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| 1 | Effects of early enteral nutrition on immune function of severe acute pancreatitis patients显示文摘AIM:To investigate the effects of early enteral nutrition (EEN) on the immune function and clinical outcome of patients with severe acute pancreatitis (SAP).METHODS:Patients were randomly allocated to receive EEN or delayed enteral nutrition (DEN).Enteral nutrition was started within 48 h after admission in EEN group,whereas from the 8 th day in DEN group.All the immunologic parameters and C-reactive protein (CRP) levels were collected on days 1,3,7 and 14 after admission.The clinical outcome variables were also recorded.RESULTS:Sixty SAP patients were enrolled to this study.The CD4+ T-lymphocyte percentage,CD4+/CD8+ ratio,and the CRP levels in EEN group became significantly lower than in DEN group from the 7 th day after admission.In contrast,the immunoglobulin G(IgG) levels and human leukocyte antigen-DR expression in EEN group became significantly higher than in DEN group from the 7 th day after admission.No difference of CD8+ T-lymphocyte percentage,IgM and IgA levels was found between the two groups.The incidences of multiple organ dysfunction syndrome,systemic inflammatory response syndrome,and pancreatic infection as well as the duration of intensive care unit stay were significantly lower in EEN group than in DEN group.However,there was no difference of hospital mortality between the two groups.CONCLUSION:EEN moderates the excessive immune response during the early stage of SAP without leading to subsequent immunosuppression.EEN can improve the clinical outcome,but not decrease the hospital mortality of SAP patients. | Jia-Kui Sun Xin-Wei Mu Wei-Qin Li Zhi-Hui Tong Jing Li Shu-Yun Zheng | 2013 | World Journal of Gastroenterology2013，19，6： | 106 |
| 2 | Predictive value of the Chinese group on the study of severe hepatitis B-acute-on-chronic liver failure score in the short-term prognosis of patients with hepatitis B virus-related acute-on-chronic liver failure显示文摘Background:As a large,prospective,multicenter study-based prognostic score for hepatitis B virus-related acute-on-chronic liver failure(HBV-ACLF),the Chinese group on the study of severe hepatitis B-acute-on-chronic liver failure score(COSSH-ACLFs),has been approved by some foreign scholars;however,its predictive value needs to be verified.This study investigated the predictive value of COSSH-ACLFs for short-term prognosis in Chinese patients with HBV-ACLF.Methods:This retrospective cohort study included 751 patients with HBV-ACLF admitted to the Fifth Medical Center of Chinese PLA General Hospital between January 2011 and December 2014.Spearman method was used to assess the correlation of COSSHACLFs with classical scores.Different COX multivariate regression models were used to confirm the relationship between COSSHACLFs and short-term prognosis in patients with HBV-ACLF,and stratified analysis was used to further verify the stability of this relationship.We compared the predictive powers of COSSH-ACLFs and other classical scores using area under the receiver operating characteristic curve(AUROC)and Z-test.Results:A total of 975 patients with HBV-ACLF were screened,and 751 were analyzed(623 male and 128 female).COSSH-ACLFs was the highest in patients with end-stage ACLF,followed by those with middle-and early-stage ACLF(H=211.8,P<0.001).In the fully adjusted model,COX multivariate regression analysis revealed that COSSH-ACLFs(as a continuous variable)was independently and positively correlated with mortality risk in patients with HBV-ACLF at 28 days(hazard ratio[HR]:1.37[1.22,1.53],P<0.001)and 90 days(HR:1.43[1.29,1.58],P<0.001).The same trend could be observed in the crude model and minimally adjusted model.The AUROCs of COSSH-ACLFs for 28-day and 90-day prognoses in patients with HBV-ACLF were 0.807 and 0.792,respectively,indicating a stronger predictive accuracy than those of classic models.Conclusions:COSSH-ACLFs,with a superior predictive accuracy compared with other classical scores,can strongly predict shortterm prognosis in Chinese patients with HBV-ACLF. | Jing-Jing Tong Wei Zhao Xiu-Ying Mu Xiang Xu Hai-Bin Su Xiao-Yan Liu Jing Chen Xing-Ran Zhai Yu Wang Jin-Hua Hu | 2019 | Chinese Medical Journal2019，，13： | 27 |
