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| 1 | Synthesis of ordered mesoporous carbonaceous materials and their highly efficient capture of uranium from solutions显示文摘An extremely effortless method was applied for successful synthesis of mesoporous carbonaceous materials(MCMs) using well-ordered mesoporous silica as template. Various characterizations(scanning electron microscopy(SEM), transmission electron microscopy(TEM), X-ray diffraction(XRD), Fourier transform infrared spectroscopy(FT-IR), Raman, X-ray photoelectron spectroscopy(XPS), Brunner-Emmet-Teller(BET) and Zeta potential) confirmed that MCMs had large surface area, uniform pore size distribution, and abundant oxygen-containing functional groups. The batch techniques were employed to study U(VI) adsorption on MCMs under a wide range of experiment conditions. The adsorption kinetics of U(VI) onto MCMs were well-fitted by pseudo-second-order kinetic model, indicating a chemisorption process. The excellent adsorption capacity of MCMs calculated from the Langmuir model was 293.95 mg g^(-1) at pH 4.0. The FT-IR and XPS analyses further evidenced that the binding of U(VI) onto MCMs was ascribed to the plentiful adsorption sites(–OH and –COOH groups) in the internal mesoporous structure, which could efficiently trap guest U(VI) ions. The results presented herein revealed that MCMs were ideal adsorbents in the efficient elimination of uranium or other lanthanides/actinides from aqueous solutions, which would play an important role in environmental pollution management application. | Chenlu Zhang Xing Li Zhongshan Chen Tao Wen Shuyi Huang Tasawar Hayat Ahmed Alsaedi Xiangke Wang | 2018 | Science China Chemistry2018，61，3： | 8 |
| 2 | Interactive effects of understory removal and fertilization on soil respiration in subtropical Eucalyptus plantations显示文摘Aims It has been well recognized that understory vegetation plays an important role in driving forest ecosystem processes and functioning.In subtropical plantation forests,understory removal and fertiliza-tion have been widely applied;however,our understanding on how understory removal affects soil respiration and how the process is regulated by fertilization is limited.Here,we conducted an under-story removal experiment combined with fertilization to evaluate the effects of the two forest management practices and their inter-actions on soil respiration in subtropical forest in southern China.Methods The study was conducted in a split-plot design with fertilization as the whole-plot factor,understory removal as the subplot factor and block as the random factor in subtropical Eucalyptus plantations.In total,there were four treatments:control with unfertilized and intact understory(CK),understory removal but without fertilization(UR),with fertilization but without understory removal(FT)and with fertilization+understory removal(FT+UR).Eucalyptus above-and belowground biomass increment,fine root biomass,soil tempera-ture,soil moisture and soil respiration were measured in the present study.understory respiration(Ru)was quantified in different ways:Ru=RCK−Ru or Ru=RFT−R(FT+u);fertilization increased soil respiration(RFI)was also quantified in different ways:RFI=RFT−RCK or RFI=R(FT+u)−Ru.Important Findingsover a 2-year experiment,our data indicate that understory removal significantly decreased soil respiration,while fertilization increased soil respiration.understory removal decreased soil respiration by 28.8%under fertilization,but only 15.2%without fertilization.Fertilization significantly increased soil respiration by 23.6%with the presence of understory vegetation,and only increased by 3.7%when understory was removed,indicating that fertilization increased soil respiration mainly by increasing the contribution of the understory.our study advances our understanding of the interactive effects of understory management and fertilization on soil respiration in subtropical plantations. | Songze Wan Chenlu Zhang Yuanqi Chen Jie Zhao Xiaolin Zhu Jianping Wu Lixia Zhou Yongbiao Lin Zhanfeng Liu Shenglei Fu | 2015 | Journal of Plant Ecology2015，8，3： | 6 |
