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| 1 | Endothelin-1 activation in pediatric patients undergoing surgical coarctation of the aorta repair显示文摘AIM To determine endothelin-1(ET-1)concentration before and after surgical coarctectomy and evaluate its association with left ventricular geometric change.METHODSA prospective,cohort study of 24 patients aged 2 d to 10years with coarctation of the aorta undergoing surgical repair.A sub-cohort of patients with age<1 mo was classified as'neonates'.Echocardiograms were performed just prior to surgery and in the immediate post-op period to assess left ventricle mass index and relative wall thickness(RWT).Plasma ET-1 levels were assessed at both time points.Association between ET-1 levels and ventricular remodeling was assessed.RESULTSPatients<1 year demonstrated higher pre-op ET-1 than post-op(2.8 pg/m L vs 1.9 pg/m L,P=0.02).Conversely,patients>1 year had no change in ET-1 concentration before and after surgery(1.1 vs 1.4,NS).Pre-op,patients<1 year demonstrated significantly higher ET-1 than older children(2.8 vs 1.1,P=0.001).Post-op there was no difference between the age groups(1.9 vs 1.4,NS).Neither RWT nor left ventricle mass index(LVMI)varied from pre-op to post-op.The subset of neonates showed a strong positive correlation between pre-op ET-1 and RWT(r=0.92,P=0.001).Patients with ET-1>2 pg/m L preop demonstrated higher LVMI(65.7 g/m^(2.7) vs 38.5 g/m^(2.7),P=0.004)and a trend towards higher RWT(45%vs39%,P=0.07)prior to repair than those with lower ET-1concentration.CONCLUSIONET-1 concentration is significantly variable in the perioperative period surrounding coarctectomy.Older children and infants have different responses to surgical repair suggesting different mechanisms of activation. | Benjamin Steven Frank Tracy T Urban Suhong Tong Courtney Cassidy Max B Mitchell Christopher S Nichols Jesse A Davidson | 2017 | World Journal of Cardiology2017，9，12： | 2 |
| 2 | Texture and microstructure of thin copper films显示文摘 | Tracy D P Knorr D B | 1993 | Journal of Electronic Materials1993，22，6： | 1 |
| 3 | ILAE Treatment Guidelines:evidence-based analysis of antiepileptic drug efficacy andeffectiveness as initial monotherapy for epileptic seizures andsyndromes显示文摘 | Tracy G Ben M Blaise B | 2006 | Epilepsia2006，47，7： | 1 |
| 4 | The distribution of the Burmese python,Python molurus bivittatus显示文摘 | David G B Tracy M B | 2008 | The Bulletin of the Chicago Herpetological Society2008，43，： | 1 |
| 5 | Efficacy and safety of levetiracetam in children with partial seizures: an open-label trial 显示文摘 | Tracy A Glauser B John M | 2002 | Epilepsia2002，43，5： | 1 |
| 6 | Real- world intranets in 2010:SWOT analysis显示文摘 | Tracy B | 2010 | Busi ness Information Review2010，27，： | 1 |
| 7 | Increased environmental gamma-ray dose rate during precipitation:a strong correlation with contributing air mass显示文摘 | Mercier J F Tracy B L Amours R d' | | 0，，： | 1 |
| 8 | The distribution of the Burmese python,Python bivittatus显示文摘 | David G B Tracy M B | 2010 | The Bulletin of the Chicago Herpetological Society2010，45，： | 1 |
| 9 | Microstructure and porosity of silica xerogel monoliths prepared by the fast sol-gel method显示文摘 | Tracy R B Vikkl B | 2000 | Sol-Gel Sci Techn2000，17，： | 1 |
| 10 | Effect of surfactant and particle size reduction on hydrolysis of deinking sludge and nonrecyclable newsprint显示文摘 | Duff Sheldon J B Moritz John W Casavant Tracy E | 1995 | Biotechnology and Bioengineering1995，45，3： | 1 |
| 11 | Seed bank diversity in grazing lands of the Northeast United States显示文摘 | Tracy B F Sanderson M A | 2000 | Range Management2000，53，： | 1 |
| 12 | Pain management in older adults显示文摘 | TRACY B SEAN MORRISON R | 2013 | Clin Ther2013，35，11： | 1 |
| 13 | Disturbance persistence in managed grasslands:Shifts in above ground community structure and the weed seed bank显示文摘 | RENNE I J TRACY B F | 2007 | Plant Ecology2007，190，： | 1 |
| 14 | Global Analysis of Host-Pathogen Interactions that Regulate Early-Stage HIV-1 Replication显示文摘 | Renate K?nig Yingyao Zhou Daniel Elleder Tracy L. Diamond Ghislain M.C. Bonamy Jeffrey T. Irelan Chih-yuan Chiang Buu P. Tu Paul D. De Jesus Caroline E. Lilley Shannon Seidel Amanda M. Opaluch Jeremy S. Caldwell Matthew D. Weitzman Kelli L. Kuhen Sourav B | 2008 | Cell2008，，1： | 1 |
| 15 | Physical vapor transport growth of large AlN crystals 显示文摘 | TRACY W CHRIS C R SINGH N B | 2003 | J of Crystal Growth2003，250，1： | 1 |
| 16 | A Review of Microstructure in Vapor Deposited Copper Thin Films 显示文摘 | Knott D B Tracy D P | 1995 | Materials Chemistry and Physics1995，41，3： | 1 |
| 17 | Investigating the Effect of Carbon Shape on Virus Adsorption 显示文摘 | Traci P Gail M B Marit J | 2000 | Environ Sci Technol2000，34，13： | 1 |
| 18 | Induction of angiosarcoma by c-erbB transducing virus 显示文摘 | Tracy S E Woda B E Robinson H L | 1985 | J Virol1985，54，： | 1 |
| 19 | Developmental changes associated with divergent selection for rind penetrometer resistance in the MoSCSSS maize synthetic显示文摘 | Abedon B G Darrah L L Tracy W F | 1999 | Crop Science1999，39，： | 1 |
| 20 | Analysis of plutonium oxide surrogate residue using laser-induced breakdown spectroscopy 显示文摘 | Zheng H B Yu F Tracy M | 2008 | Spectrochimica Acta Part B2008，63，8： | 1 |
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