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| 1 | Cervical Cancer Screening Rates Among Chinese Women—China,2015显示文摘What is already known about this topic?Cervical cancer is the fourth most common cancer of women around the world.Age-adjusted incidence and mortality rates of cervical cancer were 11.78 and 3.29 per 100,000,respectively,in China in 2015.What is added by this report?Cervical cancer screening rates were 25.7%for women aged 20–64 years old and 31.4%for women aged 35–64 years old in China in 2015.Screening rates were lower in rural areas than in urban areas and varied across provinces.What are the implications for public health practice?Efforts should be made to continue to strengthen national and local policy initiatives,financial support,health education,and accessibility to women in rural areas for cervical cancer screening coverage. | Mei Zhang Yijing Zhong Zhenping Zhao Zhengjing Huang Xiao Zhang Chun Li Maigeng Zhou Jing Wu Limin Wang Xiaoying Zheng Linhong Wang | 2020 | China CDC weekly2020，2，26： | 17 |
| 2 | 1990—2017年中国伤害负担:2017年全球疾病负担研究结果(摘译)显示文摘伤害是全球性的公共卫生挑战,涉及各年龄组和不同性别的人群。过去三十年来,中国经济快速发展,人口老龄化趋势加重,社会呈现出城镇化、机动化和老龄化等特征。随着人们生活环境和生活方式的改变,伤害已跃居人群致死原因第五位,仅排在恶性肿瘤、心脑血管疾病、呼吸系统疾病和心肌梗死之后。据估计,中国每年在伤害方面消耗的直接医疗费用约为650亿元人民币. | 林泽婷(译) 吕来文(译) 黄晓晴(译) 李丽萍(审校) Duan Leilei Ye Pengpeng Juanita A Haagsma Jin Ye Wang Yuan Er Yuliang Deng Xiao Gao Xin Ji Cuirong Wang Linhong Marlena S Bannick W Cli Mountjoy-Venning Caitlin N Hawley Zichen Liu Mari Smith Spencer L James Theo Vos Christopher J L Murray | 2020 | 伤害医学(电子版)2020，9，2： | 15 |
| 3 | Cervical Cancer Screening Coverage — China, 2018–2019显示文摘What is already known about this topic?The World Health Organization set a 2030 target of 70%cervical cancer screening coverage for women aged 35–45 years.Coverage stood at 37%in China in 2015.What is added by this report?In 2018–2019,China’s cervical cancer screening coverage reached 43.4%in women aged 35–44 years and 36.8%in women aged 35–64 years.Screening coverage was still lower in rural areas as well as central and western regions;large variations existed across provincial-level administrative divisions.What are the implications for public health practice?National and local policy and financial support should be maintained for cervical cancer screening,along with more targeted health education and outreach efforts and strengthened accessibility of health services in the rural areas and central and western regions. | Mei Zhang Yijing Zhong Limin Wang Heling Bao Zhengjing Huang Zhenping Zhao Xiao Zhang Chun Li Kelly Liang Sun Jing Wu Xiaoying Zheng Linhong Wang | 2022 | China CDC weekly2022，4，48： | 11 |
| 4 | Breast Cancer Screening Rates Among Women Aged 20 Years and Above—China,2015显示文摘What is already known about this topic?Breast cancer is the most common cancer in women in China and around the world.By 2019,121 countries have instituted a national screening program as a secondary prevention measure for breast cancer.What is added by this report?Breast cancer screening rates in China were 18.9%in women aged 20 years and above,and 25.7%in women aged 35-64 years in 2015.The screening rate for women aged 20 years and above was significantly higher in urban areas than in rural areas(24.6%vs.15.0%),and in the eastern region than in the central and western regions(24.0%vs.15.1%and 15.3%). | Mei Zhang Yijing Zhong Heling Bao Zhenping Zhao Zhengjing Huang Xiao Zhang Chun Li Maigeng Zhou Limin Wang Jing Wu Xiaoying Zheng Linhong Wang | 2021 | China CDC weekly2021，3，13： | 5 |
| 5 | Sulfoalkyl ether β-cyclodextrin derivatives synthesized by a single step method as pharmaceutical biomaterials显示文摘We report a simple 'one pot' single step method to synthesize sulfoalkyl ether β-cyclodextrin (β-CD) derivatives in aqueous solution, which avoids the limitations associated with commonly used organic synthesis of such derivatives including multi-step reactions, use of expensive, toxic, and often environmentally hazardous organic solvents and/or reagents. Using this method, we obtained sulfopropyl and sulfobutyl ethyl β-CDs. We characterized these two derivatives and evaluated their ability to enhance solubility of fluconazole, a commonly used antifungal drug with poor water solubility. Experimental results indicate that these derivatives are structurally analogous to some of the commercially available β-CD derivatives. More importantly, when they formed supramolecular inclusion complexes with fluconazole, they demonstrated similar, if not better, capacity to enhance fluconazole solubility compared with commercially available β-CD derivatives, suggesting that the simple 'one pot' single step synthesis may provide an effective alternative approach to produce large quantity of β-CD derivatives as pharmaceutical biomaterials for medicinal applications. | SONG AiJing WANG JianHua LIU ChunDong DENG LinHong | 2009 | Chinese Science Bulletin2009，54，18： | 4 |
