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| 1 | Small molecule compound induces chromatin de-condensation and facilitates induced pluripotent stern cell generation显示文摘 | Xiaoyuan Wei Yueting Chen Yongyu Xu YangZhan Ru Zhang Min Wang Qiuhong Hua Haifeng Gu Fajun Nan Xin Xie | 2014 | Journal of Molecular Cell Biology2014，8，5： | 13 |
| 2 | Polymorphisms of chemokine receptors and its ligand alleles influencing genetic suscepti-bity to HIV-1 infection in eight ethnic groups in Chinese mainland显示文摘Limited genetic information is available concerning the polymorphisms of HIV-1 resistant genes in indigenous Chinese populations. The aim of this study is to identify the allelic frequencies of the chemokine and chemokine receptor genes in the Chinese mainland. Genomic DNA samples extracted from whole blood of 2318 subjects were analyzed by using PCR or PCR/restriction fragment length polymorphism (RFLP) assays, and further confirmed by direct DNA sequencing. Higher frequencies of mutant CCR2-64I (19.15%-28.79%) and SDF1-3’A (19.10% -29.86%) alleles were found in subjects of 8 ethnic groups in the Chinese mainland. In contrast, the △32 mutation in CCRS gene occurs at a very low frequency (0.0016, n=1287) in Han population. A relatively high frequency of CCR5-wt/△32 heterozygotes was observed in Uygurian and Mongolian populations. No A32 mutation allele was detected in Tibetan and other 4 ethnic groups in Yunnan Province. There was no CCR5-m303 mutation in subjects of any ethnic group in the Chinese | WANG Fusheng JIN lei LIU Mingxu HONG Weiguo SHI Hong LEI Zhouyun WANG Jiming DU Qingyou HOU Jing ZHANG Bing JIANG Jiandong WANG Yue LI Yueqi XU Anlong HUANG Honglian LIU Fajun | 2001 | Chinese Science Bulletin2001，46，12： | 6 |
| 3 | Magnetic plasmon resonances in nanostructured topological insulators for strongly enhanced light-MoS_(2) interactions显示文摘Magnetic resonances not only play crucial roles in artificial magnetic materials but also offer a promising way for light control and interaction with matter.Recently,magnetic resonance effects have attracted special attention in plasmonic systems for overcoming magnetic response saturation at high frequencies and realizing high-performance optical functionalities.As novel states of matter,topological insulators(TIs)present topologically protected conducting surfaces and insulating bulks in a broad optical range,providing new building blocks for plasmonics.However,until now,high-frequency(e.g.visible range)magnetic resonances and related applications have not been demonstrated in TI systems.Herein,we report for the first time,to our knowledge,a kind of visible range magnetic plasmon resonances(MPRs)in TI structures composed of nanofabricated Sb_(2)Te_(3) nanogrooves.The experimental results show that the MPR response can be tailored by adjusting the nanogroove height,width,and pitch,which agrees well with the simulations and theoretical calculations.Moreover,we innovatively integrated monolayer MoS_(2) onto a TI nanostructure and observed strongly reinforced light-MoS_(2) interactions induced by a significant MPR-induced electric field enhancement,remarkable compared with TI-based electric plasmon resonances(EPRs).The MoS_(2) photoluminescence can be flexibly tuned by controlling the incident light polarization.These results enrich TI optical physics and applications in highly efficient optical functionalities as well as artificial magnetic materials at high frequencies. | Hua Lu Zengji Yue Yangwu Li Yinan Zhang Mingwen Zhang Wei Zeng Xuetao Gan Dong Mao Fajun Xiao Ting Mei Weiyao Zhao Xiaolin Wang Min Gu Jianlin Zhao | 2020 | Light(Science & Applications)2020，9，1： | 3 |
