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| 1 | Programmable time-domain digital-coding metasurface for non-linear harmonic manipulation and new wireless communication systems显示文摘Optical non-linear phenomena are typically observed in natural materials interacting with light at high intensities, and they benefit a diverse range of applications from communication to sensing. However,controlling harmonic conversion with high efficiency and flexibility remains a major issue in modern optical and radio-frequency systems. Here, we introduce a dynamic time-domain digital-coding metasurface that enables efficient manipulation of spectral harmonic distribution. By dynamically modulating the local phase of the surface reflectivity, we achieve accurate control of different harmonics in a highly programmable and dynamic fashion, enabling unusual responses, such as velocity illusion. As a relevant application, we propose and realize a novel architecture for wireless communication systems based on the time-domain digital-coding metasurface, which largely simplifies the architecture of modern communication systems, at the same time yielding excellent performance for real-time signal transmission. The presented work, from new concept to new system, opens new pathways in the application of metamaterials to practical technology. | Jie Zhao Xi Yang Jun Yan Dai Qiang Cheng Xiang Li Ning Hua Qi Jun Chen Ke Guo Dong Bai Shuo Liu Shi Jin Andrea Alù Tie Jun Cui | 2019 | National Science Review2019，6，2： | 46 |
| 2 | Independent control of harmonic amplitudes and phases via a time-domain digital coding metasurface显示文摘Harmonic manipulations are important for applications such as wireless communications,radar detection and biological monitoring.A general approach to tailor the harmonics involves the use of additional amplifiers and phase shifters for the precise control of harmonic amplitudes and phases after the mixing process;however,this approach leads to issues of high cost and system integration.Metasurfaces composed of a periodic array of subwavelength resonators provide additional degrees of freedom to realize customized responses to incident light and highlight the possibility for nonlinear control by taking advantage of time-domain properties.Here,we designed and experimentally characterized a reflective time-domain digital coding metasurface,with independent control of the harmonic amplitude and phase.As the reflection coefficient is dynamically modulated in a predefined way,a large conversion rate is observed from the carrier signal to the harmonic components,with magnitudes and phases that can be accurately and separately engineered.In addition,by encoding the reflection phases of the meta-atoms,beam scanning for multiple harmonics can be implemented via different digital coding sequences,thus removing the need for intricate phase-shift networks.This work paves the way for efficient harmonic control for applications in communications,radar,and related areas. | Jun Yan Dai Jie Zhao Qiang Cheng Tie Jun Cui | 2018 | Light(Science & Applications)2018，7，1： | 29 |
| 3 | Wireless Communications with Programmable Metasurface:Transceiver Design and Experimental Results显示文摘Metasurfaces have drawn significant attentions due to their superior capability in tailoring electromagnetic waves with a wide frequency range, from microwave to visible light. Recently, programmable metasurfaces have demonstrated the ability of manipulating the amplitude or phase of electromagnetic waves in a programmable manner in real time, which renders them especially appealing in the applications of wireless communications. In this paper, we present the fundamental principle of applying programmable metasurface as transmitter for wireless communications. Then, we establish a prototype system of metasurface-based transmitter to conduct several experiments and measurements over the air, which practically demonstrate the feasibility of using programmable metasurfaces in future communication systems. By exploiting the dynamically controllable property of programmable metasurface, the design, implementation and experimental evaluation of the proposed metasurface-based wireless communication system are presented with the prototype, which realizes single carrier quadrature phase shift keying(QPSK) transmission over the air. In the developed prototype, the phase of the reflected electromagnetic wave of programma-ble metasurface is directly manipulated in real time