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| 1 | High-Efficiency Reduction of Rice Amylose Content via CRISPR/Cas9-Mediated Base Editing显示文摘Rice is a staple food for more than half of the human population.It has been estimated that by 2030,rice production must increase by 40%to meet the growing demand(Khush,2005).In addition,with the improvement of people's living standards,the demand for elite rice with better eating and cooking quality(ECQ)is increasing.ECQ is determined by several factors,including amylose content(AC),gel consistency(GC),gelatinization temperature(GT)and viscosity,where AC is the predominant factor(Juliano,1998). | Li He Li Xiufeng Xu Yang Liu Hualong He Mingliang Tian Xiaojie Wang Zhenyu Wu Xiuju Bu Qingyun Yang Jie | 2020 | Rice science2020，27，6： | 7 |
| 2 | Global methane and nitrous oxide emissions from terrestrial ecosystems due to multiple environmental changes显示文摘Greenhouse gas(GHG)-induced climate change is among the most pressing sustainability challenges facing humanity today,posing serious risks for ecosystem health.Methane(CH_(4))and nitrous oxide(N_(2)O)are the two most important GHGs after carbon dioxide(CO_(2)),but their regional and global budgets are not well known.In this study,we applied a process-based coupled biogeochemical model to concurrently estimate the magnitude and spatial and temporal patterns of CH_(4)and N_(2)O fluxes as driven by multiple environmental changes,including climate variability,rising atmospheric CO_(2),increasing nitrogen deposition,tropospheric ozone pollution,land use change,and nitrogen fertilizer use.The estimated CH_(4)and N_(2)O emissions from global land ecosystems during 1981-2010 were 144.39±12.90 Tg C/yr(mean 62 SE;1 Tg=1012 g)and 12.52±0.74 Tg N/yr,respectively.Our simulations indicated a significant(P,0.01)annually increasing trend for CH_(4)(0.43±0.06 Tg C/yr)and N_(2)O(0.14±0.02 Tg N/yr)in the study period.CH_(4)and N_(2)O emissions increased significantly in most climatic zones and continents,especially in the tropical regions and Asia.The most rapid increase in CH_(4)emission was found in natural wetlands and rice fields due to increased rice cultivation area and climate warming.N_(2)O emission increased substantially in all the biome types and the largest increase occurred in upland crops due to increasing air temperature and nitrogen fertilizer use.Clearly,the three major GHGs(CH_(4),N_(2)O,and CO_(2))should be simultaneously considered when evaluating if a policy is effective to mitigate climate change. | Hanqin Tian Guangsheng Chen Chaoqun Lu Xiaofeng Xu Wei Ren Bowen Zhang Kamaljit Banger Bo Tao Shufen Pan Mingliang Liu Chi Zhang Lori Bruhwiler Steven Wofsy | 2015 | Ecosystem Health and Sustainability2015，1，1： | 7 |
| 3 | Entanglement in spin-1 Heisenberg XY chain显示文摘We investigated the quantum entanglement in spin-1 Heisenberg XY chain for two-spin-qutrit and multi-particle systems. As a measure of the entanglement, the negativity of this state was analyzed as a function of the temperature and the magnetic field. We gave some numerical results and discussed them in detail. We found that the negativity increases monotonously with the coupling constants |J1| and |J2|, and it showed a symmetry with respect to the point of J1=0 and J2=0. In addition to the above features, there is evidence that the critical temperature is independent of the length of the chain. | QIN Meng TAO YingJuan HU MingLiang TIAN DongPing | 2008 | Science China(Physics,Mechanics & Astronomy)2008，51，7： | 6 |