| 4 | Selective excitation of a three-dimensionally oriented single plasmonic dipole显示文摘We experimentally demonstrate a scheme to deterministically excite a three-dimensionally oriented electric dipole in a single Au nanosphere by using a tightly focused radially polarized beam whose focal field possesses polarization states along three-dimensional(3D) orientations owing to the spatial overlap between longitudinal and radial electric field components. Experiment observations indicate that the orientation of an excited dipole moment gradually changes from out-of-plane to in-plane when the nanosphere is moved away from the beam center, which is reconfirmed by full-wave simulations. Moreover, rigorous calculation based on Mie theory reveals that a reduced effective ambient permittivity accompanies the rotation of the dipole moment, leading to a blue-shifted and narrowed resonance peak. We envision that our results could find applications in detecting the 3D orientation of isolated molecules and benefit the fine manipulation of light–matter interactions at the single-molecule level. | FAJUN XIAO GUANGLIN WANG XUETAO GAN WUYUN SHANG SHIYIN CAO WEIREN ZHU TING MEI MALIN PREMARATNE JIANLIN ZHAO | 2019 | Photonics Research2019，7，6： | 3 |
| 5 | Development of superconducting microcalorimeters for the HUBS mission显示文摘Hot Universe Baryon Surveyor(HUBS)is a proposed space‐borne observatory for X‐ray astronomy.The primary scientific objectives of the mission are to fill a void in probing the ecosystem of galaxies and thus to advance our understanding of galaxy formation and evolution,which is of fundamental importance in cosmology.More specifically,HUBS aims at directly detecting soft X‐ray emission from diffuse gas of temperature exceeding 106 K,which is theoretically postulated to permeate the large structures in the cosmic web and also fill the extended halo of galaxies.However,although some indirect evidence exists,the presence of such hot gas has yet to be well established observationally,due to the lack of effective tools to probe it.In this paper,we describe the design of HUBS,focusing on its scientific payload,which employs superconducting technologies in the detector system,and particularly on progress in the development of superconducting microcalorimeters. | Sifan Wang Guole Wang Naihui Chen Yanling Chen Wei Cui Jiao Ding Fajun Li Yajie Liang Qian Wang Yeru Wang | 2022 | Superconductivity2022，，4： | 2 |
| 6 | Synthesis and anion recognition of neutral receptors based on multiamide calix[4]arene显示文摘Two multiamide calyx[4].arenas(5,6)were synthesized and characterized by IR,1H NMR,MS and elemental analysis.The binding properties of receptors with some anions (p-O2NphOpO2-3,p-O2NphO-,H2PO-4,Ac-,CI-,Br- and I-)Were studied by UV-Vis spectra.The results indicate that the tetraamide calix[4]arenas (5,6) have a good selectivity to the anions containing aromatic ring (p-O2NphOpO2-3,p-O2NphO-).The 1:1 complexes between host and guest were formed through multiple hydrogen bonding and π-π interactions.The hosts 5 and 6 also show a definite binding ability for the anions (H2PO-4,Ac-,CI-) that have no ultraviolet absorption,which provides a simple method of spectrum detection for these anions. | LIU Shunying WANG Fajun WEI Lanhua XIAO Wang MENG Lingzhi HE Yongbing | 2004 | Science China Chemistry2004，47，2： | 2 |
| 7 | Effect of GR24 Stereoisomers on Plant Development in Arabidopsis显示文摘 | Suhua Li Linhai Chen Yuwen Li Ruifeng Yao Fei Wang Mai Yang Min Gu Fajun Nan Daoxin Xie Jianbin Yan | 2016 | Molecular Plant2016，9，10： | 1 |
| 8 | Sessile droplet freezing and ice adhesion on aluminum with different surface wettability and surface temperature显示文摘This paper focused on the sessile droplet freezing and ice adhesion on aluminum with different wettability(hydrophilic, common hydrophobic, and superhydrophobic surfaces, coded as HIS, CHS, SHS, respectively) over a surface temperature range of ?9°C to ?19°C. It was found that SHS could retard the sessile droplet freezing and lower the ice adhesion probably due to the interfacial air pockets(IAPs) on water/SHS interface. However, as surface temperature decreasing, some IAPs were squeezed out and such freezing retarding and adhesion lowering effect for SHS was reduced greatly. For a surface temperature of ?19°C, ice adhesion on SHS was even greater than that on CHS. To discover the reason for the squeezing out of IAPs, forces applied to the suspended water on IAPs were analyzed and it was found that the stability of IAPs was associated with surface micro-structures and surface temperature. These findings might be helpful to designing of SHS with good anti-icing properties. | OU JunFei SHI QingWen WANG ZhiLe WANG FaJun XUE MingShan LI Wen YAN GuiLong | 2015 | Science China(Physics,Mechanics & Astronomy)2015，58，7： | 1 |
