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| 1 | Gamma knife stereotactic radiosurgery for the management of incidentally-identified brain metastasis from non-small cell lung cancer显示文摘 | Marko NF Suh JH Chao ST Barnett GH Vogelbaum MA Toms S Well R J Angelov L | 2011 | 中国神经肿瘤杂志2011，9，1： | 4 |
| 2 | Subcellular spatial resolution achieved for deep-brain imaging in vivo using a minimally invasive multimode fiber显示文摘Achieving intravital optical imaging with diffraction-limited spatial resolution of deep-brain structures represents an important step toward the goal of understanding the mammalian central nervous system1–4.Advances in wavefrontshaping methods and computational power have recently allowed for a novel approach to high-resolution imaging,utilizing deterministic light propagation through optically complex media and,of particular importance for this work,multimode optical fibers(MMFs)5–7.We report a compact and highly optimized approach for minimally invasive in vivo brain imaging applications.The volume of tissue lesion was reduced by more than 100-fold,while preserving diffraction-limited imaging performance utilizing wavefront control of light propagation through a single 50-μm-core MMF.Here,we demonstrated high-resolution fluorescence imaging of subcellular neuronal structures,dendrites and synaptic specializations,in deep-brain regions of living mice,as well as monitored stimulus-driven functional Ca2+responses.These results represent a major breakthrough in the compromise between high-resolution imaging and tissue damage,heralding new possibilities for deep-brain imaging in vivo. | Sebastian A.Vasquez-Lopez Raphaël Turcotte Vadim Koren Martin Plöschner Zahid Padamsey Martin J.Booth TomášČižmár Nigel J.Emptage | 2018 | Light(Science & Applications)2018，7，1： | 4 |
| 3 | 系统性药物治疗儿童银屑病的安全性显示文摘银屑病是一种常见的慢性炎症性皮肤病。成年人的发病率为2%~3%,其中大约有三分之一的患者在18岁之前发病。在儿童期,该病的发病率呈线性增长。从1970年至2000年,儿童银屑病的发病率增加了一倍多。尽管对许多轻度银屑病患儿而言,局部治疗已足够,但对更多可能影响生活质量的重度或顽固性的银屑病患儿,则往往需要系统性治疗。 | bronckers imgj seyger mmb west dp lara-corrales i tollefson m tom wl hogeling m belazarian l zachariae c mahé e siegfried e philipp s szalai z vleugels ra holland k murphy r baselga e cordoro k lambert j alexopoulos a mrowietz u kievit w paller as 邓婕(编译) 张锡宝(审校) 无 | 2017 | 皮肤性病诊疗学杂志2017，24，5： | 3 |
| 4 | Age at diagnosis of type 2 diabetes and cardiovascular risk factor profile:A pooled analysis显示文摘BACKGROUND The diagnosis of type 2 diabetes(T2D)in younger adults,an increasingly common public health issue,is associated with a higher risk of cardiovascular complications and mortality,which may be due to a more adverse cardiovascular risk profile in individuals diagnosed at a younger age.AIM To investigate the association between age at diagnosis and the cardiovascular risk profile in adults with T2D.METHODS A pooled dataset was used,comprised of data from five previous studies of adults with T2D,including 1409 participants of whom 196 were diagnosed with T2D under the age of 40 years.Anthropometric and blood biomarker measurements included body weight,body mass index(BMI),waist circumference,body fat percentage,glycaemic control(HbA1c),lipid profile and blood pressure.Univariable and multivariable linear regression models,adjusted for diabetes duration,sex,ethnicity and smoking status,were used to investigate the association between age at diagnosis and each cardiovascular risk factor.RESULTS A higher proportion of participants diagnosed with T2D under the age of 40 were female,current smokers and treated with glucose-lowering medications,compared to participants diagnosed later in life.Participants diagnosed with T2D under the age of 40 also had higher body weight,BMI,waist circumference and body fat percentage,in addition to a more adverse lipid profile,compared to participants diagnosed at an older age.Modelling results showed that each one year reduction in age at diagnosis was significantly associated with 0.67 kg higher body weight[95%confidence interval(CI):0.52-0.82 kg],0.18 kg/m^(2) higher BMI(95%CI:0.10-0.25)and 0.32 cm higher waist circumference(95%CI:0.14-0.49),after adjustment for duration of diabetes and other confounders.Younger age at diagnosis was also significantly associated with higher HbA1c,total cholesterol,low-density lipoprotein cholesterol and triglycerides.CONCLUSION The diagnosis of T2D earlier in life is associated with a worse cardiovascular risk factor profile,compared to those diagnosed later in life. | Mary M Barker Francesco Zaccardi Emer M Brady Gaurav S Gulsin Andrew P Hall Joseph Henson Zin ZinHtike Kamlesh Khunti Gerald P McCann Emma L Redman David R Webb Emma G Wilmot Tom Yates Jian Yeo Melanie J Davies Jack A Sargeant | 2022 | World Journal of Diabetes2022，13，3： | 2 |
