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| 1 | NKT cell subsets as key participants in liver physiology and pathology显示文摘自然漂亮 T (NKT ) 房间是通常认出类脂化合物抗原的象天生一样淋巴细胞并且在肝的 microvascular 分隔空间被充实。NKT 房间能被自我类脂化合物或微生物引起类脂化合物的抗原并且由通过像使用费的受体发信号激活。后面的激活, NKT 房间很快分泌支持 inflammatory 或反煽动性的 cytokines 和 chemokines,并且从而为随后的免疫或忍耐决定周围。这正在变得清楚 NKT cells— 的二个不同子集;类型我和类型 II—有抗原识别的不同模式并且让在煽动性的肝疾病反对角色。这里,我们在肝主要集中于两个 NKT 房间子集的角色在有免疫力的忍耐和煽动性的疾病的维护。而且,怎么我和类型 II NKT 房间影响的类型的微分激活到在为织物正直的重要后果的结果的另外的天生的房间和适应有免疫力的房间被讨论。包括 CD1d tetramers,更好的试剂在临床的研究被使用在病人在肝疾病定义 NKT 房间的角色,是关键的。 | Keya Bandyopadhyay Idania Marrero Vipin Kumar | 2016 | Cellular & Molecular Immunology2016，13，3： | 23 |
| 2 | Implant biomaterials: A comprehensive review显示文摘Appropriate selection of the implant biomaterial is a key factor for long term success of implants. The biologic environment does not accept completely any material so to optimize biologic performance, implants should be selected to reduce the negative biologic response while maintaining adequate function. Every clinician should always gain a thorough knowledge about thedifferent biomaterials used for the dental implants. This article makes an effort to summarize various dental biomaterials which were used in the past and as well as the latest material used now. | Monika Saini Yashpal Singh Pooja Arora Vipin Arora Krati Jain | 2015 | World Journal of Clinical Cases2015，3，1： | 15 |
| 3 | Invariant natural killer T cells contribute to chronic-plus-binge ethanol-mediated liver injury by promoting hepatic neutrophil infiltration显示文摘嗜中性的渗入是含酒精的 steatohepatitis 的一个特点;然而,内在的机制仍然保持不清楚。我们以前报导 synergistically 喂的 chronic-plus-binge 乙醇导致 neutrophils 的肝的招募,它贡献肝损害。在这份报纸,我们在 chronic-plus-binge 乙醇喂导致调查了不变的自然漂亮 T (iNKT ) 房间的角色肝的嗜中性的渗入和肝损害。野类型并且 iNKT 的二紧张房间缺乏的老鼠(CD1d 缺乏并且 Jα 18-deficient 老鼠) 受到喂的 chronic-plus-binge 乙醇。肝损害和发炎被检验。synergistically 喂的 Chronic-plus-binge 乙醇增加了肝的 iNKT 房间的数字并且导致了他们的激活,与独自的长期的喂或饮酒作乐相比。iNKT 房间缺乏的老鼠被保护免受 chronic-plus-binge 的伤害导致乙醇的肝的嗜中性的渗入和肝损害。而且,显著地喂几基因的肝的表示在野类型的老鼠与发炎和嗜中性的招募联系了的 upregulated 的 chronic-plus-binge 乙醇,而是这些基因的正式就职在 iNKT 被废除房间缺乏的老鼠。重要地,几 cytokines 和 chemokines (例如, MIP-2, MIP-1, IL-4, IL-6 和 osteopontin ) 在嗜中性的渗入包含了在肝的 NKT 房间的 upregulated 从 chronic-plus-binge 被孤立与喂对的老鼠相比的喂乙醇的老鼠。最后,有堵住抗体的 CD1d 的处理,堵住 iNKT 房间激活,部分阻止了 chronic-plus-binge 导致乙醇的肝损害和发炎。喂的 Chronic-plus-binge 乙醇激活肝的 iNKT 房间,它在早含酒精的肝损害的发展起一个关键作用,部分地由释放招募的调停人 neutrophils 到肝,并且这样, iNKT 房间为含酒精的肝的治疗代表一个潜在的治疗学的目标疾病。 | Stephanie Mathews Dechun Feng Igor Maricic Cynthia Ju Vipin Kumar Bin Gao | 2016 | Cellular & Molecular Immunology2016，13，2： | 14 |
| 4 | Development of metal organic fromwork-199 immobilized zeolite foam for adsorption of common indoor VOCs显示文摘Reticulated foam shaped adsorbents are more efficient for the removal of volatile organic compounds(VOCs),particularly from low VOC-concentration indoor air streams. In this study composite structure of zeolite and metal organic frameworks(MOFs),referred as ZMF,has been fabricated by immobilization of fine MOF-199 powder on foam shaped Zeolite Socony Mobil-5(ZSM-5)Zeolitic structure,referred as ZF. The ZMF possess a uniform and well-dispersed coating of MOF-199 on the porous framework of ZF. It shows higher surface area,pore volume,and VOCs adsorption capacity,as compared to ZF-structure.Post-fabrication changes in selective adsorption properties of ZMF were studied with three common indoor VOCs(benzene,n-hexane,and cyclohexane),using gravimetric adsorption technique. The adsorption capacity of ZMF with