| 9 | Synthetic Analogues of Betulinic Acid as Potent Inhibitors of PS1/BACE1 Interaction to Reduce Aβ Generation显示文摘lupane 类型 triterpenoids 被赋予以大量生物活动例如抗病毒,反煽动性并且 anticancer 活动。我们这里在 Alzheimers 描述它的潜在的申请疾病(广告) 治疗作为 PS1/BACE1 的一个禁止者相互作用。3-α-Akebonoic 酸,从高产量发出了屏蔽,被发现防碍 PS1/BACE1 相互作用和还原剂淀粉的 β-protein (Aβ) 生产。鉴于有限来源,当为铅优化和它的衍生物的一个集中的图书馆的开始的材料被构造获得 PS1/BACE1 相互作用的 triterpenoid 类型禁止者的结构活动关系(SAR ) 的更好的理解,我们相反使用了自然地富有的 betulinic 酸(化合物 2 ) 。化合物 22 最后被选择为大多数有势力 PS1/BACE1 相互作用禁止者,它有效地减少了 Aβ 产生。 | Chenlu Zhang Xiaoyin Wang Jin Cui Xiaohang Li Yangming Zhang Xin Wang Haifeng Gu Wei Li Xin Xie Jian Zhao Gang Pei Fajun Nan | 2017 | Chinese Journal of Chemistry2017，35，1： | 0 |
| 10 | Initial sedimentation of particles from a line source in 1-D homogenous current fields显示文摘On the basis of the study of initial sedimentation of suspended participates discharged from a continuous point source, the mode of dispersion, descension and deposition of the suspended particulates which are released from a line source is derived. By use of puff model, the semi-analytical solution to the problem of initial sedimentation of suspended particulates discharged from a continuous line source in one-dimensional homogenous current fields, of which water depth is constant, is presented, some computations and analyses for long-term distribution of sedimentation are carried out under various sets of parameters. And the comparisons between the sedimentation results of the line and point source are conducted. The results show that the higher the initial height,and the smaller the fall velocity of the particles ,the closer the sedimentation distribution results of the line source to that of the point source. | Wang Fajun Institute of Marine Environmental Protection, State Oceanic Administration, Dalian, 116023, China | 1991 | Acta Oceanologica Sinica1991，10，3： | 0 |
| 11 | Study on the Crustal Velocity Model of Xinjiang and Its Subareas显示文摘In this paper,we firstly analyze the '3,400 travel time table 'used for a long time in Xinjiang Seismological Network to obtain the velocity structure models in accord with the table by fitting. Then we fit the velocity of all seismic phases recorded in Xinjiang region in January 2009 ~ December 2013. Simulation analysis is done on the reliability and stability of the velocities,and a concept is proposed for building subarea crustal velocity models according to partitioning of seismic cluster regions. The crustal velocity model suitable for the Yutian area is fitted with the data of all phases of seismic events within a radius of 1°around the 2014 Yutian M_S7.3 earthquake since January 2009,and the model is applied to the relocation of the Yutian M_S7.3 earthquake and determination of focal depths of the earthquake sequence. | Chen Xiangjun Shangguan Wenming Song Xiuqing Wang Jun Liu Shuangqing Miao Fajun Zhu Yuanqing | 2014 | Earthquake Research in China2014，28，4： | 0 |