| 5 | Where is the global in global mental health?A call for inclusive multicultural collaboration显示文摘To the editor:Common mental health disorders,like depression and anxiety,account for 45%of the global disease burden on youths aged 15-29.1 This challenge is particularly significant in low and middle-income countries(LMICs)where risk factors such as poverty,limited treatment options and stigma restrict access to care and exacerbate the burden and magnify the impact of mental disorders.23 Given these barriers,there is an urgent need for research dedicated to expanding mental healthcare for young people in LMICs. | Tom L Osborn Akash R Wasil John R Weisz Arthur Kleinman David M Ndetei | 2020 | General Psychiatry2020，33，6： | 2 |
| 6 | Causes of encephalitis and differences in their clinical presentations in England: a multicentre, population-based prospective study显示文摘 | Julia Granerod Helen E Ambrose Nicholas WS Davies Jonathan P Clewley Amanda L Walsh Dilys Morgan Richard Cunningham Mark Zuckerman Ken J Mutton Tom Solomon Katherine N Ward Michael PT Lunn Sarosh R Irani Angela Vincent David WG Brown Natasha S Crowcroft | 2010 | The Lancet Infectious Diseases2010，，12： | 2 |
| 7 | Polybrominated diphenyl ethers (PBDEs) in sediment by salinity and land-use type from Australia显示文摘 | TOMS L M L MORTIMER M SYMONS R K | 2008 | Environment International2008，34，： | 1 |
| 8 | Tectonostratigraphic development of the Interior Sudan Rifts,Central Africa显示文摘 | TIM R Mchargue TOM L Heidrick JACK E Livingston | 1992 | Tectonophysics1992，21，3： | 1 |
| 9 | Assessment of polybrominated diphenyl ethers (PBDEs) in samples collected from indoor environments in South East Queensland, Australia 显示文摘 | TOMS L M L BARTKOW M E SYMONS R | 2009 | Chemosphere2009，76，： | 1 |
| 10 | Anti-tumor immunity: Myeloid leukocytes control the immune langscape显示文摘 | Melanie R Rutkowski MR Tom L | 2012 | Cell Immu- nol2012，278，12： | 1 |
| 11 | A receptor kinase-like protein encoded by the rice disease resistance gene, Xa21显示文摘 | Song W Y Wang G L Chen L L HanSuk K Pi L Y Tom H GardnerJ Wang B Zhai W X Zhu L H Claude F Pamela R | 1995 | Science1995，270，5243： | 1 |
| 12 | Human microvascular endothelial cell-extracellular matrix interaction in cellular growth state determination显示文摘 | Mallery S R Lantry L E Toms M C | 1995 | Cell Tissue Res1995，279，1： | 1 |
| 13 | Freely dispersible Au@TiO2, Au@ZrO2, Ag@TiO2, and Ag@ZrO2 core-shell nanoparticles: One-step synthesis, characterization, spectroscopy, and optical limiting properties 显示文摘 | TOM R T NAIR A S SINGH N ASLAM M NAGENDRA C L PHILIP R VIJAYAMOHANAN K PRADEEP T | 2003 | Langmuir2003，19，： | 1 |
| 14 | Rehabilitation of executive functioning after focal damage to the cerebellum显示文摘 | Tom A S Brian L Dmytro R | 2008 | Neurorehabil Neural Repair2008，22，： | 1 |
| 15 | Experimental methods for laboratory-scale ensilage of lignocellulosic biomass 显示文摘 | Deepti T Tom L R Megan N M | 2012 | Bio- mass and Bioenergy2012，47，： | 1 |
| 16 | Transfection of HEK293-EBNA1 Cells in Suspension with Linear PEI for Production of Recombinant Proteins显示文摘 | Tom R Bisson L Durocher Y | 2008 | Cold Spring Harbor Protocols2008，3，3： | 1 |
| 17 | Succession of Hydrocarbon-Degrading Bacteria in the Aftermath of the Deepwater Horizon Oil Spill in the Gulf of Mexico 显示文摘 | Dubinsky E A Conrad M E Chakraborty R Bill M Borg Hollibaugh J T Mason O U M Piceno Y Reid F C Stringfcllow W T Tom L M Hazen T C Andersen G L | 2013 | Environ Sei Technol2013，47，10： | 1 |
| 18 | Tectonostratigraphic development of the Interior Sudan Rifts,Central Africa 显示文摘 | TIM R Mchargue TOM L Heidrick JACK E Livingston | 1992 | Tectonophysics1992，21，3： | 1 |
| 19 | Effects of salt on the intrinsic viscosity of model alkali-soluble associative polymers显示文摘 | Guo L Tom K C Jankins R D | 1998 | Macromol Chem Phys1998，199，6： | 1 |
| 20 | Semon manipulations:improved sperm recovery function with a two-layer percoll gradient显示文摘 | McClure RD Nues L Tom R | 1985 | Fertil Steril1985，43，： | 1 |
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