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    题名 作者 年代 出处 被引量
1欧洲新生儿呼吸窘迫综合征防治共识指南:2016版显示文摘新生儿呼吸窘迫综合征(RDS)是早产儿的重要疾病,尽管治疗手段不断成熟,低龄早产儿存活率逐渐增高,但支气管肺发育不良(BPD)发病率也随之升高,其中部分原因是减少了出生后激素的使用.2006年以来,来自欧洲许多国家的新生儿专家每3年一次回顾最新文献,就RDS或有RDS风险早产儿的防治达成共识,立志于改善欧洲新生儿的预后.欧洲RDS防治指南2007年开始发布,2010年和2013年进行了更新,期间获得了欧洲围产医学学会的大力支持.RDS是由于肺表面活性物质(PS)缺乏导致生后早期出现呼吸窘迫,典型临床表现随着防治手段的改进发生了巨大变化.DavidG.Sweet Virgilio Carnielli Gorm Greisen Mikko Hallman Eren Ozek Richard Plavka Ola Didrik Saugstad Umberto Simeoni Christian P. Speer Maximo Vento Gerard H. A. Visser Henry L. Halliday 2017中华儿科杂志2017,55,3:90
2最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL 2014神经病学与神经康复学杂志2014,11,3:31
3Experimental investigation on breaching of embankments显示文摘Breaching of embankments has recently drawn more and more attention due to its importance in the development of early warning systems for embankment failures,in the evacuation plans of people at risk,in the design method of embankments based on a risk-approach,etc. The erosion process observed during embankment breaching tests in the laboratory and the analysis of the results are described in this paper. Five embankments,one constructed with pure sand,four with different sand-silt-clay mixtures were tested. The height of the embankments was 75 cm and the width at the crest was 60 cm. Examination of the data from these tests indicated that headcut erosion played an important role in the process of breach growth in the embankments made of cohesive soil mixtures. Flow shear erosion,fluidization of the headcut slope surface,undermining of the headcut due to impinging jet scour and discrete soil mechanical slope mass failure from the headcut were all observed during these tests. For the embankment constructed with pure sand,the breach erosion process was dominated by shear erosion,which led to a gradual and relatively uniform retreat of the downstream slope. The cohesive proportion in the sand-silt-clay mixtures strongly slowed down the erosion process.ZHU YongHui VISSER P J VRIJLING J K WANG GuangQian 2011Science China(Technological Sciences)2011,54,1:17
4Management of recurrent rectal cancer:A population based study in greater Amsterdam显示文摘AIM: To analyze,retrospectively in a population-based study,the management and survival of patients with recurrent rectal cancer initially treated with a macroscopically radical resection obtained with total mesorectal excision (TME). METHODS: All rectal carcinomas diagnosed during 1998 to 2000 and initially treated with a macroscopically radical resection (632 patients) were selected from the Amsterdam Cancer Registry. For patients with recurrent disease,information on treatment of the recurrence was collected from the medical records. RESULTS: Local recurrence with or without clinically apparent distant dissemination occurred in 62 patients (10%). Thirty-two patients had an isolated local recurrence. Ten of these 32 patients (31%) underwent radical re-resection and experienced the highest survival (three quarters survived for at least 3 years). Eight patients (25%) underwent non-radical surgery (median survival 24 mo),seven patients (22%) were treated with radio-and/or chemotherapy without surgery (median survival 15 mo) and