Nakagawa | 2005 | International Journal of Clinical Oncology2005，，2： | 1 |
| 4 | Multi-objective genetic algorithm-based sample selection for partial least squares model building with applications to near-infrared spectroscopic data 显示文摘 | Hideyuki Shinzawa Boyan Li Takehiro Nakagawa | 2006 | Applied Spectroscopy2006，60，6： | 1 |
| 5 | Retreatment with nedaplatin in patients with recurrent gynecological cancer after the development of hypersensitivity reaction to carboplatin显示文摘 | Takahide Arimoto Katsutoshi Oda Shunsuke Nakagawa Kei Kawana Takehiro Tsukazaki Katsuyuki Adachi Yoko Matsumoto Tetsu Yano Shiro Kozuma Yuji Taketani | 2012 | Journal of Obstetrics and Gynaecology Research2012，，1： | 1 |
| 6 | Multi-objective genetic algorithm-based sample selection for partial least squares model building with applications to near-infrared spectroscopic data显示文摘 | Hideyuki Shinzawa Boyan Li Takehiro Nakagawa | 2006 | Applied Spectroscopy2006，60，6： | 1 |
| 7 | Efficacy and safety of endoscopic submucosal dissection for gastric tube cancer:A multicenter retrospective study显示文摘BACKGROUND Recent improvements in the prognosis of patients with esophageal cancer have led to the increased occurrence of gastric tube cancer(GTC)in the reconstructed gastric tube.However,there are few reports on the treatment results of endoscopic submucosal dissection(ESD)for GTC.AIM To evaluate the efficacy and safety of ESD for GTC after esophagectomy in a multicenter trial.METHODS We retrospectively investigated 48 GTC lesions in 38 consecutive patients with GTC in the reconstructed gastric tube after esophagectomy who had undergone ESD between January 2005 and December 2019 at 8 institutions participating in the Okayama Gut Study group.The clinical indications of ESD for early gastric cancer were similarly applied for GTC after esophagectomy.ESD specimens were evaluated in 2-mm slices according to the Japanese Classification of Gastric Carcinoma with curability assessments divided into curative and non-curative resection based on the Gastric Cancer Treatment Guidelines.Patient characteristics,treatment results,clinical course,and treatment outcomes were analyzed.RESULTS The median age of patients was 71.5 years(range,57-84years),and there were 34 men and 4 women.The median observation period after ESD was 884 d(range,8-4040 d).The median procedure time was 81 min(range,29-334 min),the en bloc resection rate was 91.7%(44/48),and the curative resection rate was 79%(38/48).Complications during ESD were seen in 4%(2/48)of case,and those after ESD were seen in 10%(5/48)of case.The survival rate at 5 years was 59.5%.During the observation period after ESD,10 patients died of other diseases.Although there were differences in the procedure time between institutions,a multivariate analysis showed that tumor size was the only factor associated with prolonged procedure time.CONCLUSION ESD for GTC after esophagectomy was shown to be safe and effective. | Takuya Satomi Seiji Kawano Tomoki Inaba Masahiro Nakagawa Hirokazu Mouri Masao Yoshioka Shoichi Tanaka Tatsuya Toyokawa Sayo Kobayashi Takehiro Tanaka Hiromitsu Kanzaki Masaya Iwamuro Yoshiro Kawahara Hiroyuki OkadaDepartment of Gastroenterology and Hepatology | 2021 | World Journal of Gastroenterology2021，27，11： | 0 |
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