different VOCs follow the order of benzene > n-hexane > cyclohexane. In comparison with MOF-199 and ZF,the composite structure ZMF shows improvement in selectivity for benzene from other two VOCs. Further,improvement in efficiency and stability of prepared ZMF was found to be associated with its high MOF loading capacity and unique morphological and structural properties. The developed composite structure with improved VOCs removal and recyclability could be a promising material for small to limited scale air pollution treatment units. | Vipin K.Saini Joao Pires | 2017 | Journal of Environmental Sciences2017，29，5： | 14 |
| 5 | Pancreatic injury in patients with septic shock: A literature review显示文摘Sepsis and septic shock are life threatening condition associated with high mortality rate in critically-ill patients. This high mortality is mainly related to the inadequacy between oxygen delivery and cellular demand leading to the onset of multiorgan dysfunction. Whether this multiorgan failure affect the pancreas is not fully investigated. In fact, pancreatic injury may occur because of ischemia, overwhelming inflammatory response, oxidative stress, cellular apoptosis and/or metabolic derangement. Increased serum amylase and/or lipase levels are common in patients with septic shock. However, imaging test rarely reveal significant pancreatic damage. Whether pancreatic dysfunction does affect the prognosis of patients with septic shock or not is still a matter of debate. In fact, only few studies with limited sample size assessed the clinical relevance of the pancreatic injury in this group of patients. In this review, we aimed to describe the epidemiology and the physiopathology of pancreatic injury in septic shock patients, to clarify whether it requires specific management and to assess its prognostic value. Our main finding is that pancreatic injury does not significantly affect the outcome in septic shock patients. Hence, increased serum pancreatic enzymes without clinical features of acute pancreatitis do not require further imaging investigations and specific therapeutic intervention. | Anis Chaari Karim Abdel Hakim Kamel Bousselmi Mahmoud Etman Mohamed El Bahr Ahmed El Saka Eman Hamza Mohamed Ismail Elsayed Mahmoud Khalil Vipin Kauts William Francis Casey | 2016 | World Journal of Gastrointestinal Oncology2016，8，7： | 8 |
| 6 | Role of gut microbiota in cardiovascular diseases显示文摘The human gut is colonized by a community of microbiota,primarily bacteria,that exist in a symbiotic relationship with the host.Intestinal microbiota-host interactions play a critical role in the regulation of human physiology.Deleterious changes to the composition of gut microbiota,referred to as gut dysbiosis,has been linked to the development and progression of numerous diseases,including cardiovascular disease(CVD).Imbalances in host-microbial interaction impair homeostatic mechanisms that regulate health and can activate multiple pathways leading to CVD risk factor progression.Most CVD risk factors,including aging,obesity,dietary patterns,and a sedentary lifestyle,have been shown to induce gut dysbiosis.Dysbiosis is associated with intestinal inflammation and reduced integrity of the gut barrier,which in turn increases circulating levels of bacterial structural components and microbial metabolites,including trimethylamine-N-oxide and short-chain fatty acids,that may facilitate the development of CVD.This article reviews the normal function and composition