seven patients (22%) only received best supportive care (median survival 5 mo). Distant dissemination occurred in 124 patients (20%) of whom 30 patients also had a local recurrence. The majority (54%) of these patients were treated with radio-and/or chemotherapy without surgery (median survival 15 mo). Twenty-seven percent of these patients only received best supportive care (median survival 6 mo),while 16% underwent surgery for their recurrence. Survival was best in the latter group (median survival 32 mo). CONCLUSION: Although treatment options and survival are limited in case of recurrent rectal cancer after radical local resection obtained with TME,patients can benefit from additional treatment,especially if a radical resection is feasible.Roel Bakx Otto Visser Judith Josso Sybren Meijer J Frederik M Slors J Jan B van Lanschot 2008World Journal of Gastroenterology2008,14,39:17
5堤坝溃决试验研究显示文摘近年来,由于在堤坝溃决的早期预警、应预案编制以基于风的堤坝设计方法等中的重要作用,堤坝溃决问题日渐受关注.本文介绍了在验室堤坝溃决试验中观察的堤坝溃决冲刷过程以试验分析结果.共进行了5组堤坝溃决试验,其中4组的试验材料为不同掺混比例的沙-粉沙-粘土混合料,另外1组试验材料为沙.试验堤坝高75 m,坝顶宽60 cm.试验结果示,'陡坎'冲刷(溯源冲刷)在由粘性混合土料填筑的堤坝溃决过程中扮演着非常重要的角色.在试验中观察了水流切冲刷、溯源'陡坎'表层流化、由溃决洪水射流冲击引起的'陡坎'基和'陡坎'的土力学坍失稳等冲刷象.对于沙质堤坝,其溃决过程主要由水流切冲刷主,其下游坝坡逐渐地、比较均匀地后移.沙-粉沙-粘土混合料中的粘性土部分极大地缓了堤坝溃决冲刷的速度.朱勇辉 Visser P J Vrijling J K 王光谦 2011中国科学:技术科学2011,41,2:13
6Duodenal adenocarcinoma: Advances in diagnosis and surgical management显示文摘Duodenal adenocarcinoma is a rare but aggressive malignancy. Given its rarity, previous studies have traditionally combined duodenal adenocarcinoma(DA) with either other periampullary cancers or small bowel adenocarcinomas, limiting the available data to guide treatment decisions. Nevertheless, management primarily involves complete surgical resection when technically feasible. Surgery may require pancreaticoduodenectomy or segmental duodenal resection; either are acceptable options as long as negative margins are achievable and an adequate lymphadenectomy can be performed. Adjuvant chemotherapy and radiation are important components of multi-modality treatment for patients at high risk of recurrence. Further research would benefit from multiinstitutional trials that do not combine DA with other periampullary or small bowel malignancies. The purpose of this article is to perform a comprehensive review of DA with special focus on the surgical management and principles.Jordan M Cloyd Elizabeth George Brendan C Visser 2016World Journal of Gastrointestinal Surgery2016,8,3:13
7三维超声心动图测定正常人及二尖瓣病变伴或不伴房颤患者左心耳容量及其收缩功能显示文摘目的 :探讨三维超声心动图评价左心耳功能的价值。方法 :采用三维超声心动图对 5 2例正常人及二尖瓣病变伴或不伴心房纤颤患者测定左心耳容量及其收缩功能 ,并与二维超声心动图和多普勒超声心动图比较。结果 :根据左心耳容量测定计算出的左心耳射血分数 (EFv)与左心耳峰值血流排空速度 (Pev)相关良好 (r=0 .818,P<0 .0 1) .根据左心耳面积测定计算出的左心耳射血分数 (EFa)与 Pev的相关性低于前者 (r=0 .744 4,P<0 .0 1)。将所有患者的 EFv与 EFa进行比较 ,虽然两者间未见明显差异 (P>0 .0 5 ) ,但在重复性检验中 EFa的范围和两测量数值之差的均数加减标准差都大于 EFv的相应数值 ,左心耳容量在正常人明显小于有二尖瓣病变的患者 ,而收缩功能则前者明显高于后者 (P值均 <0 .0 1) .在相同二尖瓣病变患者之间进行比较 ,合并房颤者左心耳容量大于窦性心率者 ,而左心耳收缩功能则前者低于后者 (P值均 <0 .0 5 )。另外 ,二尖瓣病变合并房颤者的左心耳自发性“超声造影”发生率高于窦性心率者。结论 :用三维超声心动图测量左心耳容量和评价其收缩功能是可行的 ,评价左心耳功能时较二维超声心动图更准确 ,二尖瓣病变患者的左心耳容量增加 ,收缩功能减低 ,常伴左心耳自发性“超声造影”,上述改变在合并房颤者更?李越 Herman FJ Mannaerts OttoKamp Gabriel Valocik CeesA Visser 2000中国超声医学杂志2000,16,4:12
