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| 1 | 计算机导航辅助人工全膝关节置换与常规手术的早期疗效比较显示文摘目的对比分析计算机导航辅助人工全膝关节置换与常规手术的早期疗效。方法应用三维骨建模Ceravision系统辅助人工全膝关节(Ceraver France)置换21例(男5例,女16例),对比术前、术中和术后的相关资料,分析下肢力线重建和韧带平衡的结果;检查术后3个月的膝关节活动度(ROM)与额面松弛度。对照组采用常规手术进行人工全膝关节置换20例。结果Ceravision系统对下肢力线的测量和在膝内、外翻应力下的测量均较X线片更精确。所有患者均获得人工全膝关节胫、股骨假体的满意对位和韧带平衡。术后3个月的关节活动度(ROM)平均屈曲115°;无异常的膝关节松弛度;无髌骨失稳和脱位等并发症。常规手术组的绝大部分也能获得假体的满意对位植入,术后3个月的关节活动度(ROM)平均屈曲109.4°,统计学分析显示两组的ROM比较,差异无统计学意义(P=0.06),额面松弛度比较,差异有统计学意义(P=0.03)。结论应用以三维骨建模为基础的计算机辅助手术系统,优化了人工全膝关节置换,精确地截骨和三维对位,可以更好地反映假体旋转对位情况,获得良好的膝关节屈伸位下关节间隙不衡,保证良好的膝关节韧带张力与平衡稳定,避免髌-股关节并发症,取得比常规手术更合理的额面松弛度,术后的韧带平衡稳定更好,早期疗效满意。 | 吴昊 Stéphane van Driessehe Daniel Goutallier | 2006 | 中华骨科杂志2006，26，10： | 8 |
| 2 | 三维骨建模系统在人工全膝关节置换中的优化作用:导航与常规手术早期 疗效比较(英文)显示文摘背景:人工全膝关节置换手术的重点是准确的假体三维定位,重建良好的下肢力线,维持膝关节韧带的平衡,避免髌股关节并发症,从而取得一个无痛稳定、功能良好和持久耐用的关节。目的:通过对比导航和常规全膝关节置换的近期效果,讨论三维骨建模系统对人工全膝关节置换手术中精确重建下肢力线、旋转对位和韧带平衡的优化作用。设计:分组对比观察单位:法国亨利蒙多医院矫形与创伤外科。对象:选2002-11/2003-06 在法国亨利蒙多医院矫形与创伤外科进行的计算机辅助人工膝关节置换21例为导航手术组,年龄64~79 岁,14 例膝内翻,7例膝外翻;常规手术人工膝关节置换20例传统手术组,年龄 65~83 岁,15例膝内翻,5例膝外翻;纳入标准均为的骨性关节炎患者,排除复治的人工全膝关节翻修术患者,患者均知情同意。方法:均采用后稳定型人工表面全膝关节(Hermes?法国 Ceraver),两组的手术基本操作相同,导航手术组在 Ceravision ?无需影像资料的三维骨建模(Bone-Morphing)计算机辅助系统监控下进行。主要观察指标:对比术前、术中和术后的相关影像资料,分析下肢力线重建和韧带平衡的结果;检查术后 3 个月手术膝关节的活动度、额面松弛度和髌骨稳定性。结果:41例患者均进入结果分析。①所有患者都获得人工膝关节胫、股骨假体的满意对位植入和韧带平衡。②Ceravision系统对下肢力线的测量及在膝内外翻应力下的测量均比X射线片更精确;两组病例的下肢力线都在内外翻3°的范围内(P> 0.05)。③两组术后3个月的关节活动度比较差异不显著(P=0.06);导航手术组膝关节额面松弛度优于常规手术组(P=0.03)。④两组均无髌骨失稳和脱位等并发症。结论:应用以三维骨建模为基础的计算机辅助手术系统,优化了人工全膝关节置换,精确实现了截骨和三维对位,获得良好的膝关节屈伸位下关节等距间隙,保证良好的膝关节韧带张力与平衡稳定,取得比常规手术更合理的额面松弛度,术后的韧带平衡稳定更好,早期疗效满意。 | 吴昊 Stéphane Van Driessche Daniel Goutallier | 2008 | 中国组织工程研究与临床康复2008，12，13： | 6 |
| 3 | 安捷伦液相/离子阱(XCT)质谱检测虾仁及家禽中的硝基呋喃代谢物显示文摘在液相/离子阱质谱上,利用液相/质谱/质谱方法对鸡肉及虾仁中硝基呋喃代谢物残留进行了定性定量分析.对于四种硝基呋喃代谢物,其定量限在0125到05μg·kg-1的范围内,分析结果完全满足欧盟的1μg·kg-1的最低检测限量的要求. | Bernhard wüst Christian Sauber Hans (J) A van Rhijn | 2004 | 环境化学2004，23，6： | 2 |
| 4 | Postoperative complications and weight loss following jejunostomy tube feeding after total gastrectomy for advanced adenocarcinomas显示文摘Objective: Patients undergoing total gastrectomy for cancer are at risk of malnourishment. The aim of this selfcontrolled study was to examine the effect of jejunostomy tube feeding(JTF) and other factors on postoperative weight and the incidence of jejunostomy-related complications in patients undergoing total gastrectomy for cancer.Methods: All consecutive patients who underwent total gastrectomy for gastric cancer with jejunostomy placement were included from a prospective single-center database(2003–2014). Jejunostomy-related