| 6 | Post-marketing safety surveillance and reevaluation of Motherwort injection:A clinical study of 10094 cases显示文摘OBJECTIVE:To investigate the safety profiles of Motherwort injection(MI).METHODS:A multi-center,prospective and drugderived hospital intensive monitoring method was conducted to assess the safety of MI in real world applications.This study was based on a very large population after the injection was approved and marketed in China.All patients using the injection in participating hospitals were monitored to determine the incidence,pattern,severity and outcome of associated adverse events.RESULTS:The post-marketing surveillance was performed in 10 094 female patients from April to December,2015.The incidence of adverse drug reactions(ADRs) was 0.79‰(8/10 094).Among the 8 patients,the reported adverse events mainly included systemic abnormalities,such as fever,chills and eyelid edema;skin and appendages disorders,such as pruritus and rash;gastrointestinal disorders,such as nausea,abdominal distension and pain;heart rate and rhythm disorders,such as palpitation and increased heart rate.All of these ADRs were mild in severity.CONCLUSION:In this study the ADRs incidence rate of MI is very low,which supports that it is generally safe for use in obstetric and gynecological diseases.However,the total number of 8 ADRs recorded over a relatively short time span seems limited,and the low number of reports could not represent an absolute guarantee of safety. | Cao Shan Zhang Wenhao Zhao Ziwei Heng Mingli Bu Huaien Wang Hongwu Liu Xinghui Wang Zhong Cai Yan Ma Yuyan Cui Shihong Deng Jihong Ding Guifeng Ding Yajuan Dong Linhong Duan Zhentao Fan Ling Fan Yang Fu Fen He Jing Ji Shuying Jin Lin Li Hong Li Hongying Liao Tao Lu Wei Luo Xiucui Lü Zhihui Ma Fengchun Ma Dafeng Shi Tianyun Sun Juying Sun Xiaotong Teng Hong Wang Jinhua Wang Ruihua Wang Ying Wang Zhengling Xi Jie Xu Minjuan Xu Zhihong Yan Qian Yang Cuirong Yang Yimei Yin Jie Yu Jinhua Yuan Wenjun Zhang Guanli Zhang Meihua Zhao Renfeng Zhong Yonghong Zhou Jian | 2018 | Journal of Traditional Chinese Medicine2018，38，4： | 4 |
| 7 | Incidence of persistent and high-risk human papillomavirus infection and associated factors among HIV-positive women in China, 2015-2016显示文摘Background:Persistent human papillomavirus(HPV)infection is the necessary factor for cervical cancer.Human immunodeficiency virus(HIV)-positive women are a high-risk population for cervical cancer,but little is known about persistent HPV infection among HIV-positive women in China.We aimed to investigate the persistence and incidence of infection with high-risk HPV(hrHPV)and associated factors among HIV-positive women in China.Method:Using a prospective observational study design,we collected data from 670 HIV-positive women in five counties of three provinces through interviews,medical record reviews,health examination,and laboratory tests at a baseline survey in 2015 and a follow-up survey in 2016.We tested HIVpositive women for hrHPV infection using the Cobas 4800 HPV test,and analyzed factors associated with persistence and new incidence of hrHPV infection using logistic regression.Results:After an average of 15 months at follow-up,the persistence and new incidence rates of hrHPV infection were 38.0%(46/121,95%CI:29.2%-46.8%)and 8.3%(35/420,95%CI:5.7%-11.1%),respectively.HIV-positive women in Yunnan and Guangxi were more likely to have persistent hrHPV infections than those in Xinjiang(aOR=3.18,95%CI:1.00-10.14,p=0.05;aOR=6.38,95%CI:2.29-17.77,p<0.001).Migrant women had a higher rate of new hrHPV incidence than local women(aOR=4.48,95%CI:1.65-12.15,p=0.003).HIV-positive women from Xinjiang were 6.5 times more likely to be newly infected with hrHPV than those from Yunnan(95%CI:2.40-17.60,p<0.001).HIV-positive women with HBV infection had a higher risk of being infected with hrHPV than those without HBV infection(aOR=3.48,95%CI:1.13-10.71,p=0.029).Conclusions:The persistence and new incidence rates of hrHPV infection among HIV-positive women were high and varied significantly between regions.HBV infection and being among the migrant population were associated with new hrHPV infection. | Yaping Qiao Ailing Wang Liwen Fang Linhong Wang | 2021 | Gynecology and Obstetrics Clinical Medicine2021，1，3： | 2 |
