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| 1 | Alveolar echinococcosis-spreading disease challenging clinicians: A case report and literature review显示文摘Human alveolar echinococcosis (AE) is a potentially deadly disease; recent studies have shown that the endemic area of Echinococcus multilocularis , its causative agent, is larger than previously known. This disease has low prevalence and remains underreported in Europe. Emerging clinical data show that diagnostic difficulties are still common. We report on a 76-year old patient suffering from AE lesions restricted to the left lobe of the liver who underwent a curative extended left hemihepatectomy. Prior to the resection a liver biopsy under the suspicion of an atypical malignancy was performed. After the intervention he developed a pseudoaneurysm of the hepatic artery that was successfully coiled. Surprisingly, during surgery, the macroscopic appearance of the tumour revealed a growth pattern that was rather typical for cystic echinococcosis (CE), i.e. , a gross tumour composed of multiple large vesicles with several centimeters in diameter. In addition, there were neither extensive adhesions nor infiltrations of the neighboring pancreas and diaphragm as was expected from previous imaging results. The unexpected diagnosis of AE was confirmed by definite histopathology, specific polymerase chain reaction and serology results. This is a rare case of unusual macroscopic presentation of AE that posed immense diagnostic challenges and had an eventful course. To our knowledge this is the first case of an autochthonous infection in this particular geographic area of Germany, the federal state of Saxony. This report may provide new hints for an expanding area of risk for AE and emphasizes the risk of complications in the scope of diagnostic procedures and the limitations of modern radiological imaging. | Georgi Atanasov Christoph Benckert Armin Thelen Dennis Tappe Matthias Frosch Dieter Teichmann Thomas FE Barth Christian Wittekind Stefan Schubert Sven Jonas | 2013 | World Journal of Gastroenterology2013，19，26： | 14 |
| 2 | p53 spreads out further: suppression of EMT and stemness by activating miR-200c expression显示文摘 | Jorg Schubert Thomas Brabletz | 2011 | Cell Research2011，21，5： | 4 |
| 3 | Structure-property relationships in ILs: A study of the alkyl chain length dependence in vaporisation enthalpies of pyridinium based ionic liquids显示文摘The enthalpies of vaporization for the series of pyridinium-based ionic liquids with bis(trifluoromethylsulfonyl)imide anion [CnPy][NTf2] (n = 2, 3, 4, 5, and 6) have been determined with the quartz crystal microbalance technique combined with the Langmuir evaporation. The linear dependence of vaporization enthalpies on the chain length has been revealed. New approach based on volumetric, surface tension, and speed of sound measurements has been developed for estimation of heat capacity differences between gas and liquid phase, which were required for adjustment of measured vaporization enthalpies to the ref- erence temperature 298 K. | ZAITSAU Dzmitry H. YERMALAYEU Andrei V. EMEL'YANENKO Vladimir N. VEREVKIN Sergey P. WELZ-BIERMANN Urs SCHUBERT Thomas | 2012 | Science China Chemistry2012，55，8： | 4 |
| 4 | Endoscopic Transforaminal Discectomy for Recurrent Lumbar Disc Herniation: A Prospective, Cohort Evaluation of 262 Consecutive Cases显示文摘 | Thomas Hoogland Karolien van den Brekel-Dijkstra Michael Schubert Boris Miklitz | 2008 | Spine2008，，9： | 3 |
| 5 | Transforaminal Posterolateral Endoscopic Discectomy With or Without the Combination of a Low-Dose Chymopapain: A Prospective Randomized Study in 280 Consecutive Cases显示文摘 | Thomas Hoogland Michael Schubert Boris Miklitz Agnes Ramirez | 2006 | Spine2006，，24： | 3 |