8Folate Biofortification of Potato by Tuber-Specific Expression of Four Folate Biosynthesis Genes显示文摘微量元素的不够的饮食的吸入,是隐藏饥饿知道,是破坏全球负担,影响 20 亿个人。folates (维生素 B9 ) 的缺乏,被知道在 C 1 新陈代谢起一个中央作用,每年在至少 1/4 百万个人引起出生缺点。在庄稼提高自然地发生的 folates 的水平的 Biofortification 种,证明是在战斗的一个有效、划算的工具叶酸的缺乏。以前,叶酸的生合成基因 GTPCHI 和模数转换器的介绍,证明是在米饭和西红柿的成功的 biofortification 策略,结果不够足够地在土豆 tubers 增加叶酸的层次。这里,我们提供概念的一个证明 HPPK/DHPS 或 FPGS 的那另外的介绍,在 mitochondrial 的下游的基因叶酸的生合成,启用 folates 的扩大到令人满意的层次(12 褶层) 并且在 tubers 的长期的存储之上保证叶酸的稳定性。在结论,这设计策略能在叶酸积累的土豆栽培变种的创造担任一个模型,在消费土豆的人口受不了容易地适用叶酸的缺乏。Jolien De Lepeleire Simon Strobbe Jana Verstraete Dieter Blancquaert Lars Ambach Richard G.F. Visser Christophe Stove Dominique Van Der Straeten 2018Molecular Plant2018,11,1:12
925-羟维生素D和甲状旁腺激素与高血压的相关性显示文摘有研究证实,维生素D缺乏和甲状旁腺激素(PTH)过高与高血压的发生密切相关。维生素D缺乏不仅可以影响肾素血管紧张素系统及PTH水平,而且可以直接参与血管炎性反应,影响高血压的发生发展。PTH可以通过促进血管炎性反应及血管钙化等参与高血压的进展。目前还没有前瞻性研究同时评估维生素D和PTH水平与高血压发病的关系。该研究分析多民族动脉粥样硬化研究的前瞻性数据,发现低水平25羟维生素D[25(OH)D]和高水平PTH与高血压发病相关,特别是在肥胖人群中。但在校正混杂因素后,25(OH)D水平与高血压发病的相关性无统计学意义,而PTH水平与高血压发病仍然相关。鉴于维生素D缺乏和PTH过量在人群中是普遍现象,该研究对于更好地了解高血压发病机制,在人群中开展高血压预防工作有重要意义。van Ballegooijen AJ Kestenbaum B Sachs MC de Boer IH Siscovick DS Hoofnagle AN Ix JH Visser M Brouwer IA 练桂丽 叶鹏 2014中华高血压杂志2014,22,6:10
10Analysis of the meiosis in the F_1 hybrids of Longiflorum × Asiatic(LA) of lilies(Lilium) using genomic in situ hybridization显示文摘Longiflorum and Asiatic lilies of the genus Lilium of the family Liliaceae are two important groups of modern lily cultivars.One of the main trends of lily breeding is to realize introgression between these groups.With cut style pollination and embryo rescue,distant hybrids between the two groups have been obtained.However,the F1 hybrids are highly sterile or some of them could produce a small number of 2n gametes,and their BC1 progenies are usually triploids.Dutch lily breeders have selected many cultivars from these BC1 progenies based on their variation.It is presumably suggested that such variation could be caused by intergenomic recombination and abnormal meiosis during gamete formation in F1 hybrids of Longiflorum × Asiatic(LA) hybrids in Lilium.Therefore,the meiotic process of ten F1 LA hybrids was cytologically investigated using genomic in situ hybridization and traditional cytological methods in the present research.The results showed that:at metaphase I,the homoeologous chromosome pairing among different F1 hybrids ranged from 2.0 to 11.4 bivalents formed by homoeologous chromosomes per pollen mother cell(PMC),and very few multivalents,and even very few bivalents were formed by two chromosomes within one genome rather than homoeologous chromosomes in some PMCs;at anaphase I,all bivalents were disjoined and most univalents were divided.Both the disjoined bivalents(half-bivalents) and the divided univalents(sister chromatids) moved to the opposite poles,and then formed two groups of chromosomes;because the two resulting half-bivalents retained their axes in the cell undisturbed,many crossover types,including single crossovers,three strand double crossovers,four strand double crossovers,four strand triple crossovers,and four strand multiple crossovers between the non-sister chromatids in the tetrads of bivalents,were clearly inferred by analyzing the breakpoints on the disjoined bivalents.The present investigation not only explained the reason for sterility of the F1 LA hybrids and the variation of their BC1 progenies,but also provided a new method to analyze crossover types in other F1 interspecific hybrids as well.Shujun Zhou Munikote S. Ramanna Richard G.E Visser Jaap M. van Tuyl 2008Journal of Genetics and Genomics2008,35,11:8