according to the baseband control signal, which achieves 2.048 Mbps data transfer rate with video streaming transmission over the air. In addition, experimental result is provided to compare the performance of the proposed metasurface-based architecture against the conventional one. With the slight increase of the transmit power by 5 dB, the same bit error rate(BER) performance can be achieved as the conventional system in the absence of channel coding. Such a result is encouraging considering that the metasurface-based system has the advantages of low hardware cost and simple structure, thus leading to a promising new architecture for wireless communications. | Wankai Tang Xiang Li Jun Yan Dai Shi Jin Yong Zeng Qiang Cheng Tie Jun Cui | 2019 | China Communications2019，16，5： | 23 |
| 4 | Accurate and broadband manipulations of harmonic amplitudes and phases to reach 256 QAM millimeter-wave wireless communications by time-domain digital coding metasurface显示文摘We propose a theoretical mechanism and new coding strategy to realize extremely accurate manipulations of nonlinear electromagnetic harmonics in ultrawide frequency band based on a time-domain digital coding metasurface(TDCM).Using the proposed mechanism and coding strategy,we design and fabricate a millimeter-wave(mmWave) TDCM,which is composed of reprogrammable meta-atoms embedded with positive-intrinsic-negative diodes.By controlling the duty ratios and time delays of the digital coding sequences loaded on a TDCM,experimental results show that both amplitudes and phases of different harmonics can be engineered at will simultaneously and precisely in broad frequency band from 22 to33 GHz,even when the coding states are imperfect,which is in good agreement with theoretical calculations.Based on the fabricated high-performance TDCM,we further propose and experimentally realize a large-capacity mmWave wireless communication system,where 256 quadrature amplitude modulation,along with other schemes,is demonstrated.The new wireless communication system has a much simpler architecture than the currently used mmWave wireless systems,and hence can significantly reduce the hardware cost.We believe that the proposed method and system architecture can find vast application in future mmWave and terahertz-wave wireless communication and radar systems. | Ming Zheng Chen Wankai Tang Jun Yan Dai Jun Chen Ke Lei Zhang Cheng Zhang Jin Yang Lianlin Li Qiang Cheng Shi Jin Tie Jun Cui | 2022 | National Science Review2022，9，1： | 13 |
| 5 | An experimental study of fracture initiation mechanisms during hydraulic fracturing显示文摘破裂开始的机制是为水力的破裂技术的基本问题。因为在为不同水库的破裂开始机制的巨大的差别,成功的断裂技术用于孔水库的一些为折断的水库是徒劳的。用一台过程模拟设备的实验室测试被执行在不同水库证实破裂开始和繁殖的特征。破裂开始和繁殖上的外壳的压力地,限制压力,和自然破裂的影响被讨论。试验性的结果证明在洞附近的压力集中将显著地增加岩石的破裂压力。同时,在地上凿穿墙中的自然破裂将消除压力集中,它在破裂开始压力导致减少。 | Yan Tie Li Wei Bi Xueliang | 2011 | Petroleum Science2011，8，1： | 12 |
| 6 | Negative reflection and negative surface wave conversion from obliquely incident electromagnetic waves显示文摘Complete control of spatially propagating waves(PWs)and surface waves(SWs)is an ultimate goal that scientists and engineers seek for,in which negative reflection of PW and negative surface wave are two exotic phenomena.Here,we experimentally demonstrate an anisotropic digital coding metasurface capable of controlling both PWs and SWs with a single coding pattern.On the basis of the digital description of coding metasurfaces,a simple coding method is proposed to allow dual functionalities(either PW or SW manipulations)under two orthogonal polarizations at arbitrarily oblique incidences,thus improving the adaptability of digital coding metasurfaces in more practical circumstances.With elaborately designed ellipse-shaped coding particles,we experimentally demonstrate various functions under oblique incidences,including the negative reflection of PW,negative SW,anomalous reflection and their arbitrary combinations,all having good agreements with theoretical and numerical predictions.We believe that the proposed method may enable the digital coding metasurfaces to have broad applications in radar detections,wireless communications and imaging. | Shuo Liu Tie Jun Cui Ahsan Noor Zui Tao Hao Chi Zhang Guo Dong Bai Yan Yang Xiao Yang Zhou | 2018 | Light(Science & Applications)2018，7，1： | 10 |