| 3 | Toward emerging gallium oxide semiconductors:A roadmap显示文摘Owing to the advantages of ultra-wide bandgap and rich material systems,gallium oxide(Ga_(2)O_(3))has emerged as a highly viable semiconductor material for new researches.This article mainly focuses on the growth processes,material characteristics,and applications of Ga_(2)O_(3).Compared with single crystals and the epitaxial growth of other wide-bandgap semiconductors,large-size and high-quality��-Ga_(2)O_(3) single crystals can be efficiently grown with a low cost,making them highly competitive.Thanks to the availability of high-quality single crystals,epi-taxial films,and rich material systems,high-performance semiconductor devices based on Ga_(2)O_(3) go through a booming development in recent years.The defects and interfaces of Ga_(2)O_(3) are comprehensively analyzed owing to their significant influence on practical applications.In this study,the two most common applications of Ga_(2)O_(3) materials are introduced.The high breakdown electric field,high working temperature,and excellent Baliga’s figure-of-merit of Ga_(2)O_(3) represent an inspiring prospect for power electronic devices.In addition,the excellent absorption in deep-ultraviolet band provides new ideas for optoelectronic detectors and ensures the dramatic progress.Finally,the summary,challenges,and prospects of the Ga_(2)O_(3) materials and devices are presented and discussed. | Yuan Yuan Weibing Hao Wenxiang Mu Zhengpeng Wang Xuanhu Chen Qi Liu Guangwei Xu Chenlu Wang Hong Zhou Yanni Zou Xiaolong Zhao Zhitai Jia Jiandong Ye Jincheng Zhang Shibing Long Xutang Tao Rong Zhang Yue Hao | 2021 | Fundamental Research2021，1，6： | 5 |
| 4 | Temperature-induced Lifshitz transition in topological insulator candidate HfTe_5显示文摘The ongoing discoveries and studies of novel topological quantum materials have become an emergent and important field of condensed matter physics.Recently,HfTe_5 ignited renewed interest as a candidate of a novel topological material.The single-layer HfTe_5 is predicted to be a two-dimensional large band gap topological insulator and can be stacked into a bulk that may host a temperature-driven topological phase transition.Historically,HfTe_5 attracted considerable interest for its anomalous transport properties characterized by a peculiar resistivity peak accompanied by a sign reversal carrier type.The origin of the transport anomaly remains under a hot debate.Here we report the first high-resolution laser-based angle-resolved photoemission measurements on the temperature-dependent electronic structure in HfTe_5.Our results indicated that a temperature-induced Lifshitz transition occurs in HfTe_5,which provides a natural understanding on the origin of the transport anomaly in HfTe_5.In addition,our observations suggest that HfTe_5 is a weak topological insulator that is located at the phase boundary between weak and strong topological insulators at very low temperature. | Yan Zhang Chenlu Wang Guodong Liu Aiji Liang Lingxiao Zhao Jianwei Huang Qiang Gao Bing Shen Jing Liu Cheng Hu Wenjuan Zhao Genfu Chen Xiaowen Jia Li Yu Lin Zhao Shaolong He Fengfeng Zhang Shenjin Zhang Feng Yang Zhimin Wang Qinjun Peng Zuyan Xu Chuangtian Chen Xingjiang Zhou | 2017 | Science Bulletin2017，62，13： | 4 |
| 5 | Cytosolic delivery of the immunological adjuvant PolyⅠ:C and cytotoxic drug crystals via a carrier-free strategy significantly amplifies immune response显示文摘Co-delivery of chemotherapeutics and immunostimulant or chemoimmunotherapy is an emerging strategy in cancer therapy.The precise control of the targeting and release of agents is critical in this methodology.This article proposes the asynchronous release of the chemotherapeutic agents and immunostimulants to realize the synergistic effect between chemotherapy and immunotherapy.To obtain a proof-of-concept,a co-delivery system was prepared via a drug-delivering-drug(DDD)strategy for cytosolic co-delivery of Poly I:C,a synthetic ds RNA analog to activate RIG-I signaling,and PTX,a commonly used chemotherapeutics,in which pure PTX nanorods were sequentially coated with Poly I:C and mannuronic acid via stimulating the