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| 1 | Petrogenesis of the Neopro-terozoic bimodal volcanic rocks along the western margin of the Yangtze Block:New constraints from Hf isotopes and Fe/Mn ratios显示文摘High-precision major element and Hf isotope data are reported for the Neoproterozoic Suxiong volcanic rocks along the western margin of the Yangtze Block. These volcanic rocks have variable εHf(T) values and Fe/Mn ratios. The relatively primitive basalts have high Fe/Mn ratios and high Hf-Nd isotopic compositions, indicating that they were generated by partial melting of garnet clinopyroxene in mantle plume at high pressure. Thus, the Suxiong basalts are genetically related to the proposed Neoproterozoic super-plume. On the contrary, a few differentiated basalts have low Fe/Mn ratios and low Hf-Nd isotopic compositions. They are likely to experience assimilation-fractional crystallization process. The Suxiong rhyolites have consistent Hf and Nd model ages of 1.3―1.4 Ga. They are likely generated by shallow dehydration melting of pre-existing young arc igne-ous rocks associated with the basaltic underplating/intrusion in a continental rift. | LI Xianhua QI Changshi LIU Ying LIANG Xirong TU Xianglin XlE Liewen YANG Yueheng | 2005 | Chinese Science Bulletin2005，50，21： | 91 |
| 2 | Clinical Features of Adult/Adolescent Atopic Dermatitis and Chinese Criteria for Atopic Dermatitis显示文摘 | Ping Liu Yan Zhao Zhang-Lei Mu Qian-Jin Lu Qian-Jin L U Li Zhang Xu Yao Min Zheng Yi-Wen Tang Xin-Xiano Lu Xiu-Juan xia You-Kun Lin Yu-Zhen Li Cai-Xia Tu Zhi-Rong Yao Jin-Hua Xu Wei Li Wei Lai Hui-Min Yang Hong-Fu Xie Xiu-Ping Han Zhi-Qiang Xie Xiang Nong Zai-Pei Guo Dan-Qi Deng Tong-Xin Shi Jian-Zhong Zhang | 2016 | Chinese Medical Journal2016，，7： | 64 |
| 3 | Immune suppression in chronic hepatitis B infection associated liver disease: A review显示文摘Hepatitis B virus(HBV) infection is one the leading risk factors for chronic hepatitis, liver fibrosis, cirrhosis and hepatocellular cancer(HCC), which are a major global health problem. A large number of clinical studies have shown that chronic HBV persistent infection causes the dysfunction of innate and adaptive immune response involving monocytes/macrophages, dendritic cells, natural killer(NK) cells, T cells. Among these immune cells, cell subsets with suppressive features have been recognized such as myeloid derived suppressive cells(MDSC),NK-reg, T-reg, which represent a critical regulatory system during liver fibrogenesis or tumourigenesis. However, the mechanisms that link HBVinduced immune dysfunction and HBV-related liver diseases are not understood.In this review we summarize the recent studies on innate and adaptive immune cell dysfunction in chronic HBV infection, liver fibrosis, cirrhosis, and HCC, and further discuss the potential mechanism of HBV-induced immunosuppressive cascade in HBV infection and consequences. It is hoped that this article will help ongoing research about the pathogenesis of HBV-related hepatic fibrosis and HBV-related HCC. | Tian-Yang Li Yang Yang Guo Zhou Zheng-Kun Tu | 2019 | World Journal of Gastroenterology2019，25，27： | 69 |
| 4 | Transmission Dynamics of an Outbreak of the COVID-19 Delta Variant B.1.617.2——Guangdong Province,China,May-June 2021显示文摘On May 21,2021,a local case of coronavirus disease 2019(COVID-19)was confirmed in a 75-year-old woman(experienced onset of symptoms on May 18)in Liwan District,Guangzhou City,Guangdong Province,China.The number of infections has increased in the following 10 days and led to 5 generations of transmission. | Meng Zhang Jianpeng Xiao Aiping Deng Yingtao Zhang Yali Zhuang Ting Hu Jiansen Li Hongwei Tu Bosheng Li Yan Zhou Jun Yuan Lei Luo Zimian Liang Youzhi Huang Guoqiang Ye Mingwei Cai Gongli Li Bo Yang Bin Xu Ximing Huang Yazun Cui Dongsheng Ren Yanping Zhang Min Kang Yan Li | 2021 | China CDC weekly2021，3，27： | 51 |
