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| 1 | Clinical outcomes of self-expandable stent placement for benign esophageal diseases: A pooled analysis of the literature显示文摘AIM: To analyze the outcomes of self-expandable stent placement for benign esophageal strictures and benign esophageal leaks in the literature.METHODS: The Pub Med, Embase and Cochrane databases were searched for relevant articles published between January 2000 and July 2014. Eight prospective studies were identified that analyzed the outcomes of stent placement for refractory benign esophageal strictures. The outcomes of stent placement for benign esophageal leaks, perforations and fistulae were extracted from 20 retrospective studies that were published after the inclusion period of a recent systematic review. Data were pooled and analyzed using descriptive statistics.RESULTS: Fully covered self-expandable metal stents(FC SEMS)(n = 85), biodegradable(BD) stents(n = 77) and self-expandable plastic stents(SEPS)(n = 70) were inserted in 232 patients with refractory benign esophageal strictures. The overall clinical success rate was 24.2% and according to stent type 14.1% for FC SEMS, 32.9% for BD stents and 27.1% for SEPS. Stent migration occurred in 24.6% of cases. The overall complication rate was 31.0%, including major(17.7%) and minor(13.4%) complications. A total of 643 patients were treated with self-expandable stents mainly for postsurgical leaks(64.5%), iatrogenic perforations(19.6%), Boerhaave's syndrome(7.8%) and fistulae(3.7%). FC SEMS and partially covered SEMS were used in the majority of patients. Successful closure of the defect was achieved in 76.8% of patients and according to etiology in 81.4% for postsurgical leaks, 86.0% for perforations and 64.7% for fistulae. The pooled stent migration rate was 16.5%. Stent-related complications occurred in 13.4% of patients, including major(7.8%) and minor(5.5%) complications.CONCLUSION: The outcomes of stent placement for refractory benign esophageal strictures were poor. However, randomized trials are needed to put this into perspective. The evidence on successful stent placement for benign esophageal leaks, perforationsand fistulae is promising. | Emo E van Halsema Jeanin E van Hooft | 2015 | World Journal of Gastrointestinal Endoscopy2015，7，2： | 10 |
| 2 | Endoscopic ultrasonography-guided fine needle aspiration:Relatively low sensitivity in the endosonographer population显示文摘AIM:To assess the characteristics and quality of endoscopic ultrasonography-guided fine needle aspiration(EUS-FNA) in a large panel of endosonographers.METHODS:A survey was conducted during the 13th annual live course of endoscopic ultrasonography(EUS) held in Amsterdam,Netherlands.A 2-page questionnaire was developed for the study.Content validity of the questionnaire was determined based on input by experts in the field and a review of the relevant literature.It contained 30 questions that pertained to demographics and the current practice for EUS-FNA of responders,including sampling technique,sample processing,cytopathological diagnosis and sensitivity of EUS-FNA for the diagnosis of solid mass lesions.One hundred and sixty-one endosonographers who attended the course were asked to answer the survey.This allowed assessing the current practice of EUS-FNA as well as the self-reported sensitivity of EUS-FNA for the diagnosis of solid mass lesions.We also examined which factors were associated with a self-reported sensitivity of EUS-FNA for the diagnosis of solid mass lesions > 80%.RESULTS:Completed surveys were collected from 92(57.1%) of 161 endosonographers who attended the conference.The endosonographers had been practicing endoscopy and EUS for 12.5 ± 7.8 years