| 3 | Perfusion magnetic resonance imaging of the liver显示文摘Perfusion magnetic resonance imaging (MRI) studies quantify the microcirculatory status of liver parenchyma and liver lesions, and can be used for the detection of liver metastases, assessing the effectiveness of antiangiogenic therapy, evaluating tumor viability after anticancer therapy or ablation, and diagnosis of liver cirrhosis and its severity. In this review, we discuss the basic concepts of perfusion MRI using tracer kinetic modeling, the common kinetic models applied for analyses, the MR scanning techniques, methods of data processing, and evidence that supports its use from published clinical and research studies. Technical standardization and further studies will help to establish and validate perfusion MRI as a clinical imaging modality. | Choon Hua Thng Tong San Koh David J Collins Dow Mu Koh | 2010 | World Journal of Gastroenterology2010，16，13： | 15 |
| 4 | Molecular Characterization of Drug-Resistant Beijing Family Isolates of Mycobacterium Tuberculosis from Tianjin,China显示文摘Objective Tuberculosis remains a severe public health issue,and the Beijing family of mycobacterium tuberculosis(M. tuberculosis) is widespread in East Asia,especially in some areas in China,like Beijing and Tianjin.This study aimed at determining the mutation patterns of drug-resistant Beijing strains of M.tuberculosis isolated from Tianjin,China.Methods A total of 822 M.tuberculosis isolates were screened for drug resistance by an absolute concentration method and the genotype was identified by PCR.169 drug-resistant isolates of the Beijing family were analyzed for the potential mutations in the rpoB, katG,inhA promoter region and in rpsL,rrs and embB genes,which are associated with resistance to rifampin(RFP),isoniazid (INH),streptomycin(SM) and ethambutol(EMB) respectively by PCR and DNA sequencing.Results Fifty-eight out of 63 RFP-resistant isolates were found to carry the mutations within the 81-bp RFP resistance determining region(RRDR) of the rpoB gene and the most frequent mutations occurred at codon 531(44.4%),526(28.6%),and 516(7.9%) respectively.16 mutation patterns affecting 12 different codons around the RRDR of rpoB were found.Of 116 INH-resistant isolates,56(48.3%) had the mutation of katG 315(AGC→ACC)(Ser→Thr),3(2.6%) carried S315N(AGC→AAC) and 27(16.0%) had the mutation of inhA-15A→T.84 out of 122 SM-resistant isolates(68.9%) displayed mutations at the codons 43 or 88 with AAG→AGG(Lys→Arg) of the rpsL gene and 22(18.0%) with the mutations at positions 513A→C,516C→T or 905 A→G in the rrs gene.Of 34 EMB-resistant isolates,6 had mutation with M306V(ATG→GTG),3 with M306I(ATG→ATT),1 with M306I(ATG→ATA),1 with D328Y(GAT→TAT),1 with V348L(GTC→CTC),and 1 with G406S(GGC→AGC) in the embB gene.Conclusion These novel findings extended our understanding of resistance-related mutations in the Beijing strains of M.tuberculosis and may provide a scientific basis for development of new strategies for diagnosis and control of tuberculosis in China and other countries where Beijing strains are prevalent. | GUI-LIAN LI DE-FU ZHAO TONG XIE HAN-FANG JU CHENG MU HUI ZHAO XIE-XIU WANG | 2010 | Biomedical and Environmental Sciences2010，23，3： | 14 |