| 7 | Rock fragmentation mechanisms and an experimental study of drilling tools during high-frequency harmonic vibration显示文摘Resonance drilling is a new technology,still at the laboratory stage.It has great potential to improve rock fragmentation efficiency.We analyzed the amplitude-frequency characteristics of steady-state mechanical vibration excited by harmonic vibration in rocks and an apparatus was built to achieve high frequency vibration of rock.The influence of rock drillability,rotary speed,excitation frequency,and other parameters on the rate of penetration(ROP) in resonance drilling was analyzed.The results show that the rock drillability decreased with an increase in excitation frequency.When drilling with a large size drill bit,the ROP increased with excitation frequency.The ROP reached a maximum value at the resonant frequency of the rock.The ROP of the bit increased linearly with rotary speed when no vibration was applied on the rock and increased approximately exponentially when harmonic vibration was applied.In addition,the resonant frequency of the rock was changing during the process of rock fragmentation,so in order to achieve the desired resonance of the rock,it is necessary to determine an appropriate harmonic vibration excitation frequency. | Li Wei Yan Tie Li Siqi Zhang Xiaoning | 2013 | Petroleum Science2013，10，2： | 9 |
| 8 | Allele-defined genome reveals biallelic differentiation during cassava evolution显示文摘Dear Editor,Generation of heterozygous genomes by hybridization between or within species can help maintain plant diversity and serve as a potential source of new species(Baek et al.,2018).Moreover,genomic heterozygosity is associated with genomic coadaptation,developmental stability,and heterosis.Accurate definition of alleles in haplotypes is necessary to precisely characterize allelic variation controlling agriculturally important traits(Shi et al.,2019).Currently,most released genomes have mosaic assembly of haplotypes due to random selection or collapse of alleles during genome assembly(Shi et al.,2019),which masked allelic variation and functional differentiation of divergent alleles in heterozygous species. | Wei Hu Changmian Ji Haitao shi Zhe Liang Zehong Ding Jianqiu Ye Wenjun Ou Gang Zhou Weiwei Tie Yan Yan Jinghao Yang Xiaoying Yang Yunxie Wei Zhiqiang Jin Jianghui Xie Ming Peng Wenquan Wang Anping Guo Biyu Xu Jianchun Guo Songbi Chen Liming Ma Mingcheng Wang Yang Zhou Xiaolong Li Ruoxi Li Siyi Guo Xinhui Xiao Zhongqing Wan Feifei An Jie Zhang Qingyun Leng Yin Li Ray Ming Kaimian Li | 2021 | Molecular Plant2021，14，6： | 8 |
| 9 | A new triterpenoid from Alisma orientalis显示文摘新 triterpenoid,命名 11,25-anhydro-alisol F,从 Alisma 东方人的根茎被孤立和九已知的混合物。他们的结构被分光镜的方法阐明。一些混合物在细胞毒素的实验显示出弱反肿瘤活动。 | Xue Yan Hu Yuan Qiang Guo Wen Yuan Gao Hai Xia Chen Tie Jun Zhang | 2008 | Chinese Chemical Letters2008，19，4： | 6 |
| 10 | Large-area high quality PtSe2 thin film with versatile polarity显示文摘Two-dimensional(2D)materials have attracted increasing attention for their outstanding structural and electrical properties.However,for mass-production of field effect transistors(FETs)and potential applications in integrated circuits,large-area and uniform 2D thin films with high mobility,large on-off ratio,and desired polarity are needed to synthesize firstly.Here,a transfer-free growth method for platinum diselenide(PtSe2)films has been developed.The PtSe2 films have been synthesized with various thicknesses in centimeter-sized scale.Typical FET made from a few layer PtSe2 show p-type unipolar,with a high field-effect hole mobility of 6.2 cm^(2) V^(−1) s^(−1) and an on-off ratio of 5×10^(3).The versatile semimetal-unipolar-ambipolar transition in synthesized PtSe2 films is also firstly observed as the thickness thinning.This work realizes the large-scale preparation of PtSe2 with prominent electrical properties and provides a new strategy for polarity's modulation. | Wei Jiang Xudong Wang Yan Chen Guangjian Wu Kun Ba Ningning Xuan Yangye Sun Peng Gong Jingxian Bao Hong Shen Tie Lin Xiangjian Meng Jianlu Wang Zhengzong Sun | 2019 | InfoMat2019，1，2： | 5 |