| 4 | OsMKKK70 regulates grain size and leaf angle in rice through the OsMKK4-OsMAPK6-OsWRKY53 signaling pathway显示文摘Grain size and leaf angle are key agronomic traits that determine final yields in rice.However,the underlying molecular mechanisms are not well understood.Here we demonstrate that the Oryza sativa Mitogen Activated Protein Kinase Kinase Kinase OsMKKK70 regulates grain size and leaf angle in rice.Overexpressing OsMKKK70 caused plants to produce longer seeds.The osmkkk62/70 double mutant and the osmkkk55/62/70 triple mutant displayed significantly smaller seeds and a more erect leaf angle compared to the wild type,indicating that OsMKKK70 functions redundantly with its homologs Os MKKK62 and Os MKKK55.Biochemical analysis demonstrated that OsMKKK70 is an active kinase and that OsMKKK70 interacts with Os MKK4 and promotes Os MAPK6 phosphorylation.In addition,the osmkkk62/70 double mutant showed reduced sensitivity to Brassinosteroids(BRs).Finally,overexpressing constitutively active Os MKK4,Os MAPK6,and Os WRKY53 can partially complement the smaller seed size,erect leaf,and BR hyposensitivity of the osmkkk62/70 double mutant.Taken together,these findings suggest that OsMKKK70 might regulate grain size and leaf angle in rice by activating Os MAPK6 and that OsMKKK70,Os MKK4,Os MAPK6,and Os WRKY53 function in a common signaling pathway that controls grain shape and leaf angle. | Zhiqi Liu Enyang Mei Xiaojie Tian Mingliang He Jiaqi Tang Min Xu Jiali Liu Lu Song Xiufeng Li Zhenyu Wang Qingjie Guan Qijiang Xu Qingyun Bu | 2021 | Journal of Integrative Plant Biology2021，63，12： | 6 |
| 5 | Oryza sativa mediator subunit OsMED25 interacts with OsBZR1 to regulate brassinosteroid signaling and plant architecture in rice显示文摘Brassinosteroids(BRs)are plant-specific steroid hormones which regulate plant growth,development,and adaptation.Transcriptional regulation plays key roles in plant hormone signaling.A mediator can serve as a bridge between gene-specific transcription factors and the RNA polymerase machinery,functioning as an essential component in regulating the transcriptional process.However,whether a mediator is involved in BR signaling is unknown.Here,we discovered that Oryza sativa mediator subunit 25(Os MED25)is an important regulator of rice BR signaling.Phenotypic analyses showed that the Os MED25-RNAi and osmed25 mutant presented erect leaves,as observed in BR-deficient mutants.In addition,the Os MED25-RNAi and osmed25 mutant exhibited decreased BR sensitivity.Genetic analysis indicated that Os MED25-RNAi could suppress the enhanced BR signaling phenotype of Osbzr1-D.Further biochemical analysis showed that Os MED25 interacts with Os BZR1 in vivo,and Os MED25 is enriched on the promoter of Os BZR1 target genes.RNA sequencing analysis indicated that Os MED25 affects the expression of approximately 45%of Os BZR1-regulated genes and mainly functions as a corepressor of Os BZR1.Together,these findings revealed that Os MED25 regulates rice BR signaling by interacting with Os BZR1 and modulating the expression of Os BZR1 target genes,thus expanding our understanding of the roles of mediators in plant hormone signaling. | Yuekun Ren Xiaojie Tian Shuyu Li Enyang Mei Mingliang He Jiaqi Tang Min Xu Xiufeng Li Zhenyu Wang Chuanyou Li Qingyun Bu | 2020 | Journal of Integrative Plant Biology2020，62，6： | 3 |
| 6 | Two-dimensional characterization of three-dimensional magnetic bubbles in Fe_(3)Sn_(2) nanostructures显示文摘We report differential phase contrast scanning transmission electron microscopy(TEM) of nanoscale magnetic objects in Kagome ferromagnet Fe_(3)Sn_(2) nanostructures. This technique can directly detect the deflection angle of a focused electron beam, thus allowing clear identification of the real magnetic structures of two magnetic objects including three-ring and complex arch-shaped vortices in Fe_(3)Sn_(2) by Lorentz-TEM imaging. Numerical calculations based on real material-specific parameters well reproduced the experimental results, showing that the magnetic objects can be attributed to integral magnetizations of two types of complex three-dimensional(3D) magnetic bubbles with depth-modulated spin twisting. Magnetic configurations obtained using the high-resolution TEM are generally considered as two-dimensional(2D)magnetic objects previously. Our results imply the importance of the integral magnetizations of underestimated 3D magnetic structures in 2D TEM magnetic characterizations. | Jin Tang Yaodong Wu Lingyao Kong Weiwei Wang Yutao Chen Yihao Wang Y.Soh Yimin Xiong Mingliang Tian Haifeng Du | 2021 | National Science Review2021，8，6： | 2 |