| 5 | Preliminary report on methane emissions from the Three Gorges Reservoir in the summer drainage period显示文摘Recently reported summertime methane (CH4) emissions (6.7 ± 13.3 mg CH4/(m2·hr)) from newly created marshes in the drawdown area of the Three Gorges Reservoir (TGR), China have triggered broad concern in academic circles and among the public. The CH4 emissions from TGR water surfaces and drawdown areas were monitored from 3rd June to 16th October 2010 with floating and static chambers and gas chromatography. The average CH4 emission flux from permanently flooded areas in Zigui, Wushan and Yunyang Counties was (0.33 ± 0.09) mg CH4/(m2·hr). In half of these hottest months of the year, the wilderness, cropland and deforested drawdown sites were aerobic and located above water level, and the CH4 emissions were very small, ranging from a sink at 0.12 mg CH4/(m2·hr) to a source at 0.08 mg CH4/(m2·hr) except for one mud-covered site after flood. Mean CH4 emission in flooded drawdown sites was 0.34 mg CH4/(m2·hr). The emissions from the rice paddy sites in the drawdown area were averaged at (4.86 ± 2.31) mg CH4/(m2·hr). Excepting the rice-paddy sites, these results show much lower emission levels than previously reported. Our results indicated considerable spatial and temporal variation in CH4 emissions from the TGR. Human activities and occasional events, such as flood, may also affect emission levels. Long-term CH4 measurements and modeling in a large region are necessary to accurately estimate greenhouse gas emissions from the TGR. | Fei Lu Le Yang Xiaoke Wang Xiaonan Duan Yujing Mu Wenzhi Song Feixiang Zheng Junfeng Niu Lei Tong Hua Zheng Yongjuan Zhou Jiangxiao Qiu Zhiyun Ouyang | 2011 | Journal of Environmental Sciences2011，23，12： | 13 |
| 6 | One-pot synthesis and characterization of a new, branched polycarbosilane bearing allyl groups显示文摘A highly branched polycarbosilane bearing allyl groups has been prepared by a one-pot synthesis with chloromethyltrichlor-osilane, chloromethylmethyldichlorosilane and allyl chloride as the starting materials. The resultant polymer, with the approximate formula [SiH1.2(CH3)0.71(CH2CH=CH2)0.09CH2]n, has been characterized by 1H, 13C, and 29Si NMR, GPC, TG and elemental analysis. It could be cross-linked thermally at 170℃in the absence of oxygen. Pyrolysis of the polymer gave a ceramic with a yield of about 70%. | Tian Hua Huang Zhao Ju Yu Xu Min He Mu He Huang Li Fu Chen Hai Ping Xia Li Tong Zhang | 2007 | Chinese Chemical Letters2007，18，6： | 9 |
| 7 | Load curve smoothing strategy based on unified state model of different demand side resources显示文摘Renewable energy based distributed generation(DG) has the potential to reach high penetration levels in the residential region. However, its integration at the demand side will cause rapid power fluctuations of the tieline in the residential region. The traditional generators are generally difficult to manage rapid power fluctuations due to their insufficient efficiency requirements and low responding speed. With an effective control strategy, the demand side resources(DSRs) including DGs, electric vehicles and thermostatically-controlled loads at thedemand side, are able to serve as the energy storage system to smooth the load fluctuations. However, it is a challenge to properly model different types of DSRs. To solve this problem, a unified state model is first developed to describe the characteristics of different DSRs. Then a load curve smoothing strategy is proposed to offset the load fluctuations of the tie-line of the residential region, where a control matrix deduced from the unified state model is introduced to manage the power outputs of different DSRs,considering the response order and the comfort levels.Finally, a residential region with households is used to validate the load curve smoothing strategy based on the unified state model, and the results show that the power fluctuation rate of the tie-line is significantly decreased.Meanwhile, comparative study results are shown to demonstrate the advantages of the unified state model based load curve smoothing strategy. | Mingshen WANG Yunfei MU Tao JIANG Hongjie JIA Xue LI Kai HOU Tong WANG | 2018 | Journal of Modern Power Systems and Clean Energy2018，6，3： | 8 |
