|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Ginsenoside Rh2 inhibits proliferation and induces apoptosis in human leukemia cells via TNF-~ signaling pathway显示文摘人参皂甙 Rh2,从人参属人参提取的 triterpene saponin,对多重癌症的展览药理学活动。然而,人参皂甙 Rh2 的 anticancer 机制是不清楚的。在这研究,我们发现人参皂甙 Rh2 有效地禁止生长并且导致 HL-60 房间的 apoptosis。用 microarray 技术,我们发现了那个肿瘤坏死因素 --(TNF-) 清楚地是起来调整的。而且, anti-TNF- 抗体经由 caspase-8, caspase-9,和 caspase-3 激活的抑制减轻了导致 Rh2 的 HL-60 房间 apoptosis。另外, TNF- 起来规定也在另外的对待 Rh2 的癌症房间线被观察。这些结果证明 TNF- 在人参皂甙起一个关键作用导致 Rh2 的房间 apoptosis。 | Jingjia Huang Kunjian Peng Linghao Wang Bin Wen Lin Zhou Tiao Luo Min Su Jijia Li Zhiyong Luo | 2016 | Acta Biochimica et Biophysica Sinica2016，48，8： | 11 |
| 2 | Low-intensity pulsed ultrasound therapy: a potential strategy to stimulate tendon-bone junction healing显示文摘Incorporation of a tendon graft within the bone tunnel represents a challenging clinical problem. Successfulanterior cruciate ligament (ACL) reconstruction requires solid healing of the tendon graft in the bone tunnel. En-hancement of graft healing to bone is important to facilitate early aggressive rehabilitation and a rapid return topre-injury activity levels. No convenient, effective or inexpensive procedures exist to enhance tendon-bone (T-B)healing after surgery. Low-intensity pulsed ultrasound (LIPUS) improves local blood perfusion and angiogenesis,stimulates cartilage maturation, enhances differentiation and proliferation of osteoblasts, and motivates osteogenic differentiation of mesenchymal stem cells (MSCs), and therefore, appears to be a potential non-invasive tool for T-Bhealing in early stage of rehabilitation of ACL reconstruction. It is conceivable that LIPUS could be used to stimulateT-B tunnel healing in the home, with the aim of accelerating rehabilitation and an earlier return to normal activities inthe near future. The purpose of this review is to demonstrate how LIPUS stimulates T-B healing at the cellular andmolecular levels, describe studies in animal models, and provide a future direction for research. | Zhi-min YING Tiao LIN Shi-gui YAN | 2012 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2012，13，12： | 7 |
| 3 | Comparison of minimally invasive surgery and mini-incision technique for total hip arthroplasty: a sub-group meta-analysis显示文摘背景为全部的新潮的关节造形术( THA )的最低限度地侵略的外科( MIS )应该与更少或没有肌肉损坏结合并且与微型切口技术不同,这很好被接受, MIS 应该比当前的分析的微型切口 surgery.The 目的是把明确地定义的亚群分析用于的有更好的结果证实这个假设是否是 true.Methods 计算机化的文学搜索被使用有关 MIS 或微型切口 THAs.A | ZHAO Xiang LIN Tiao CAI Xun-zi YAN Shi-gui | 2011 | Chinese Medical Journal2011，，24： | 3 |
| 4 | Dexamethasone Decreases Cholestatic Liver Injury Via Inhibition of Intrinsic Pathway with Simultaneous Enhancement of Mitochondrial Biogenesis显示文摘 | Tiao M M Lin T K Chert J B | 2011 | Steroids2011，76，7： | 1 |
| 5 | Mitochondrial DNA Coding and Control Region Variants as Genetic Risk Factors for Type 2 Diabetes显示文摘 | Chia-Wei Liou Jin-Bor Chen Mao-Meng Tiao Shao-Wen Weng Tiao-Lai Huang Jiin-Haur Chuang Shang-Der Chen Yao-Chung Chuang Wen-Chin Lee Tsu-Kung Lin Pei-Wen Wang | 2012 | Diabetes2012，，10： | 1 |
| 6 | Epidermal Growth Factor Receptor (EGFR) Signaling Regulates Epiphyseal Cartilage Development through β-Catenin-dependent and -independent Pathways显示文摘 | Xianrong Zhang Ji Zhu Yumei Li Tiao Lin Valerie A. Siclari Abhishek Chandra Elena M. Candela Eiki Koyama Motomi Enomoto-Iwamoto Ling Qin | 2013 | Journal of Biological Chemistry2013，，45： | 1 |
| 7 | A comprehensive study of long-term skeletal changes after spinal cord injury in adult rats显示文摘Spinal cord injury(SCI)-induced bone loss represents the most severe osteoporosis with no effective treatment.Past animal studies have focused primarily on long bones at the acute stage using adolescent rodents. To mimic chronic SCI in human patients, we performed a comprehensive analysis of long-term structural and mechanical changes in axial and appendicular bones in adult rats after SCI. In this experiment, 4-month-old Fischer 344 male rats received a clinically relevant T13 contusion injury. Sixteen weeks later, sublesional femurs, tibiae,and L4 vertebrae, supralesional humeri, and blood were collected from these rats and additional non-surgery rats for micro-computed tomography(m CT), micro-finite element, histology, and serum biochemical analyses.At trabecular sites, extreme losses of bone structure and mechanical competence were detected in the metaphysis of sublesional long bones after SCI, while the subchondral part of the same bones showed much milder damage. Marked reductions in bone mass and strength were also observed in sublesional L4 vertebrae but not in supralesional humeri. At cortical sites, SCI induced structural and strength damage in both sub- and supralesional long bones. These changes were accompanied by diminished osteoblast number and activity and increased osteoclast number and activity. Taken together, our study revealed site-specific effects of SCI on bone and demonstrated sustained inhibition of bone formation and elevation of bone resorption at the chronic stage of SCI. | Tiao Lin Wei Tong Abhishek Chandra Shao-Yun Hsu Haoruo Jia Ji Zhu Wei-Ju Tseng Michael A Levine Yejia Zhang Shi-Gui Yan X Sherry Liu Dongming Sun Wise Young Ling Qin | 2015 | Bone Research2015，3，3： | 1 |
