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| 1 | Genome-wide Analysis of Plant-specific Dof Transcription Factor Family in Tomato显示文摘The Dof (DNA binding with One Finger) family encoding single zinc finger proteins has been known as a family of plant-specific transcription factors. These transcription factors are involved in a variety of functions of importance for different biological processes in plants. In the current study, we identified 34 Dof family genes in tomato (Solanum lycopersicum L.), distributed on 11 chromosomes. A complete overview of SlDof genes in tomato is presented, including the gene structures, chromosome locations, phylogeny, protein motifs and evolution pattern. Phylogenetic analysis of 34 SlDof proteins resulted in four classes constituting six clusters. In addition, a comparative analysis between these genes in tomato, Arabidopsis (Arabidopsis thaliana L.) and rice (Oryza sativa L.) was also performed. The tomato Dof family expansion has been dated to recent duplication events, and segmental duplication is predominant for the SlDof genes. Furthermore, the SlDof genes displayed differential expression either in their transcript abundance or in their expression patterns under normal growth conditions. This is the first step towards genome-wide analyses of the Dof genes in tomato. Our study provides a very useful reference for cloning and functional analysis of the members of this gene family in tomato and other species. | Xiaofeng Cai Yuyang Zhang Chanjuan Zhang Tingyan Zhang Tixu Hu Jie Ye Junhong Zhang Taotao Wang Hanxia Li Zhibiao Ye | 2013 | Journal of Integrative Plant Biology2013，55，6： | 26 |
| 2 | Bioaccumulation of Heavy Metal in Wild Growing Mushrooms from Liangshan Yi Nationality Autonomous Prefecture,China显示文摘The heavy metal bioaccumulation levels of 13 species of mushrooms were studied. 13 different species of wild mush-rooms growing in China were analyzed for Cu, Zn, Pb, Cd, and As. Contents of Cu, Zn, Cd and Pb in mushroom and Cu, Zn in soil were tested by atomic absorption spectrometer (AAS), and As in samples by atomic fluorescent light (AFL). Contents of Cd and Pb in soil were analyzed by graphite furnace AAS. The results showed that contents of Cu, Pb, Cd, and As in Termitomyces microcarpus were the highest in the tested mushroom samples, which were 135.00, 13.28, 65.30, and 1.60 mg·kg-1 (dry biomass) respectively, and the corresponding bioconcentration factor (BCF) for Cu and Cd was 57 and 1 674 separately, which was the highest data in 13 mushroom species. The capability of Boletus griseus for Cd accumulation was very strong with BCF of 300. when people consume the wild edible mushrooms, contents of Cd and Pb should be greatly considered. | ZHANG Dan GAO Tingyan MA Pei LUO Ying SU Pengcheng | 2008 | Wuhan University Journal of Natural Sciences2008，13，3： | 9 |
| 3 | Biosorption of Cu(Ⅱ) and Pb(Ⅱ) by Auricularia polytricha显示文摘For searching biological material for heavy metal removal of waste-water,using macrofungus Auricularia polytricha as biosorbent for Cu2+ and Pb2+ removal was investigated. After shaking and biosorbing Cu2+ and Pb2+ in solution by biosorbents,the filtrates were tested by AAS and the adsorbed quantity of Cu2+ and Pb2+ was calculated . The biosorbents were effective in removal of Cu2+ and Pb2+ on the biosorbents that showed a high-est value around pH 5-6. The biosorption rate of Cu2+ and Pb2+ on A. polytri-cha biomass decreased with increasing the initial concentration of Cu2+ and Pb2+ in the medium. The biosorption of Cu2+ and Pb2+ on the biomasses fol-lows pseudo-second order kinetics. The determined maximum biosorption capacities presented by the fungus biomass were 3.34 and 13.03 mg·g-1 dry weight for Cu2+ and Pb2+,respectively by the biosorption equilibrium with Langmuir adsorption isotherm. According to the whole data analysis in each experiment of studying Cu2+ and Pb2+ biosorption including condition factors and adsorption isotherm,the adsorbed capacity of Pb2+ by A. polytricha bio-mass was bigger than Cu2+. The biosorption by A. polytricha was most effec-tive when pH 5-6. The biosorbents are suitable for low Cu2+ and Pb2+ con-centration waste-water,especially for Pb2+ removal. | ZHANG Dan GAO Jianwei GAO Tingyan YING Yigao CHEN Hong | 2007 | Wuhan University Journal of Natural Sciences2007，12，4： | 4 |