11三维超声心动图测定左心耳容量及其收缩功能的初步研究显示文摘目的 观察三维超声心动图测定左心耳容量的可行性。方法 对 10名患者行多平面经食管超声心动图 (TEE)检查。应用三维超声心动图采取圆盘总和方法 (disksummation)测定左心耳舒张末期容量 (EDV)和左心耳收缩末期容量 (ESV)。用二维超声心动图测定左心耳舒张末期面积 (EDA)和左心耳收缩末期面积(ESA)。上述左心耳容量和面积的测定均在二个独立的观察者之间以及同一观察者两次观察间重复进行。由三维超声心动图容量测定结果计算出左心耳的射血分数 (EFv) ,由二维超声心动图的面积测定结果计算出左心耳射血分数 (EFa)。结果 三维超声心动图测定左心耳EDV为 ( 19.5± 10 .9)ml,ESV为 ( 13 .5± 9.5 )ml ,EFv为0 .3 5± 0 .14。二维超声心动图测定左心耳EDA为 ( 8.7± 2 .2 )cm2 ,ESV为 ( 5 .9± 3 .5 )cm2 ,EFa为 0 .3 5± 0 .2 2。以上测量内容在观察者之间及观察者内的重复性检验中均未见显著性差异 ,EFv与EFa之间亦无显著性差异。但无论在观察者间或观察者内的重复性检验中EFa的范围和两测量数值之差均大于EFv的相应值。结论 三维超声心动图测量左心耳容量和评价其收缩功能是可行的 ,这种测定方法可能有助于改善二维超声心动图评价左心耳功能的准确性。李越 Otto Kamp Herman FJ Mannaerts Gabriel Valocik Cees A Visser 2000中华超声影像学杂志2000,9,5:6
12High-density SNP-based genetic maps for the parents of an outcrossed and a selfed tetraploid garden rose cross, inferred from admixed progeny using the 68k rose SNP array显示文摘Dense genetic maps create a base for QTL analysis of important traits and future implementation of marker-assisted breeding.In tetraploid rose,the existing linkage maps include<300 markers to cover 28 linkage groups(4 homologous sets of 7 chromosomes).Here we used the 68k WagRhSNP Axiom single-nucleotide polymorphism(SNP)array for rose,in combination with SNP dosage calling at the tetraploid level,to genotype offspring from the garden rose cultivar‘Red New Dawn’.The offspring proved to be not from a single bi-parental cross.In rose breeding,crosses with unintended parents occur regularly.We developed a strategy to separate progeny into putative populations,even while one of the parents was unknown,using principle component analysis on pairwise genetic distances based on sets of selected SNP markers that were homozygous,and therefore uninformative for one parent.One of the inferred populations was consistent with self-fertilization of‘Red New Dawn’.Subsequently,linkage maps were generated for a bi-parental and a self-pollinated population with‘Red New Dawn’as the common maternal parent.The densest map,for the selfed parent,had 1929 SNP markers on 25 linkage groups,covering 1765.5 cM at an average marker distance of 0.9 cM.Synteny with the strawberry(Fragaria vesca)genome was extensive.Rose ICM1 corresponded to F.vesca pseudochromosome 7(Fv7),ICM4 to Fv4,ICM5 to Fv3,ICM6 to Fv2 and ICM7 to Fv5.Rose ICM2 corresponded to parts of F.vesca pseudochromosomes 1 and 6,whereas ICM3 is syntenic to the remainder of Fv6.Mirjana Vukosavljev Paul Arens Roeland E Voorrips Wendy P C van't Westende G D Esselink Peter M Bourke Peter Cox W Eric van de Weg Richard G F Visser Chris Maliepaard Marinus J M Smulders 2016Horticulture Research2016,3,1:6
13无粘性土堤的溃堤模型显示文摘以实验室及现场模型试验中观察到的溃堤机理为基础,开发了一个无粘性土(沙)堤的溃堤模型。模型用现场试验的数据校准,又用实验室试验的数据进行验证,计算与观测值间的拟合结果令人满意。模型还对一个溃堤实例进行了模拟,计算结果与目测报告基本一致。P.J. Visser 朱勇辉 2003长江科学院院报2003,20,3:5