| 5 | Screening for main components associated with the idiosyncratic hepatotoxicity of a tonic herb, Polygonum multiflorum显示文摘典型药用的植物的主要成分,蓼 multiflorum (用汉语的 Heshouwu ) ,那导致特质的肝损害仍然保持不清楚。我们的以前的工作证明了有 lipopolysaccharide (LPS ) 的无毒的剂量和 Heshouwu 的治疗学的剂量的 cotreatment 能在老鼠导致肝损害,而独唱治疗不能导致看得见的损害。在现在的工作,用成分大美人和敲门在里面策略,我们发现 Heshouwu 的乙醇醋酸盐(EA ) 摘录在对待 LPS 的老鼠显示了可比较的特质的 hepatotoxicity 到整个摘录。结果显示血浆丙氨酸 aminotransferase, aspartate aminotransferase,和肝 histologic 的重要举起变化,而另外的分开的部分没能导致肝损害。有另外的分开的部分的 EA 摘录的混合在对待 LPS 的老鼠导致了可比较的特质的 hepatotoxicity 到整个摘录。化学分析进一步揭示了那 2,3,5,4-tetrahydroxy trans-stilbene-2-O -- 配糖物(trans-SG ) 和它的 cis 异构体是在 EA 的二主要混合物摘录。而且,孤立的 cis- ,并且不它的 trans 异构体,显示的可比较的特质的 hepatotoxicity 到在对待 LPS 的老鼠的 EA 摘录。cis-SG 的更高的内容从与收集的将军相比与 Heshouwu 联系的实际的肝沉醉病人在 Heshouwu 白酒或准备被检测样品。另外,血浆 metabolomics 分析证明 cis-SG-disturbing 充实显著地不同于的小径在对待 LPS 的老鼠的 trans-SG。所有这些结果建议 cis-SG 仔细与 Heshouwu 的特质的 hepatotoxicity 被联系。认为 trans-SG 的 cis-trans 异构化被紫外光或日光调停,我们的调查结果为在药发现控制 photoisomerization 并且为 Heshouwu 和芪相关的药的临床的使用用作参考。 | Chunyu Li Ming Niu Zhaofang Bai Congen Zhang Yanling Zhao Ruiyu Li Can Tu Huifang Li Jing Jing Yakun Meng Zhijie Ma Wuwen Feng Jinfa Tang Yun Zhu Jinjie Li Xiaoya Shang Zhengsheng Zou Xiaohe Xiao Jiabo Wang | 2017 | Frontiers of Medicine2017，11，2： | 41 |
| 6 | Helicobacter pylori vacA genotypes and cagA status and their relationship to associated diseases显示文摘INTRODUCTIONHelicobacter pylori(H.pylori)is a major causativebacterium of chronic gastritis,peptic ulcer and mucosa-associated lymphoid tissue lymphoma in humans,andassociated with an increased risk of gastric cancer. | Hou P Tu ZX Xu GM Gong YF Ji XH Li ZS | 2000 | World Journal of Gastroenterology2000，6，4： | 27 |
| 7 | Digestive tract reconstruction using isoperistaltic jejunumlater-cut overlap method after totally laparoscopic total gastrectomy for gastric cancer: Short-term outcomes and impact on quality of life显示文摘AIM To evaluate the short-term outcomes and quality of life(Qo L) in gastric cancer patients undergoing digestive tract construction using the isoperistaltic jejunum-latercut overlap method(IJOM) after totally laparoscopic total gastrectomy(TLTG).METHODS A total of 507 patients who underwent laparoscopic gastrectomy(D2) from January 2014 to March 2016 were originally included in the study. The patients were divided into two groups to undergo digestive tract construction using either IJOM after TLTG(group T, n = 51) or Roux-en-Y anastomosis after laparoscopic-assisted total gastrectomy(LATG)(group A, n = 456). The short-term outcomes and Qo L were compared between the two groups after 1:2 propensity-score matching(PSM). We used a questionnaire to assess Qo L.RESULTS Before matching, age, sex, tumor size, tumor location, preoperative albumin and blood loss were significantly different between the two groups(P < 0.05). After PSM, the patients were well balanced in terms of their clinicopathological characteristics, although both blood loss and in-hospital postoperative days in group T were significantly lower than those in group A(P < 0.05). After matching, group T reported better Qo L in the domains of pain and dysphagia. Among the items evaluating pain and dysphagia, group T tended to report better Qo L('Have you felt pain' and 'Have you had difficulty eating solid food')(P < 0.05).CONCLUSION The IJOM for digestive tract reconstruction after TLTG is associated with reduced blood loss and less pain and dysphagia, thus improving Qo L after laparoscopic gastrectomy. | Ze-Ning Huang Chang-Ming Huang Chao-Hui Zheng Ping Li Jian-Wei Xie Jia-Bin Wang Jian-Xian Lin Jun Lu Qi-Yue Chen Long-Long Cao Mi Lin Ru-Hong Tu Ju-Li Lin | 2017 | World Journal of Gastroenterology2017，23，39： | 27 |