RIG-I signaling axis.The co-delivery system with a diameter of 200 nm enables profound immunogenicity of cancer cells,exhibiting increased secretion of cytokines and chemokines,pronounced immune response in vivo,and significant inhibition of tumor growth.Also,we found that intracellularly sustained release of cytotoxic agents could elicit the immunogenicity of cancer cells.Overall,the intracellular asynchronous release of chemotherapeutics and immunomodulators is a promising strategy to promote the immunogenicity of cancer cells and augment the antitumor immune response. | Xiaoqing Du Yuqi Hou Jia Huang Yan Pang Chenlu Ruan Wei Wu Chenjie Xu Hongwei Zhang Lifang Yin Wei He | 2021 | Acta Pharmaceutica Sinica B2021，11，10： | 3 |
| 6 | High CO_(2) absorption capacity of metal-based ionic liquids: A molecular dynamics study显示文摘The absorption of CO_(2)is of importance in carbon capture,utilization,and storage technology for greenhouse gas control.In the present work,we clarified the mechanism of how metal-based ionic liquids (MBILs),Bmim[XCl_(n)]_(m)(X is the metal atom),enhance the CO_(2)absorption capacity of ILs via performing molecular dynamics simulations.The sparse hydrogen bond interaction network constructed by CO_(2)and MBILs was identified through the radial distribution function and interaction energy of CO_(2)-ion pairs,which increase the absorption capacity of CO_(2)in MBILs.Then,the dynamical properties including residence time and self-diffusion coefficient confirmed that MBILs could also promote the diffusion process of CO_(2)in ILs.That's to say,the MBILs can enhance the CO_(2)absorption capacity and the diffusive ability simultaneously.Based on the analysis of structural,energetic and dynamical properties,the CO_(2)absorption capacity of MBILs increases in the order Cl^-→[ZnCl_(4)]^(2-)→[CuCl_(4)]^(2-)→[CrCl_(4)]^-→[FeCl_(4)]^-,revealing the fact that the short metal–Cl bond length and small anion volume could facilitate the performance of CO_(2)absorbing process.These findings show that the metal–Cl bond length and effective volume of the anion can be the effective factors to regulate the CO_(2)absorption process,which can also shed light on the rational molecular design of MBILs for CO_(2)capture and other key chemical engineering processes,such as IL-based gas sensors,nano-electrical devices and so on. | Biwen Li Chenlu Wang Yaqin Zhang Yanlei Wang | 2021 | Green Energy & Environment2021，6，2： | 3 |
| 7 | Considerable impacts of litter inputs on soil nematode community composition in a young Acacia crassicapa plantation显示文摘Aboveground litter inputs and root exudates provide basal resources for soil communities,however,their relative contributions to soil food web are still not well understood.Here,we conducted a field manipulative experiment to differentiate the effects of litter inputs and living root on nematode community composition of surface and subsoils in a young Acacia crassicapa plantation in southern China.Our results showed that both litter addition and root presence significantly enhanced soil nematode abundance by 17.3%and 35.3%,respectively.Litter addition altered nematode trophic group composition,decreased fungivore to bacterivore ratio,and enhanced maturity index and structure index,which led to a bacterial-based energy channel and a more complex food web structure.However,root presence had a limited impact on the nematode community composition and ecological indices.Despite nematodes surface assembly,soil depth did not affect nematode trophic group composition or ecological index.Our findings highlight the importance of litter inputs in shaping soil nematode community structure and regulating soil energy channel. | CANCAN ZHAO YIN LI CHENLU ZHANG Yuan Miao Mengzhou Liu Wanlin Zhuang Yuanhu Shao Weixin Zhang Shenglei Fu | 2021 | Soil Ecology Letters2021，3，2： | 2 |
