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| 1 | Continuous wound infusion of local anaesthetic agents following colorectal surgery:Systematic review and meta-analysis显示文摘AIM:To provide a specifi c review and meta-analysis of the available evidence for continuous wound infusion of local anaesthetic agents following midline laparoto-my for major colorectal surgery. METHODS: Medline, Embase, trial registries, conference proceedings and article reference lists were searched to identify randomised, controlled trials of continuous wound infusion of local anaesthetic agents following colorectal surgery. The primary outcomes were opioid consumption, pain visual analogue scores (VASs), return to bowel function and length of hospital stay. Weighted mean difference were calculated for continuous outcomes. RESULTS: Five trials containing 542 laparotomy wounds were eligible for inclusion. There was a sig- nificant decrease in post-operative pain VAS at rest on day 3 (weighted mean difference: -0.43; 95% CI: -0.81 to -0.04; P = 0.03) but not on post-operative day 1 and 2. Local anaesthetic infusion was associated with a signifi cant reduction in pain VAS on movement on all three post-operative days (day 1 weighted mean difference: -1.14; 95% CI: -2.24 to -0.041; P = 0.04, day 2 weighted mean difference: -0.97, 95% CI: -1.91to -0.029; P = 0.04, day 3 weighted mean difference: -0.61; 95% CI: 1.01 to -0.20; P = 0.0038). Local an- aesthetic wound infusion was associated with a signifi - cant decrease in total opioid consumption (weighted mean difference: -40.13; 95% CI: -76.74 to -3.53; P = 0.03). There was no signifi cant decrease in length of stay (weighted mean difference: -20.87; 95% CI: -46.96 to 5.21; P = 0.12) or return of bowel function (weighted mean difference: -9.40; 95% CI: -33.98 to 15.17; P = 0.45). CONCLUSION: The results of this systematic re- view and meta-analysis suggest that local anaesthetic wound infusion following laparotomy for major color- ectal surgery is a promising technique but do not pro- vide conclusive evidence of benefi t. Further research is required including cost-effectiveness analysis. | Alan Karthikesalingam Stewart R Walsh Sheraz R Markar Umar Sadat Tjun Y Tang Charles M Malata | 2008 | World Journal of Gastroenterology2008，14，34： | 4 |
| 2 | 生理过度觉醒相关失眠增加高血压风险显示文摘先前的研究显示,失眠和客观睡眠时间过短与高血压风险增加相关,并推测其潜在的机制是生理过度觉醒。在该研究中,研究者通过多次睡眠潜伏期试验(multiplesleeplatencytest,MSLT)——一种睡眠/觉醒的标准测试,探讨与生理过度觉醒相关的失眠是否与高血压风险增加相关。 | Li Y Vgontzas AN Fernandez-Mendoza J Bixler EO Sun Y Zhou J Ren R Li T Tang X 戴伦 练桂丽 | 2015 | 中华高血压杂志2015，23，2： | 2 |
| 3 | Discovery and analysis of hepatocellular carcinoma genes using cDNA microarrays显示文摘 | Li Y Li Y Tang R | 2001 | J Cancer Res Clin Oncol2001，128，7： | 1 |
| 4 | Insights into oil cracking based on laboratory experiments显示文摘 | Hill R J Tang Y C Kaplan I R | 2003 | Org Geochem2003，34，12： | 1 |
| 5 | The uptake of copper by plants dominantly growing on copper mining spoils along the Yangtze River, the People's Republic of China 显示文摘 | Tang S R Wilke B M Huang C Y | 1999 | Plant Soil1999，209，： | 1 |
| 6 | Study on the preparation of orange peel cellulose adsorbents and biosorption of Cd2+ from aqueous solution显示文摘 | Li X M Tang Y R Xuan Z X | 2007 | Separation and Purification Technology2007，55，1： | 1 |