| 8 | Magnesium lithospermate B possesses inhibitory activity on Na^+,K^+-ATPase and neuroprotective effects against ischemic stroke显示文摘瞄准:如果镁 lithospermate B (MLB ) 从 Danshen 提取了,检验,鼠尾草植物 miltiorrhiza 的弄干的根,当为经由一样的分子的机制的这繁体中文植物的 cardiactherapeutic 效果负责的一个活跃部件触发了 bycardiac glycosides,可以行动,例如 ouabain 和异羟基洋地黄毒苷。而且,如果,我们想要测试 MLB 对 ischemic 的 provideneuroprotection 可以是为心脏的 glycosides 观察了摸。方法:在 MLB 和 ouabain 之间的类似 inthe 化学药品结构和分子的配置被分析。Na+ 上的 MLB 和 ouabain 的 Theinhibition 力量,一个商业产品的 K+-ATPase 活动,也, asin 从老鼠大脑和心纸巾净化了膜部分,被检验,对 ischemic 击的 MLB 的 compared.Neuroprotective 效果也用一个外皮的基于 brainslice 的试金模型被评估。结果:商业 Na+ 上的剂量依赖者抑制,为 ouabain 的到那的 K+-ATPaseequivalent 为 MLB 被观察近似由重量的半剂量。ouabain 和 MLB 的 Thisrelative 力量也在 Na+ 上为他们的抑制被观察,从老鼠纸巾净化的 K+-ATPase activityof 血浆膜,尽管这 2 个禁止者有点在这些粗略的摘录展出了 lowercompetence。在 ischemic 沙鼠大脑,与 MLB significantlyreduced 处理以后梗塞尺寸,由 2,3,5-triphenyltetrazolium 氯化物染色设想了, byapproximately 55% 什么时候与控制组相比。结论:这些结果显然 suggestthat Danshen 的心脏的治疗学的效果应该部分至少被归因于 Na+ ,由 MLB 的 K+-ATPase,和那 MLB 的 effectiveinhibition 在 gerbilssubjected 提供 anti-ischemic neuroprotection 给焦点的局部缺血和灌注。 | Jason TC TZEN Tzyy-rong JINN Yi-ching CHEN Feng-yin LI Fu-chou CHENG Li-shian SHI Hank KH SHE Balance CM CHEN Vic HSIEH Mu-lin TU | 2007 | Acta Pharmacologica Sinica2007，28，5： | 25 |
| 9 | Effect of oxidization on enrichment behavior of TiO_2 in titanium-bearing slag显示文摘Due to the dispersed distribution of the titanium component in various mineral phases and very fine grain size, it is difficult to recover the titanium component from the slag. In order to utilize titanium resources, selective enriching and selective growing of the titanium component from the molten slag is expected. In this paper, the selection of the best tita- nium enrichment phase and the effect of oxidization on the enrichment of titanium by blowing air into the molten slag were studied. The results showed that through oxidizing the slag, the content of the perovskite phase increases while that of the other titanium-bearing mineral phases decreases until they disappear. Most titania resources were enriched into the perovskite phase and increase in size. The process of enrichment and growth is easily carried out. | WANG Mingyu LI Liaosha ZHANG Li ZHANG Linnan TU Ganfeng SUI Zhitong | 2006 | Rare Metals2006，25，2： | 23 |
| 10 | Characteristics of abnormal menstrual cycle and polycystic ovary syndrome in community and hospital populations显示文摘背景 Polycystic 卵巢症候群( PCOS )被认为是在在遗体 unclear.We 试图在社区和医院病人 populations.Methods 女人与 PCOS 分析反常月经周期和他们的协会的特征与的 PCOS 的病原学的一个反常月经周期的繁殖 age.The 参与的女人的最普通的内分泌的混乱在从 reproductiv 获得的北京和 506 个门诊病人的社区从 2111 个永久女居民识别的 PCOS 21 天;21-34 天;35-60 天;并且在每个组的 60 days.Women 用一张问询表被会见包括年龄估计因素,月经初潮的年龄,月经周期历史,相关家庭历史,并且修改了 score.All 女人收到了的 Ferriman-Gallwey ( mF-G ) transvaginal 超声扫描和为 0.05 的二尾巴的 P 价值在社区人口被认为 significant.Results 的内分泌的 evaluation.A 拿的有的 fasting 血样品,反常月经周期的流行是27.19%( 574/2111 ) PCOS 在的 .The | MA Yan-min LI Rong QIAO Jie ZHANG Xiao-wei WANG Shu-yu ZHANG Qiu-fang LI Li TU Bin-bin ZHANG Xue | 2010 | Chinese Medical Journal2010，，16： | 22 |