and 4.8 ± 4.1 years,respectively;one third of them worked in a hospital with an annual caseload > 100 EUS-FNA.Endoscopy practices were located in 29 countries,including 13 countries in Western Europe that totaled 75.3% of the responses.Only one third of endosonographers reported a sensitivity for the diagnosis of solid mass lesions > 80%(interquartile range of sensitivities,25.0%-75.0%).Factors independently associated with a sensitivity > 80% were(1) > 7 needle passes for pancreatic lesions or rapid on-site cytopathological evaluation(ROSE)(P < 0.0001),(2) a high annual hospital caseload(P = 0.024) and(3) routine isolation of microcores from EUS-FNA samples(P = 0.042).ROSE was routinely available to 27.9% of respondents.For lymph nodes and pancreatic masses,a maximum of three needle passes was performed by approximately two thirds of those who did not have ROSE.Microcores were routinely harvested from EUS-FNA samples by approximately one third(37.2%) of survey respondents.CONCLUSION:EUS-FNA sensitivity was considerably lower than reported in the literature.Low EUS-FNA sensitivity was associated with unavailability of ROSE,few needle passes,absence of microcore isolation and low hospital caseload. | Jean-Marc Dumonceau Thibaud Koessler Jeanin E van Hooft Paul Fockens | 2012 | World Journal of Gastroenterology2012，18，19： | 7 |
| 3 | Plasma microRNA profiles distinguish lethal injury in acetaminophen toxicity: A research study显示文摘AIM: To investigate plasma microRNA (miRNA) profiles indicative of hepatotoxicity in the setting of lethal acetaminophen (APAP) toxicity in mice. METHODS: Using plasma from APAP poisoned mice, either lethally (500 mg/kg) or sublethally (150 mg/kg) dosed, we screened commercially available murine microRNA libraries (SABiosciences, Qiagen Sciences, MD) to evaluate for unique miRNA profiles between these two dosing parameters. RESULTS: We distinguished numerous, unique plasma miRNAs both up- and downregulated in lethally compared to sublethally dosed mice. Of note, many of the greatest up- and downregulated miRNAs, namely 574-5p, 466g, 466f-3p, 375, 29c, and 148a, have been shown to be associated with asthma in prior studies. Interestingly, a relationship between APAP and asthma has been previously well described in the literature, with an as yet unknown mechanism of pathology. There was a statistically significant increase in alanine aminotransferase levels in the lethal compared to sublethal APAP dosing groups at the 12 h time point (P < 0.001). There was 90% mortality in the lethally compared to sublethally dosed mice at the 48 h time point (P = 0.011). CONCLUSION: We identified unique plasma miRNAs both up- and downregulated in APAP poisoning which are correlated to asthma development. | Jeanine Ward Shashi Bala Jan Petrasek Gyongyi Szabo | 2012 | World Journal of Gastroenterology2012，18，22： | 6 |
| 4 | 特发性少精子症和无精子症与Pygo2基因蛋白编码区SNPs的相关性显示文摘男性不育常伴随精子数量减少。Pygo2基因在染色质重塑的伸长精细胞中表达,其功能受损会导致精子形成阻滞和精子生成减少而引发不育。文章旨在检测引起人特发性少精子症和无精子症的Pygo2基因突变。从77例正常生育力男性和195例特发性少精子症和无精子症患者静脉血提取DNA,采用聚合酶链式反应-测序方法对Pygo2基因3个蛋白质编码区进行测序对比,非同义单核苷酸多态性(Single nucleotide polymorphisms,SNPs)位点分别用SIFT、Polyphen-2和Mutation Taster软件进行诱发蛋白质结构和表型改变的检测和分析。结果表明,195例患者中,178例(30例轻度或中度少精子症,57例重度少精子症和91例无精子症)基因序列分析报告完好,无精子症中3例患者分别在2个位点(rs61758740,rs141722381)发生了非同义突变SNPs,重度少精子症中1例患者在位点rs61758741发生了非同义突变,3个突变位点在SNPs基因数据库都已有报道,轻度或中度少精子症患者以及正常生育力男性中不存在SNPs。rs61758740可使PYGO2蛋白第141位蛋氨酸(M)变为异亮氨酸(I),rs61758741使PYGO2蛋白第261位碱性赖氨酸(K)变为酸性谷氨酸(E),rs141722381使PYGO2蛋白第240位亲水侧链天冬酰胺(N)变为疏水侧链异亮氨酸(I)。软件分析表明,在所发现的3个SNP非同义突变位点中,rs141722381引起的单个氨基酸改变会导致PYGO2蛋白空间结构破坏和诱发相关疾病。因此,Pygo2基因蛋白质编码序列区SNPs可能是特发性少精子症和无精子症的诱发因素之一,导致男性不育。 | 葛少钦 Jeanine Grifin 刘丽华 Kenneth I.Aston Luke Simon Timothy G.Jenkins Benjamin R.Emery Douglas T.Carrell | 2013 | 遗传2013，35，5： | 6 |