of the gut microbiome,mechanisms leading to the leaky gut syndrome,its mechanistic link to CVD and potential novel therapeutic approaches aimed towards restoring gut microbiome and CVD prevention.As CVD is the leading cause of deaths globally,investigating the gut microbiota as a locus of intervention presents a novel and clinically relevant avenue for future research. | Marko Novakovic Amit Rout Thomas Kingsley Robert Kirchoff Amteshwar Singh Vipin Verma Ravi Kant Rahul Chaudhary | 2020 | World Journal of Cardiology2020，12，4： | 6 |
| 7 | Specific Control of Immunity by Regulatory CD8 T Cells显示文摘T lymphocytes with dedicated suppressor function (Treg) play a crucial role in the homeostatic control of immunity in the periphery. Several Treg phenotypes have now been identified in the CD4 and CD8 T cell populations,suggesting their down-regulatory function in both human and animal models of autoimmunity, transplantation and tumor immunity. Here we will focus on the CD8 Treg population and their ability to specifically inhibit a pathogenic autoimmune response. This review will detail the current advances in the knowledge of CD8 Treg in the context of antigen specificity, phenotype, MHC restriction, mechanism of action, and priming. | XiaOIeiTang TrevorRFSmitl Vipin Kumar | 2005 | Cellular & Molecular Immunology2005，2，1： | 5 |
| 8 | Prevention of macrovascular complications in patients with type 2 diabetes mellitus: Review of cardiovascular safety and efficacy of newer diabetes medications显示文摘Lack of conclusive beneficial effects of strict glycemic control on macrovascular complications has been very frustrating for clinicians involved in care of patients with diabetes mellitus (DM). Highly publicized controversy surrounding cardiovascular (CV) safety of rosiglitazone resulted in major changes in United States Food and Drug Administration policy in 2008 regarding approval process of new antidiabetic medications, which has resulted in revolutionary data from several large CV outcome trials over the last few years. All drugs in glucagon-like peptide-1 receptor agonist (GLP-1 RA) and sodium-glucose cotransporter-2 (SGLT-2) inhibitor classes have shown to be CV safe with heterogeneous results on CV efficacy. Given twofold higher CV disease mortality in patients with DM than without DM, GLP-1 RAs and SGLT-2-inhibitors are important additions to clinician’s armamentarium and should be second line-therapy particularly in patients with T2DM and established atherosclerotic CV disease or high risks for CV disease. Abundance of data and heterogeneity in CV outcome trials results can make it difficult for clinicians, particularly primary care physicians, to stay updated with all the recent evidence. The scope of this comprehensive review will focus on all major CV outcome studies evaluating CV safety and efficacy of GLP-1 RAs and SGLT-2 inhibitors. | Ravi Kant Kashif M Munir Arshpreet Kaur Vipin Verma | 2019 | World Journal of Diabetes2019，10，6： | 5 |
| 9 | Self-powered pressure sensor for ultra-wide range pressure detection显示文摘传感器的下一代应该是自我动力的,没有维护,精确,并且广阔察觉到能力。尽管有压力传感器的领域里的广泛的研究和开发,大多数压力传感器的敏感在更高的压力显著地衰退,以便他们不能与一致地高的敏感检测大量压力。在这个工作,我们表明一个单个电极的摩擦电压力传感器,它能由利用自我极化的 polyvinyldifluoride-trifluoroethylene ( P ( VDF-TrFE ))的费用擦掉的压电的极化和摩擦电表面的 synergistic 效果越过全部范围与敏感的高度从 0.05~600 kPa 检测大量压力。考虑这个宽压力范围和敏感,这台设备相对以前报导的自我动力的压力传感器的展出最好的表演。这成就为许多应用便于宽范围的压力察觉,从简单人的触觉,传感器网络,聪明的机器人学,和运动应用,因此为下一代的察觉到的实现向前铺平道路设备。而且,这个工作在摩擦电 nanogenerators 处理浸透压力的关键问题并且当在摩擦电 nanogenerator 使用了时,在压电的聚合物上提供卓见进表面费用的角色。 | Kaushik Parida Venkateswarlu Bhavanasi Vipin Kumar Ramaraju Bendi Pooi See Lee | 2017 | Nano Research2017，10，10： | 4 |
