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| 1 | Dengue Fever Epidemiological Status and Relationship with Meteorological Variables in Guangzhou, Southern China, 2007-2012显示文摘Ecological methodology plus negative binomial regression were used to identify dengue fever(DF)epidemiological status and its relationship with meteorological variables.From 2007 to 2012,annual incidence rate of DF in Guangzhou was 0.33,0.11,0.15,0.64,0.45,and 1.34(per 100 000)respectively,showing an increasing trend.Each 1°C rise of temperature corresponded to an increase of10.23%(95%CI 7.68%to 12.83%)in the monthly number of DF cases,whereas 1 hPa rise of atmospheric pressure corresponded to a decrease in the number of cases by 5.14%(95%CI:7.10%-3.14%).Likewise,each one meter per | LI Tie Gang YANG Zhi Cong LUO Lei DI Biao WANG Ming | 2013 | Biomedical and Environmental Sciences2013，26，12： | 12 |
| 2 | Simulating hydrological responses to climate change using dynamic and statistical downscaling methods: a case study in the Kaidu River Basin, Xinjiang, China显示文摘Climate change may affect water resources by altering various processes in natural ecosystems. Dynamic and statistical downscaling methods are commonly used to assess the impacts of climate change on water resources. Objectively, both methods have their own advantages and disadvantages. In the present study, we assessed the impacts of climate change on water resources during the future periods (2020–2029 and 2040–2049) in the upper reaches of the Kaidu River Basin, Xinjiang, China, and discussed the uncertainties in the research processes by integrating dynamic and statistical downscaling methods (regional climate models (RCMs) and general circulation modes (GCMs)) and utilizing these outputs. The reference period for this study is 1990–1999. The climate change trend is represented by three bias-corrected RCMs (i.e., Hadley Centre Global Environmental Model version 3 regional climate model (HadGEM3-RA), Regional Climate Model version 4 (RegCM4), and Seoul National University Meso-scale Model version 5 (SUN-MM5)) and an ensemble of GCMs on the basis of delta change method under two future scenarios (RCP4.5 and RCP8.5). We applied the hydrological SWAT (Soil and Water Assessment Tool) model which uses the RCMs/GCMs outputs as input to analyze the impacts of climate change on the stream flow and peak flow of the upper reaches of the Kaidu River Basin. The simulation of climate factors under future scenarios indicates that both temperature and precipitation in the study area will increase in the future compared with the reference period, with the largest increase of annual mean temperature and largest percentage increase of mean annual precipitation being of 2.4°C and 38.4%, respectively. Based on the results from bias correction of climate model outputs, we conclude that the accuracy of RCM (regional climate model) simulation is much better for temperature than for precipitation. The percentage increase in precipitation simulated by the three RCMs is generally higher than that simulated by the ensemble of GCMs. As for the changes in seasonal precipitation, RCMs exhibit a large percentage increase in seasonal precipitation in the wet season, while the ensemble of GCMs shows a large percentage increase in the dry season. Most of the hydrological simulations indicate that the total stream flow will decrease in the future due to the increase of evaporation, and the maximum percentage decrease can reach up to 22.3%. The possibility of peak flow increasing in the future is expected to higher than 99%. These results indicate that less water is likely to be available in the upper reaches of the Kaidu River Basin in the future, and that the temporal distribution of flow may become more concentrated. | BA Wulong DU Pengfei LIU Tie BAO Anming LUO Min Mujtaba HASSAN QIN Chengxin | 2018 | Journal of Arid Land2018，10，6： | 8 |