| 11 | Frequency-modulated continuous waves controlled by space-time-coding metasurface with nonlinearly periodic phases显示文摘The rapid development of space-time-coding metasurfaces(STCMs)offers a new avenue to manipulate spatial electromagnetic beams,waveforms,and frequency spectra simultaneously with high efficiency.To date,most studies are primarily focused on harmonic generations and independent controls of finite-order harmonics and their spatial waves,but the manipulations of continuously temporal waveforms that include much rich frequency spectral components are still limited in both theory and experiment based on STCM.Here,we propose a theoretical framework and method to generate frequency-modulated continuous waves(FMCWs)and control their spatial propagation behaviors simultaneously via a novel STCM with nonlinearly periodic phases.Since the carrier frequency of FMCW changes with time rapidly,we can produce customized time-varying reflection phases at will by the required FMCW under the illumination of a monochromatic wave.More importantly,the propagation directions of the time-varying beams can be controlled by encoding the metasurface with different initial phase gradients.A programmable STCM prototype with a full-phase range is designed and fabricated to realize reprogrammable FMCW functions,and experimental results show good agreement with the theoretical analyses. | Jun Chen Ke Jun Yan Dai Jun Wei Zhang Zhanye Chen Ming Zheng Chen Yunfeng Lu Lei Zhang Li Wang Qun Yan Zhou Long Li Jin Shan Ding Qiang Cheng Tie Jun Cui | 2022 | Light(Science & Applications)2022，11，10： | 4 |
| 12 | Targeting folate receptorβpositive tumor-associated macrophages in lung cancer with a folate-modified liposomal complex显示文摘Tumor-associated macrophages(TAMs)facilitate cancer progression by promoting tumor invasion,angiogenesis,metastasis,inflammatory responses,and immunosuppression.Folate receptorβ(FRβ)is overexpressed in TAMs.However,the clinical significance of FRβ-positive macrophages in lung cancer remains poorly understood.In this study,we verified that FRβoverexpression in lung cancer TAMs was associated with poor prognosis.We utilized a folate-modified lipoplex comprising a folatemodified liposome(F-PLP)delivering a BIM-S plasmid to target both lung cancer cells and FRβ-positive macrophages in the tumor microenvironment.Transfection of LL/2 cells and MH-S cells with F-PLP/pBIM induced cell apoptosis.Injection of F-PLP/pBIM into LL/2 and A549 lung cancer models significantly depleted FRβ-positive macrophages and reduced tumor growth.Treatment of tumor-bearing mice with F-PLP/pBIM significantly inhibited tumor growth in vivo by inducing tumor cell and macrophage apoptosis,reducing tumor proliferation,and inhibiting tumor angiogenesis.In addition,a preliminary safety evaluation demonstrated a good safety profile of F-PLP/pBIM as a gene therapy administered intravenously.This work describes a novel application of lipoplexes in lung cancer targeted therapy that influences the tumor microenvironment by targeting TAMs. | Yan Tie Heng Zheng Zhiyao He Jingyun Yang Bin Shao Li Liu Min Luo Xia Yuan Yu Liu Xiangxian Zhang Hongyi Li Min Wu Xiawei Wei | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 4 |
| 13 | Biosynthesis of Unsaturated Fatty Acids via Mortierella Isabellina Cultivated in a Medium Containing Butanol显示文摘Mortierella isabellina was found to accumulate large amounts of unsaturated fatty acids when it was grown in a medium containing butanol(5 g/L) and yeast extract(10 g/L) and cultivated at 25 ℃ for 5 d during which additional feeding butanol of 2 g/L was fed after being cultivated for 48 h . The resultant mycelial lipids accounted for 40 1% of the dry mycelia, while about 34% of butanol in the medium was converted. The mycelial lipids contained four kinds of unsaturated fatty acids, i.e ., palmitoleic(4 9%), oleic(54 1%), linoleic(10 4%) and linolenic(5 4%) acids. Those accounted for 74 8% of the total fatty acids. The effects of the culture conditions, such as cultivation temperature, initial pH of the medium and additional feeding butanol in the course of cultivation, on the production of mycelial lipids by M. isabellina were studied. | XIAN Mo 1, YAN Ji chang 2, CHENG Tie xin 1, KANG Yi jian 3, LI Wen xing 1, BI Ying li 1 and ZHEN Kai ji 1** 1. College of Chemistry, Jilin University, Changchun 130023, P. R. China 2. College of Chemistry, Northeast Normal University, C | 2002 | Chemical Research in Chinese Universities2002，18，3： | 3 |