| 10 | Antidiabetic,hypolipidemic and histopathological analysis of Dillenia indica (L.) leaves extract on alloxan induced diabetic rats显示文摘Objective:To investigate antidiabetic,hypolipidemic histopathological analysis of Dillenia indica(D.indica) methanolic leaves(DIME) extract in alloxan induced diabetic rat by administering oral doses(250 and 500 mg/kg body weight).Methods:Blood glucose levels were measured using blood glucose test strips with elegance glucometer on weekly intervals till the end of study(i.e.3 weeks).Other parameters e.g.liver profile,renal profile and total lipid levels were determined in normal and alloxan induced diabetic rats after oral administration of the extract for 21 days.Histopathological changes in diabetic rat organs(pancreas,liver and kidney) were also observed after extract treatment Results:Daily oral administration DIME(250 and 500 mg/kg body weight) and glibenclamide(10 mg/kg) showed beneficial effects on blood glucose level (P<0.001) as well as improving kidney,liver functions and hyperlipidaemia due to diabetes. The extract treatment also showed to enhanced serum insulin level and body weight of diabetic rats as compared to diabetic control group.Furthermore,the extract has a favorable effect on the histopathological changes of the pancreas,liver and kidney in alloxan induced diabetes. Conclusions:D.indica possess antidiabetic property as well improve body weight,liver profile, renal profile and total lipid levels.DIME has also favorable effect to inhibit the histopathological changes of the pancreas and kidney in alloxan induced diabetes. | Sunil Kumar Vipin Kumar Om Prakash | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，5： | 4 |
| 11 | Anomaly detection显示文摘 | Varun Chandola Arindam Banerjee Vipin Kumar | 2009 | ACM Computing Surveys (CSUR)2009，，3： | 4 |
| 12 | Designandconstructionof athree-dimensionalelectrodewith biomass-derived carbon current collector andwater-soluble binder for high-sulfur-loading lithium-sulfur batteries显示文摘Lithium-sulfur batteries attract lots of attention due to their high specific capacity,low cost,and environmental friendliness.However,the low sulfur utilization and short cycle life extremely hinder their application.Herein,we design and fabricate a three-dimensional electrode by a simple filtration method to achieve a high-sulfur loading.Biomass porous carbon is employed as a current collector,which not only enhances the electronic transport but also effectively limits the volume expansion of the active material.Meanwhile,an optimized carboxymethyl cellulose binder is chosen.The chemical bonding restricts the shuttle effect,leading to improved electrochemical performance.Under the ultrahigh sulfur load of 28mg/cm2,the high capacity of 18mAh/cm2 is still maintained,and stable cycling performance is obtained.This study demonstrates a viable strategy to develop promising lithium-sulfur batteries with a three-dimensional electrode,which promotes sulfur loading and electrochemical performance. | Pengfei Wang Zhe Gong Ke Ye Vipin Kumar Kai Zhu Linna Sha Jun Yan Jinling Yin Kui Cheng Guiling Wang Dianxue Cao | 2020 | Carbon Energy2020，2，4： | 3 |
| 13 | Trends in big data analytics显示文摘 | Karthik Kambatla Giorgos Kollias Vipin Kumar Ananth Grama | 2014 | Journal of Parallel and Distributed Computing2014，，： | 2 |