| 8 | HSP70 alleviates sepsis-induced cardiomyopathy by attenuating mitochondrial dysfunction-initiated NLRP3 inflammasome-mediated pyroptosis in cardiomyocytes显示文摘Background:Sepsis-induced cardiomyopathy(SIC)is an identified serious complication of sepsis that is associated with adverse outcomes and high mortality.Heat shock proteins(HSPs)have been implicated in suppressing septic inflammation.The aim of this study was to investigate whether HSP70 can attenuate cellular mitochondrial dysfunction,exuberated inflammation and inflammasome-mediated pyroptosis for SIC intervention.Methods:Mice with cecal ligation plus perforation(CLP)and lipopolysaccharide(LPS)-treated H9C2 cardiomyocytes were used as models of SIC.The mouse survival rate,gross profile,cardiac function,pathological changes and mitochondrial function were observed by photography,echocardiography,hematoxylin-eosin staining and transmission electron microscopy.In addition,cell proliferation and the levels of cardiac troponin I(cTnI),interleukin-1β(IL-1β)and tumor necrosis factor-α(TNF-α)were determined by Cell Counting Kit-8,crystal violet staining and enzyme-linked immunosorbent assay.Moreover,mitochondrial membrane potential was assessed by immunofluorescence staining,and dynamin-related protein 1 and pyroptosis-related molecules[nucleotide-binding domain,leucine-rich-repeat containing family pyrin domain-containing 3(NLRP3),caspase-1,gasdermin-D(GSDMD),gasdermin-D N-terminal(GSDMD-N)]were measured by western blotting,immunoprecipitation and immunoblotting.Finally,hsp70.1 knockout mice with CLP were used to verify the effects of HSP70 on SIC and the underlying mechanism.Results:Models of SIC were successfully established,as reduced consciousness and activity with liparotrichia in CLP mice were observed,and the survival rate and cardiac ejection fraction(EF)were decreased;conversely,the levels of cTnI,TNF-αand IL-1βand myocardial tissue damage were increased in CLP mice.In addition,LPS stimulation resulted in a reduction in cell viability,mitochondrial destabilization and activation of NLRP3-mediated pyroptosis molecules in vitro.HSP70 treatment improved myocardial tissue damage,survival rate and cardiac dysfunction caused by CLP.Additionally,HSP70 intervention reversed LPS-induced mitochondrial destabiliza-tion,inhibited activation of the NLRP3 inflammasome,caspase-1,GSDMD and GSDMD-N,and decreased pyroptosis.Finally,knockout of hsp70.1 mice with CLP aggravated cardiac dysfunction and upregulated NLRP3 inflammasome activity,and exogenous HSP70 significantly rescued these changes.It was further confirmed that HSP70 plays a protective role in SIC by attenuating mitochondrial dysfunction and inactivating pyroptotic molecules.Conclusions:Our study demonstrated that mitochondrial destabilization and NLRP3 inflammasome activation-mediated pyroptosis are attributed to SIC.Interestingly,HSP70 ameliorates sepsis-induced myocardial dysfunction by improving mitochondrial dysfunction and inhibiting the acti-vation of NLRP3 inflammasome-mediated pyroptosis,and such a result may provide approaches for novel therapies for SIC. | Chenlu Song Yiqiu Zhang Qing Pei Li Zheng Meiyu Wang Youzhen Shi Shan Wu Wei Ni Xiujun Fu Yinbo Peng Wen Zhang Min Yao | 2022 | Burns & Trauma2022，10，1： | 2 |
| 9 | Visualizing DC morphology and T cell motility to characterize DC-T cell encounters in mouse lymph nodes under mTOR inhibition显示文摘Mammalian target of rapamycin(mTOR),a serine/threonine kinase orchestrating cellular metabolism,is a crucial immune system regulator.However,it remains unclear how mTOR regulates dendritic cell(DC) function in vivo,especially DC-T cell encounters,a critical step for initiating adaptive immune responses.We dynamically visualized DC-T contacts in mouse lymph node using confocal microscopy and established an encounter model to characterize the effect of mTOR inhibition on DC-T cell encounters using DC morphology.Quantitative data showed mTOR inhibition via rapamycin altered DC shape,with an increased form factor(30.17%) and decreased cellular surface area(20.36%) and perimeter(22.43%),which were associated with Cdc42 protein downregulation(52.71%).Additionally,DCs adopted a similar morphological change with Cdc42 inhibition via ZCL278 as that observed with mTOR inhibition.These morphologically altered DCs displayed low encounter rates with T cells.Time-lapse imaging data of T cell motility supported the