| 7 | NUPR1 promotes the proliferation and metastasis of oral squamous cell carcinoma cells by activating TFE3-dependent autophagy显示文摘Oral squamous cell carcinoma(OSCC)is the most common type of oral malignancy,and metastasis accounts for the poor prognosis of OSCC.Autophagy is considered to facilitate OSCC development by mitigating various cellular stresses;nevertheless,the mechanisms of autophagy in OSCC cell proliferation and metastasis remain unknown.In our study,high-sensitivity label-free quantitative proteomics analysis revealed nuclear protein 1(NUPR1)as the most significantly upregulated protein in formalin-fixed paraffin-embedded tumour samples derived from OSCC patients with or without lymphatic metastasis. | Tengfei Fan Xiaoning Wang Sheng Zhang Ping Deng Yi Jiang Yidan Liang Sheng Jie Qing Wang Chuwen Li Guocai Tian Zhen Zhang Zhenhu Ren Bo Li Yanrong Chen Zhijing He Yan Luo Mingliang Chen Hanjiang Wu Zhengping Yu Huifeng Pi Zhou Zhou Zhiyuan Zhang | 2022 | Signal Transduction and Targeted Therapy2022，7，5： | 2 |
| 8 | Spatial and temporal patterns of China’s cropland during 1990–2000: An analysis based on Landsat TM data显示文摘 | Jiyuan Liu Mingliang Liu Hanqin Tian Dafang Zhuang Zengxiang Zhang Wen Zhang Xianming Tang Xiangzheng Deng | 2005 | Remote Sensing of Environment2005，，4： | 2 |
| 9 | bZIP71 delays flowering by suppressing Ehd1 expression in rice显示文摘Flowering time is a fundamental factor determining the global distribution and final yield of rice(Oryza sativa).Although diverse flowering time genes have been reported in this crop,the transcriptional regulation of its key flowering genes are poorly understood.Here,we report that a basic leucine zipper transcription factor,bZIP71,functions as a flowering repressor.The overexpression of bZIP71 delays flowering,while the bzip71 mutant flowers early in both long-day and short-day conditions.A genetic analysis showed that the regulation of flowering by bZIP71 might be independent of Heading date 2(Hd2),Hd4,and Hd5.Importantly,bZIP71 directly associates with the Early heading date 1(Ehd1)promoter and represses its transcription,and genetically the function of bZIP71 is impaired in the ehd1 mutant.Moreover,bZIP71 interacts with major components of polycomb repressive complex 2(PRC2),SET domain group protein 711(SDG711),and Fertilization independent endosperm 2(FIE2),through which bZIP71 regulates the H3K27me3 level of Ehd1.Taken together,we present a transcriptional regulatory mechanism in which bZIP71 enhances the H3K27me3 level of Ehd1 and transcriptionally represses its expression,which not only offers a novel insight into a flowering pathway,but also provides a valuable putative target for the genetic engineering and breeding of elite rice cultivars. | Xiufeng Li Xiaojie Tian Mingliang He Xinxin Liu Zhiyong Li Jiaqi Tang Enyang Mei Min Xu Yingxiang Liu Zhenyu Wang Qingjie Guan Wei Meng Jun Fang Jian Zhang Qingyun Bu | 2022 | Journal of Integrative Plant Biology2022，64，7： | 2 |
| 10 | Spatial and temporal patterns of China' s cropland during 1990-2000: An analysis based on Landsat TM data显示文摘 | Liu Jiyuan Liu Mingliang Tian Hanqin | 2005 | Remote Sensing of Environment2005，98，： | 1 |