| 14 | 镍铁氰化物纳米粒子的合成及其多相催化无溶剂条件下苯甲醇氧化的潜能(英文)显示文摘Nickel hexacyanoferrate nanoparticles were synthesized and characterized using elemental analysis, thermal analysis, infrared spectroscopy, and X-ray diffraction. A FE-SEM image of the nickel hexacyanoferrate showed that it consists of nearly spherical particles with sizes ranging from 30 to 70 nm. The synthesized material was found to be a heterogeneous catalyst useful for the solvent-free oxidation of benzyl alcohol with H2O2 as an oxidant. A 36% conversion of benzyl alcohol to benzaldehyde was achieved under optimized reaction conditions using specific parameters such as the amount of catalyst, the temperature, the benzyl alcohol to H2O2 molar ratio, and the reaction time. | Shah R. ALI Prakash CHANDRA Mamta LATWAL Shalabh K. JAIN Vipin K. BANSAL Sudhanshu P. SINGH | 2011 | 催化学报2011，32，12： | 2 |
| 15 | Evaluation of potential landslide damming: Case study of Urni landslide,Kinnaur, Satluj valley, India显示文摘This work aims to understand the process of potential landslide damming using slope failure mechanism,dam dimension and dam stability evaluation. The Urni landslide, situated on the right bank of the Satluj River, Himachal Pradesh(India) is taken as the case study. The Urni landslide has evolved into a complex landslide in the last two decade(2000-2016) and has dammed the Satluj River partially since year 2013,damaging ~200 m stretch of the National Highway(NH-05). The crown of the landslide exists at an altitude of ~2180-2190 m above msl, close to the Urni village that has a human population of about 500.The high resolution imagery shows ~50 m long landslide scarp and ~100 m long transverse cracks in the detached mass that implies potential for further slope failure movement. Further analysis shows that the landslide has attained an areal increase of 103,900 ± 1142 m^2 during year 2004-2016. About 86% of this areal increase occurred since year 2013. Abrupt increase in the annual mean rainfall is also observed since the year 2013. The extreme rainfall in the June, 2013; 11 June(~100 mm) and 16 June(~115 mm),are considered to be responsible for the slope failure in the Urni landslide that has partially dammed the river. The finite element modelling(FEM) based slope stability analysis revealed the shear strain in the order of 0.0-0.16 with 0.0-0.6 m total displacement in the detachment zone. Further, kinematic analysis indicated planar and wedge failure condition in the jointed rockmass. The debris flow runout simulation of the detached mass in the landslide showed a velocity of ~25 m/s with a flow height of ~15 m while it(debris flow) reaches the valley floor. Finally, it is also estimated that further slope failure may detach as much as 0.80 ±0.32 million m^3 mass that will completely dam the river to a height of 76±30 m above the river bed. | Vipin Kumar Vikram Gupta Imlirenla Jamir Shovan Lal Chattoraj | 2019 | Geoscience Frontiers2019，10，2： | 2 |
| 16 | Quorum sensing inhibitors: An overview显示文摘 | Vipin Chandra Kalia | 2012 | Biotechnology Advances2012，，： | 2 |
