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| 1 | Cotton GhBAK1 Mediates Verticillium Wilt Resistance and Cell Death显示文摘导致病毒的基因 silencing (VIGS ) 由将他们的表示击倒为单个基因的功能的分析提供一条强大的途径。我们采用了这条途径把在对 Verticillium 抵抗的棉花的基因功能枯萎,世界范围的大多数破坏疾病之一。我们这里证明高度有效的 VIGS 在与部分抵抗引起线(CA4002 ) 到 Verticillium 的一朵棉花被获得枯萎,并且 GhMKK2 和 GhVe1 为它的抵抗被要求到 Verticillium 枯萎。Arabidopsis AtBAK1/SERK3,在工厂疾病抵抗的一个中央管理者,与五个成员,一起属于体的 embryogenesis 受体 kinases (SERK ) 的一个亚科 AtSERK1 到 AtSERK5。二 BAK1 orthologs 和一 SERK1 ortholog 在棉花染色体被识别。重要地, GhBAK1 为 CA4002 抵抗被要求到 Verticillium 枯萎。令人惊讶地, GhBAK1 的 silencing 是足够的触发在棉花伴有反应的氧种类的生产的房间死亡。这结果从 AtBAK1 和 AtSERK4 在房间死亡控制在玩冗余的函数的 Arabidopsis 是不同的。显然,而 AtSERK4/5 是在 Arabidopsis 的最新发展的基因,棉花仅仅发展了 SERK1 和 BAK1。我们的研究在 Verticillium 显示 BAK1 的功能的重要性枯萎抵抗并且在不同植物种类建议 SERK 家庭成员的动态进化。 | Xiquan Gao Fangjun Li Maoying Li Ali S.Kianinejad Jane K.Dever Terry A.Wheeler Zhaohu Li Ping He Libo Shan | 2013 | Journal of Integrative Plant Biology2013，55，7： | 13 |
| 2 | Interactions between CagA and smoking in gastric cancer显示文摘AIM: To examine the interactions between cytotoxinassociated gene (CagA) positive Helicobacter pylori infection and smoking in non-cardiac gastric cancer.METHODS: A case-control study (257 cases and 514 frequency-matched controls) was conducted from September 2008 to July 2010 in Xi’an,China.Cases were newly diagnosed,histologically confirmed non-cardiac cancer.Controls were randomly selected from similar communities to the cases and were further matched by sex and age (± 5 years).A face-to-face interview was performed by the investigators for each participant.Data were obtained using a standardized questionnaire that included questions regarding known or suspected lifestyle and environmental risk factors of gastric cancer.A 5 mL sample of fasting venous blood was taken.CagA infection was serologically detected by enzymelinked immunosorbent assays.RESULTS: Smoking and CagA infection were statistically significant risk factors of non-cardiac cancer.CagA was categorized in tertiles,and the odds ratio (OR) was 12.4 (95% CI: 6.1-20.3,P = 0.003) for CagA after being adjusted for confounding factors when the highexposure category was compared with the low-exposure category.Smokers had an OR of 5.4 compared with subjects who never smoked (95% CI: 2.3-9.0,P = 0.002).The OR of non-cardiac cancer was 3.5 (95% CI: 1.8-5.3) for non-smokers with CagA infection,3.5 (95% CI: 1.9-5.1) for smokers without CagA infection,and 8.7 (95% CI: 5.1-11.9) for smokers with CagA infection compared with subjects without these risk factors.After adjusting for confounding factors,the corresponding ORs of non-cardiac cancer were 3.2 (95% CI: 1.5-6.8),2.7 (95% CI: 1.3-4.9) and 19.5 (95% CI: 10.3-42.2),respectively.There was a multiplicative interaction between smoking and CagA,with a synergistic factor of 2.257 (Z = 2.315,P = 0.021).CONCLUSION: These findings support a meaningful interaction between CagA and smoking for the risk of gastric cancer which may have implications for its early detection. | xiao-Qin wang Hong Yan Paul D Terry Jian-Sheng Wang Li Cheng Wen-An Wu Sen-Ke Hu | 2011 | World Journal of Gastroenterology2011，17，28： | 6 |
| 3 | Theoretical investigations of electrical transport properties in CoSb3 skutterudites under hydrostatic loadings显示文摘CoSb_3-based skutterudites have been a benchmark mid-temperature thermoelectric material under intensive experimental and theoretical studies for decades.Doping and filling, to the first order, alter the crystal lattice constant of CoSb3 in the context of 'chemical pressure.' In this work, we employed ab initio density functional theory in conjunction with semiclassical Boltzmann transport theory to investigate the mechanical properties and especially how hydrostatic loadings, i.e., 'physical pressure,' impact the electronic band structure, Seebeck coefficient,and power factor of pristine CoSb_3. It is found that hydrostatic pressure enlarges the band gap, suppresses the density of states(DOS) near the valence band edge, and fosters the band convergence between the valley bands and the conduction band