| 7 | Effects of nutritionallevel on pork quality and gene expression of (X -calpain andcalpastatin in muscle of finishing pigs显示文摘 | Tang R Y Yu B Zhang K Y | 2010 | Meat Science2010，85，4： | 1 |
| 8 | Effect of dietary supplementation of chitosan and galacto-mannan-oligo- saecharides on serum parameters and the insulin-like growth factor-I mRNA expression in early weaned pig- lets显示文摘 | Tang Z R Yin Y L Nyachoti C M | 2005 | Domest Anim Endocrin2005，28，： | 1 |
| 9 | Hepatic Niemann-Pick Cl-like 1 regulates biliary cholesterol concentration and is a target of ezetimi- be显示文摘 | Temel R E Tang W Ma Y | 2007 | J Clin Invest2007，117，7： | 1 |
| 10 | 2013, Antigenic and genetic characterization of a European avian-like H1N1 swine influenza virus from a boy in China in 2011显示文摘 | Qi x Cui L Jiao Y Pan Y Li X Zu R Huo X Wu B Tang F Song Y Zhou M Wang H Cardona C J Xing Z | 2013 | Archives of Virology2013，158，1： | 1 |
| 11 | Synthesis and characterization of ternary CuInS2nanorods via a hydrothermal route显示文摘 | Xiao J P Xie Y Tang R | 2001 | Journal of Solid State Chemistry2001，161，2： | 1 |
| 12 | Adaptation of HIV-1to human leukocyte antigen class I显示文摘 | Kawashima Y Pfafferott K Frater J Matthews P Payne R Addo M Gatanaga H Fujiwara M Hachiya A Koizumi H Kuse N Oka S Duda A Prendergast A Crawford H Leslie A Brumme Z Brumme C Allen T Brander C Kaslow R Tang J Hunter E Allen S Mulenga J Branch S Roach T John M Mallal S Ogwu A Shapiro R Prado J G Fidler S Weber J Pybus O G Klenerman P Ndung'u T Phillips R Heckerman D Harrigan P R Walker B D Takiguchi M Goulder P | 2009 | Nature2009，458，7238： | 1 |
| 13 | Targeted delivery of vascular endothelial growth factor improves stem cell therapy in a rat myocardial infarction model显示文摘 | Tang Y Gan X Cheheltani R | 2014 | Nanomedicine2014，10，8： | 1 |
| 14 | Cloning and expression pattern of the human NDRG3 gene 显示文摘 | Zhao W Tang R Huang Y | 2001 | Biochim Biophys Acta2001，1519，12： | 1 |
| 15 | Contrasting effects of elevated CO2 on Cu and Cd uptake by different rice varieties grown on contaminated soils with two levels of metals: Implication for phytoextraction and food safety显示文摘 | Li Z Y Tang S R Deng X F | 2010 | Journal of hazardous materials2010，177，13： | 1 |
| 16 | Hydrogen peroxide stimulates macrophages and monocytes to actively release HMGB1 显示文摘 | Tang D Shi Y Kang R | 2007 | J Leukoc Biol2007，81，3： | 1 |
| 17 | Differential effects of enrichment on learning and memory function in NR2B transgenic mice显示文摘 | Wang H Feng R | 2001 | Neuropharmacology2001，41，6： | 1 |
| 18 | A novel density-tunable nanoeomposites of CdTe quantum dots linked to dendrimer-tethered multiwall carbon nanotubes显示文摘 | Zeng Y L Tang C R Wang H W Jiang J H Tian M N Shen G L Yu R Q | 2008 | Spectrochimica Acta Part A:Molecular and Biomolecular Spectroscopy2008，70，5： | 1 |
| 19 | Persistent recognition of autolo- gous virus by high-avidity CD8 T cells in chronic, progressive human immunodefieiency virus type 1 infection 显示文摘 | Draenert R Verrine L Tang Y | 2004 | J Virol2004，78，2： | 1 |
| 20 | A new approach to quality function deployment planning with financial consideration 显示文摘 | TANG J F FUNG R Y K XU B | 2002 | Computer and Operation Research2002，29，11： | 1 |
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