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| 1 | Clinical trial:Lactobacillus plantarum 299v(DSM 9843)improves symptoms of irritable bowel syndrome显示文摘AIM:To assess the symptomatic efficacy of Lactobacillus plantarum 299v(L.plantarum 299v)(DSM 9843) for the relief of abdominal symptoms in a large subset of irritable bowel syndrome(IBS) patients fulfilling the Rome Ⅲ criteria.METHODS:In this double blind,placebo-controlled,parallel-designed study,subjects were randomized to daily receive either one capsule of L.plantarum 299v(DSM 9843) or placebo for 4 wk.Frequency and intensity of abdominal pain,bloating and feeling of incomplete rectal emptying were assessed weekly on a visual analogue scale while stool frequency was calculated.RESULTS:Two hundred and fourteen IBS patients were recruited.After 4 wk,both pain severity(0.68 + 0.53 vs 0.92 + 0.57,P < 0.05) and daily frequency(1.01 + 0.77 vs 1.71 + 0.93,P < 0.05) were lower with L.plantarum 299v(DSM 9843) than with placebo.Similar results were obtained for bloating.At week 4,78.1 % of the patients scored the L.plantarum 299v(DSM 9843) symptomatic effect as excellent or good vs only 8.1 % for placebo(P < 0.01).CONCLUSION:A 4-wk treatment with L.plantarum 299v(DSM 9843) provided effective symptom relief,particularly of abdominal pain and bloating,in IBS patients fulfilling the Rome Ⅲ criteria. | Philippe Ducrotté Prabha Sawant Venkataraman Jayanthi | 2012 | World Journal of Gastroenterology2012，18，30： | 17 |
| 2 | Molecular mechanisms of salinity tolerance in rice显示文摘Salinity is one of the major abiotic stresses which impose constraints to plant growth and production.Rice(Oryza sativa L.)is one of the most important staple food crops and a model monocot plant.Its production is expanding into regions that are affected by soil salinity,requiring cultivars more tolerant to saline conditions.Understanding the molecular mechanisms of such tolerance could lay a foundation for varietal improvement of salt tolerance in rice.In spite of extensive studies exploring the mechanism of salt tolerance,there has been limited progress in breeding for increased salinity tolerance.In this review,we summarize the information about the major molecular mechanisms underlying salinity tolerance in rice and further discuss the limitations in breeding for salinity tolerance.We show that numerous gene families and interaction networks are involved in the regulation of rice responses to salinity,prompting a need for a comprehensive functional analysis.We also show that most studies are based on whole-plant level analyses with only a few reports focused on tissue-and/or cell-specific gene expression.More details of salt-responsive channel and transporter activities at tissue-and cell-specific level still need to be documented before these traits can be incorporated into elite rice germplasm.Thus,future studies should focus on diversity of available genetic resources and,particular,wild rice relatives,to reincorporate salinity tolerance traits lost during domestication. | Tianxiao Chen Sergey Shabala Yanan Niu Zhong-Hua Chen Lana Shabala Holger Meinke Gayatri Venkataraman Ashwani Pareek Jianlong Xu Meixue Zhou | 2021 | The Crop Journal2021，9，3： | 11 |
| 3 | Endoscopic Tri-Modal Imaging Is More Effective Than Standard Endoscopy in Identifying Early-Stage Neoplasia in Barrett’s Esophagus显示文摘 | Wouter L. Curvers Lorenza Alvarez Herrero Michael B. Wallace Louis–Michel Wong Kee Song Krish Ragunath Herbert C. Wolfsen Ganapathy A. Prasad Kenneth K. Wang Venkataraman Subramanian Bas L.A.M. Weusten Fiebo J. Ten Kate Jacques J.G.H.M. Bergman | 2010 | Gastroenterology2010，，4： | 6 |
| 4 | Clinical relevance of endoscopic assessment of inflammation in ulcerative colitis: Can endoscopic evaluation predict outcomes?显示文摘Ulcerative colitis(UC) is a chronic inflammatory bowel condition characterised by a relapsing and remitting course. Symptom control has been the traditional mainstay of medical treatment. It is well known that histological inflammatory activity persists despite adequate symptom control and absence of endoscopic inflammation. Current evidence suggests that presence of histological inflammation poses a greater risk of disease relapse and subsequent colorectal cancer risk. New endoscopic technologies hold promise for developing endoscopic markers of mucosal inflammation. Achieving endoscopic and histological remission appears be the future aim of medical treatments for UC. This review article aims to evaluate the use of endoscopy as a tool in assessment of mucosal inflammation UC and its correlation with disease outcomes. | Noor Mohammed Venkataraman Subramanian | 2016 | World Journal of Gastroenterology2016，22，42： | 6 |