minimum(CBM). By contrast,hydrostatic tensile reduces the band gap, increases the DOS near the valence band edge, and diminishes the valley bands near the CBM. Therefore, applying hydrostatic pressure provides an alternative avenue for achieving band convergence to improve thermoelectric properties of N-type CoSb3, which is further supported by our carrier concentration studies. These results provide valuable insight into the further improvement of thermoelectric performance of CoSb3-based skutterudites via a synergy of physical and chemical pressures. | Chongze Hu Peter Ni Li Zhan Huijuan Zhao Jian He Terry M. Tritt Jingsong Huang Bobby G. Sumpter | 2018 | Rare Metals2018，37，4： | 5 |
| 4 | Association of XPG rs2094258 polymorphism with gastric cancer prognosis显示文摘BACKGROUND The xeroderma pigmentosum group G(XPG)gene at chromosome 13q33 consists of 15 exons,which may be related to the occurrence and development of gastric cancer(GC).AIM To examine the association of several common single nucleotide polymorphisms(SNPs)of the XPG gene with GC risk and survival.METHODS Five SNPs of XPG(rs2094258,rs751402,rs873601,rs2296147,and rs1047768)were genotyped by PCR restriction fragment length polymorphism in 956 histologically confirmed GC cases and 1012 controls in North China.GC patients were followed for survival status and,if deceased,cause of death.Logistic regression and Cox regression were used for analysing associations of XPG SNPs with risk of GC and prognosis,respectively.For rs2094258,heterozygous model(CT vs CC),homozygous model(TT vs CC),recessive model(TT vs CT+CC),and dominant model(TT+CT vs CC)were analyzed.RESULTS None of the examined loci were statistically associated with GC risk,although rs2296147 was marginally associated with GC risk(P=0.050).GC patients with the rs2094258 CT+CC genotype showed worse survival than those with the TT genotype(log-rank test,P=0.028),and patients with the CC genotype had a tendency of unfavourable prognosis compared with those with the TT+CT genotype(log-rank test,P=0.039).The increase in C alleles of rs2094258[hazard ratio(HR)=1.19,95%confidence interval(CI):1.02-1.45,P=0.037]were associated with the long-term survival of GC cases.Other risk factors for survival included tumor differentiation(HR=4.51,95%CI:1.99-8.23,P<0.001),lymphovascular invasion(HR=1.97,95%CI:1.44-3.01,P<0.001),and use of chemotherapy(HR=0.81,95%CI:0.63-0.98,P=0.041).CONCLUSION The XPG rs2094258 polymorphism may be associated with overall survival in GC patients. | Xiao-Qin Wang Paul D Terry Yang Li Yue Zhang Wen-Jing Kou Ming-Xu Wang | 2019 | World Journal of Gastroenterology2019，25，34： | 4 |
| 5 | 基于元胞自动机降尺度方法的1km分辨率全球土地利用数据集(2010~2100)(英文)显示文摘 | 李雪草 俞乐 徐伊迪 杨军 宫鹏 Terry Sohl Nicholas Clinton Wenyu Li Zhiliang Zhu Xiaoping Liu | 2016 | Science Bulletin2016，61，21： | 3 |
| 6 | Dysfunctional stem and progenitor cells impair fracture healing with age显示文摘Successful fracture healing requires the simultaneous regeneration of both the bone and vasculature;mesenchymal stem cells (MSCs) are directed to replace the bone tissue, while endothelial progenitor cells (EPCs) form the new vasculature that supplies blood to the fracture site. In the elderly, the healing process is slowed, partly due to decreased regenerative function of these stem and progenitor cells. MSCs from older individuals are impaired with regard to cell number, proliferative capacity, ability to migrate, and osteochondrogenic differentiation potential. The proliferation, migration and function of EPCs are also compromised with advanced age. Although the reasons for cellular dysfunction with age are complex and multidimensional, reduced expression of growth factors, accumulation of oxidative damage from reactive oxygen species, and altered signaling of the Sirtuin-1 pathway are contributing factors to aging at the cellular level of both MSCs and EPCs. Because of these geriatric-specific issues, effective treatment for fracture repair may require new therapeutic techniques to restore cellular function. Some suggested directions for potential treatments include