| 11 | Cervical Infection of Oncogenic Human Papillomavirus(HPV) Types in Beijing,China显示文摘Objective This study was designed to determine the prevalence of oncogenic human papillomavirus(HPV) in cervical infections in Beijing,China,and to investigate the odds ratio(OR) of HPV single and multiple infections in abnormal cytology.Methods A total of 19,018 specimens from outpatients in the department of obstetric and gynecology were collected.They were detected using high-risk HPV genotyping real-time polymerase chain reaction(PCR) kit and analyzed by ThinP rep cytology test for cervical pathological diagnosis.HPV prevalence,age-specific prevalence,and OR of each type of HPV in abnormal cytology were analyzed.Results Overall,19.1%(3,623/19,018) of the individuals were positive for HPV infection,14.9%(2,833/19,018) were positive for a single HPV type,and 4.2%(790/19,018) were positive for multiple types.Among the 3,623 HPV-positive individuals,the most predominant HPV types were HPV52(4.4%,834/19,018),HPV16(3.7%,710/19,018),and HPV58(3.4%,644/19,018).The OR of multiple infections and single infection differed significantly among disease severities.The OR of dual infection was higher than that of each of the two single infection types,respectively.Conclusion HPV prevalence in the outpatients was 19.1%,and the most predominant HPV types in the study were HPV52,HPV16,and HPV58.Women with multiple infectionswere more likely to have abnormal cytology. | LI Ying HUANG Ke JI Pei Li SONG Lei LIU Hong Tu | 2016 | Biomedical and Environmental Sciences2016，29，10： | 22 |
| 12 | The pharmacology, toxicology and therapeutic potential of anthraquinone derivative emodin显示文摘Emodin(1, 3, 8-trihydroxy-6-methylanthraquinone) is a derived anthraquinone compound extracted from roots and barks of pharmaceutical plants, including Rheum palmatum, Aloe vera, Giant knotweed, Polygonum multiflorum and Polygonum cuspidatum. The review aims to provide a scientific summary of emodin in pharmacological activities and toxicity in order to identify the therapeutic potential for its use in human specific organs as a new medicine. Based on the fundamental properties, such as anticancer, anti-inflammatory, antioxidant, antibacterial, antivirs, anti-diabetes, immunosuppressive and osteogenesis promotion, emodin is expected to become an effective preventive and therapeutic drug of cancer, myocardial infarction, atherosclerosis, diabetes, acute pancreatitis, asthma, periodontitis, fatty livers and neurodegenerative diseases. This article intends to provide a novel insight for further development of emodin, hoping to reveal the potential of emodin and necessity of further studies in this field. | CUI Ya CHEN Liu-Jing HUANG Tu YING Jian-Qiong LI Juan | 2020 | Chinese Journal of Natural Medicines2020，18，6： | 23 |
| 13 | Increased pretreatment levels of serum LDH and ALP as poor prognostic factors for nasopharyngeal carcinoma显示文摘Serum enzymes that play potential roles in tumor growth have recently been reported to have prognostic relevance in a diverse array of tumors.However,prognosis-related serum enzymes are rarely reported for nasopharyngeal carcinoma(NPC).To clarify whether the level of serum enzymes is linked to the prognosis of NPC,we reviewed the pretreatment data of lactate dehydrogenase(LDH),alkaline phosphatase (ALP),and glutamyl transferase (GGT) in 533 newly diagnosed NPC patients who underwent radical radiotherapy between May 2002 and October 2003 at Sun Yat-sen University Cancer Center.Patients were grouped according to the upper limit of normal values of LDH,ALP,and GGT.The Kaplan-Meier method and log-rank test were used for selecting prognostic factors from clinical characteristics and serum enzymes,and the chi-square test was applied to analyze the relationships of clinical characteristics and serum enzymes.Finally,a Cox proportional hazards model was used to