| 5 | Does aspirin or non-aspirin non-steroidal anti-inflammatory drug use prevent colorectal cancer in inflammatory bowel disease?显示文摘AIM: To determine whether aspirin or non-aspirin nonsteroidal anti-inflammatory drugs(NA-NSAIDs) prevent colorectal cancer(CRC) in patients with inflammatory bowel disease(IBD).METHODS: We performed a systematic review and meta-analysis. We searched for articles reporting the risk of CRC in patients with IBD related to aspirin or NANSAID use. Pooled odds ratios(OR) and 95%CIs were determined using a random-effects model. Publication bias was assessed using Funnel plots and Egger's test. Heterogeneity was assessed using Cochran's Q and the I2 statistic.RESULTS: Eight studies involving 14917 patients and 3 studies involving 1282 patients provided data on the risk of CRC in patients with IBD taking NA-NSAIDs and aspirin respectively. The pooled OR of developing CRC after exposure to NA-NSAIDs in patients with IBD was 0.80(95%CI: 0.39-1.21) and after exposure to aspirin it was 0.66(95%CI: 0.06-1.39). There was significant heterogeneity(I2 > 50%) between the studies. There was no change in the effect estimates on subgroup a na ly s e s o f t he po pulat io n s t udie d o r w he t he r adjustment or matching was performed.CONCLUSION: There is a lack of high quality evidence on this important clinical topic. From the available evidence NA-NSAID or aspirin use does not appear to be chemopreventative for CRC in patients with IBD. | Nick E Burr Mark A Hull Venkataraman Subramanian | 2016 | World Journal of Gastroenterology2016，22，13： | 6 |
| 6 | 临床证据(14) 急性肾衰竭显示文摘背景知识 定义 急性肾衰竭(ARF)是指肾小球滤过率突然和持续性下降,导致尿素和其他化学物质在血液中堆积。目前还没有清晰一致的生化学定义,但多数研究的定义为血清肌酐(Scr)2~3mg/dL(200-250 μmol/L),在Scr基础值小于2 mg/dL(170μmol/L)时,升高0.5 mg/dL(45μmol/L) | John Kellum Martine Leblanc Ramesh Venkataraman 陈旻 | 2003 | 英国医学杂志中文版2003，6，3： | 5 |
| 7 | Impact of poly chlorinated biphenyl (Aroclor 1254) and vitamin C on antioxidant system of rat ventral prostate显示文摘Aim:To evaluate the effect of polychlorinated biphenyls (PCB) and vitamin C on ventral prostatic antioxidant system in adult male rats.Methods:A group of 20 adult male rats were administered ip Aroclor 1254 in corn oil at a dose of 2 mg.kg^-1·day^-1 for 30 days.Ten control rats were administered only the vehicle.After 30 days the treated rats were divided at random into 2 sub-groups of 10 animals each.One sub-group received vitamin C at a dose of 500 mg.kg^-1·day^-1 for 10 days.The other group was maintained as Aroclor 1254 control.Twenty-four hours after the last treatment the rats were killed by decapitation.Ventral prostatic homogenate was prepared and used for the estimation of enzymatic antioxidants,including superoxide dismutase (SOD),catalase (CAT) and glutathione-S-transferase (GST) and hydrogen peroxide (H2O2),lipid peroxidation (LPO) and prostatic acid phosphatase.The serum levels of total T3,total T4,TSH,testosterone and estradiol were also assayed.Results:The body weight and ventral prostatic weight were reduced in PCB treated rats.The activities of SOD,CAT,GST and acid phosphatase were decreased while the levels of H2O2 and lipid peroxidation were increased in the ventral prostate of PCB treated rats.Administration of vitamin C restored these parameters.Serum levels of thyroid hormones,estradiol and testosteron ewere decreased in PCB treated animals.Administration of vitamin C restored the thyroid hormone levels.Conclusion:PCB induces oxidative stress and decreases the antioxidant enzymes in the ventral prostate of adult male rats;the effects could be reversed by the administration of vitamin C.(Asian J Androl 2004 Mar;6:19-22) | M. Sridhar P. Venkataraman S. Dhanammal A. Arunkumar M.M. Aruldhas N. Srinivasan J. Arunakaran | 2004 | Asian Journal of Andrology2004，6，1： | 5 |