| 8 | Analysis of In-hospital Neonatal Death in the Tertiary Neonatal Intensive Care Unit in China: A Multicenter Retrospective Study显示文摘 | Chen-Hong Wang Li-Zhong Du Xiao-Lu Ma Li-Ping Shi Xiao-Mei Tong Hong Liu Guo-Fang Ding Bin Yi Xin-Nian Pan Dan-Ni Zhong Ling Liu Mei Li Cui-Qing Li Shi-Wen Xia Hong-Yun Wang Ling He Kun Liang Xiao-Yu Zhou Shu-Ping Han Qin Lyu Yin-Ping Qiu Ruo-Bing Shan De-Zhi Mu Xiao-Hong Liu Si-Qi Zhuang Jing Guo Li Liu Jia-Jun Zhu Hong Xiong | 2016 | Chinese Medical Journal2016，，22： | 8 |
| 9 | Toxicity of Multi-Walled Carbon Nanotubes,Graphene Oxide,and Reduced Graphene Oxide to Zebrafish Embryos显示文摘Objective This study was aimed to investigate the toxic effects of 3 nanomaterials, i.e. multi-walled carbon nanotubes(MWCNTs), graphene oxide(GO), and reduced graphene oxide(RGO), on zebrafish embryos. Methods The 2-h post-fertilization(hpf) zebrafish embryos were exposed to MWCNTs, GO, and RGO at different concentrations(1, 5, 10, 50, 100 mg/L) for 96 h. Afterwards, the effects of the 3 nanomateria on spontaneous movement, heart rate, hatching rate, length of larvae, mortality, and malformations ls were evaluated. Results Statistical analysis indicated that RGO significantly inhibited the hatching of zebrafish embryos. Furthermore, RGO and MWCNTs decreased the length of the hatched larvae at 96 hpf. No obvious morphological malformation or mortality was observed in the zebrafish embryos after exposure to the three nanomaterials. Conclusion MWCNTs, GO, and RGO were all toxic to zebrafish embryos to influence embryos hatching and larvae length. Although no obvious morphological malformation and mortality were observed in exposed zebrafish embryos, further studies on the toxicity of the three nanomaterials are still needed. | LIU Xiao Tong MU Xi Yan WU Xiao Li MENG Li Xuan GUAN Wen Bi MA Yong Qiang SUN Hua WANG Cheng Ju LI Xue Feng | 2014 | Biomedical and Environmental Sciences2014，27，9： | 6 |
| 10 | Effects of 2'-O-methyl nucleotide on ligation capability of T4 DNA ligase显示文摘为了推进,理解结扎机制, T4 DNA 结扎效率上的 2-O-methyl 核苷酸(2 预兆) 的效果被调查。荧光回声精力转移试金被用来由 T4 DNA ligase 监视加入刻痕的进程。结果证明在刻痕的 5 结束和 3 结束的替换减少了在 48.7% | Bin Zhao Zhaoxue Tong Guojie Zhao Runqing Mu Hong Shang Yifu Guan | 2014 | Acta Biochimica et Biophysica Sinica2014，46，9： | 5 |
| 11 | Arbitrary cylindrical vector beam generation enabled by polarization-selective Gouy phase shifter显示文摘Cylindrical vector beams(CVBs),which possess polarization distribution of rotational symmetry on the transverse plane,can be developed in many optical technologies.Conventional methods to generate CVBs contain redundant interferometers or need to switch among diverse elements,thus being inconvenient in applications containing multiple CVBs.Here we provide a passive polarization-selective device to substitute interferometers and simplify generation setup.It is accomplished by reversing topological charges of orbital angular momentum based on a polarization-selective Gouy phase.In the process,tunable input light is the only condition to generate a CVB with arbitrary topological charges.To cover both azimuthal and radial parameters of CVBs,we express the mapping between scalar Laguerre–Gaussian light on a basic Poincaré sphere and CVB on a high-order Poincaré sphere.The proposed device simplifies the generation of CVBs enormously and thus has potential in integrated devices for both quantum and classic optical experiments. | JUNLIANG JIA KEPENG ZHANG GUANGWEI HU MAPING HU TONG TONG QUANQUAN MU HONG GAO FULI LI CHENG-WEI QIU PEI ZHANG | 2021 | Photonics Research2021，9，6： | 4 |
| 12 | Deep plug-and-play priors for spectral snapshot compressive imaging显示文摘We propose a plug-and-play(Pn P) method that uses deep-learning-based denoisers as regularization priors for spectral snapshot compressive imaging(SCI). Our method is efficient in terms of reconstruction quality and speed trade-off, and flexible enough to be ready to use for different compressive coding mechanisms. We demonstrate the efficiency and flexibility in both simulations and five different spectral SCI systems and show that the proposed deep Pn P prior could achieve state-of-the-art results with a simple plug-in based on the optimization framework. This paves the way for capturing and recovering multi-or hyperspectral information in one snapshot,which might inspire intriguing applications in remote sensing, biomedical science, and material science. Our code is available at: http://gffzz188fe103f8f1460as6bn0ofqk5wnc69nn.ffgz.tsg.suse.edu.cn/zsm1211/Pn P-CASSI. | SIMING ZHENG YANG LIU ZIYI MENG MU QIAO ZHISHEN TONG XIAOYU YANG SHENSHENG HAN XIN YUAN | 2021 | Photonics Research2021，9，2： | 4 |