identify the independent prognostic factors.We found that increased levels of LDH had poor effects on both overall survival and distant metastasis-free survival(P=0.009 and 0.035,respectively),and increased pretreatment level of serum ALP had poor effects on both overall survival and local recurrence-free survival(P=0.037 and 0.039,respectively).In multivariate analysis,increased LDH level was identified as an independent prognostic factor for overall survival.Therefore,we conclude that increased pretreatment serum LDH and ALP levels are poor prognostic factors for NPC. | Guo Li Jin Gao Ya-Lan Tao Bing-Qing Xu Zi-Wei Tu Zhi-Gang Liu Mu-Sheng Zeng Yun-Fei Xia | 2012 | Chinese Journal of Cancer2012，31，4： | 21 |
| 14 | Infliximab monotherapy for Chinese patients with moderate to severe plaque psoriasis: a randomized, double-blind, placebo-controlled multicenter trial显示文摘 | YANG Hai-zhen WANG Ke JIN Hong-zhong GAO Tian-wen XIAO Sheng-xiang XU Jin-hua WANG Bao-xi ZHANG Fu-ren LI Chun-yang LIU Xiao-ming TU Cai-xia JI Su-zhen SHEN Yang ZHU Xue-jun | 2012 | Chinese Medical Journal2012，，11： | 20 |
| 15 | Degradation of pyrene by immobilized microorganisms in saline-alkaline soil显示文摘Biodegradation of polycyclic aromatic hydrocarbons(PAHs) is very difficult in saline-alkaline soil due to the inhibition of microbial growth under saline-alkaline stress.The microorganisms that can most effectively degrade PAHs were screened by introducing microorganisms immobilized on farm byproducts and assessing the validity of the immobilizing technique for PAHs degradation in pyrene-contaminated saline-alkaline soil.Among the microorganisms examined,it was found that Mycobacterium sp.B2 is the best,and can degrade 82.2% and 83.2% of pyrene for free and immobilized cells after 30 days of incubation.The immobilization technique could increase the degradation of pyrene significantly,especially for fungi.The degradation of pyrene by the immobilized microorganisms Mucor sp.F2,fungal consortium MF and co-cultures of MB+MF was increased by 161.7%(P < 0.05),60.1%(P < 0.05) and 59.6%(P < 0.05) after 30 days,respectively,when compared with free F2,MF and MB+MF.Scanning electron micrographs of the immobilized microstructure proved the positive effects of the immobilized microbial technique on pyrene remediation in salinealkaline soil,as the interspace of the carrier material structure was relatively large,providing enough space for cell growth.Co-cultures of different bacterial and fungal species showed different abilities to degrade PAHs.The present study suggests that Mycobacterium sp.B2 can be employed for in situ bioremediation of PAHs in saline-alkaline soil,and immobilization of fungi on farm byproducts and nutrients as carriers will enhance fungus PAH-degradation ability in saline-alkaline soil. | Shanxian Wang Xiaojun Li Wan Liu Peijun Li Lingxue Kong Wenjie Ren Haiyan Wu Ying Tu | 2012 | Journal of Environmental Sciences2012，24，9： | 19 |
| 16 | Diffusion tensor imaging assesses white matter injury in neonates with hypoxic-ischemic encephalopathy显示文摘With improvements in care of at-risk neonates, more and more children survive. This makes it increasingly important to assess, soon after birth, the prognosis of children with hypoxic-ischemic encephalopathy. Computed tomography, ultrasound, and conventional magnetic resonance imaging are helpful to diagnose brain injury, but cannot quantify white matter damage. In this study, ten full-term infants without brain injury and twenty-two full-term neonates with hypoxic-ischemic encephalopathy(14 moderate cases and 8 severe cases) underwent diffusion tensor imaging