| 6 | Warm HTK donor pretreatment reduces liver injury during static cold storage in experimental rat liver transplantation显示文摘BACKGROUND: Organ shortage has led to an increased number of transplantations from extended criteria donors. These organs are more vulnerable to ischemia-reperfusion injury. Thus,improvement of organ preservation is needed. HTK is a widely used preservation solution for static cold storage in liver transplantation. The present study was to investigate the beneficial effect of warm HTK donor pretreatment on liver preservation.METHODS: Male inbred Wistar rats(weighing 230-260 g) served as donors and recipients(n=6/group). Donors of treatment groups received i.v. 0.01 m L/g body weight(BW) warm(21 ℃) HTK systemically 15 minutes prior to cold perfusion. Control groups received 0.01 m L/g BW warm(21 ℃) Na Cl 0.9%. Following pretreatment,donors were flushed with 4 ℃ cold HTK,livers were explanted and stored in 4 ℃ HTK for six hours. Thereafter orthotopic liver transplantation was performed. Recipients were harvested four hours,two and five days after reperfusion and blood and liver tissue samples were obtained. Blood samples were analyzed for AST,ALT,lactate dehydrogenase and bilirubin. Liver histological analysis as well as tissue analysis for pro-MMP2,MMP2 and pro-MMP9 using zymography was conducted.RESULTS: Treatment groups showed significantly lower ALT and lactate dehydrogenase levels as well as significantly lower activities of pro-MMP2,MMP2 and pro-MMP9. Histological analysis revealed only minor damage in all groups.CONCLUSIONS: The new concept of warm HTK pretreatment significantly reduced ischemia-reperfusion injury. The reduced ischemia-reperfusion injury was due to MMP inhibition. Warm HTK donor pretreatment is easy to handle and could further improve HTK's potency in liver preservation. | Wenzel Schoening Veeravorn Ariyakhagorn Thomas Schubert Peter Olschewski Andreas Andreou Peter Neuhaus Johann Pratschke Gero Puhl | 2015 | Hepatobiliary & Pancreatic Diseases International2015，14，6： | 2 |
| 7 | A perspective of riverbank filtration显示文摘 | Chittaranjan Ray Thomas Grischek Jurgen Schubert | 2002 | Journal of AWWA2002，94，4： | 1 |
| 8 | Aldehyde dehydrogenase activity among primary leukemia cells is associated with stem cell features and correlates with adverse clinical outcomes显示文摘 | Dan Ran Mario Schubert Larissa Pietsch Isabel Taubert Patrick Wuchter Volker Eckstein Thomas Bruckner Margot Zoeller Anthony D. Ho | 2009 | Experimental Hematology2009，，12： | 1 |
| 9 | A perspective of riverbank filtration显示文摘 | Thomas Grischek Jurgen Schubert | 2002 | Journal of AWWA2002，94，4： | 1 |
| 10 | Hurricane Spiral Bands显示文摘 | THOMAS A Guinn WAYNE H Schubert | 1993 | J Atmos Sci1993，50，20： | 1 |
| 11 | County and Township Cadres as a Strategic Group. A New Approach to Political Agency in China’s Local State显示文摘 | Thomas Heberer Gunter Schubert | 2012 | Journal of Chinese Political Science2012，，3： | 1 |
| 12 | Downstream changes in phytoplankton composition and biomass in a lowland river–lake system (Warnow River, Germany)显示文摘 | Mandy Bahnwart Thomas Hübener Hendrik Schubert | | Hydrobiologia (-)0，，： | 1 |
| 13 | A perspective of riverbank filtration 显示文摘 | Chittaranjan Ray Thomas Grischek Jurgen Schubert | 2002 | Journal of AWWA2002，，4： | 1 |
| 14 | Experimental Lung Transplantation: Impact of Preservation Solution and Route of Delivery显示文摘 | Thorsten Wittwer Ulrich F.W. Franke Antonia Fehrenbach Matthias Ochs Tim Sandhaus Alex Schuette Stefan Richter Niels Dreyer Lars Knudsen Thomas Müller Harald Schubert Joachim Richter Thorsten Wahlers | 2005 | Journal of Heart and Lung Transplantation2005，，8： | 1 |
| 15 | Extended Query Refinement for Medical Image Retrieval显示文摘 | Thomas M. Deserno Ph. D. Mark O. Güld Bartosz Plodowski Klaus Spitzer Berthold B. Wein Henning Schubert Hermann Ney Thomas Seidl | 2008 | Journal of Digital Imaging2008，，3： | 1 |
| 16 | Functional implication of Netrin expression in malignant melanoma显示文摘 | Simone Kaufmann Silke Kuphal Thomas Schubert Anja K. Bosserhoff | 2009 | Cellular Oncology2009，，6： | 1 |
| 17 | A ease of vir- ilization induced by a KI'ukenberg tumor from gastric cancer 显示文摘 | Homung Matthias Vogel Peter Schubert Thomas | 2008 | World Journal of Surgical Oncology2008，6，： | 1 |
| 18 | A perspective of riverbank filtration显示文摘 | Chittaranjan Ray Thomas Grischek Jurgen Schubert | 2002 | Journal of AWWA2002，，4： | 1 |
| 19 | A perspective of riverbank filtration 显示文摘 | Chittaranjan Ray Thomas Grischek Jurgen Schubert | 2002 | Applied Science and Tech Plus2002，，： | 1 |
| 20 | Experimental Lung Transplantation: Impact of Preservation Solution and Route of Delivery显示文摘 | Thorsten Wittwer Ulrich F.W. Franke Antonia Fehrenbach Matthias Ochs Tim Sandhaus Alex Schuette Stefan Richter Niels Dreyer Lars Knudsen Thomas Müller Harald Schubert Joachim Richter Thorsten Wahlers | 2005 | Journal of Heart and Lung Transplantation2005，，8： | 1 |
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