| 5 | Artificial intelligence in gastroenterology: A state-of-the-art review显示文摘The development of artificial intelligence(AI)has increased dramatically in the last 20 years,with clinical applications progressively being explored for most of the medical specialties.The field of gastroenterology and hepatology,substantially reliant on vast amounts of imaging studies,is not an exception.The clinical applications of AI systems in this field include the identification of premalignant or malignant lesions(e.g.,identification of dysplasia or esophageal adenocarcinoma in Barrett’s esophagus,pancreatic malignancies),detection of lesions(e.g.,polyp identification and classification,small-bowel bleeding lesion on capsule endoscopy,pancreatic cystic lesions),development of objective scoring systems for risk stratification,predicting disease prognosis or treatment response[e.g.,determining survival in patients post-resection of hepatocellular carcinoma),determining which patients with inflammatory bowel disease(IBD)will benefit from biologic therapy],or evaluation of metrics such as bowel preparation score or quality of endoscopic examination.The objective of this comprehensive review is to analyze the available AI-related studies pertaining to the entirety of the gastrointestinal tract,including the upper,middle and lower tracts;IBD;the hepatobiliary system;and the pancreas,discussing the findings and clinical applications,as well as outlining the current limitations and future directions in this field. | Paul T Kröner Megan ML Engels Benjamin S Glicksberg Kipp W Johnson Obaie Mzaik Jeanin E van Hooft Michael B Wallace Hashem B El-Serag Chayakrit Krittanawong | 2021 | World Journal of Gastroenterology2021，27，40： | 6 |
| 6 | Self-expandable metal stents for malignant gastric outlet obstruction: A pooled analysis of prospective literature显示文摘AIM: To provide an overview of the clinical outcomes of self-expandable metal stent(SEMS) placement for malignant gastric outlet obstruction(MGOO).METHODS: A systematic literature search was performed in Pub Med of the literature published between January 2009 and March 2015. Only prospective studies that reported on the clinical success of stent placement for MGOO were included. The primary endpoint was clinical success,defined according to the definition used in the original article. Data were pooled and analyzed using descriptive statistics. Subgroup analyses were performed for partially covered SEMSs(PCSEMSs) and uncovered SEMSs(UCSEMSs) using Fisher's exact test.RESULTS: A total of 19 studies,including 1281 patients,were included in the final analysis. Gastric(42%) and pancreatic(37%) cancer were the main causes of MGOO. UCSEMSs were used in 76% of patients and PCSEMSs in 24%. The overall pooled technical success rate was 97.3% and the clinical success rate was 85.7%. Stent dysfunction occurred in 19.6% of patients,mainly caused by re-obstruction(12.6%) and stent migration(4.3%),and was comparable between PCSEMSs and UCSEMSs(21.2% vs 19.1%,respectively,P = 0.412). Re-obstruction was more common with UCSEMSs(14.9% vs 5.1%,P < 0.001) and stent migration was more frequent after PCSEMS placement(10.9% vs 2.2%,P < 0.001). The overall perforation rate was 1.2%. Bleeding was reported in 4.1% of patients,including major bleeding in 0.8%. The median stent patency ranged from 68 to 307 d in five studies. The median overall survival ranged from 49 to 183 d in 13 studies.CONCLUSION: The clinical outcomes in this large population showed that enteral stent placement was feasible,effective and safe. Therefore,stent placement is a valid treatment option for the palliation of MGOO. | Emo E van Halsema Erik AJ Rauws Paul Fockens Jeanin E van Hooft | 2015 | World Journal of Gastroenterology2015，21，43： | 5 |