| 4 | Stage Division and Pattern Discovery of Complex Patient Care Processes显示文摘This paper studies the design of a clinical pathway that defines medical service activities within each stage of a patient care process. Much prior research has developed clinical process models that consider the trajectory of services occurring in a care process, by using data mining techniques on process execution logs. A novel approach that provides a more efficient way of clinical pathway design is introduced in this paper. Based on the strategy of TEI@I methodology, the proposed approach integrates statistical methods, optimization techniques and data mining. With the preprocessed data,a complex care process is subsequently divided into several medical stages, and then the patterns of each stage are identified, and thus a clinical pathway is developed. Finally, the proposed method is applied to the real world, using archival data derived from a hospital in Beijing, about three diseases that involve various departments, with an average of 300 samples for each disease. The results of realworld applications demonstrate that the proposed method can automatically and efficiently facilitate clinical pathways design. The main contributions to the field in this paper include(a) a new application of TEI@I methodology in healthcare domain,(b) a novel method for complex processes analysis,(c)tangible evidence of automatic clinical pathways design in the real world. | WANG Tingyan TIAN Xin YU Ming QI Xin YANG Lan | 2017 | Journal of Systems Science & Complexity2017，30，5： | 4 |
| 5 | Generation of sp3111 transgenic RNAi mice via permanent integration of small hairpin RNAs in repopulating spermatogonial cells in vivo显示文摘spermatid 特定的基因, sp3111,是 four-transmembrane 基因家庭的一个新成员。然而,它的繁殖生物功能留下逃犯。这研究的目的是为进一步在它的繁殖功能上学习 sp3111 基因表示的抑制的效果建立一个 sp3111 击倒的雄的老鼠模型。pSUPER-sp3111-shRNA 的 Recombinant 向量,对老鼠 sp3111 mRNA 的不同区域包含抄录功能的小发卡 RNA 顺序,被构造并且识别。然后,线性化的 recombinant 向量被 electroporation 注入成熟老鼠睾丸和 transfected 到 spermatogonial 房间产生 sp3111 转基因的 RNAi 老鼠。这些 electroporated 男性老鼠与野类型的女性一起被交配在 electroporation 和他们的子孙以后的 30 天被荧光显微镜学和 PCR 两个都检验。在 vivo 的 sp3111 mRNA 的睾丸表达式上的 RNAi 的抑制效率是超过30%并且能稳定地被传给 F3 产生,这被发现,并且与野类型的雄的鼠标相比,吗 sp3111 RNAi 雄的鼠标的后代的吝啬的数字从 11 被减少???????????????????????栠吗?? | Weili Shi Tingyan Shi Zheyu Chen Jufang Lin Xiaofeng Jia Jian Wang Huijuan Shi | 2010 | Acta Biochimica et Biophysica Sinica2010，42，2： | 2 |
| 6 | The Effect of Online Channel Addition on Store Performance:Empirical Evidence from Chinese Chain Retailers显示文摘With the rapid development of e-Commerce and takeaway platforms, retailers have gradually developed multi-channel operations. However, limited empirical studies explored the effects of an online channel offered by takeaway platforms on the store performance. Does an online channel addition have a synergy effect or a cannibalization effect on store performance? We empirically investigate these effects by analyzing a large dataset including diverse samples collected from multiple retailers across various regions. The dataset includes 2115 stores across 25 retailers for 10 months that includes two types of retail formats and covers 16 provinces and 21 cities of China. We study the impacts of the newly introduced online channel on the incumbent offline channel and the overall store performance.The empirical results reveal that the online channel addition mainly has a synergy effect. Specifically,for the overall store, it has a positive effect on the sales and product variety, whereas it has a negative effect on the basket size. Surprisingly, an online channel addition also has a positive effect on the offline sales. Our study adds novel values to multi-channel retailing literature by empirically researching the cannibalization and synergy effect of a new type of online channel, offered by takeaway platforms. It can provide insights for retail enterprises who are interested in introducing O2 O model. | Yixin WANG Qiguo GONG Tingyan WANG Xin TIAN | 2021 | Journal of Systems Science and Information2021，9，4： | 2 |