14Is overhydration in peritoneal dialysis patients associated with cardiac mortality that might be reversible?显示文摘AIM To study the relationship between overhydration(OH) in peritoneal dialysis(PD) patients and cardiac mortality.METHODS OH, as measured by body composition monitor(BCM), is associated with increased mortality in dialysis patients. BCM has been used to guide treatment on the assumption that correcting OH will improve cardiac morbidity and mortality although data demonstrating causality that is reversible is limited. We wished to determine if OH in PD patients predicted cardiac mortality, and if there was a correlation between OH and cardiac troponin-T(cT n T) levels. Finally, we wished to determine if improving OH values would lead to a decrement in cT n T. All prevalent PD patients over the study period of 57 mo who had contemporaneous BCM and cT nT measurements were followed irrespective of transplantation or PD technique failure. We also studied a cohort of patients with who had severe OH(> +2L).The Fresenius Body Composition Monitor was used to obtain hydration parameters. cT nT levels were done as part of routine clinical care. Data was analysed using SPSS version 20.0.RESULTS There were 48 deaths in the 336 patients. The patients that died from cardiac or non-cardiac causes were similar with respect to their age, incidence of diabetes mellitus, gender, ethnicity and cause of renal failure. However, the patients with cardiac causes of death had significantly shorter dialysis vintage(10.3 mo vs 37.0 mo, P < 0.0001) and were significantly more overhydrated by BCM measurement(2.95 L vs 1.35 L, P < 0.05). The mean(standard error of the means) hydration status of the 336 patients was +1.15(0.12) L and the median [interquartile range(IQR)] cT nT level was 43.5(20-90) ng/L. The cT nT results were not normally distributed and were therefore transformed logarithmically. There was a statistically significant correlation between Log(cT nT) with the OH value(Spearman r value 0.425, P < 0.0001). We identified a sub-group of patients that were severely overhydrated; median(IQR) hydration at baseline was +2.7(2.3 to 3.7) L. They were followed up for a minimum of 6 mo. Reduction in OH values in these patients over 6 mo correlated with lowering of cT nT levels(Spearman r value 0.29, P < 0.02). CONCLUSION Patients that were overhydrated had higher cT nT, and had deaths that were more likely to be cardiac related. Reduction in OH correlated with lowering of cT nT.Elizabeth Oei Klara Paudel Annemarie Visser Hazel Finney Stanley L Fan 2016World Journal of Nephrology2016,5,5:4
15The Bemisia tabaci species complex: Additions from different parts of the world显示文摘Bemisia tabaci 是在许多庄稼的大多数威胁的害虫之一。我们定序 mitochondrial 细胞色素 oxidase 的部分我 whitefly,人口在印度尼西亚,泰国,印度和中国收集了的从五十的基因。细胞色素 oxidase 的十九个唯一的序列(haplotypes ) 我在这些人口被识别。他们与在数据库可得到的序列被相结合,导致 407 haplotypes 的一个总数并且和九外集团就职分析了。一棵种系发生的树用最大的可能性的方法被计算。树证明在以前的研究被发现的所有组也是在我们的学习的现在。另外,七个新组基于新 haplotypes 被识别。大多数 B。基于他们的地理起源组织的 tabaci haplotypes。二个组被发现有世界范围的分布。我们的结果显示那我们在 B 附近的种类建筑群上的知识。tabaci 仍然是远非完全的。Syarifin Firdaus Ben Vosman Nurul Hidayati Ence Darmo Jaya Supena Richard G.F. Visser Adriaan Willem van Heusden 2013Insect Science2013,20,6:4