| 7 | Pancreatitis and pancreatic cancer:A case of the chicken or the egg显示文摘Acute pancreatitis(AP),chronic pancreatitis(CP)and pancreatic cancer are three distinct pancreatic diseases with different prognoses and treatment options.However,it may be difficult to differentiate between benign and malignant disease.AP may be a first symptom of pancreatic cancer,particularly in patients between the ages of 56 and 75 with presumed idiopathic AP who had a concomitant diagnosis of new-onset diabetes mellitus or patients who present with CP at diagnosis of AP.In these patients,additional imaging is warranted,preferably by endoscopic ultrasonography.CP may lead to pancreatic cancer through oncogenic mutations,mostly in patients with hereditary CP,and in patients in whom risk factors for pancreatic cancer(e.g.,nicotine and alcohol abuse)are also present.Patients with PRSS1-mediated CP and patients with a history of autosomal dominant hereditary CP without known genetic mutations may be considered for surveillance for pancreatic cancer.Pancreatic inflammation may mimic pancreatic cancer by appearing as a focal mass-forming lesion on imaging.Differentiation between the above mentioned benign and malignant disease may be facilitated by specific features like the duct-penetrating sign and the duct-to-parenchyma ratio.Research efforts are aimed towards developing a superior discriminant between pancreatitis and pancreatic cancer in the form of imaging modalities or biomarkers.This may aid clinicians in timely diagnosing pancreatic cancer in a potentially curable stage. | Devica S Umans Sanne A Hoogenboom Noor J Sissingh Selma J Lekkerkerker Robert C Verdonk Jeanin E van Hooft | 2021 | World Journal of Gastroenterology2021，27，23： | 5 |
| 8 | 哈萨克斯坦北部小麦遥感估产方法研究显示文摘以哈萨克斯坦北部雨养耕作区为研究靶区,基于春小麦产量统计数据和遥感光谱指数,开展了春小麦估产最优预测时期及植被指数分析,采用回归分析、随机森林、支持向量机及双向循环神经网络模型估算春小麦产量,并对比分析了不同模型的模拟精度。结果表明:北哈萨克斯坦州、阿克莫拉州和库斯塔纳州2007-2016年春小麦估产的最佳预测时期为6月26日-8月5日,该时期是春小麦产量形成的关键时期。北哈萨克斯坦州春小麦估产最优植被指数为7月12日的绿度叶绿素指数(Green chlorophyll index,CI_(green)),阿克莫拉州春小麦估产最优植被指数为8月5日的绿度动态宽波段指数(Green wide dynamic range vegetation index,WDRVI_(green)),库斯塔纳州春小麦最优估产植被指数为7月12日的WDRVI_(green)。对比分析4种模型模拟春小麦产量的精度,在样本点较少的情况下,双向循环神经网络模型相比其他模型在估算哈萨克斯坦北部三州春小麦产量上精度较高;春小麦产量与植被净初级生产力NPP相关性分析结果显示,北哈萨克斯坦州、阿克莫拉州和库斯塔纳州决定系数R2在0.50以上面积占比分别为44%、94%和77%,表明上述估产模型可应用于哈萨克斯坦北部三州春小麦估产,尤其是阿克莫拉州和库斯塔纳州。 | 尹瀚民 古丽·加帕尔 于涛 Jeanine UMUHOZA 李旭 | 2022 | 干旱区地理2022，45，2： | 4 |
| 9 | Colonic stenting versus emergency surgery for acute left-sided malignant colonic obstruction: a multicentre randomised trial显示文摘 | Jeanin E van Hooft Willem A Bemelman Bas Oldenburg Andreas W Marinelli Martijn F Lutke Holzik Marina J Grubben Mirjam A Sprangers Marcel G Dijkgraaf Paul Fockens | 2011 | Lancet Oncology2011，，4： | 3 |
| 10 | Efficacy and safety of the new WallFlex enteral stent in palliative treatment of malignant gastric outlet obstruction (DUOFLEX study): a prospective multicenter study显示文摘 | Jeanin E. van Hooft Madeleen J. Uitdehaag Marco J. Bruno Robin Timmer Peter D. Siersema Marcel G.W. Dijkgraaf Paul Fockens | 2009 | Gastrointestinal Endoscopy2009，，6： | 2 |
| 11 | Visit‐to‐Visit Blood Pressure Variability and Cardiovascular Death in the Systolic Hypertension in the Elderly Program显示文摘 | John B. Kostis Jeanine E. Sedjro Javier Cabrera Nora M. Cosgrove John S. Pantazopoulos William J. Kostis Sara L. Pressel Barry R. Davis | 2014 | J Clin Hypertens2014，，1： | 2 |