| 11 | Low-bandgap conjugated polymers based on benzodipyrrolidone with reliable unipolar electron mobility exceeding 1 cm^(2) V^(-1)s^(-1)显示文摘The employment of an intrinsic quinoidal building block,benzodipyrrolidone(BDP),on constructing conjugated polymers(PBDP-2F and PBDP-2CN)with high electron mobility and unipolar transport characteristic in polyethylenimine ethoxylated(PEIE)modified organic field-effect transistors(OFETs)is reported.The intrinsic quinoidal characteristic and excellent coplanarity of BDP can lower the lowest unoccupied molecular orbital(LUMO)levels and improve ordered interchain packing of the resulting polymers in solid states,which are favorable for electron-injection and transport.By using PEIE as the interlayer to block the hole injection,unipolar n-type transport characteristics with high electron mobility of 0.58 and 1.01 cm^(2) V^(-1)s^(-1)were achieved by the OFETs based on PBDP-2F and PBDP-2CN,respectively.More importantly,the extracted mobilities are highly reliable with the reliability factor of above 80%.To the best of our knowledge,PBDP-2CN is the very first quinoid-based conjugated polymer with reliable electron mobility exceeding 1 cm^(2) V^(-1)s^(-1).This work represents a significant step in exploring intrinsic quinoidal CPs for application in n-channel OFETs and logic complementary circuits. | Mingqun Yang Tian Du Xuxia Zhao Xuelong Huang Langheng Pan Shuting Pang Haoran Tang Zhongxiang Peng Long Ye Yunfeng Deng Mingliang Sun Chunhui Duan Fei Huang Yong Cao | 2021 | Science China Chemistry2021，64，7： | 1 |
| 12 | Spatial and temporal patterns of China's cropland during 1990-2000 :An analysis based on landsat TM data显示文摘 | Liu Jiyuan Liu Mingliang Tian Hanqin | 2005 | Remote Sensing of Enviroment2005，98，： | 1 |
| 13 | Microtwinning in Template-Synthesized Single-crystal Metal Nanowires显示文摘 | Mingliang Tian Thomas E M el al | 2004 | Journal of Physical Chemistry B2004，108，3： | 1 |
| 14 | Network eontrolled teleportation of N-qubit state显示文摘 | Chen Wenxue Tian Xiulao Hu Mingliang | 2010 | Journal of Modern Opties2010，57，17： | 1 |
| 15 | Log-periodic quantum magneto-oscillations and discrete-scale invariance in topological material HfTe5显示文摘Discrete-scale invariance(DSI)is a phenomenon featuring intriguing log-periodicity that can be rarely observed in quantum systems.Here,we report the log-periodic quantum oscillations in the longitudinal magnetoresistivity(ρxx)and the Hall traces(ρyx)of Hf Te5 crystals,which reveal the DSI in the transport-coefficients matrix.The oscillations inρxx andρyx show the consistent log B-periodicity with a phase shift.The finding of the log B oscillations in the Hall resistance supports the physical mechanism as a general quantum effect originating from the resonant scattering.Combined with theoretical simulations,we further clarify the origin of the log-periodic oscillations and the DSI in the topological materials.This work evidences the universality of the DSI in the Dirac materials and provides indispensable information for a full understanding of this novel phenomenon. | Huichao Wang Yanzhao Liu Yongjie Liu Chuanying Xi Junfeng Wang Jun Liu Yong Wang Liang Li Shu Ping Lau Mingliang Tian Jiaqiang Yan David Mandrus Ji-Yan Dai Haiwen Liu Xincheng Xie Jian Wang | 2019 | National Science Review2019，6，5： | 1 |
| 16 | Nanometer-scale Modification and Welding of Silicbn and Metallic Nanowires with a High-in- tensity Electron Beam 显示文摘 | Xu Shengyong Tian Mingliang Wang Jinguo | 2005 | Small2005，1，12： | 1 |
| 17 | Effects of multiple environment stresses on evapotranspiration and runoff over eastern China 显示文摘 | Mingliang Liu Hanqin Tian Chaoqun Lu | 2012 | Journal of Hydrology2012，，： | 1 |
| 18 | Spatial and Temporal Patterns of China's Cropland during 1990-2000:An Analysis Based on Landsat TM data显示文摘 | Liu Jiyuan Liu Mingliang Tian Hanqin | 2005 | Remote Sensing of Environment2005，，98： | 1 |