| 8 | International Consensus Statement on surveillance and management of dysplasia in inflammatory bowel disease显示文摘 | Loren Laine Tonya Kaltenbach Alan Barkun Kenneth R. McQuaid Venkataraman Subramanian Roy Soetikno James E. East Francis A. Farraye Brian Feagan John Ioannidis Ralf Kiesslich Michael Krier Takayuki Matsumoto Robert P. McCabe Klaus M?nkemüller Robert Odze M | 2014 | Gastrointestinal Endoscopy2014，，： | 3 |
| 9 | 碳纤维复合材料无人机叶片的仿真与分析显示文摘为得到碳纤维在无人机叶片中最优的铺层方式,通过Workbench中的ACP(ANSYS Composite PrepPost)模块,对碳纤维复合材料无人机叶片的铺层进行设计。利用SolidWorks三维建模软件建立无人机叶片的三维模型,并采用HyperMesh对叶片进行几何清理、划分网格等,利用Ansys Workbench Fluent对无人机叶片的不同转速进行流体仿真,提取叶片表面压力载荷,对不同铺层的碳纤维复合材料无人机叶片进行仿真与分析,得到碳纤维复合材料无人机叶片的力学仿真结果,并基于Tsai-Wu失效准则,计算每层铺层的失效系数,进而对比得出最优的碳纤维铺层方式为[0°,90°,90°,90°,0°]。 | 吴瑕 姚菊明 王琰 RIPON Das JIRI Militky MOHANAPRIYA Venkataraman 祝国成 | 2022 | 纺织学报2022，43，8： | 3 |
| 10 | SAR interferometric coherence analysis for snow cover mapping in the western Himalayan region显示文摘Information of snow cover(SC)over Himalayan regions is very important for regional climatological and hydrological studies.Precise monitoring of SC in the Himalayan region is essential for water supply to hydropower stations,irrigation requirements,and flood forecasting.Microwave remote sensing has all weather,day and night earth observation capability unlike optical remote sensing.In this study,spaceborne synthetic aperture radar interferometric(InSAR)coherence analysis is used to monitor SC over Himalayan rugged terrain.The feasibility of monitoring SC using synthetic aperture radar(SAR)interferometry depends on the ability to maintain coherence over InSAR pair acquisition time interval.ERS-1/2 InSAR coherence and ENVISAT ASAR InSAR coherence images are analyzed for SC mapping.Data sets of winter and of snow free months of the Himalayan region are taken for interferogram generation.Coherence images of the available data sets show maximum decorrelation in most of the area which indicates massive snowfall in the region in the winter season and melting in the summer.Area showing coherence loss due to decorrelation is mapped as a snowcovered area.The result is validated with field observations of snow depth and it is found that standing snow is inversely related to coherence in the Himalayan region. | Vijay Kumar Gopalan Venkataraman | 2011 | International Journal of Digital Earth2011，4，1： | 3 |
| 11 | Hybridization between salt resistant and salt susceptible genotypes of mungbean(Vigna radiata L.Wilczek)and purity testing of the hybrids using SSRs markers显示文摘Six cultivated and two wild genotypes of mungbean(Vigna radiata L. Wilczek) possessing variation for phenotypic and genotypic response for salt tolerance were hybridized. Hybridization results showed successful pod set and significant variations in cross-compatibility of investigated genotypes. Genotypes PLM 380 and PLM 562 showed promising combining ability with all genotypes. Results revealed significant crossing compatibility between V. radiata and V. sublobata. The cross ability ranged from 1.99 to 5.12%(average 3.08%). Molecular analysis confirmed the hybrids purity. All F_1 seeds were bold, green/shiny green and germinated between 3 to 5 days. Hybrid plants were normal, fertile and healthier over their respective progenitors. Uniform flowering and maturity of the hybrids showed absence of any defect or alteration in plant habit and life cycle of the hybrids. The hybrid plants showed increase in yield characteristics as no. of pods, pod length, 100 seeds weight, and yield per plant. Number of pods containing F_2 seeds ranged from 5–8 per cluster. The F_2 seeds were collected and stored for further research. Present study suggests that salt resistant wild relatives or cultivars of mungbean can be explored by breeding as a source of useful traits/genes providing salt tolerance. This may help in development of best mungbean variety for saline prone areas. Micro-satellite markers linked to the trait/genes may assist breeding by early selection of the genotypes compared to the phenotypic screening. | Sehrawat Nirmala Yadav Mukesh Bhat Kangila Venkataraman Sairam Raj Kumar Jaiwal Pawan Kumar | 2016 | Journal of Integrative Agriculture2016，15，3： | 3 |