simulated result of the encounter model,where antigen-specific T cells appeared to reduce arrest in the lymph nodes of rapamycin-pretreated mice relative to the untreated group.Therefore,mTOR inhibition altered DC morphology in vivo and decreased the DC-T cell encounter rate,as well as Cdc42 inhibition.By establishing an encounter model,our study provides an intuitive approach for the early prediction of DC function through morphological quantification of form factor and area. | Qiaoya Lin Zheng Liu Meijie Luo Hao Zheng Sha Qiao Chenlu Han Deqiang Deng Zhan Fan Yafang Lu Zhihong Zhang Qingming Luo | 2019 | Science China(Life Sciences)2019，62，9： | 2 |
| 10 | Daily power demand prediction for buildings at a large scale using a hybrid of physics-based model and generative adversarial network显示文摘Power demand prediction for buildings at a large scale is required for power grid operation.The bottom-up prediction method using physics-based models is popular,but has some limitations such as a heavy workload on model creation and long computing time.Top-down methods based on data driven models are fast,but less accurate.Considering the similarity of power demand patterns of single buildings and the superiority of generative adversarial network(GAN),this paper proposes a new method(E-GAN),which combines a physics-based model(EnergyPlus)and a data-driven model(GAN),to predict the daily power demand for buildings at a large scale.The new E-GAN method selects a small number of typical buildings and utilizes EnergyPlus models to predict their power demands.Utilizing the prediction for those typical buildings,the GAN then is adopted to forecast the power demands of a large number of buildings.To verify the proposed method,the E-GAN is used to predict 24-hour power demands for a set of residential buildings.The results show that(1)4.3%of physics-based models in each building category are required to ensure the prediction accuracy;(2)compared with the physics-based model,the E-GAN can predict power demand accurately with only 5%error(measured by mean absolute percentage error,MAPE)while using only approximately 9%of the computing time;and(3)compared with data-driven models(e.g.,support vector regression,extreme learning machine,and polynomial regression model),E-GAN demonstrates at least 60%reduction in prediction error measured by MAPE. | Chenlu Tian Yunyang Ye Yingli Lou Wangda Zuo Guiqing Zhang Chengdong Li | 2022 | Building Simulation2022，15，9： | 2 |
| 11 | Toripalimab in advanced biliary tract cancer显示文摘Gemcitabine combined with platinum/fluorouracil drugs is the standard firstline treatment for advanced biliary tract cancers(BTCs).We explored the safety and efficacy of toripalimab plus gemcitabine and S-1(GS)as the first-line treatment for advanced BTCs.At a one-sided significance level of 0.025,a total of 50 patients could provide 80%power to show the efficacy at targeted progression-free survival(PFS)rate at 6 months of 70%versus 40%for the combined treatment.This single-arm,phase II study enrolled 50 patients with advanced BTCs who previously received no systemic treatment.The regimen was as follows:toripalimab(240 mg,i.v.,d1),gemcitabine(1,000 mg/m2,i.v.,d1 and d8),and S-1(40–60 mg bid p.o.,d1–14,Q21d).The primary endpoint was progression-free survival.The secondary endpoints included overall survival(OS),objective response rate(ORR),duration of response(DOR),and safety.The associations between response with PDL1 expression,tumor mutational burden(TMB),and genetic variations were explored.Patients were enrolled from January 2019 to August 2020,with a median follow-up time of 24.0 months(IQR:4.3–31.0 months). | Wei Li Yueqi Wang Yiyi Yu Qian Li Yan Wang Chenlu Zhang Xiaojing Xu Xi Guo Yu Dong Yuehong Cui Qing Hao Lujia Huang Houbao Liu Tianshu Liu | 2022 | The Innovation2022，3，4： | 1 |