| 8 | A Genetic Screen Identifies Interferon-α Effector Genes Required to Suppress Hepatitis C Virus Replication显示文摘 | Dahlene N. Fusco Cynthia Brisac Sinu P. John Yi–Wen Huang Christopher R. Chin Tiao Xie Hong Zhao Nikolaus Jilg Leiliang Zhang Stephane Chevaliez Daniel Wambua Wenyu Lin Lee Peng Raymond T. Chung Abraham L. Brass | 2013 | Gastroenterology2013，，7： | 1 |
| 9 | Mixed bacterial-fungal infection following total hip arthroplasty: A case report显示文摘Prosthetic infection is one of the severe postoperative complications of arthroplasty.Mixed bacterial-fungal prosthetic infection is rare but can be disastrous.This case was a 76-year-old female suffered from prosthetic infection following total hip replacement due to femoral neck fracture and underwent multiple debridements.The culture of periprosthetic tissue was bacteriologically sterile following the first debridement,while the Staphylococcus hominis was identified in the second debridement in the previous hospitalization where fungal infection had not been considered.Thus the pathogen spectrum of anti-infection therapy failed to contain fungus.Ultimately,the culture result of our sampled periprosthetic tissue during the third debridement was Candida albicans without bacterium in our hospital.The fungal prosthetic infection was successfully treated by a two-stage revision with antifungal drugs.Accurate diagnosis and standardized treatment is the key to the therapy of infection after hip arthroplasty,especially for mixed bacterial-fungal prosthetic infection. | Yang-Jing Lin Tiao Su Liu Yang Guang-Xing Chen | 2022 | Chinese Journal of Traumatology2022，25，1： | 1 |
| 10 | Early transcriptional deregulation of hepatic mitochondrial biogenesis and its consequent effects on murine cholestatie liver injury显示文摘 | Tiao MM Lin TK Liou CW | 2009 | Apoptosis2009，14，7： | 1 |
| 11 | Early transcriptional deregulation of hepatic mitochondrial biogenesis and its consequent effects on murine cholestatic liver injury显示文摘 | Tiao MM Lin TK Liou CW | 2009 | Apoptosis2009，14，7： | 1 |
| 12 | Survey of Depression by Beck Depression Inventory in Uremic Patients Undergoing Hemodialysis and Hemodiafiltration显示文摘 | Shu‐Fen Su Hwee‐Yeong Ng Tiao‐Lai Huang Po‐Jui Chi Yueh‐Ting Lee Chun‐Ren Lai Yau‐Hsing Lin Pei‐Chen Huang Chien‐Te Lee | 2012 | Therapeutic Apheresis and Dialysis2012，，6： | 1 |
| 13 | Preliminary result of the grass-tree system for rehabilitation of severely eroded red soils显示文摘 | Lin Kaiwang Tiao Xiao | 1998 | Advanced in Geoecology1998，，31： | 1 |
| 14 | Preliminary result of the grass-tree system for rehabilitation of severely eroded red soils显示文摘 | LIN K W TIAO X | 1998 | Advances in Geoecology1998，，31： | 1 |
| 15 | Discontinuous polyostotic fibrous dysplasia with multiple systemic disorders and unique genetic mutations:A case report显示文摘BACKGROUND Polyostotic fibrous dysplasia(PFD)is an uncommon developmental bone disease in which normal bone and marrow are replaced by pseudotumoral tissue.The etiology of PFD is unclear,but it is generally thought to be caused by sporadic,post-zygotic mutations in the GNAS gene.Herein,we report the case of a young female with bone pain and lesions consistent with PFD,unique physical findings,and gene mutations.CASE SUMMARY A 27-year-old female presented with unbearable bone pain in her left foot for 4 years.Multiple bone lesions were detected by radiographic examinations,and a diagnosis of PFD was made after a biopsy of her left calcaneus with symptoms including pre-axial polydactyly on her left hand and severe ophthalmological problems such as high myopia,vitreous opacity,and choroidal atrophy.Her serum cortisol level was high,consistent with Cushing syndrome.Due to consanguineous marriage of her grandparents,boosted whole exome screening was performed to identify gene mutations.The results revealed mutations in HSPG2 and RIMS1,which may be contributing factors to her unique findings.CONCLUSION The unique findings in this patient with PFD may be related to mutations in the HSPG2 and RIMS1 genes. | Tiao Lin Xin-Yu Li Chang-Ye Zou Wei-Wei Liu Jun-Fan Lin Xin-Xin Zhang Si-Qi Zhao Xian-Biao Xie Gang Huang Jun-Qiang Yin Jing-Nan Shen | 2020 | World Journal of Clinical Cases2020，8，23： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员