|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Phased,chromosome-scale genome assemblies of tetraploid potato reveal a complex genome,transcriptome,and predicted proteome landscape underpinning genetic diversity显示文摘Cultivated potato is a clonally propagated autotetraploid species with a highly heterogeneous genome.Phased assemblies of six cultivars including two chromosome-scale phased genome assemblies revealed extensive allelic diversity,including altered coding and transcript sequences,preferential allele expression,and structural variation that collectively result in a highly complex transcriptome and predicted proteome,which are distributed across the homologous chromosomes.Wild species contribute to the extensive allelic diversity in tetraploid cultivars,demonstrating ancestral introgressions predating modern breeding efforts.As a clonally propagated autotetraploid that undergoes limited meiosis,dysfunctional and deleterious alleles are not purged in tetraploid potato.Nearly a quarter of the loci bore mutations are predicted to have a high negative impact on protein function,complicating breeder’s efforts to reduce genetic load.The StCDF1 locus controls maturity,and analysis of six tetraploid genomes revealed that 12 allelic variants of StCDF1 are correlated with maturity in a dosage-dependent manner.Knowledge of the complexity of the tetraploid potato genome with its rampant structural variation and embedded deleterious and dysfunctional alleles will be key not only to implementing precision breeding of tetraploid cultivars but also to the construction of homozygous,diploid potato germplasm containing favorable alleles to capitalize on heterosis in F1 hybrids. | Genevieve Hoopes Xiaoxi Meng John P.Hamilton Sai Reddy Achakkagari Fernanda de Alves Freitas Guesdes Marie E.Bolger Joseph J.Coombs Danny Esselink Natalie R.Kaiser Linda Kodde Maria Kyriakidou Brian Lavrijssen Natascha van Lieshout Rachel Shereda Heather K.Tuttle Brieanne Vaillancourt Joshua C.Wood Jan Mde Boer Nolan Bornowski Peter Bourke David Douches Herman Jvan Eck Dave Ellis Max J.Feldman Kyle M.Gardner Johannes C.P.Hopman Jiming Jiang Walter S.De Jong Joseph C.Kuhl Richard G.Novy Stan Oome Vidyasagar Sathuvalli Ek Han Tan Remco A.Ursum M.Isabel Vales Kelly Vining Richard G.F.Visser Jack Vossen G.Craig Yencho Noelle L.Anglin Christian W.B.Bachem Jeffrey B.Endelman Laura M.Shannon Martina V.Stromvik Helen H.Tai Bjorn Usadel C.Robin Buell Richard Finkers | 2022 | Molecular Plant2022，15，3： | 4 |
| 2 | Genome architecture and tetrasomic inheritance of autotetraploid potato显示文摘Potato(Solanum tuberosum)is the most consumed non-cereal food crop.Most commercial potato cultivars are autotetraploids with highly heterozygous genomes,severely hampering genetic analyses and improvement.By leveraging the state-of-the-art sequencing technologies and polyploid graph binning,we achieved a chromosome-scale,haplotype-resolved genome assembly of a cultivated potato,Cooperation-88(C88).lntra-haplotype comparative analyses revealed extensive sequence and expression differences in this tetraploid genome.We identified haplotype-specific pericentromeres on chromosomes,suggesting a distinct evolutionary trajectory of potato homologous centromeres.Furthermore,we detected double reduction events that are unevenly distributed on haplotypes in 1021 of 1034 selfing progeny,a feature of autopolyploid inheritance.By distinguishing maternal and paternal haplotype sets in C88,we simulated the origin of heterosis in cultivated tetraploid with a survey of 3110 tetra-allelic loci with deleterious mutations,which were masked in the heterozygous condition bytwo parents.This study provides insights into the genomic architecture of autopolyploids and will guide their breeding. | Zhigui Bao Canhui Li Guangcun Li Pei Wang Zhen Peng Lin Cheng Hongbo Li Zhiyang Zhang Yuying Li Wu Huang Mingwang Ye Daofeng Dong Zhukuan Cheng Peter VanderZaag Evert Jacobsen Christian W.B.Bachem Suomeng Dong Chunzhi Zhang Sanwen Huang Qian Zhou | 2022 | Molecular Plant2022，15，7： | 4 |
| 3 | Visualization of differential gene expression using a novel method of RNA fingerprinting based on AFLP: Analysis of gene expression during potato tuber development显示文摘 | Christian W.B.Bachem Rutger S.Hoeven Steef M.Bruijn DickVreugdenhil MarcZabeau Richard G.F.Visser | 2003 | The Plant Journal2003，，5： | 2 |
| 4 | Understanding Genetic Load in Potato for Hybrid Diploid Breeding显示文摘Recently, Zhang et al.(2019) have managed to provide abundant evidence to support long-held theories regarding mechanisms of inbreeding depression and potential effects of heterosis that are likely to have a considerable impact on potato breeding in the future (Figure 1). Despite its large genetic variation regarding yield, harvest index, and water use efficiency, potato breeding has attained only negligible advances in the most important breeding goals such as yield, tuber quality, and abiotic stress tolerance, and only modest progress in pathogen resistance. This low level of improvement is clearly due to the complexity of breeding a heterozygous tetraploid outbreeder rather than to the lack of genetic potential available in wild and cultivated material. In contrast, breeding at the diploid level, in particular in combination with self-compatibility, will allow the fixation of beneficial alleles to homozygosity. | Christian W.B.Bachem Herman J.van Eck Michiel E.de Vries | 2019 | Molecular Plant2019，12，7： | 1 |
| 5 | Visualization of differential gene expression using a novel method of RNA fingerprinting based on AFLP: Analysis of gene expression during potato tuber development显示文摘 | Christian W.B.Bachem Rutger S.Hoeven Steef M.Bruijn DickVreugdenhil MarcZabeau Richard G.F.Visser | 2003 | The Plant Journal2003，，5： | 1 |
| 6 | A potato tuber‐expressed mRNA with homology to steroid dehydrogenases affects gibberellin levels and plant development显示文摘 | Christian W.B.Bachem BeatrixHorvath LuisaTrindade MargoClaassens EvertDavelaar WilcoJordi Richard G. F.Visser | 2002 | The Plant Journal2002，，6： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员