| 12 | Colonic lesion characterization in inflammatory bowel disease:A systematic review and meta-analysis显示文摘AIM To perform a systematic review and meta-analysis for the diagnostic accuracy of in vivo lesion characterization in colonic inflammatory bowel disease(IBD), using optical imaging techniques, including virtual chromoendoscopy(VCE), dye-based chromoendoscopy(DBC), magnification endoscopy and confocal laser endomicroscopy(CLE). METHODS We searched Medline, Embase and the Cochrane library. We performed a bivariate meta-analysis to calculate the pooled estimate sensitivities, specificities, positive and negative likelihood ratios(+LHR,-LHR), diagnostic odds ratios(DOR), and area under the SROC curve(AUSROC) for each technology group. A subgroup analysis was performed to investigate differences in real-time nonmagnified Kudo pit patterns(with VCE and DBC) and real-time CLE.RESULTS We included 22 studies [1491 patients; 4674 polyps, of which 539(11.5%) were neoplastic]. Real-time CLE had a pooled sensitivity of 91%(95%CI: 66%-98%), specificity of 97%(95%CI: 94%-98%), and an AUSROC of 0.98(95%CI: 0.97-0.99). Magnification endoscopy had a pooled sensitivity of 90%(95%CI: 77%-96%)and specificity of 87%(95%CI: 81%-91%). VCE had a pooled sensitivity of 86%(95%CI: 62%-95%) and specificity of 87%(95%CI: 72%-95%). DBC had a pooled sensitivity of 67%(95%CI: 44%-84%) and specificity of 86%(95%CI: 72%-94%). CONCLUSION Real-time CLE is a highly accurate technology for differentiating neoplastic from non-neoplastic lesions in patients with colonic IBD. However, most CLE studies were performed by single expert users within tertiary centres, potentially confounding these results. | Richard Lord Nicholas E Burr Noor Mohammed Venkataraman Subramanian | 2018 | World Journal of Gastroenterology2018，24，10： | 2 |
| 13 | Polymer-/Ceramic-based Dielectric Composites for Energy Storage and Conversion显示文摘Dielectric composites boost the family of energy storage and conversion materials as they can take full advantage of both the matrix and filler.This review aims at summarizing the recent progress in developing highperformance polymer-and ceramic-based dielectric composites,and emphases are placed on capacitive energy storage and harvesting,solid-state cooling,temperature stability,electromechanical energy interconversion,and high-power applications.Emerging fabrication techniques of dielectric composites such as 3D printing,electrospinning,and cold sintering are addressed,following by highlighted challenges and future research opportunities.The advantages and limitations of the typical theoretical calculation methods,such as finite-element,phase-field model,and machine learning methods,for designing high-performance dielectric composites are discussed.This review is concluded by providing a brief perspective on the future development of composite dielectrics toward energy and electronic devices. | Honghui Wu Fangping Zhuo Huimin Qiao Lalitha Kodumudi Venkataraman Mupeng Zheng Shuize Wang He Huang Bo Li Xinping Mao Qiaobao Zhang | 2022 | Energy & Environmental Materials2022，5，2： | 2 |
| 14 | The Effects of Online User Reviews on Movie Box Office Performance: Accounting for Sequential Rollout and Aggregation Across Local Markets显示文摘 | Pradeep K. Chintagunta Shyam Gopinath Sriram Venkataraman | 2010 | Marketing Science2010，，5： | 2 |
| 15 | Chemoprevention of colorectal cancer in inflammatory bowel disease显示文摘 | Venkataraman Subramanian Richard F. Logan | 2011 | Best Practice & Research Clinical Gastroenterology2011，，4： | 2 |
| 16 | Biosynthesis, purification and characterization of silver nanoparticles using Escherichia coli显示文摘 | Sangiliyandi Gurunathan Kalimuthu Kalishwaralal Ramanathan Vaidyanathan Deepak Venkataraman Sureshbabu Ram Kumar Pandian Jeyaraj Muniyandi Nellaiah Hariharan Soo Hyun Eom | 2009 | Colloids and Surfaces B: Biointerfaces2009，，1： | 2 |
| 17 | Does Earnings Quality Affect Information Asymmetry? Evidence from Trading Costs*显示文摘 | Nilabhra Bhattacharya Hemang Desai Kumar Venkataraman | 2013 | Contemporary Accounting Research2013，，2： | 2 |
| 18 | The sliding wear behaviour of AlSiC particulate composites—II. The characterization of subsurface deformation and correlation with wear behaviour显示文摘 | B. Venkataraman G. Sundararajan | 1996 | Acta Materialia1996，，2： | 2 |
| 19 | Can we prevent acute kidney injury?显示文摘 | Venkataraman R | 2008 | Crit Care Med2008，36，： | 1 |
| 20 | MethiciHin-resistant staphyloeoccus aureus:comparison of susceptibility testing methods and analysis of mecA positive susceptible strains显示文摘 | Gold HS Venkataraman L | 2001 | J Clin Mierobiol2001，39，11： | 1 |
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