cellular therapies, pharmacological agents, treatments targeting age-related molecular mechanisms, and physical therapeutics. Advanced age is the primary risk factor for a fracture, due to the low bone mass and inferior bone quality associated with aging;a better understanding of the dysfunctional behavior of the aging cell will provide a foundation for new treatments to decrease healing time and reduce the development of complications during the extended recovery from fracture healing in the elderly. | Diane R Wagner Sonali Karnik Zachary J Gunderson Jeffery J Nielsen Alanna Fennimore Hunter J Promer Jonathan W Lowery M Terry Loghmani Philip S Low Todd O McKinley Melissa A Kacena Matthias Clauss Jiliang Li | 2019 | World Journal of Stem Cells2019，11，6： | 3 |
| 7 | 影响地下矿山充填质量的因素显示文摘澳大利亚地下采矿工业一直在持续推行充填法采矿技术.近些年来,西澳大利亚矿业学校为西澳大利亚的一些矿业公司完成了一些研究课题,借以确定经济上最合理和土工技术上最合适的充填方法.近年来的研究表明,充填材料的矿物组分和氧化程度以及水泥种类对充填体强度和充填质量都有很大影响.文章将评述在西澳大利亚两座大型地下矿山研究膏体胶结充填和水砂胶结充填工作中,有关现场实践和试验室试验的试验工作和充填质量问题. | Jianping Li Ernesto Villaescusa Duncan Tyler Terry McGrath 王维德 | 2004 | 矿业研究与开发2004，24，z1： | 2 |
| 8 | Cotton Gh BAK 1 Mediates Verticillium Wilt Resistance and Cell Death显示文摘 | Xiquan Gao Fangjun Li Maoying Li Ali S. Kianinejad Jane K. Dever Terry A. Wheeler Zhaohu Li Ping He Libo Shan | 2013 | J Integr Plant Biol2013，，7： | 2 |
| 9 | Guanylyl Cyclase C Suppresses Intestinal Tumorigenesis by Restricting Proliferation and Maintaining Genomic Integrity显示文摘 | Peng Li Stephanie Schulz Alessandro Bombonati Juan P. Palazzo Terry M. Hyslop Yihuan Xu Amy A. Baran Linda D. Siracusa Giovanni M. Pitari Scott A. Waldman | 2007 | Gastroenterology2007，，2： | 2 |
| 10 | Association between interleukin-21 gene rs907715 polymorphism and gastric precancerous lesions in a Chinese population显示文摘BACKGROUND The single nucleotide polymorphisms of interleukin-21(IL-21)gene were confirmed to be related to various diseases,but no studies have examined the possible role of IL-21 single nucleotide polymorphisms(SNPs)(rs907715,rs2221903,and rs12508721)in gastric precancerous lesions.AIM To explore the associations between SNPs of IL-21 gene(rs907715,rs2221903,and rs12508721)and gastric precancerous lesions in a Chinese population.METHODS Three SNPs of IL-21 were genotyped using polymerase chain reaction–ligase detection reaction in 588 cases and 290 healthy controls from May 2013 to December 2016 in northwestern China.Gastric precancerous lesions were confirmed by endoscopic examination and categorized as non-atrophic gastritis,atrophic gastritis,and intestinal metaplasia.Descriptive statistic and logistic regression were used for data analyses.RESULTS IL-21 rs907715 genotype CC and C frequencies were higher in in patients with gastric precancerous lesions than in the controls(OR=1.59,95%CI:1.06-2.38,P=0.013;OR=1.28,95%CI:1.01-2.22,P=0.044,respectively)after adjusting for confounding factors.For SNP rs907715 in intestinal metaplasia patients,significant differences between cases and controls were observed in the frequencies of genotype CC and C(OR=1.92,95%CI:1.24-2.98,P=0.004;OR=1.53,95%CI:1.04-2.24,P=0.028,respectively);for non-atrophic gastritis and atrophic gastritis patients,the CC and C genotypes showed no significant association with risk in all models.No association between either rs2221903 or rs12508721 and gastric precancerous lesions was found in the present study.In the haplotype analysis,the TC haplotype(rs907715 and rs12508721)and TT haplotype(rs2221903 and rs907715)were more frequent in the case group than control group(P<0.05).CONCLUSION Our findings indicate that SNP rs907715 of IL-21 gene is associated with gastric precancerous lesions.The TC haplotype(rs907715 and rs12508721)and TT haplotype(rs2221903 and rs907715)increased the risk of gastric precancerous lesions.If confirmed,these findings will shed light on the etiology of precancerous lesions. | Xiao-Qin Wang Yang Li Paul D Terry Wen-Jing Kou Yue Zhang Zhao-Zhao Hui Xiao-Han Ren Ming-Xu Wang | 2020 | World Journal of Gastrointestinal Oncology2020，12，3： | 2 |