| 7 | Carbon-nanoparticle-assisted growth of high quality bilayer WS2 by atmospheric pressure chemical vapor deposition显示文摘Two-dimensional(2D)WS2 offers great prospects for assembling next-generation optoelectronic and electronic devices due to its thickness-dependent optical and electronic properties.However,layer-number-controlled growth of WS2 is still a challenge up to now.This work presents controlled growth of bilayer WS2 triangular flakes by carbon-nanoparticle-assisted chemical vapor deposition(CVD)process.The growth mechanism is also proposed.In addition,the field effect transistors(FETs)based on monolayer and bilayer WS2 are also fabricated and investigated.The bilayer FET displays a mobility of 34 cm2·V^-1·s^-1,much higher than that of the monolayer FET.The high figures of merit make bilayer WS2 a promising candidate in high-performance electronics and optoelectronics. | Jieyuan Liang Lijie Zhang Xiaoxiao Li Baojun Pan Tingyan Luo Dayan Liu Chao Zou Nannan Liu Yue Hu Keqin Yang Shaoming Huang | 2019 | Nano Research2019，12，11： | 2 |
| 8 | Improvement of- methane drainage in high gassy coal seam using waterjet technique 显示文摘 | Tingkan Lu Hong Yu Tingyan Zhou | 2009 | International Journal of Coal Geology2009，79，12： | 1 |
| 9 | Landscape dynamic network biomarker analysis reveals the tipping point of transcriptome reprogramming to prevent skin photodamage显示文摘Skin,as the outmost layer of human body,is frequently exposed to environmental stressors including pollutants and ultraviolet(UV),which could lead to skin disorders.Generally,skin response process to ultraviolet B(UVB)irradiation is a nonlinear dynamic process,with unknown underlying molecular mechanism of critical transition.Here,the landscape dynamic network biomarker(lDNB)analysis of time series transcriptome data on 3D skin model was conducted to reveal the complicated process of skin response to UV irradiation at both molecular and network levels.The advanced l-DNB analysis approach showed that:(i)there was a tipping point before critical transition state during pigmentation process,validated by 3D skin model;(ii)13 core DNB genes were identified to detect the tipping point as a network biomarker,supported by computational assessment;(iii)core DNB genes such as COL7A1 and CTNNB1 can effectively predict skin lightening,validated by independent human skin data.Overall,this study provides new insights for skin response to repetitive UVB irradiation,including dynamic pathway pattern,biphasic response,and DNBs for skin lightening change,and enables us to further understand the skin resilience process after external stress. | Chengming Zhang Hong Zhang Jing Ge Tingyan Mi Xiao Cui Fengjuan Tu Xuelan Gu Tao Zeng Luonan Chen | 2021 | Journal of Molecular Cell Biology2021，13，11： | 1 |
| 10 | Preparation and properties of AION transparent ceramics 显示文摘 | TIAN Tingyan DU Hongbing JIANG Huawei | 2010 | J Chin Ceram Soc2010，38，8： | 1 |
| 11 | Improved magneto- striction of Dy-doped FeB3 Ga17 melt-spun ribbons显示文摘 | Jin Tingyan Wu Wei Jiang Chengbao | 2014 | Scripta Mater2014，74，： | 1 |