to assess its feasibility in evaluating white matter damage in this condition. Results demonstrated that fractional anisotropy, voxel volume, and number of fiber bundles were different in some brain areas between infants with brain injury and those without brain injury. The correlation between fractional anisotropy values and neonatal behavioral neurological assessment scores was closest in the posterior limbs of the internal capsule. We conclude that diffusion tensor imaging can quantify white matter injury in neonates with hypoxic-ischemic encephalopathy. | Hong-xin Li Xing Feng Qian Wang Xuan Dong Min Yu Wen-juan Tu | 2017 | Neural Regeneration Research2017，12，4： | 19 |
| 17 | Palmitic acid induces autophagy in hepatocytes via JNK2 activation显示文摘 | Qian-qian TU Rui-ying ZHENG Juan LI Liang HU Yan-xin CHANG Liang LI Min-hong LI Ruo-yu WANG Dan-dan HUANG Meng-chao WU He-ping HU Lei CHEN Hong-yang WANG | 2014 | Acta Pharmacologica Sinica2014，35，4： | 18 |
| 18 | Expression of phosphatidylinositol-3 kinase and effects of inhibitor Wortmannin on expression of tumor necrosis factor-α in severe acute pancreatitis associated with acute lung injury显示文摘BACKGROUND: Acute lung injury(ALI) is a common and serious complication of severe acute pancreatitis(SAP). The study aimed to investigate the protective effect and mechanism of phosphatidylinositol-3 kinase(PI3K) inhibitor Wortmannin in SAP associated with ALI.METHODS: Ninety rats were randomly divided into three groups: sham operation(SO) group(n=30), SAP group(n=30), and SAP+Wortmannin(SAP+W) group(n=30). SAP model was induced by retrograde injection of 4% sodium taurocholate into the biliopancreatic duct of rats. The rate of lung water content, myeloperoxidase(MPO), matrix metalloproteinase 9(MMP-9), protein kinase B(PKB), abdphosphorylation of protein kinase B(P-PKB) activity in the lung tissue were evaluated.RESULTS: In the SAP group, the p-PKB expression in the lung tissue began to rise at 3 hours after modeling, and peaked at 12 hours(P<0.05); the rate of lung water content, MPO and TNF-α activity were also gradually increased, and the degree of lung lesion gradually increased(P<0.05). In the SAP+Wortmannin group, the p-PKB expression in the lung tissue began to rise at 3 hours after modeling, and peaked at 12 hours; it was higher than that in the SO group(P<0.05), but significantly lower than that in the SAP group(P<0.05). The rest indicators in the SAP+Wortmannin group were also significantly decreased as compared with the SAP group(P<0.05).CONCLUSIONS: The expression of phosphatidylinositol-3 kinase/protein kinase B was elevated in severe pancreatitis rats with lung injury. This suggested that PI3 K signal transduction pathway is involved in the control and release of proinfl ammatory cytokines TNF-α, which may play an important role in the pathogenesis of severe acute pancreatitis associated with lung injury. This finding indicated that Wortmannin can block the PI3 K signal transduction pathway, and inhibit the release of infl ammatory factor TNF-α. | Ming Wei Yan-jie Gong Ling Tu Jia Li Ying-hong Liang Yi-hua Zhang | 2015 | World Journal of Emergency Medicine2015，6，4： | 18 |