16Facilitating transparency in spinal cord injury studies using data standards and ontologies显示文摘Extract Progress in developing robust therapies for spinal cord injury(SCI),traumatic brain injury(TBI)and peripheral nerve injury has been slow.A great deal has been learned over the past 30 years regarding both the intrinsic factors and the environmental factors that regulate axon growth,but this large body of information has not yet resulted in clinically available therapeutics.This therapeutic bottleneck has many root causes,but aVance P.Lemmon Saminda Abeyruwan Ubbo Visser John L.Bixby 2014Neural Regeneration Research2014,9,1:4
17Neutrophil transcriptional profile changes during transii from bone marrow to sites of inflammation显示文摘Flavia S Lakschevitz Michelle B Visser Chunxiang Sun Michael Glogauer 2015Cellular & Molecular Immunology2015,12,1:3
18慢性心力衰竭时的贫血不仅与肾脏灌注受损和促红细胞生成素减少有关,亦与液体潴留有关显示文摘目的:贫血在慢性心力衰竭(CHF)人群中普遍,但其原因尚不明确。本研究旨在观察CHF患者中贫血与肾脏灌注、促红细胞生成素(EPO)生成及液体潴留之间的关系。方法和结果:作者观察了97例CHF患者,其中15例伴有贫血(男性Hb〈130g/L,女性Hb〈120g/L),但无补血剂缺乏。分别用连续灌注^125I-碘酞酸盐的清除率和分布容积来检测肾小球滤过率(GFR)和细胞外容积(ECV)。有效肾血浆流量(ERPF)则依据^131I-邻碘马尿酸钠的清除率确定。贫血的CHF患者表现出显著降低的GFR、ERPF和EPO生成(分别为P=0.002、P=0.005和P=0.001),以及增加的ECV(P=0.015)。Westenbrink B.D. Visser F.W. Voors A.A. 孙凯 2007世界核心医学期刊文摘(心脏病学分册)2007,3,7:3
19SBD在重组蛋白质中位移对其酶活性及与淀粉粒结合性能的影响显示文摘 将环状糊精糖基转移酶的SBD基因编码序列连接到萤光素酶基因的 5′ 端(SBD LUC)后,重组基因通过农杆菌介导导入马铃薯植株中.对重组蛋白在转基因淀粉粒中的定位与积累、重组蛋白中SBD与淀粉的亲和性以及萤光素酶的活性进行了分析比较.结果表明: 重组蛋白在马铃薯淀粉粒中获得了特异性表达, 当C 端SBD移位到重组萤光素酶蛋白的N 端后, SBD和淀粉的亲和性与LUC SBD重组蛋白质比较有所下降, 但萤光素酶活性则与马铃薯遗传背景有关.季勤 Jean-Paul Vincken Krit Raemakers Lucas Carolus Josephus Maria Suurs Richard Gerardus Franciscus Visser 2005南京师大学报(自然科学版)2005,28,1:3
20Differences between the floras of the North and South Moluccas (Indonesia)显示文摘The north and south Moluccas (Indonesia)have very different geotectonic origins and,due to that,a difference in flora is to be expected.The north Moluccas moved westwards along the north coast of New Guinea to their present position,the south Moluccas moved north from Australia.On the other hand,a comparable climate in both areas and (partial)submergence during tectonic movement may have equalized both floras.Collection data from Naturalis Biodiversity Center on 1559species in 121families treated in Flora Malesiana were collected for the Moluccas,Sulawesi,and Western New Guinea (latitudes 9.2°S and 5.6~N and longitudes 118.8°E and 141°E)and georeferenced.Species Distribution Models (SDMs)were made,based on least correlated climate and edaphic variables,using only those species that were present in 5or more grid cells of 5-arc minutes and models were tested for deviation from random.Both areas differ significantly and share only 50%-65% of their species.The 348 significant SDMs differ much less,though still significantly,sharing 91%of the species.Despite strong climatic and edaphic similarities between the North and South Moluccas,they differ greatly in species composition,which is in support of geotectonic reconstructions.The differences between the North and South Moluccas suggest that the continuous dispersal barriers and tectonic backgrounds have influenced their current flora.Anne L.J.Rutgrink Michael Visser Peter C.van Welzen 2018Journal of Systematics and Evolution2018,56,6:2
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