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2篇 您的检索式:作者名="Turki Alotaibi"
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1Assessment of tear film parameters post-treatment with commercial eyelid cleaning wipes:a pilot study显示文摘AIM:To investigate the short-term effects of commercially available eyelid-cleaning wipes on film parameters.METHODS:This study enrolled 48 healthy participants aged 20-35y(both males and females).Clinical assessment included the Ocular Surface Disease Index(OSDI)questionnaire,non-invasive tear break-up time(NITBUT),tear meniscus height(TMH),and lipid layer pattern(LLP).Based on these initial results,participants were categorized as either non-dry eye or dry eye.Participants in each group were randomly allocated to either Blephaclean■or Systane■treatments.Changes in NITBUT,TMH,and LLP levels before and after lid wipe treatment were assessed.RESULTS:The dry eye group exhibited significantly higher OSDI scores and lower NITBUT and TMH levels than in the non-dry eye group(P<0.001).Following the application of eyelid wipes(Systane■wipes),dry eye subjects experienced a significant improvement in NITBUT levels(P=0.0014)compared to the non-dry eye individuals.Although the remaining participants showed a marginal increase in TMH and NITBUT levels,these changes did not achieve statistical significance(P>0.05).Similarly,the LLP levels were significantly improved with Systane■(P<0.001)post-treatment compared to individuals in the non-dry eye group.However,the dry eye subjects showed higher posttreatment LLP levels than the untreated group(P<0.02).CONCLUSION:The short-term effects of Systane®eyelid wipes on tear film parameters suggest their effectiveness in dry eye disease.Nonetheless,further exploration of their long-term impact is essential to justify their cost effectiveness and efficacy in treating both aqueous deficiency and evaporative dryness.Amal Aldarwesh Ali Almustanyir Raied Fagehi Khalaf Alruways Abdulaziz Bin Turki Mansour Alghamdi Muteb Khalaf Alanazi Balsam Alabdulkader Wafa Alotaibi Mosaad Alhassan 2024International Journal of Ophthalmology(English edition)2024,17,4:0
2Highly insulating alkane rings with destructive σ-interference显示文摘Destructive quantum interference(DQI)provides a unique approach to controlling the leakage current in the OFF state of molecular devices.However,the DQI in π-conjugated molecular building blocks cannot exhibit ultralow conductance due to the existence of covalently bonded σ-transport channels.Thus,suppressing the σ-contribution via σ-DQI is essential for the fabrication of molecular junctions with high insulation and effective modulation of conductance in single-molecule junctions.Here,we demonstrate the existence of σ-DQI even in a simple series of C_(m)C_(n) ring molecules,with parallel chains of m and n alkyl units(where m,n=6,8 or 10),by measuring their electrical conductance and Seebeck coefficients.Counterintuitively,the conductance of the symmetric C_(n)C_(n) rings is lower than that of the corresponding single chains(C_(n)),which is in contrast to the conductance superposition law in multi-channeled systems.Combined theoretical calculations reveal that the gauche conformation in a shorter chain fixed by another chain leads to the decreased conductance in alkyl rings,which originates from the phase-coherent tunneling and DQI in σ-conjugated systems.Our finding suggests that through appropriate conformation locking by cyclization,the covalent alkane system can exhibit DQI,which offers strategies for future designs of molecular electronic devices and materials.Jingyao Ye Alaa Al-Jobory Qian-Chong Zhang Wenqiang Cao Abdullah Alshehab Kai Qu Turki Alotaibi Hang Chen Junyang Liu Ali K.Ismael Zhong-Ning Chen Colin J.Lambert Wenjing Hong 2022Science China Chemistry2022,65,9:0
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