| 19 | Intercropping with Solanum nigrum and Solanum photeinocarpum from Two Ecoclimatic Regions Promotes Growth and Reduces Cadmium Uptake of Eggplant Seedlings显示文摘Soil contamination by heavy metals is a serious environmental problem worldwide, and reduction of heavy metal accumulation in vegetables grown on contaminated land is a matter of urgency. A pot experiment was conducted to study the effects of intercropping with the Cd hyperaccumulators Solanum nigrum and Solanum photeinocarpum from two ecoclimatic regions, Ya'an and Chengdu,Sichuan Province, China, on the growth and cadmium(Cd) uptake of eggplant(Solanum melongena L.). The biomass, photosynthetic pigment contents, and activities of antioxidant enzymes of eggplant were enhanced by intercropping. The biomass of eggplant was the highest after intercropping with S. photeinocarpum from Ya'an, but did not differ significantly from that after intercropping with S. nigrum from Chengdu. The shoot Cd content of eggplant was significantly reduced by intercropping with the hyperaccumulators,which ranked as follows: S. nigrum from Chengdu > S. nigrum from Ya'an > S. photeinocarpum from Chengdu > S. photeinocarpum from Ya'an, with the decreases being 19.60%, 14.36%, 9.66%, and 6.42%, respectively, as compared with the control. The lowest shoot Cd content and translocation factor of eggplant were attained after intercropping with S. nigrum from Chengdu. Therefore, it was feasible to intercrop eggplant with S. nigrum and S. photeinocarpum on Cd-contaminated soil. | TANG Yi HE Juan YU Xuena XIE Yongdong LIN Lijin SUN Guochao LI Huanxiu LIAO Mingan LIANG Dong XIA Hui WANG Xun ZHANG Jing LIU Zejing TU Lihua LIU Li | 2017 | Pedosphere2017，27，3： | 17 |
| 20 | Hepatitis B virus infection:A favorable prognostic factor for intrahepatic cholangiocarcinoma after resection显示文摘AIM: To study the prognostic factors for intrahepatic cholangiocarcinoma (ICC) and evaluate the impact of chronic hepatitis B virus (HBV) infection on survival rate of ICC patients. METHODS: A total of 155 ICC patients who underwent macroscopic curative resections (R0 and R1) were enrolled in this retrospective study and divided into group A with HBV infection and group B without HBV infection according to their chronic HBV infection, represented by positive hepatitis B surface antigen (HBsAg) in serum or in liver tissue. Clinicopathological characteristics and survival rate of the patients were evaluated. RESULTS: All patients underwent anatomical resection. Their 1- and 3-year survival rates were 60.6% and 32.1%, respectively. Multivariate analyses revealed that HBV infection, hepatolithiasis, microscopic satellite lesion, and lymphatic metastasis were the independent prognostic factors for the survival rate of ICC patients. The median disease-free survival time of the patients was 5.0 mo. The number of tumors, microscopic satellite lesion, and vascular invasion were the independent prognostic factors for the disease-free survival rate of the patients. The prognostic factors affecting the survival rate of ICC patients with HBV infection and those without HBV infection were not completely consistent. Alkaline phosphatase > 119 U/L, microscopic satellite lesion, vascular invasion, and lymphatic metastasis were the independent factors for the patients with HBV infection, while rglutamyltransferase > 64 U/L, microscopic satellite lesion, and poor tumor differentiation were the independent factors for the patients without HBV infection. CONCLUSION: HBV infection is a valuable clinical factor for predicting tumor invasiveness and clinical outcome of ICC patients. ICC patients with HBV infection should be distinguished from those without HBV infection because they have different clinicopathological characteristics, prognostic factors and outcomes after surgical resection. | Hua-Bang Zhou Hui Wang Yu-Qiong Li Shuang-Xi Li Hao Wang Dong-Xun Zhou Qian-Qian Tu Qing Wang Shan-Shan Zou Meng-Chao Wu He-Ping Hu | 2011 | World Journal of Gastroenterology2011，17，10： | 16 |
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