complications and postoperative weight changes were evaluated up to 12 months after surgery. Multivariable linear regression analysis was performed to identify factors associated with weight loss 12 months after gastrectomy.Results: Of 113 patients operated in the study period, 65 received JTF after total gastrectomy for a median duration of 18 d [interquartile range(IQR), 10–55 d]. Jejunostomy-related complications occurred in 11(17%)patients, including skin leakage(n=3) and peritoneal leakage(n=2), luxation(n=3), occlusion(n=2), infection(n=1)and torsion(n=1). In 2(3%) patients, a reoperation was needed due to jejunostomy-related complications. The mean preoperative weight of patients was 71.8 kg(100%), and remained stable during JTF(73.9 kg, 103%,P=0.331). After JTF was stopped, the mean weight of patients decreased to 64.9 kg(90%) at 12 months after surgery(P<0.001). A high preoperative body mass index(BMI)(≥25 kg/m^2) was associated with high postoperative weight loss compared to patients with a low BMI(<25 kg/m^2)(16.3% vs. 8.6%, P=0.016).Conclusions: JTF can prevent weight loss in the early postoperative phase. However, this is at the prize of possible complications. As weight loss in the long term is not prevented, routine JTF should be re-evaluated and balanced against the selected use in preoperatively malnourished patients. Special attention should be paid to patients with a high preoperative BMI, who are at risk of more postoperative weight loss. | hylke j.f.brenkman stéphanie v.s.roelen elles steenhagen jelle p.ruurda richard van hillegersberg | 2017 | Chinese Journal of Cancer Research2017，29，4： | 2 |
| 5 | 计算机辅助下相关数字影像资料对人工全膝关节置换术的优化作用显示文摘目的:基于Ceravision系统辅助人工全膝关节置换的手术结果,讨论相关数字影像资料对优化人工全膝关节置换术的作用。方法:选择2002-11/2003-06法国亨利蒙多医院(HOPITALHENRIMONDOR)矫形与创伤外科用三维骨建模Ceravision导航系统辅助完成的21例人工全膝关节置换术患者的影像资料进行对比分析,根据术前的常规膝关节X射线片,下肢全长片、全麻下膝关节内外翻应力X射线片和髋、膝、踝扭转的CT片,以及术中Ceravision系统检测和术后X射线片,效果评估以重建的下肢力线膝关节内外翻≤3°为满意。①术前和术中膝关节内、外翻角度。②应力下术前和术中膝关节内、外翻角度。③术毕膝关节内、外翻角度。④并发症。结果:按意向处理分析,21例患者均进入结果分析。①下肢力线测量结果:术前X射线下肢全长片与术中电脑导航系统的测量平均外翻2.36°(内翻13°~外翻13°),3.33°(内翻12°~外翻10°),二者比较有显著差异(P=0.0025)。②应力下膝内翻、外翻测量结果:术前X射线正位片测量与术中导航系统的测量平均8.47°(内翻2°~内翻20°),3.63°(内翻7°~外翻12°),6.47°(内翻0°~内翻24°),4.32°(内翻8°~外翻15°),二者比较有显著差异(P<0.0001)。③术毕时膝内外翻测量结果:导航系统测得的膝内外翻平均为0.175°(内翻2°~外翻3°),术后X射线下肢全长片测量平均0.3°(内翻3.5°~外翻1.5°),二者比较,无明显差别(P>0.05)。④不良事件和副反应:所有的膝关节胫、股骨部件都得到满意的摆位置入。无髌骨失稳和脱位等并发症,且无异常的关节松弛度。结论:Ceravision系统辅助全膝人工关节置换术,有利于术中人机互动,取得精确的假体定位及韧带平衡和准确置换,达到下肢力线在内外翻3°以内范围的满意效果。 | 吴昊 邱维加 Van Driessche Stéphane Goutallier Daniel | 2005 | 中国临床康复2005，9，22： | 2 |
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