| 13 | A Nonresonant Hybridized Electromagnetic-Triboelectric Nanogenerator for Irregular and Ultralow Frequency Blue Energy Harvesting显示文摘As a promising renewable energy source,it is a challenging task to obtain blue energy,which is irregular and has an ultralow frequency,due to the limitation of technology.Herein,a nonresonant hybridized electromagnetic-triboelectric nanogenerator was presented to efficiently obtain the ultralow frequency energy.The instrument adopted the flexible pendulum structure with a precise design and combined the working principle of electromagnetism and triboelectricity to realize the all-directional vibration energy acquisition successfully.The results confirmed that the triboelectric nanogenerator(TENG)had the potential to deliver the maximum power point of about 470μW while the electromagnetic nanogenerator(EMG)can provide 523 mW at most.The conversion efficiency of energy of the system reached 48.48%,which exhibited a remarkable improvement by about 2.96 times,due to the elastic buffering effect of the TENG with the double helix structure.Furthermore,its ability to collect low frequency wave energy was successfully proven by a buoy in Jialing River.This woke provides an effective candidate to harvest irregular and ultralow frequency blue energy on a large scale. | Weibo Xie Lingxiao Gao Lingke Wu Xin Chen Fayang Wang Daqiao Tong Jian Zhang Jianyu Lan Xiaobin He Xiaojing Mu Ya Yang | 2021 | Research2021，，1： | 4 |
| 14 | Design and Experiments of Biomimetic Stubble Cutter显示文摘 | Zhiyong Chang Wei Liu Jin Tong Li Guo Heng Xie Xiao Yang Haifeng Mu Donghui Chen | 2016 | Journal of Bionic Engineering2016，13，2： | 3 |
| 15 | On a Solution of the Quaternion Matrix Equation X-A B=C and Its Application显示文摘这篇论文首先学习复杂矩阵方程 X-AXB = C 的答案,借助于典型多项式获得方程的一个明确的答案,然后学习四元数矩阵方程 X-A X波浪字符 B = C 描绘矩阵方程的一个答案的存在,并且借助于四元数矩阵的真正的代表在明确的形式导出矩阵方程的靠近形式的答案。这篇论文也把应用给复杂矩阵方程 X-A (X 酒吧) B = C。 | Tong Song JIANG Mu Sheng WEI | 2005 | Acta Mathematica Sinica,English Series2005，21，3： | 3 |
| 16 | MicroRNA-145 plays a role in mitochondrial dysfunction in alveolar epithelial cells in lipopolysaccharide-induced acute respiratory distress syndrome显示文摘BACKGROUND: Acute respiratory distress syndrome (ARDS) causes substantial mortalities.Alveolar epithelium is one of the main sites of cell injuries in ARDS. As an important kind of microRNAs(miRNAs), microRNA-145 (miR-145) has been studied in various diseases, while its role in ARDS has notbeen investigated.METHODS: Lipopolysaccharide (LPS) was intratracheally instilled to establish a rat ARDS model.Cytokines from bronchoalveolar lavage fl uid (BALF) were measured using rat tumor necrosis factor-α andinterleukin-6 enzyme-linked immunosorbent assay kits (R&D Systems), and the pathological structureswere evaluated using hematoxylin and eosin (H&E) staining and transmission electron microscope;thelung miR-145 messenger RNA (mRNA) was detected using quantitative polymerase chain reaction.Bioinformatics focused on the target genes and possible pathways of gene regulation.RESULTS: A rat model of LPS-induced ARDS was successfully established. The miR-145was down-regulated in the LPS-induced ARDS lung, and mitochondrial dysfunction was observedin alveolar epithelial cells, most obviously at 72 hours after LPS. TargetScan and miRDB databaseswere used to predict the target genes of miR-145. A total of 428 overlapping genes were identifi ed,seven genes were associated with mitochondrial function, and Ogt, Camk2d, Slc8a3, and Slc25a25were verifi ed. Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways were enriched in themitogen-activated protein kinase (MAPK) signaling pathway, and Gene Ontology (GO) biologicalprocess was mainly enriched in signal transduction and transcription regulation.CONCLUSIONS: The miR-145 is down-regulated in LPS-induced ARDS, and affects itsdownstream genes targeting mitochondrial functions. | Yi Han Su-cheng Mu Jian-li Wang Wei Wei Ming Zhu Shi-lin Du Min Min Yun-jie Xu Zhen-ju Song Chao-yang Tong | 2021 | World Journal of Emergency Medicine2021，12，1： | 3 |