| 8 | Associations Between Hypertension Status and Increased Heart Rate-China, 2015显示文摘Summary What is already known on this topic?Hypertension is a major public health concern in China,and hypertensive patients have elevated heart rates(HR),which can synergize with higher blood pressure to promote adverse health outcomes.What is added by this report?The risk of increased HR was statistically significant but relatively lower in subjects with treated and controlled hypertension.This lower impact might be modified by sex,marital status,smoking,and physical activity. | Xiao Zhang Mei Zhang Chun Li Linhong Wang Jing Wu Zhengjing Huang Limin Wang | 2020 | China CDC weekly2020，2，40： | 2 |
| 9 | In vitro assay of cytoskeleton nanomechanics as a tool for screening potential anticancer effects of natural plant extract, tubeimoside I on human hepatoma (HepG2) cells显示文摘Cytoskeleton nanomechanics characterizes cancer cell's physical behaviors such as how it spread and invade. For anticancer drug, cytoskeleton nanomechanics may be a target to inhibit invasiveness and metastasis of cancer cells. Therefore, in vitro assay of cytoskeleton nanomechanics may be used to evaluate the effects of potential anticancer drug on various cancer types. Here, we investigated the effects of tubeimoside I (TBMS I) on human hepatoma (HepG2) cells by using optical magnetic twisting cytometry, a well-established technique for measuring nanomechanics of the Factin cytoskeleton. TBMS I is a natural compound extracted from a traditional Chinese herbal medicine, and is reported with antitumor effect. In this study, we demonstrated that the cytoskeleton stiffness (G) of HepG2 cells was affected by TBMS I. G′ exhibited a typical power law with respect to the loading frequency (f), i.e. G^f . The magnitude of G′ and the value of exponent (α) of the HepG2 cells decreased consistently with the increase of concentration for TBMS I exposure. In addition, the HepG2 cells responded to TBMS I much faster than the normal liver (L-02) cells. Such alteration of cytoskeleton nanomechanics induced by TBMS I was reported for the first time, which was further corroborated by assays of Factin cytoskeleton structure and cell migration. Taken together, these results suggest that in vitro assay of cytoskeleton nanomechanics may have a great potential as an additional tool in screening of anticancer drug candidates. | ZHAO HongBo WANG YaShu JIANG XueMei SHI XiaoHao ZHONG HongZhe WANG YaJie CHEN Jun DENG LinHong | 2013 | Chinese Science Bulletin2013，58，21： | 2 |
| 10 | Knowledge of Cervical Cancer and HPV,and Willingness to Receive HPV Vaccination Among 20–45-Year-Old Women—Six Provinces,China,2018显示文摘Summary What is already known about this topic?Cervical cancer is a significant public health problem with approximately 570,000 cases and 311,000 deaths occurring in 2018 globally.It is imperative to raise awareness of cervical cancer and human papillomavirus(HPV).What is added by this report?Compared to previous studies,this is one of the largest cross-sectional studies of cervical cancer and HPV in Chinese adult females in recent years.We found that knowledge level of cervical cancer and HPV vaccine was still inadequate among women aged 20–45 years old,and the willingness to receive HPV vaccination was highly associated with knowledge level.What are the implications for public health practice?Intervention programs should aim to improve awareness and knowledge about cervical cancer and HPV vaccines,primarily focusing on women of lower socio-economic status. | Di Gao Gengli Zhao Jiangli Di Xiaosong Zhang Linhong Wang | 2023 | China CDC weekly2023，5，9： | 1 |