| 14 | A versatile photodetector assisted by photovoltaic and bolometric effects显示文摘The advent of low-dimensional materials with peculiar structure and superb band properties provides a new canonical form for the development of photodetectors.However,the limited exploitation of basic properties makes it difficult for devices to stand out.Here,we demonstrate a hybrid heterostructure with ultrathin vanadium dioxide film and molybdenum ditelluride nanoflake.Vanadium dioxide is a classical semiconductor with a narrow bandgap,a high temperature coefficient of resistance,and phase transformation.Molybdenum ditelluride,a typical two-dimensional material,is often used to construct optoelectronic devices.The heterostructure can realize three different functional modes:(i)the p-n junction exhibits ultrasensitive detection(450 nm-2μm)with a dark current down to 0.2 pA and a response time of 17μs,(ii)the Schottky junction works stably under extreme conditions such as a high temperature of 400 K,and(iii)the bolometer shows ultrabroad spectrum detection exceeding 10μm.The flexible switching between the three modes makes the heterostructure a potential candidate for next-generation photodetectors from visible to longwave infrared radiation(LWIR).This type of photodetector combines versatile detection modes,shedding light on the hybrid application of novel and traditional materials,and is a prototype of advanced optoelectronic devices. | Wei Jiang Tan Zheng Binmin Wu Hanxue Jiao Xudong Wang Yan Chen Xiaoyu Zhang Meng Peng Hailu Wang Tie Lin Hong Shen Jun Ge Weida Hu Xiaofeng Xu Xiangjian Meng Junhao Chu Jianlu Wang | 2020 | Light(Science & Applications)2020，9，1： | 3 |
| 15 | Rapid Internal Control Reference Recombinase-Aided Amplification Assays for EBV and CMV Detection显示文摘Epstein-Barr virus(EBV)and cytomegalovirus(CMV),two of the most prevalent human herpesviruses,cause a wide spectrum of diseases and symptoms and are associated with serious health problem.In this study,we developed an internal control reference recombinase-aided amplification(ICR-RAA)assay for the rapid detection of EBV and CMV within 30 min.The assay had a sensitivity of 5 and 1 copies/test for EBV and CMV,respectively,with no cross reaction with other pathogens.In comparison with those of the commercial quantitative polymerase chain reaction(qPCR),the sensitivity of the EBV and CMV ICR-RAAs using extracted DNA was 93.33%and 84.84%,respectively;the specificity was 98.75%and 100.00%,respectively;and the Kappa values were 0.930 and 0.892(P<0.05),respectively.In comparison with those of qPCR,the sensitivity of the EBV and CMV ICR-RAAs using the DNA by thermal lysis was 72.22%and 80.00%,respectively;the specificity was 100.00%。 | GAO Yuan TIE Yan Qing ZHAO Lin Qing TAN He DING Nan DING Ya Xin GUO Qi ZHANG Rui Qing WANG Jin Rong CHEN Zi Wei FAN Guo Hao SHEN Xin Xin FENG Zhi Shan MA Xue Jun | 2021 | Biomedical and Environmental Sciences2021，34，8： | 3 |
| 16 | Identification of proteinaceous binding media for the polychrome terracotta army of Emperor Qin Shihuang by MALDI-TOF-MS显示文摘A proteinaceous binding media for the polychrome terracotta army of Emperor Qin Shihuang has been identified using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry(MALDI-TOF-MS).Methods for the preparation of the model samples and the elimination of interferences have been evaluated,as well as ageing processes.A method involving the complexation of EDTA in combination with dialysis was used to eliminate any interference in the polychrome layers taken from the historical samples.The model samples were aged by being buried in loess to replicate the ageing process of the historical samples as closely as possible.The optimum conditions for the extraction and subsequent enzymatic hydrolysis of the extracted protein were investigated.Under the optimized conditions,the‘‘peptide mass fingerprints’’of the proteinaceous binding media from the historical and model samples were determined by MALDITOF-MS.The results revealed that animal glue was used as the binding media for the polychrome layers of Emperor Qin Shihuang’s terracotta army.It also shows that animal glue used as binding media has a long history in China. | Hongtao Yan Jingjing An Tie Zhou Yin Xia Bo Rong | 2014 | Chinese Science Bulletin2014，59，21： | 3 |
| 17 | Analysis of proteinaceous binding media used in Tang Dynasty polychrome pottery by MALDI-TOF-MS显示文摘The proteinaceous binding media used in Tang Dynasty polychrome pottery was determined using matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF-MS). The optimum conditions for the extraction and subsequent enzymatic hydrolysis of the protein sample were established, and applied to the pretreatment of model and historical samples. Complexation of EDTA in combination with dialysis was determined to be the most effective method for eliminating interferences in polychrome layers taken from historical samples. Model samples were aged by burial in loess so as to more closely replicate the ageing process of the historical samples. Using the aforementioned optimized conditions, the 'peptide mass fingerprint' of the binding media of historical and model samples was determined by MALDI-TOF-MS. Comparisons between the 'peptide mass fingerprint' obtained for the historical sample and those of the model samples proved that animal glue was used as the binding media for the Tang Dynasty polychrome pottery. It also shows that animal glue used as binding media enjoys a long history in China. | YAN HongTao AN JingJing ZHOU Tie LI YuHu | 2013 | Chinese Science Bulletin2013，58，24： | 3 |