| 3 | Purification and Characterization of a Novel Tetradecapeptide from Ginseng Polypeptides with Enhancing Memory Activity for Mice显示文摘 | LUO Hao-ming JIANG Rui-zhi YANG Xiao-hong CHEN Ying-hong HONG Tie WANG Ying | 2013 | Chemical Research in Chinese Universities2013，29，4： | 6 |
| 4 | Active digital spoof plasmonics显示文摘Digital coding and digital modulation are the foundation of modern information science.The combination of digital technology with metamaterials provides a powerful scheme for spatial and temporal controls of electromagnetic waves.Such a technique,however,has thus far been limited to the control of free-space light.Its application to plasmonics to shape subwavelength fields still remains elusive.Here,we report the design and experimental realization of a tunable conformal plasmonic metasurface;which is capable of digitally coding and modulating designer surface plasmons at the deep-subwavelength scale.Based on dynamical switching between two discrete dispersion states in a controlled manner;we achieve digital modulations ofboth amplitude and phase of surface waves with nearly 100%modulation depth on a single device.Our study not only introduces a new approach for active dispersion engineering,but also constitutes an important step towards the realization of subwavelength integrated plasmonic circuits. | Hao Chi Zhang Tie Jun Cui Yu Luo Jingjing Zhang Jie Xu Pei Hang He Le Peng Zhang | 2020 | National Science Review2020，7，2： | 5 |
| 5 | Targeting folate receptorβpositive tumor-associated macrophages in lung cancer with a folate-modified liposomal complex显示文摘Tumor-associated macrophages(TAMs)facilitate cancer progression by promoting tumor invasion,angiogenesis,metastasis,inflammatory responses,and immunosuppression.Folate receptorβ(FRβ)is overexpressed in TAMs.However,the clinical significance of FRβ-positive macrophages in lung cancer remains poorly understood.In this study,we verified that FRβoverexpression in lung cancer TAMs was associated with poor prognosis.We utilized a folate-modified lipoplex comprising a folatemodified liposome(F-PLP)delivering a BIM-S plasmid to target both lung cancer cells and FRβ-positive macrophages in the tumor microenvironment.Transfection of LL/2 cells and MH-S cells with F-PLP/pBIM induced cell apoptosis.Injection of F-PLP/pBIM into LL/2 and A549 lung cancer models significantly depleted FRβ-positive macrophages and reduced tumor growth.Treatment of tumor-bearing mice with F-PLP/pBIM significantly inhibited tumor growth in vivo by inducing tumor cell and macrophage apoptosis,reducing tumor proliferation,and inhibiting tumor angiogenesis.In addition,a preliminary safety evaluation demonstrated a good safety profile of F-PLP/pBIM as a gene therapy administered intravenously.This work describes a novel application of lipoplexes in lung cancer targeted therapy that influences the tumor microenvironment by targeting TAMs. | Yan Tie Heng Zheng Zhiyao He Jingyun Yang Bin Shao Li Liu Min Luo Xia Yuan Yu Liu Xiangxian Zhang Hongyi Li Min Wu Xiawei Wei | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 4 |
| 6 | Interaction of fatigue crack with vibration and ultrasound in metallic rod and its use for quantitative characterization显示文摘According to the principle of synchronous demodulation,the modulation information in the output signal of vibro-acoustic modulation test was investigated and the nonlinear interaction of sound and vibration with the crack interface in a metallic rod was analyzed.A swept signal excitation was used to obtain a proper high frequency parameter in the test of aluminum rod samples with different sizes of cracks and the modulation information in the output signal was analyzed.It was found that the ultrasound wave in the structure can be separated into two parts.One is the wave which passes through the crack interface modulated by the low frequency vibration,and other wave has no any changes.The nonlinear modulation model was modified and a quantitative method for crack detection was proposed.It is demonstrated by comparing with the ultrasonic C-scanning that this method can be used to estimate the fatigue crack size in the metallic rod. | LIU Bin GANG Tie WAN Chuhao LUO Zhiwei LUAN Yilin | 2016 | Chinese Journal of Acoustics2016，35，2： | 3 |