| 11 | Sunlight photocatalytic degradation of ofloxacin using UiO-66/wood composite photocatalysts显示文摘This study synthesized UiO-66(Zr)in situ on wood via a one-step solvothermal method.UiO-66/wood was successfully prepared and its catalytic performance for the ofloxacin(OFX)photodegradation under simulate sunlight was also explored.UiO-66/wood exhibited a better catalytic performance,and its degradation rate constant was about 1.2 and 1.5 times than that of UiO-66 and wood,respectively.The effects of solution initial concentration,pH of the system and dosage of the photocatalyst were explored.Additionally,the active species trapping experiments and UV-vis diffused reflectance spectra measurements were conducted to investigated the photocatalytic mechanism of the UiO-66/wood composite,superoxide radical(O_(2)^(·-))and hydroxyl radical(^(·)OH)were the main reactive species.In addition,the possible degradation pathways of OFX were analyzed by LC-MS.Meanwhile,the UiO-66/wood showed outstanding stability and reusability after 4 cycles experiments.The removal performance of UiO-66/wood towards real samples showed it has potential in actual application. | Linhong Shi Xue Zou Tengfei Wang Dongmei Wang Meikun Fan Zhengjun Gong | 2022 | Chinese Chemical Letters2022，33，1： | 1 |
| 12 | Expression of hMOF, but not HDAC4, is responsible for the global histoneH4K16 acetylation in gastric carcinoma显示文摘 | Lin Zhu Jiaxing Yang Linhong Zhao Xue Yu Lingyao Wang Fei Wang Yong Cai Jingji Jin | 2015 | International Journal of Oncology2015，，6： | 1 |
| 13 | Optimal charging plan for electric bus considering time-of-day electricity tariff显示文摘Purpose–The purpose of this study is to develop an optimization method for charging plans with the implementation of time-of-day(TOD)electricity tariff,to reduce electricity bill.Design/methodology/approach–Two optimization models for charging plans respectively with fixed and stochastic trip travel times are developed,to minimize the electricity costs of daily operation of an electric bus.The charging time is taken as the optimization variable.The TOD electricity tariff is considered,and the energy consumption model is developed based on real operation data.An optimal charging plan provides charging times at bus idle times in operation hours during the whole day(charging time is 0 if the bus is not get charged at idle time)which ensure the regular operation of every trip served by this bus.Findings–The electricity costs of the bus route can be reduced by applying the optimal charging plans.Originality/value–This paper produces a viable option for transit agencies to reduce their operation costs. | Yuhan Liu Linhong Wang Ziling Zeng Yiming Bie | 2022 | Journal of Intelligent and Connected Vehicles2022，5，2： | 1 |
| 14 | Low strain detection technology in pile foundation detection using 显示文摘 | Wang Linhong Shen Yijing | 2009 | technology2009，4，： | 1 |
| 15 | Analyzing dynamic character wasties of NC table with SVD 显示文摘 | WANG Linhong WU Bo | 2003 | International Symposium on Precwasion Mechanical Measurements2003，，9： | 1 |
| 16 | Accelerating Cervical Cancer Prevention and Control in China to Achieve Cervical Cancer Elimination Strategy Objectives显示文摘Cervical cancer is one of many types of cancers that severely threaten women’s health.Each year,604,000 new cases of cervical cancer appear with 342,000 related deaths globally.China represents about 18%of global incidences and 17%of global deaths(1).The China Cancer Registry’s annual report determined that,in 2020,world-standardized incidence rate of cervical cancer was 11.35 per 100,000 women—accompanied by a mortality rate of 3.42 per 100,000 women in China;further,both have demonstrated upward trends(2).Thus,China faces serious challenges with cervical cancer prevention and control:creating a major public health problem that severely threatens women’s health. | Linhong Wang | 2022 | China CDC weekly2022，4，48： | 1 |
| 17 | Prevalence of High-Risk Human Papillomavirus in Cervical Intraepithelial Neoplasia in the Pre-Vaccine Era—China,2017–2018显示文摘What is already known about this topic?Human papillomavirus(HPV)type-specific strategies play a key role in the prevention of cervical intraepithelial neoplasia(CIN),but evidence on the HPV type-specific prevalence in CIN is limited.What is added by this report?This multicentric study estimates the prevalence of high-risk HPV types in CIN cases and the associations of HPV infection patterns with high-grade CIN in China in 2017–2018.What are the implications for public health practice?Population-based prevention strategies should give preference to HPV-16 and 18,and strategies for non-16/18 high-risk HPV are essential for the elimination of cervical cancer. | Heling Bao Weihong Chen Xiaosong Zhang Hui Bi Yun Zhao Liwen Fang Shu Cong Feng Tan Linhong Wang | 2022 | China CDC weekly2022，4，48： | 1 |
