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| 1 | Association of fluid-attenuated inversion recovery vascular hyperintensity with ischaemic events in internal carotid artery or middle cerebral artery occlusion显示文摘Background and purpose Individuals with intracranial artery occlusion have high rates of ischaemic events and recurrence.It has been challenging to identify patients who had high-risk stroke using a simple,valid and non-invasive screening approach.This study aimed to investigate whether fluid-attenuated inversion recovery(FLAIR)vascular hyperintensity(FVH),a specific imaging sign on the FLAIR sequence,could be a predictor of ischaemic events in a population with internal carotid artery(ICA)or middle cerebral artery(MCA)occlusion.Methods We retrospectively analysed 147 patients(mean 60.43±12.83 years)with 149 lesions,including 37 asymptomatic and 112 symptomatic cases of ICA or MCA occlusion.Symptomatic occlusion was considered if ischaemic events were present in the relevant territory within 90 days.FVH Alberta Stroke Program Early Computed Tomography Score(FVH-ASPECTS:0-7,with 0 indicating absence of FVH and 7 suggesting prominent FVH)and collateral circulation grade were assessed for each participant.Multivariable logistic regression analysis was performed to detect independent markers associated with symptomatic status.Results A lower FVH-ASPECTS was associated with a more favourable collateral circulation grade(rho=−0.464,p<0.0001).The FVH-ASPECTS was significantly lower in the asymptomatic occlusion group than in the symptomatic occlusion group(p<0.0001).FVH-ASPECTS(Odd ratio,2.973;95%confidence interval,1.849 to 4.781;p<0.0001)was independently associated with symptomatic status after adjustment for age,sex,lesion location and collateral circulation grade in the multivariate logistic regression.The area under the curve was 0.861 for the use of FVH-ASPECTS to identify symptomatic occlusion.Conclusions The ability to discriminate symptomatic from asymptomatic occlusion suggests that FVH may be a predictor of stroke.As a simple imaging sign,FVH may serve as a surrogate for haemodynamic impairments and can be used to identify high-risk stroke cases early in ICA or MCA occlusion. | Jinhao Lyu Jianxing Hu Xinrui Wang Xiangbing Bian Mengting Wei Liuxian Wang Qi Duan Yina Lan Dekang Zhang Xueyang Wang Tingyang Zhang Chenglin Tian Xin Lou | 2023 | Stroke & Vascular Neurology2023，8，1： | 1 |
| 2 | Knowledge,Attitude and Practice(K-A-P)of Cancer Nutrition in Chinese Medical Staff显示文摘Objective The present study was designed to investigate knowledge,attitude,and practice(K-A-P)toward cancer nutrition among medical staff in China,and to provide a basis for nutritional oncology training in clinical oncology practice in China in order to improve clinical treatment outcomes.Method This was a multicenter,cross-sectional study involving 3036 clinicians selected from 138 hospitals in 13 provinces across China.KAP scores were collected via questionnaires.Results The overall mean K score was 41.26±23.68,with a pass rate of 35.31%and honoring rate of 12.48%,respectively.The overall mean A score was 82.23±12.63,with pass rate of 96.57%and honoring rate of 69.37%,respectively.The overall mean P score was 73.03±15.06,with a pass rate of 85.64%and honoring rate of 39.86%,respectively.The correlation coefficient between K and A scores was 0.136(P<0.05).The correlation coefficient between K and P scores was 0.179(P<0.05).These results suggested positive correlations between K and A,and K and P scores.While the pass rate for K score in male staff was higher than that in female(P<0.05),there was no significant difference for A and P scores between the two groups(P >0.05).The K-A-P scores,and their associated pass rates and honoring rates among doctors were higher than that among nurses and medical technicians(P<0.05).Senior medical technicians had higher K and P scores than their junior counterparts(P<0.05).However,there was no significant difference in A scores among medical technicians with different ranks(P >0.05).Mean K-A-P scores and their associated pass rates and honoring rates in clinicians with higher degrees were superior,compared with those with lower degrees(P<0.05).Surgeons had higher K-A-P scores,pass rates,and honoring rates than others(P<0.05).Those who worked in teaching hospitals showed higher K-A-P scores,pass rates,and honoring rates than their counterparts in other work settings.There were no significant differences in K and P scores,and associated pass rates and good rates between medical staff from general hospitals and those from specialized oncology hospitals(P >0.05).However,higher P scores and associated pass rates were observed in staff from general hospitals than that from other settings(P<0.05).Over half(58.41%)of the medical staff spent less than 10%of their work time on nutritional education.About half(52.71%)of the medical staff expressed desires to work on nutritional research projects.Nutritional knowledge of medical staff primarily came from work experience(66.22%),reference textbooks and journals(65.40%),and formal education(61.25%).Conclusion While medical staff in China demonstrated positive attitude and good practice in nutritional therapy,they need more training to improve nutritional knowledge. | Xiao Wei Zhang Wei Li Gong Yan Chen Guang Fa Zhao Jian Si Chen Su Xia Luo TingYang Jin Huang Yan Jin Chen Su Yun Li Lan Zhou Wen Hu Chang Hai Zhao Shao Zhong Wei Han Ping Shi Chinese Society for Oncological Nutrition and Supportive Care(CSONSC) | 2017 | Journal of Nutritional Oncology2017，2，2： | 0 |
| 3 | Studies of Selective Arterial Perfusion plus Chemoembolization on Hepatic Metastasis from Rectal Cancer显示文摘OBJECTIVE To develop an effectual method for treating hepatic metas-tasis from rectal cancer. METHODS A randomized control study of celiac artery perfusion plus transcatheter hepatic arterial chemoembolization (TACE) (observation group) and intravenous chemotherapy (control group) for 99 cases with hepatic me-tastasis from rectal cancer was performed. The perfusion was repeated once at 4 weeks after the first treatment of 52 cases in the observation group, and it was subsequently repeated at an interval of 2 or 3 months. Using intrave-nous administration, the perfusion was repeated once every 3 weeks with 47 cases in the control group. RESULTS Three months after treatment, the patients in the observation group who showed a relief or elimination of a former superior abdominal pain amounted to 70.6%, and those with a diminution of their intrahepatic mass reached 55.8%. In the control group, the patients with a relief or disappear-ance of hepatalgia reached 20%, and those with a diminution of their intrahe-patic mass reached 10.6%. The 1, 2 and 3-year survival rates were 80.8%, 46.2% and 25.0% in the cases of the observation group and 61.7%, 19.1% and 4.3% in the control group, respectively. CONCLUSION For the patients who failed to receive a surgical opera-tion on their hepatic metastasis from rectal cancer, celiac artery perfusion plus TACE is a more effective regimen for improvement of the clinical symp-toms and extension of the survival time, compared to intravenous chemo-therapy, and is a better choice for palliative therapy. | Shiliang Tu Jianhua Yuan Gaoli Deng Tingyang Hu Quanjin Dong | 2007 | Chinese Journal of Clinical Oncology2007，4，3： | 0 |
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