| 19 | Relationship Between Zooplankton Community Characteristics and Environmental Conditions in the Surface Waters of the Western Pacific Ocean During the Winter of 2014显示文摘Understanding the effects of environmental heterogeneity on zooplankton communities has been a hot topic for several decades.However,relatively little is known about the responses of zooplankton communities to environmental conditions at large scales from inshore waters to the open ocean.Here,we used the abundance,biovolume,taxa and size spectra of zooplankton col-lected from the surface waters of the western Pacific Ocean during the winter of 2014 to study the relationship between zooplankton community characteristics and environmental conditions using multiple linear regression(MLR)analysis and redundancy analysis(RDA).According to a hierarchical cluster analysis based on hydrographic conditions,the study area was classified into five water masses.Significant correlations were identified between the limited nutrients and the zooplankton abundance and biovolume from inshore waters to the open ocean.Non-metric multidimensional scaling(NMDS)revealed two distinct zooplankton assemblages.In the northern inshore,Copepoda and Euphausiacea were the dominant zooplankton taxa and in other water masses,Chaetognatha and gelatinous zooplankton were the dominant zooplankton taxa in addition to Copepoda.Our results suggested that,on a large scale from inshore waters to the open ocean in the western Pacific Ocean,the spatial distribution of zooplankton taxa was mainly influ-enced by environmental conditions,while in the inshore waters,it was due to the top-down effect of the dominant zooplankton taxa.Finally,the slope of the normalized biovolume size spectra(NBSS)was negatively correlated with chlorophyll-a(Chl-a)concentra-tion and PO_(4)^(3−)-P concentration in the inshore waters,which indicated that the higher the trophic level the dominant zooplankton taxa were,the steeper the NBSS slope was. | TIAN Ziyang ZHENG Shan GUO Shujin ZHU Mingliang LIANG Junhua DU Juan SUN Xiaoxia | 2021 | Journal of Ocean University of China2021，20，3： | 1 |
| 20 | Biomineralization inspired 3D printed bioactive glass nanocomposite scaffolds orchestrate diabetic bone regeneration by remodeling micromilieu显示文摘TypeⅡdiabetes mellitus(TIIDM)remains a challenging clinical issue for both dentists and orthopedists.By virtue of persistent hyperglycemia and altered host metabolism,the pathologic diabetic micromilieu with chronic inflammation,advanced glycation end products accumulation,and attenuated biomineralization severely impairs bone regeneration efficiency.Aiming to“remodel”the pathologic diabetic micromilieu,we 3D-printed bioscaffolds composed of Sr-containing mesoporous bioactive glass nanoparticles(Sr-MBGNs)and gelatin methacrylate(GelMA).Sr-MBGNs act as a biomineralization precursor embedded in the GelMA-simulated extracellular matrix and release Sr,Ca,and Si ions enhancing osteogenic,angiogenic,and immunomodulatory properties.In addition to angiogenic and anti-inflammatory outcomes,this innovative design reveals that the nanocomposites can modulate extracellular matrix reconstruction and simulate biomineralization by activating lysyl oxidase to form healthy enzymatic crosslinked collagen,promoting cell focal adhesion,modulating osteoblast differentiation,and boosting the release of OCN,the noncollagenous proteins(intrafibrillar mineralization dependent),and thus orchestrating osteogenesis through the Kindlin-2/PTH1R/OCN axis.This 3D-printed bioscaffold provides a multifunctional biomineralization-inspired system that remodels the“barren”diabetic microenvironment and sheds light on the new bone regeneration approaches for TIIDM. | Zeqian Xu Xuanyu Qi Minyue Bao Tian Zhou Junfeng Shi Zhiyan Xu Mingliang Zhou Aldo R.Boccaccini Kai Zheng Xinquan Jiang | 2023 | Bioactive Materials2023，，7： | 1 |
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