| 12 | 白细胞介素-18抑制Lewis肺癌小鼠移植瘤生长与诱导移植瘤细胞凋亡的研究(英文)显示文摘Objective:The aim of our study was to investigate the effects of interleukin-18(IL-18) on implanted Lewis lung cancer in suppressing tumor growth and inducing tumor cells apoptosis.Methods:One week after hypodermic inoculation of Lewis cells, sixteen tumor-bearing syngeneic mice were randomly divided into two groups.The mice in the treatment group were intraperitoneal injected with the IL-18, in the control group were intraperitoneal injected with normal saline.The health conditions of the mice were measured, the morphology of the tumors was studied and the apoptosis of implanted lung cancer cells was detected by TUNEL to evaluated the effects of IL-18.Results:IL-18 had no significant effects on the health conditions of the mice, but it could suppress the implanted tumor growth(inhibition rate was 75%) and induce tumor cells apoptosis.Conclusion:IL-18 can suppress the implanted Lewis lung cancer cells by way of inducing tumor cells apoptosis.It could be used as a new strategy for lung cancer. | Sheng Yang Huishan Lu Xiangqi Chen Tingyan Lin Zhiying Li Mingqiang Kang | 2010 | The Chinese-German Journal of Clinical Oncology2010，9，3： | 1 |
| 13 | Fast realization algorithms for determinig regularization parameters in linear inverse problems显示文摘 | Wang Yanfei Xiao Tingyan | 2001 | Inverse Problems2001，17，： | 1 |
| 14 | Plasmacytoid dendritic cells promote acute kidney injury by producing interferon-α显示文摘Acute kidney injury(AKI)is a common clinical complication associated with high mortality in patients.Immune cells and cytokines have recently been described to play essential roles in AKI pathogenesis.Plasmacytoid dendritic cells(pDCs)are a unique DC subset that specializes in type Ⅰ interferon(IFN)production.Here,we showed that pDCs rapidly infiltrated the kidney in response to AKI and contributed to kidney damage by producing IFN-α.Deletion of pDCs using DTR^(BDCA2) transgenic(Tg)mice suppressed cisplatin-induced AKI,accompanied by marked reductions in proinflammatory cytokine production,immune cell infiltration and apoptosis in the kidney.In contrast,adoptive transfer of pDCs during AKI exacerbated kidney damage.We further identified IFN-α as the key factor that mediated the functions of pDCs during AKI,as IFN-α neutralization significantly attenuated kidney injury.Furthermore,IFN-α produced by pDCs directly induced the apoptosis of renal tubular epithelial cells(TECs)in vitro.In addition,our data demonstrated that apoptotic TECs induced the activation of pDCs,which was inhibited in the presence of an apoptosis inhibitor.Furthermore,similar deleterious effects of pDCs were observed in an ischemia reperfusion(IR)-induced AKI model.Clinically,increased expression of IFN-α in kidney biopsies was observed in kidney transplants with AKI.Taken together,the results of our study reveal that pDCs play a detrimental role in AKI via IFN-α. | Bo Deng Yuli Lin Yusheng Chen Shuai Ma Qian Cai Wenji Wang Bingji Li Tingyan Liu Peihui Zhou Rui He Feng Ding | 2021 | Cellular & Molecular Immunology2021，18，1： | 1 |
| 15 | Probabilistic framework for assessing the accuracy of data mining tool for online prediction of transient stability显示文摘 | Guo Tingyan Milanovi?J V | 2014 | IEEE Transactions on Power Systems2014，29，1： | 1 |
| 16 | Synthesis, crystal structure and esterification of a novel iron( III ) 18-metallacrown-6 complex显示文摘 | Jiang Tingyan Zhong Hongjuan Xiang Ting | 2009 | Inorg Chim Acta2009，362，13： | 1 |
| 17 | Preparation and characterization of a strong basic anion exchanger by radiation-induced grafting of styrene onto poly(tetrafluoroethylene) fiber显示文摘 | Qikun Zhang Sujuan Zhang Shuixia Chen Peiyuan Li Tingyan Qin Siguo Yuan | 2008 | Journal of Colloid And Interface Science2008，，2： | 1 |
| 18 | Water resistance of composite binders containing phosphogpysum with different pretreatment processes显示文摘 | Tingyan Ren Jing Zhu Wanchao Liu | | 0，，01： | 1 |
| 19 | Combined antitumor activity of cucurbitacin B and docetaxel in laryngeal cancer显示文摘 | Tingyan Liu Meixia Zhang Hongliang Zhang Chunyan Sun Xiaolin Yang Yihui Deng Wenyue Ji | 2008 | European Journal of Pharmacology2008，，1： | 1 |
| 20 | Homocysteine impaired endothelial function through compromised vascular endothelial growth factor/Akt/endothelial nitric oxide synthase signalling显示文摘 | Ting‐TingYan QianLi Xuan‐HongZhang Wei‐KangWu JuanSun LinLi QuanZhang Hong‐MeiTan | 2010 | Clinical and Experimental Pharmacology and Physiology2010，，11： | 1 |
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