| 7 | Tracking SARS-CoV-2 Omicron diverse spike gene mutations identifies multiple inter-variant recombination events显示文摘The current pandemic of COVID-19 is fueled by more infectious emergent Omicron variants.Ongoing concerns of emergent variants include possible recombinants,as genome recombination is an important evolutionary mechanism for the emergence and re-emergence of human viral pathogens.In this study,we identified diverse recombination events between two Omicron major subvariants(BA.1 and BA.2)and other variants of concern(VOCs)and variants of interest(VOIs),suggesting that co-infection and subsequent genome recombination play important roles in the ongoing evolution of SARS-CoV-2.Through scanning high-quality completed Omicron spike gene sequences. | Junxian Ou Wendong Lan Xiaowei Wu Tie Zhao Biyan Duan Peipei Yang Yi Ren Lulu Quan Wei Zhao Donald Seto James Chodosh Zhen Luo Jianguo Wu Qiwei Zhang | 2022 | Signal Transduction and Targeted Therapy2022，7，5： | 3 |
| 8 | Experimental investigation on vibration characteristics of the medium-low-speed maglev vehicle-turnout coupled system显示文摘The steel turnout is one of the key components in the medium–low-speed maglev line system.However,the vehicle under active control is prone to vehicle–turnout coupled vibration,and thus,it is necessary to identify the vibration characteristics of this coupled system through field tests.To this end,dynamic performance tests were conducted on a vehicle–turnout coupled system in a medium–low-speed maglev test line.Firstly,the dynamic response data of the coupled system under various operating conditions were obtained.Then,the natural vibration characteristics of the turnout were analysed using the free attenuation method and the finite element method,indicating a good agreement between the simulation results and the measured results;the acceleration response characteristics of the coupled system were analysed in detail,and the ride quality of the vehicle was assessed by Sperling index.Finally,the frequency distribution characteristics of the coupled system were discussed.All these test results could provide references for model validation and optimized design of medium–low-speed maglev transport systems. | Miao Li Dinggang Gao Tie Li Shihui Luo Weihua Ma Xiaohao Chen | 2022 | Railway Engineering Science2022，30，2： | 3 |
| 9 | Minimally invasive transforaminal lumbar interbody fusion aided with computer-assisted spinal navigation system combined with electromyography monitoring显示文摘 | LUO Wei ZHANG Fan LIU Tie DU Xing-li CHEN An-ming LI Feng | 2012 | Chinese Medical Journal2012，，22： | 3 |
| 10 | 异基因造血干细胞移植术后侵袭性真菌感染的流行病学:单中心12年研究结果(英文)显示文摘目的:回顾性分析了浙江大学医学院附属第一医院骨髓移植中心1998年至2009年接受造血干细胞移植(HSCT)发生侵袭性真菌感染(IFI)的患者资料,评估HSCT后IFI发病情况、流行病学特征及危险因素,以期寻找病原菌特点及相关的危险因素,为制定更有针对性的预防治疗策略提供依据。创新点:首次对本中心异基因HSCT后的IFI感染情况进行统计分析,研究年限长,样本量较大;另作为国内较成熟的移植中心之一,本中心的研究结果对国内异基因HSCT后IFI感染情况有较大的参考意义。方法:对1998年11月至2009年12月在本移植中心接受异基因HSCT的408例患者进行观察分析,总结HSCT后IFI发病情况和病原菌分布,并采用多因素分析判断危险因素。结论:本研究显示IFI与HSCT预后明显相关,HSCT后不同时期IFI病原菌分布及危险因素存在差异。临床应根据IFI病原学特点及HSCT后时间分布特点,采取不同的策略,更有针对性地用药及开始治疗,从而改善预后。 | Ji-min SHI Xu-ying PEI Yi LUO Ya-min TAN Ru-xiu TIE Jing-song HE Wei-yan ZHENG Jie ZHANG Zhen CAI Mao-fang LIN He HUANG | 2015 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2015，16，9： | 2 |