| 12 | Study on the Precise Location of the Xinjiang Yutian M_S7.3 Earthquake显示文摘The seismic waveform of the Yutian MS7.3 earthquake,Xinjiang on February 12,2014 was recorded clearly and completely by the Digital Seismic Networks of Xinjiang,Qinghai,Tibet,and Xinjiang Hotan array,so the method of joint location by regional seismic network and seismic array can be used to accurately determine the earthquake source location.The following technologies were used in the process of location:(1) We selected seismic stations equally located around the epicenter of the MS7.3 earthquake with an average interval of about 15 degrees in the initial location.(2) The recording waveforms of Yutian seismic station were rotated to the radial and tangential directions to precisely obtain the arrival time of S-waves to determine the epicentral distance.(3) The velocity model was used in the determination of location of the epicenter,based on the historical records of earthquakes in the area within a radius of 1.0° from the source as the center,and the velocity model is obtained after re-fitting and calibration.(4) Based on the waveform records of the Hotan seismic array,the method of waveform beaming was used to determine the azimuths and perform the correction of the epicenter location with these azimuths.(5) The deterministic method was used to measure the source depth.Finally,it is concluded that the Yutian MS7.3 main shock hypocenter location is 36.197°N,82.467°E,focal depth 12 km and original time 17:19:48.2 p.m.February 12,2014. | Zhan Xiaoyan Song Xiuqing Chen Xiangjun Wang Jun Miao Fajun Liu Shuangqing Zhu Yuanqing | 2015 | Earthquake Research in China2015，29，1： | 0 |
| 13 | Focal Depth Determination of the 2014 Yutian M_S7.3 Earthquake Sequence,Xinjiang显示文摘An M_S7.3 earthquake occurred on February 12,2014 in Yutian County,Xinjiang Uygur Autonomous Region,which was followed by a series of aftershocks. This paper calculates the depth of the M_S7.3 earthquake sequence by using the deterministic approach with the seismic phase data from the catalog database of the China Earthquake Networks Center,combined with original seismic wave records from the Digital Seismic Network Center of the Earthquake Administration of Xinjiang Uygur Autonomous Region. | Song Xiuqing Miao Fajun Liu Shuangqing Chen Xiangjun Wang Jun Zhu Yuanqing | 2014 | Earthquake Research in China2014，28，4： | 0 |
| 14 | Augmenting photoluminescence of monolayer MoS_(2) using high order modes in a metal dimer-on-film nanocavity显示文摘Plasmonic particle-on-film nanocavities,supporting gap modes with ultra-small volume,provide a great solution to boost light–matter interactions at the nanoscale.In this work,we report on the photoluminescence(PL)enhancement of monolayer MoS_(2) using high order modes of an Au nanosphere dimer-on-film nanocavity(DoFN).The high order plasmon modes,consisting of two bonding quadrupoles in the dimer and their images in the Au film,are revealed by combining the polarization-resolved scattering spectra with the numerical simulations.Further integrating the monolayer MoS_(2) into the DoFN,these high order modes are used to enhance PL intensity through simultaneously boosting the absorption and emission processes,producing a 1350-fold enhancement factor.It opens an avenue to enhance the light–matter interaction with high order plasmon modes and may find applications in future optoelectronics and nanophotonics devices. | Shiyin Cao Liping Hou Qifa Wang Chenyang Li Weixing Yu Xuetao Gan Kaihui Liu Malin Premaratne Fajun Xiao Jianlin Zhao | 2021 | Photonics Research2021，9，4： | 0 |
| 15 | Optical colorimetric LiTaO_(3)wafers for highprecision lithography on frequency control of SAW devices显示文摘Surface acoustic wave(SAW)resonators based on lithium tantalate(LT,LiTaO_(3))wafers are crucial elements of mobile communication filters.The use of intrinsic LT wafers typically brings about low fabrication accuracy of SAW resonators due to strong UV reflection in the lithography process.This hinders their resonance frequency control seriously in industrial manufacture.LT doping and chemical reduction could be applied to decrease the UV reflection of LT wafers for high lithographic precision.However,conventional methods fail to provide a fast and nondestructive approach to identify the UV performance of standard single-side polished LT wafers for highprecision frequency control.Here,we propose a convenient on-line sensing