| 18 | Control of the harmonic near-field distributions by an active metasurface loaded with pin diodes显示文摘Recent advances of space-time-coding digital metasurfaces demonstrate powerful capabilities in the generation of nonlinear harmonics and the accurate control of the corresponding wavefronts. However, to date the near field manipulation and the experiment characterization are still not explored. In this paper, we propose a space-timedigital coding metasurface to realize accurate manipulation of the near fields at the fundamental and +1 st(-1 st)harmonics simultaneously, by properly controlling the initial phase and time delay of the time varying reflectivity.A novel mapping system is established to measure the nonlinear near field distributions of multiharmonics. Both the simulation and experimental results demonstrate the validity of the proposed method. | Jin Yang Jun Chen KE Mao CHEN Ming Zheng Chen Jun Yan Dai Jian Feng Chen Rui Yang Jun Wei Wu Qiang Cheng Tie Jun Cui | 2021 | Photonics Research2021，9，3： | 3 |
| 19 | Revised Super-long Down-regulation Protocol Improves the Outcome of Infertile Patients with Repeated Implantation Failure in IVF/ICSI-ET显示文摘Objective To investigate the outcome of revised super-long down-regulation protocol(RSDP) for in vitro fertilization / intracytoplasmic sperm injection-embryo transfer(IVF/ICSI-ET) in the special infertile patients with repeated implantation failure(RIF).Methods Patients with RIF were divided into RSDP group and routine long downregulation protocol(RLDP) group. In RSDP group, gonadotropin releasing hormone agonist(GnRHa) was injected intramuscularly by 2.5 mg in mid-luteal phase for the first time and 1.25 mg after 28 d; gonadotropin(Gn) was started 14 d later after the second GnRHa dose. IVF/ICSI-ET was performed according to the routine procedure. The clinical outcomes of RSDP group were compared with those of RLDP group.Results In RSDP group, the number of retrieved oocytes and valid embryos was significantly lower(P<0.05); there were no significant differences about fertilization rate(P>0.05); both good-quality embryo rate and implantation rate were significantly increased(P<0.005); clinical pregnancy rate was obviously improved(P<0.05), as compared with RLDP group.Conclusion RSDP can improve the IVF outcomes significantly in RIF patients. | Min-feng SHI Tie ZHOU Ying WANG Guang-hua CHEN Ming ZHU Jun OU Hui DU Tao-fei YAN Di SONG Ju-fen ZHENG Hui-qin ZHANG Ning HUI Ying-hao SUN | 2014 | Journal of Reproduction and Contraception2014，25，2： | 2 |
| 20 | Hepato-protective Effect of Polysaccharides Extracted from Inula Britannica Flower for Mice显示文摘The polysaccharides extracted from Inula britannica flower(IBP) exhibited a significant anti-liver injury activity.The properties and chemical compositions of IBP were analyzed via high performance liquid chromatography(HPLC) and infrared spectroscopy(IR) methods.The results show that the molecular weight distribution of IBP is from 600 to 3500.The weight-average molecular weight is 1099.IBP consists of mannose,glucuronic acid,rhamnose,galacturonic acid,glucose,galactose and arabinose with a molar ratio of 4.1:1:1.4:2.7:14.6:6.3:7.9.The IR spectrum of IBP reveals the typical characteristics of polysaccharides and proteins.After administration of IBP with 100,50 and 25 mg/kg body mass to liver injury mice induced by CCl 4 or bacillus calmette guerin-lipopolysaccharide(BCG-LPS),not only the blood alanine aminotransferase(ALT) and aspartate aminotransferase(AST) levels decreased significantly(P<0.05),but aslo the liver tissue malondialdehyde(MDA) level decreased significantly(P<0.01).The superoxide dismutase(SOD) level increased significantly(P<0.01).IBP shows significant anti-liver injury and antioxidation activity. | HONG Tie DONG Man GAO Yan ZHAO Jing WU Yi | 2012 | Chemical Research in Chinese Universities2012，28，6： | 2 |
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