| 11 | The Genomic Characterization of Enterovirus D68 from 2011 to 2015 in Beijing, China显示文摘enterovirus D68 上的回顾的监视研究在中国北京被执行,跟随最大、很普遍的 EV-D68 感染,它发生在 USA。从 2011 年 1 月到 2015 年 7 月, EV-D68 在中国北京与呼吸感染在 12 个个人被识别。种系发生的关系基于 genomic 顺序排列证明有二个系,从 2011 ~ 2015 在北京传播。属于的八 EV-D68 紧张组织 1 和四属于组 3。从在 2014 的北京的所有 EV-D68 紧张独立被聚类进组 1 的亚群 II。把结果基于这些,我们断定北京 EV-D68 紧张有小协会, EV-D68 紧张在 2014 美国爆发传播。 | ZHANG Tie Gang LI Hong Quan LI Ai Hua CHEN Meng GONG Cheng LUO Ming DONG Mei HUANG Fang | 2016 | Biomedical and Environmental Sciences2016，29，9： | 2 |
| 12 | Au/FeO_x-TiO_2 as an efficient catalyst for the selective hydrogenation of phthalic anhydride to phthalide显示文摘Au/FeO_x-TiO_2,prepared by deposition-precipitation method,is an efficient and stable catalyst for the liquid phase selective hydrogenation of phthalic anhydride to phthalide under mild reaction conditions. | Ying Xin Liu Tie Feng Xing Yi Ming Luo Xiao Nian Li Wei Yan | 2010 | Chinese Chemical Letters2010，21，11： | 2 |
| 13 | Assessing remotely sensed and reanalysis products in characterizing surface soil moisture in the Mongolian Plateau显示文摘Soil moisture(SM)plays a crucial role in the dynamics of coupled atmosphere,water,energy,and carbon cycles.In this study,the spatiotemporal distribution and variations of SM in the Mongolian Plateau were investigated for the period of 1982-2018 based on four gridded SM datasets.Taking the observed SM from 33 monitoring stations as a reference,the reliability of these four gridded products was validated,and the three-cornered hat(TCH)method was also applied to evaluate their uncertainties.Major results indicated that all these four products underestimated the SM in this region at different levels.The ERA-Interim SM performed much better than other three products,with a higher R of 0.53 and lower ubRMSE of 0.0378 m^(3)·m^(−3).Except for ECV,the surface SM exhibited a decreasing trend at−0.0004 to−0.0008 m^(3)·m^(−3)/decade in the warm season(from April to October)over the past 37 years.The greatest decreases in SM occurred in the summer season.Precipitation change plays a more important role in explaining the variations of SM than temperature reported by partial correlation analysis.The results of this study will benefit our understanding of the climate change effects and the protection of the ecological systems in this region. | Min Luo Chula Sa Fanhao Meng Yongchao Duan Tie Liu Yuhai Bao | 2021 | International Journal of Digital Earth2021，14，10： | 2 |
| 14 | Effect of Multi-Wall Carbon Nanotube on Fracture Mechanical Property of Cement-Based Composite显示文摘 | Luo Jian Lin Duan Zhong Dong Zhao Tie Jun Li Qiu Yi | 2011 | Advanced Materials Research2011，，146： | 1 |
| 15 | A Review of Molecular Makers Applied in Cowpea (Vigna unguiculata L. Walp.) Breeding显示文摘 | Huaqiang Tan Tan, Manman Tie Qian Luo Yongpeng Zhu Jia Lai Huanxiu Li | 2012 | Journal of Life Sciences2012，6，11： | 1 |
| 16 | Design and application of a new series of gallbladder endoscopes that facilitate gallstone removal without gallbladder excision 显示文摘 | TIE QIAO WAN-CHAO HUANG XIAO-BING LUO | 2012 | Review of Scientific Instruments2012，83，1： | 1 |
| 17 | Remote ischemic preconditioning for pediatric patients undergoing congenital cardiac surgery: A meta-analysis显示文摘 | Hong-Tao Tie Ming-Zhu Luo Zhen-Han Li Qian Wang Qing-Chen Wu | 2014 | International Journal of Cardiology2014，，： | 1 |
| 18 | Cooperative asynchronous multi-channel MAC: design, analysis, and implementation显示文摘 | Luo Tie Motani M and Srinivasan V | 2009 | IEEE Transactions on Mobile Computing2009，8，3： | 1 |
| 19 | Design and application of a new series of gallbladder endoscopes that facilitate gallstone removal without gallbladder excision显示文摘 | Tie Qiao Wan-Chao Huang Xiao-Bing Luo | 2012 | Review of Scientific Instruments2012，83，15： | 1 |
| 20 | Inhibition of human gastric carcinoma cell growth in vitro by a polysaccharide from Aster tataricus显示文摘 | Yunxin Zhang Qiusheng Wang Tie Wang Haikui Zhang Ying Tian Hong Luo Shen Yang Yuan Wang Xun Huang | 2012 | International Journal of Biological Macromolecules2012，，4： | 1 |
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