| 11 | Human-animal interactions and bat coronavirus spillover potential among rural residents in Southern China显示文摘Human interaction with animals has been implicated as a primary risk factor for several high impact zoonoses,including many bat-origin viral diseases.However the animal-to-human spillover events that lead to emerging diseases are rarely observed or clinically examined,and the link between specific interactions and spillover risk is poorly understood.To investigate this phenomenon,we conducted biological-behavioral surveillance among rural residents in Yunnan,Guangxi,and Guangdong districts of Southern China,where we have identified a number of SARS-related coronaviruses in bats.Serum samples were tested for four bat-borne coronaviruses using newly developed enzyme-linked immunosorbent assays(ELISA).Survey data were used to characterize associations between human-animal contact and bat coronavirus spillover risk.A total of 1,596 residents were enrolled in the study from 2015 to 2017.Nine participants(0.6%)tested positive for bat coronaviruses.265(17%)participants reported severe acute respiratory infections(SARI)and/or influenza-like illness(ILI)symptoms in the past year,which were associated with poultry,carnivore,rodent/shrew,or bat contact,with variability by family income and district of residence.This study provides serological evidence of bat coronavirus spillover in rural communities in Southern China.The low seroprevalence observed in this study suggests that bat coronavirus spillover is a rare event.Nonetheless,this study highlights associations between human-animal interaction and zoonotic spillover risk.These findings can be used to support targeted biological behavioral surveillance in high-risk geographic areas in order to reduce the risk of zoonotic disease emergence. | Li Hongying Mendelsohn Emma Zong Chen Zhang Wei Hagan Emily Wang Ning Li Shiyue Yan Hong Huang Huimin Zhu Guangjian Ross Noam Chmura Aleksei Terry Philip Fielder Mark Miller Maureen Shi Zhengli Daszak Peter | 2019 | Biosafety and Health2019，1，2： | 2 |
| 12 | Comparative impulse voltage measurements at the national measurement laboratory (NML) CSIRO australia and the institute for national measurement standarda (INMS) NRC Canada 显示文摘 | Yi Li Juris Rungis Terry R | 2003 | IEEE Transactions on Instrument and Measurement2003，52，2： | 1 |
| 13 | Applications of the GA/KNN Method to SELDI Proteomics Data显示文摘 | Li Leping Umbach D M Terry P | 2004 | Bioinformatics2004，20，10： | 1 |
| 14 | Independent associations of serum concentrations of 25-hydroxyvitamin D and parathyroid hormone with blood pressure among US adults显示文摘 | Guixiang Zhao Earl S Ford Chaoyang Li Penny M Kris-Etherton Terry D Etherton Lina S Balluz | 2010 | Journal of Hypertension2010，，9： | 1 |
| 15 | The spread of the western flow-er thrips Frankliniella occidentalis (Pergande) 显示文摘 | Kirk WDJ Terry LI | 2003 | Agricultural and Forest Entomology2003，5，4： | 1 |
| 16 | Near 1 kW of continuous-wave power from a single high-efficiency diode-laser bar 显示文摘 | LI H X TERRY T IRVING C | 2007 | IEEE Photonics Technology Letters2007，19，13： | 1 |
| 17 | International comparison of a pulse calibrator used in high-voltage impulse calibration显示文摘 | Yi Li Juris Rungis Terry McComb | 2001 | IEEE Trans on Instrumentation and Measurements2001，，5： | 1 |
| 18 | Response to color by male and female Frankliniella occidentalis during swarming and non - swarming behavior 显示文摘 | Matteson N A Terry LI | 1992 | Entomologia Experimentalis et Applicata1992，63，2： | 1 |
| 19 | Postmortem molecular analysis of KCNQ1 , KCNH2 , KCNE1 and KCNE2 genes in sudden unexplained nocturnal death syndrome in the Chinese Han population显示文摘 | Chao Liu Qianhao Zhao Terry Su Shuangbo Tang Guoli Lv Hong Liu Li Quan Jianding Cheng | 2013 | Forensic Science International . 2013 (1-3)2013，，1： | 1 |
| 20 | Colocalisation of Vascular Endothelial Growth Factor and Its Flt-1 Receptor in Human Placenta显示文摘 | Asif Ahmed Xiao F. Li Caroline Dunk Martin J. Whittle D. Ian Rushton Terry Rollason | 1995 | Growth Factors1995，，3： | 1 |
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