| 12 | Ufl1 deficiency causes kidney atrophy associated with disruption of endoplasmic reticulum homeostasis显示文摘The UFMylation modification is a novel ubiquitin-like conjugation system,consisting of UBA5(E1),UFC1(E2),UFL1(E3),and the conjugating molecule UFM1.Deficiency in this modification leads to embryonic lethality in mice and diseases in humans.However,the function of UFL1 is poorly characterized.Studies on Ufl1 conditional knockout mice have demonstrated that the deletion of Ufl1 in cardiomyocytes and in intestinal epithelial cells causes heart failure and increases susceptibility to experimentally induced colitis,respectively,suggesting an essential role of UFL1 in the maintenance of the homeostasis in these organs.Yet,its physiological function in other tissues and organs remains completely unknown.In this study,we generate the nephron tubules specific Ufl1 knockout mice and find that the absence of Ufl1 in renal tubular results in kidney atrophy and interstitial fibrosis.In addition,Ufl1 deficiency causes the activation of unfolded protein response and cell apoptosis,which may be responsible for the kidney atrophy and interstitial fibrosis.Collectively,our results have demonstrated the crucial role of UFL1 in regulating kidney function and maintenance of endoplasmic reticulum homeostasis,providing another layer of understanding kidney atrophy. | You Zhou Xifu Ye Chenlu Zhang Jiabao Wang Zeyuan Guan Juzhen Yan Lu Xu Ke Wang Di Guan Qian Liang Jian Mao Junzhi Zhou Qian Zhang Xiaoying Wu Miao Wang Yu-Sheng Cong Jiang Liu | 2021 | Journal of Genetics and Genomics2021，48，5： | 1 |
| 13 | Characteristics and source apportionment of PM_(2.5) under the dual influence of the Spring Festival and the COVID-19 pandemic in Yuncheng city显示文摘Based on the online and membrane sampling data of Yuncheng from January 1st to February 12th,2020,the formation mechanism of haze under the dual influence of Spring Festival and COVID-19 (Corona Virus Disease) was analyzed.Atmospheric capacity,chemical composition,secondary transformation,source apportionment,backward trajectory,pollution space and enterprise distribution were studied.Low wind speed,high humidity and small atmospheric capacity inhibited the diffusion of air pollutants.Four severe pollution processes occurred during the period,and the pollution degree was the highest around the Spring Festival.In light,medium and heavy pollution periods,the proportion of SNA (SO_(4)^(2-),NO_(3)-and NH_(4)^(+)) was 59.6%,56.0%and 54.9%,respectively,which was the largest components of PM_(2.5);the[NO_(3)-]/[SO_(4)^(2-)]ratio was 2.1,1.5 and 1.7,respectively,indicating that coal source had a great influence;the changes of NOR (nitrogen oxidation ratio,0.44,0.45,0.61)and SOR (sulphur oxidation ratio,0.40,0.49,0.65) indicated the accumulation of secondary aerosols with increasing pollution.The coal combustion,motor vehicle,secondary inorganic sources and industrial sources contributed 36.8%,26.59%,11.84%and 8.02%to PM_(2.5)masses,respectively.Backward trajectory showed that the influence from the east was greater during the Spring Festival,and the pollutants from the eastern air mass were higher,which would aggravate the pollution.Meteorological and Spring Festival had a great impact on heavy pollution weather.Although some work could not operate due to the impact of the COVID-19 epidemic,the emission of pollutants did not reduce much. | Chen Zhang Yingying Zhang Xingang Liu Yafei Liu Chenlu Li | 2023 | Journal of Environmental Sciences2023，，3： | 1 |
| 14 | Lubricating properties of ester oil prepared from bio-based 2,5-furandicarboxylic acid显示文摘The depletion of petroleum resources and the intensification of environmental problems have necessitated the development of renewable products from bio-based chemicals instead of petroleum resources.Herein,a new kind of ester lubricating oil,isooctyl furan dicarboxylate(isooctyl-FD),was prepared from bio-based 2,5-furandicarboxylic acid.The structure of isooctyl-FD was evaluated using nuclear magnetic resonance imaging and high-resolution mass spectroscopy.Its physicochemical and tribological properties including thermal and oxidation stabilities,flash point and pour point,viscosity and viscosity index,and friction-reducing and anti-wear properties were systematically evaluated.The results show that isooctyl-FD has comparable thermal and oxidation stability to the synthetic ester lubricating oil,isooctyl sebacate(isooctyl-S).Its friction-reducing and anti-wear properties are superior to isooctyl-S;however,its viscosity-temperature and low-temperature properties are inferior to isooctyl-S. | Mingjin FAN Jia Al Shuai ZHANG Chenlu YANG Xin DU Ping WEN Xiangyuan YE Feng ZHOU Weiming LIU | 2020 | Friction2020，8，2： | 1 |