| 12 | Novel UBE2B-associated polymorphisms in an azoospermic / oligozoospermic population显示文摘瞄准:估计畸形是否在不肥沃的人的男性的一张人口在 UBE2B 基因存在,并且建立任何发现变化的生物学的似有道理。方法:我们执行了聚合酶链反应(PCR ) 5'-untranslated 区域的扩大和顺序分析和 UBE2B 基因的六前 ons 包括 flanking intronic 区域,在一组肥沃、不肥沃的人。跟随在一个 10-CGG 重复岛以内包含了单个或双的三位字节删除的一个通常认为的倡导者区域的鉴定,我们用 DNA 蛋白质胶化移动试金作为与野类型的顺序相比评估了这些识别多型性的有约束力的亲密关系到抄写因素 SP1。结果:有新奇 exonic 单身者核苷酸多型性(SNP ) ,在 5% 不肥沃的人在 4 上在前注意。在 silico 3D,改变的蛋白质当模特儿为缬氨酸替换显示出无害的异白氨酸。没有变化,在任何另外的前 ons 以内注意。三新奇 intronic SNP 在肥沃的组,和在不肥沃的组识别的七新奇 intronic SNP 以内被识别。DNA 蛋白质胶化移动试金注意两个挑选 CGG 删除和近似有两次的两倍 CGG 删除乐队有约束力的亲密关系与相比为 SP1 野类型。否定控制没证实非特定的蛋白质绑定。结论:自己,单个或双的 CGG 删除是不大可能的提出生物学的意义。然而,在这个怀疑的倡导者区域的如此的删除为 SP1 与增加的有约束力的亲密关系被联系,并且可能代表为 UBE2B 基因表示的改变要求的几个因素之一。 | Ivan Huang Benjamin R. Emery Greg L. Christensen Jeanine Griffin C. Matthew Peterson Douglas T. Carrell | 2008 | Asian Journal of Andrology2008，10，3： | 2 |
| 13 | Twin Anemia Polycythemia Sequence: Knowledge and Insights After 15 Years of Research显示文摘Twin anemia polycythemia sequence (TAPS) is a chronic form of unbalanced feto-fetal transfusion through minuscule placental anastomoses in monochorionic twin pregnancies, leading to anemia in the donor twin and polycythemia in the recipient twin. TAPS can occur spontaneously in up to 5% of monochorionic twins or can arise in 2%-16% of cases after incomplete laser surgery for twin-twin transfusion syndrome. TAPS can develop across the entire second and third trimester. Antenatal diagnosis for TAPS is reached via Doppler measurement of the fetal middle cerebral artery peak systolic velocity, showing an increased velocity in the donor, combined with a decreased velocity in the recipient. Treatment options for TAPS include expectant management, preterm delivery, intrauterine blood transfusion with or without a partial exchange transfusion, fetoscopic laser surgery and selective feticide. The best treatment option is unclear and is currently being investigated in an international multicenter randomized trial (the TAPS trial). Spontaneous fetal demise occurs in 5%-11% of TAPS twins, more often in donors (8%-18%) than in recipients (2%-5%). Severe long-term neurodevelopmental impairment is seen in 9% of TAPS twins, with donors having an increased risk for cognitive impairment and hearing problems (15%). | Lisanne S.A.Tollenaar Enrico Lopriore Dick Oepkes Monique C.Haak Frans J.C.M.Klumper Johanna M.Middeldorp Jeanine M.M.Van Klink Femke Slaghekke | 2021 | Maternal-Fetal Medicine2021，3，1： | 2 |
| 14 | EUS-guided fiducial markers placement with a 22-gauge needle for image-guided radiation therapy in pancreatic cancer显示文摘 | Raquel Dávila Fajardo Selma J. Lekkerkerker Astrid van der Horst Eelco Lens Jacques J. Bergman Paul Fockens Arjan Bel Jeanin E. van Hooft | 2013 | Gastrointestinal Endoscopy2013，，： | 2 |
| 15 | Polyacrylamide as an organic nitrogen source for soil microorganisms with potential effects on inorganic soil nitrogen in agricultural soil 显示文摘 | Jeanine L K Mary E W Rodrick D L | 1998 | Soil Biology & Biochemistry1998，30，8： | 1 |
| 16 | Effect of ozone on disinfection by-product formation of algae显示文摘 | Jeanine Plammer D | 1998 | Water Scl Tech1998，37，2： | 1 |
| 17 | Amatoxin Poisoning: Case Reports and Review of Current Therapies显示文摘 | Jeanine Ward Kishan Kapadia Eric Brush Steven D. Salhanick | 2012 | Journal of Emergency Medicine2012，，： | 1 |
| 18 | Polyacrylamide as an organic nitrogen source for soil microorganisms with potential effects on inorganic soil nitrogen in agricultural soil显示文摘 | Jeanine L Kay-Shoemake Mary E Watwood Rodriek D Lentz | 1998 | Soil Biology & Biochemistry1998，30，89： | 1 |
| 19 | Determination of chlorine dioxide in concentrated solutions in the presence of chlorine显示文摘 | Marcel Lepeintre Jeanine D Jean O 1960 | 1960 | Chim Anal1960，42，： | 1 |
| 20 | Steanl trap test methods cat cost and save energy显示文摘 | FRENCH SCOTT A KATZEL JEANINE | 1998 | Plant Engineering1998，52，10： | 1 |
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