| 17 | Discovery of a novel 112-type iron-pnictide and La-doping induced superconductivity in Eu_(1-x)La_xFeAs_2(x=0–0.15)显示文摘We report the discovery and characterization of a novel 112-type iron pnictide Eu Fe As_2, with La-doping induced superconductivity in a series of Eu_(1-x)La_xFeAs_2. The polycrystalline samples were synthesized through solid state reaction method only within a very narrow temperature window around 1073 K.Small single crystals were also grown from a flux method with the size about 100 lm. The crystal structure was identified by single crystal X-ray diffraction analysis as a monoclinic structure with space group of P21/m. From resistivity and magnetic susceptibility measurements, we found that the parent compound Eu Fe As_2 shows distinct anomalies probably due to the Fe^(2+) related antiferromagnetic/structural phase transition near 110 K and the Eu^(2+) related antiferromagnetic phase transition near 40 K.La-doping suppressed both phase transitions to lower temperatures and induced superconducting transitions with a Tc^11 K for Eu_(0.85)La_(0.15) Fe As_2. | Jia Yu Tong Liu Bo-Jin Pan Bin-Bin Ruan Xiao-Chuan Wang Qing-Ge Mu Kang Zhao Gen-Fu Chen Zhi-An Ren | 2017 | Science Bulletin2017，62，3： | 3 |
| 18 | Superconductivity at 10.4 K in a novel quasi-one-dimensional ternary molybdenum pnictide K2Mo3As3显示文摘Here we report the discovery of the first ternary molybdenum pnictide based superconductor K_2Mo_3As_3.Polycrystalline samples were synthesized by the conventional solid state reaction method. X-ray diffraction analysis reveals a quasi-one-dimensional hexagonal crystal structure with(Mo_3 As_3)~2 àlinear chains separated by K^+ ions, similar as previously reported K_2Cr_3As_3, with the space group of P-6 m2(No. 187)and the refined lattice parameters a = 10.145(5) ? and c = 4.453(8) ?. Electrical resistivity, magnetic susceptibility, and heat capacity measurements exhibit bulk superconductivity with the onset Tcat 10.4 K in K_2Mo_3As_3 which is higher than the isostructural Cr-based superconductors. Being the same group VIB transition elements and with similar structural motifs, these Cr and Mo based superconductors may share some common underlying origins for the occurrence of superconductivity and need more investigations to uncover the electron pairing within a quasi-one-dimensional chain structure. | Qing-Ge Mu Bin-Bin Ruan Kang Zhao Bo-Jin Pan Tong Liu Lei Shan Gen-Fu Chen Zhi-An Ren | 2018 | Science Bulletin2018，63，15： | 2 |
| 19 | Positorn annihilation study on point defects in lead tungstate显示文摘A study on point defects in lead tungstate (PbWO4) by using positron annihilation lifetime method is presented. The measurement was carried out for the cases of untreated, vacuum-annealed, oxygen- annealed and La-doped PbWO4 crystals.It was found that the components τ2, which reflect the positron annihilation in point defects, are different from each other for each case. Some tentative models for the defects are discussed. | GU Mu TANG Xue-Feng TONG Hong-Yong LIANG Ling YAO Ming-Zhen CHEN Ling-Yan(Department of Physics, Tongji University, Shanghai 200092)LIAO Jing-Ying SHEN Ding-Zhong YIN Zhi-Wen(Laboratory of Functional Inorganic Materials, the Chinese Academy of Scien | 2000 | Nuclear Science and Techniques2000，11，2： | 2 |
| 20 | Consensus on the Prevention of Type 2 Diabetes in Chinese Adults显示文摘 | Yu-Zhen Tong Nan-Wei Tong Wei-Ping Teng Yi-Ming MU Jia-Jun Zhao Zhong-Yan Shan Guang Ning | 2017 | Chinese Medical Journal2017，，5： | 2 |
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