| 17 | Evaluation of potential surface instability using finite element method in Kharsali Village,Yamuna Valley,Northwest Himalaya显示文摘Kharsali village, located in the Northwest Himalaya near the confluence of the Yamuna River and Unta Gad, is situated on a thick(>150 m) paleolandslide deposit. The village is continuously being eroded at its base by the two rivers. Cracks are noted in most houses while the ancient Shani Temple lying to the south of the village has tilted ~5° towards the northeast. Three slope sections(S-1, S-2, S-3) were modelled and analysed to determine the displacement and shear strain patterns of the slopes. Based on surface failure conditions, potential slope instability of the Kharsali village was evaluated from 2D Finite Element Method(FEM) using Shear Strain Reduction(SSR) analysis in the Phase2 software. Results indicate a critical Stress Reduction Factor(SRF) of 1.5 for the southern edge of the village(S-1) housing the Shani Temple. The development of failure surfaces at its lower portion signifies the propagating, progressive nature of the slope. The S-2 slope section is most vulnerable to slope failure, with a critical SRF of 1.08. This has been inferred by the formation of failure surfaces with displacements of 0.05-0.08 m. The S-3 section in the northern part of the Kharsali shows highest critical SRF of 2.76. The un-metalled road section in the north of the village near S-3 hasdeveloped a failure surface with displacement of 0.003-0.004 m, and a zone of subsidence. The S-3 section is relatively stable, whereas the S-2 section is the most vulnerable portion of the village. | Imlirenla JAMIR Vikram GUPTA Vipin KUMAR Glenn T.THONG | 2017 | Journal of Mountain Science2017，14，8： | 2 |
| 18 | Influence of Sputtering Pressure on the Structure and Mechanical Properties of Nanocomposite Ti-Si-N Thin Films显示文摘Nanocomposite Ti-Si-N thin films have been deposited on Si (100) substrate by direct current/radio frequency (DC/RF) magnetron sputtering. The effect of varying deposition parameters on the structure and mechanical properties of Ti-Si-N films has been investigated by characterization techniques such as X-ray diffraction (XRD), field emission scanning electron microscopy (FE-SEM), atomic force microscopy (AFM) and nanoindentation, respectively. XRD analysis of the thin films exhibit all (111), (200) and (220) peaks initially with varying sputtering pressure, but (111) peak dominates at higher sputtering pressure. The crystallite size calculated from XRD peaks shows that it increases with increasing sputtering pressure. Microstructural analysis reveals that the dense blurred grains transform into uniform grains in the films and shows porosity with increasing sputtering pressure. The surface roughness of the Ti-Si-N films increases with varying sputtering pressure. The hardness and Young s modulus values of Ti-Si-N films are 33.7 and 278.6 GPa, respectively, with 0.7 Pa sputtering pressure but it decreases with further increase in sputtering pressure due to an increase in porosity of the films. | Vipin Chawla R.Jayaganthan Ramesh Chandra | 2010 | Journal of Materials Science & Technology2010，26，8： | 2 |
| 19 | An unusual cause of radial nerve palsy显示文摘Neurapraxia 经常发生 intraoperatively 跟随拖拉损害到神经,导致通常在 5-30 星期内恢复的光线的神经麻痹。在我们的情况中,我们操作了一远侧三分之一个肱骨的柄断裂并且与 4.5 修理了它;公里限制了接触动态压缩板。手足的远侧的神经与血管的地位在恢复房间里手术后地被估计并且被发现未经触动并且光线的神经的所有感觉马达的功能是正常的。在第二手术后的天,跟随吸排水管移动和调味品,与手腕落下一起的耐心的发达立即的光线的神经麻痹。我们考察了文学并且没为神经麻痹发现明显的原因并且当在否定压力移开吸排水管时,断定它由于对光线的神经的拖拉损害。 | Hemendra Kumar Agrawal Vipin Khatkar Mohit Garg Balvinder Singh Ashish Jaiman Vinod Kumar Sharma | 2014 | Chinese Journal of Traumatology2014，17，3： | 2 |
| 20 | T-connected autotransformer-based 24-pulse AC-DC converter for variable frequency induction motor drives显示文摘 | Bhim Singh Bhuvanewari G Vipin Garg | 2006 | IEEE Transactions on Energy Conversion2006，21，3： | 1 |
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