| 18 | Future challenges and solutions for safety in China:China CDC’s exploration of injury prevention strategies显示文摘As an important component of worldwide injury prevention,China has made great contribution to the development.China is serving as a model for other countries in the world,especially developing countries,and China’s experience has great implications for them.Besides the description of the present situation and trends of China’s injury prevention work and review for its development history,this paper has also introduced the existing issues and the current challenges,and informed the e orts of the sta in related eld to nd solutions from di erent aspects.All of them jointly boosted the development of global injury prevention. | Leilei Duan Pengpeng Ye Linhong Wang | 2018 | Global Health Journal2018，2，2： | 1 |
| 19 | Inte-grated prevention of mother-to-child transmission for hu-man immunodeficiency virus, syphilis and hepatitis B vi-rus in China 显示文摘 | Wang Ailing Qiao Yaping Wang Linhong | 2015 | Bull World Health Organ2015，93，： | 1 |
| 20 | Age-specific effectiveness of primary human papillomavirus screening versus cytology in a cervical cancer screening program: a nationwide cross-sectional study显示文摘Background:Primary human papillomavirus(HPV)screening is recommended for the detection of cervical intraepithelial neoplasia(CIN)in the general pop-ulation;however,the triage for HPV-positive women remains a challenge.This study aimed to evaluate the age-specific effectiveness of primary HPV screening versus primary cytology screening for identifying optimal strategies for women of different ages.Methods:The dataset of the prevalence round screening was derived from the National Cervical Cancer Screening Program in China.Primary cervical screen-ing protocols included cytology only,HPV testing with cytology triage,and HPV testing with HPV-16/18 genotyping plus cytology triage.The primary outcomes were age-specific detection rate,colposcopy referral rate and positive predictive value(PPV)for CIN2+.Multivariate Poisson regression was used to evaluate the relativeeffectivenessofHPVtestingandcytologyaccordingtoagegroups.TheI 2 statisticwitharandom-effectmodelwasusedtotesttheheterogeneityinrelative effectiveness of HPV testing versus cytology between age groups.Results:This study included 1,160,981 women.HPV testing with HPV-16/18 genotyping plus cytology triage significantly increased the CIN2+detection by 36%(rate ratio[RR]:1.36,95%confidential interval[CI]1.21–1.54)for women aged 35-44 years and by 34%(RR:1.34,95%CI 1.20-1.51)for women aged 45-54 years compared with cytology only.HPV testing with cytology triage had simi-lar CIN2+detection rate compared with cytology only.The PPVs were substan-tially increased for both HPV testing groups.Among women aged 55-64 years old,HPV testing with HPV-16/18 genotyping plus cytology triage increased the colposcopyreferralrateby19%(RR1.19,95%CI1.10-1.29)comparedwithcytology only,butdidnotincreasetheCIN2+detection(1.09,0.91–1.30).Theeffectiveness ofHPVtestingwithcytologytriagedidnotchangeinolderwomen.Thebetween-age-group heterogeneity in the effectiveness was statistically significant for HPV testing with HPV-16/18 genotyping plus cytology triage versus cytology only.Conclusions:Our results suggested that the effectiveness of primary HPV screeningwithdifferenttriagestrategiesdifferedamongagegroups.HPVtesting with HPV-16/18 genotyping plus cytology triage could be used for women aged 35-54 years to detect more lesions,and HPV testing with cytology triage could balance the CIN2+detection and the number of colposcopies for women aged 55-64 years.Longitudinal data including both prevalence and incidence screen-ing rounds are warranted to assess age-specific triage strategies. | Heling Bao Lan Ma Yanxia Zhao Bo Song Jiangli Di Linhong Wang Yanqiu Gao Wenhui Ren Shi Wang Jiuling Wu Hai-Jun Wang | 2022 | Cancer Communications2022，42，3： | 1 |
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