| 15 | LHRH/TAT dual peptides-conjugated polymeric vesicles for PTT enhanced chemotherapy to overcome hepatocellular carcinoma显示文摘Combination therapy such as photothermal therapy(PTT)enhanced chemotherapy is regarded as a promising strategy for cancer treatment.Herein,we developed redox-responsive polymeric vesicles based on the amphiphilic triblock copolymer PCL-ss-PEG-ss-PCL.To avoid the limited therapeutic effect of chemotherapeutic drugs caused by systemic exposures and drug resistance,the redox-sensitive polymeric vesicles were cargoed with two chemotherapeutics:doxorubicin(DOX)and paclitaxel(PTX).Besides,indocyanine green(ICG)was encapsulated,and cell-penetrating peptides and LHRH targeting molecule were modified on the surface of polymeric vesicles.The results indicated that the polymeric vesicles can load different kinds of drugs with high drug loading content,trigger drug release in responsive to the reductive environment,realize high cellular uptake via dual peptides and laser irradiation,and achieve higher cytotoxicity via chemo-photothermal combination therapy.Hence,the redox-responsive LHRH/TAT dual peptides-conjugated PTX/DOX/ICG co-loaded polymeric micelles exhibited great potential in tumor-targeting and chemo-photothermal therapy. | Yu Qin Qing Guo Shengjie Wu Chenlu Huang Zhiming Zhang Li Zhang Linhua Zhang Dunwan Zhu | 2020 | Chinese Chemical Letters2020，31，12： | 1 |
| 16 | Contributions of understory and/or overstory vegetations to soil microbial PLFA and nematode diversities in Eucalyptus monocultures 显示文摘 | ZHAO Jie WAN Songze ZHANG Chenlu | 2014 | PLOS One2014，9，85： | 1 |
| 17 | Contributions of understory and/or overstory vegetations to soil microbial PLFA and nematode diversities in Eucalyptus monocuhures 显示文摘 | ZHAO Jie WAN Songze ZHANG Chenlu | 2014 | PLOS One2014，9，85： | 1 |
| 18 | Ambidextrous organizational learning, environmental munificence and new product performance: Moderating effect of managerial ties in China显示文摘 | Yuan Li Zelong Wei Jie Zhao Chenlu Zhang Yi Liu | 2012 | International Journal of Production Economics2012，，： | 1 |
| 19 | Synthetic Analogues of Betulinic Acid as Potent Inhibitors of PS1/BACE1 Interaction to Reduce Aβ Generation显示文摘lupane 类型 triterpenoids 被赋予以大量生物活动例如抗病毒,反煽动性并且 anticancer 活动。我们这里在 Alzheimers 描述它的潜在的申请疾病(广告) 治疗作为 PS1/BACE1 的一个禁止者相互作用。3-α-Akebonoic 酸,从高产量发出了屏蔽,被发现防碍 PS1/BACE1 相互作用和还原剂淀粉的 β-protein (Aβ) 生产。鉴于有限来源,当为铅优化和它的衍生物的一个集中的图书馆的开始的材料被构造获得 PS1/BACE1 相互作用的 triterpenoid 类型禁止者的结构活动关系(SAR ) 的更好的理解,我们相反使用了自然地富有的 betulinic 酸(化合物 2 ) 。化合物 22 最后被选择为大多数有势力 PS1/BACE1 相互作用禁止者,它有效地减少了 Aβ 产生。 | Chenlu Zhang Xiaoyin Wang Jin Cui Xiaohang Li Yangming Zhang Xin Wang Haifeng Gu Wei Li Xin Xie Jian Zhao Gang Pei Fajun Nan | 2017 | Chinese Journal of Chemistry2017，35，1： | 0 |
| 20 | Sonochemical synthesis of silver nanoparticles coated copper wire for low-temperature solid state bonding on silicon substrate显示文摘Silver nanoparticles (AgNPs) are directly grown on surface of ~25 μm copper wire by ultrasound-assisted chemical reduction. Silver nitrate is used as precursors, when polyvinylpyrrolidone (PVP) is added as a controller of the dimension of AgNPs. Influence of growth parameters such as precursor's concentration, ratio proportion of PVP and ultra-sonication on the growth of AgNPs coating are determined. The best morphology, size of the AgNPs are observed on copper wire. The results show that the copper wire coated with AgNPs of^100 nm diameter exhibits good antioxidation and ohmic contact after sinter on Si substrate at a temperature as low as 320℃, is especially suitable as a substitute for silver paste electrode used in silicon solar cells. | Qiang Hu Chen Zhao Zhejuan Zhang Jun Guo Chenlu Yu Zhuo Sun Xianqing Piao | 2019 | Chinese Chemical Letters2019，30，7： | 0 |
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