scheme based on the colorimetry of reduced Fe-doped LT wafers and build up an automatic testing system for industrial applications.The levels of Fe doping and chemical reduction are evaluated by the lightness and color difference of LT-based wafers.The correlation between the wafer visible colorimetry and UV reflection is established to refine the lithography process and specifically manipulate the frequency performance of SAW resonators.Our study provides a powerful tool for the fabrication control of SAW resonators and will inspire more applications on sophisticated devices of mobile communication. | MING HUI FANG YINONG XIE FANGQI XUE ZHILIN WU JUN SHI SHENG YU YANG YILIN LIU ZHIHUANG LIU HSIN CHI WANG FAJUN LI QING HUO LIU JINFENG ZHU | 2024 | Photonics Research2024，12，2： | 0 |
| 16 | Status epilepticus increases mature granule cells in the molecular layer of the dentate gyrus in rats显示文摘Enhanced neurogenesis in the dentate gyrus of the hippocampus following seizure activity, especially status epilepticus, is associated with ectopic residence and aberrant integration of newborn granule cells. Hilar ectopic granule cells may be detrimental to the stability of dentate circuitry by means of their electrophysiological properties and synaptic connectivity. We hypothesized that status epilepticus also increases ectopic granule cells in the molecular layer. Status epilepticus was induced in male Sprague-Dawley rats by intraperitoneal injection of pilocarpine. Immunostaining showed that many doublecortin-positive cells were present in the molecular layer and the hilus 7 days after the induction of status epilepticus. At least 10 weeks after status epilepticus, the estimated number of cells positive for both prospero homeobox protein 1 and neuron-specific nuclear protein in the hilus was significantly increased. A similar trend was also found in the molecular layer. These findings indicate that status epilepticus can increase the numbers of mature and ectopic newborn granule cells in the molecular layer. | Zhaoliang Liang Fei Gao Fajun Wang Xiaochen Wang Xinyu Song Kejing Liu Ren-Zhi Zhan | 2013 | Neural Regeneration Research2013，8，7： | 0 |
| 17 | In situ growth of NiSe_(2) nanocrystalline array on graphene for efficient hydrogen evolution reaction显示文摘Nickel selenide electrocatalysts for hydrogen evolution reaction(HER)with a high efficiency and a lowcost have a significant potential in the development of water splitting.However,the inferiority of the high overpotential and poor stability restricts their practical applications.Herein,a composite nanostructure consists of ultrasmall NiSe_(2) nanocrystals embedded on graphene by microwave reaction is reported.The prepared NiSe_(2)/reduced graphite oxide(rGO)electrocatalyst exhibited a high HER activity with an overpotential of 158 mV at a current density of 10 mA/cm^(2) and a corresponding moderate Tafel slope of 56 mV/dec in alkaline electrolyte.In addition,a high retention of electrochemical properties(approximately 100%)was demonstrated with an unchangeable microstructure after 100 h of continuous operation. | Shuai JI Changgan LAI Huan ZHOU Helin WANG Ling MA Cong WANG Keying ZHANG Fajun LI Lixu LEI | 2022 | Frontiers in Energy2022，16，4： | 0 |
| 18 | Construction of the Hexacyclic Core of Dispirocochlearoids A-C via a Diels-Alder Reaction显示文摘The natural products of dispirocochlearoids are complex Ganoderma meroterpenoids featuring a 6/6/5/6/6/6 ring system and are selective cox-2 inhibitors.Herein,we describe our progress regarding the total synthesis of dispirocochlearoids A-C,in which a hexacyclic skeleton was constructed firstly.The key steps of this work involve an intermolecular[4+2]cycloaddition reaction,a ring cleavage approach via Ticla,and the installation of a profoundly sterically hindering lactone. | Qiang Fu Yonghui Wang Fajun Nan | 2022 | Chinese Journal of Chemistry2022，40，13： | 0 |
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