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		题名	作者	年代	出处	被引量
	1	Phylogenetic and genetic characterization of a 2017 clinical isolate of H7N9 virus in Guangzhou,China during the fifth epidemic wave显示文摘Pathogenic H7N9 influenza viruses continue to pose a public health concern. The H7N9 virus has caused five outbreak waves of human infections in China since 2013. In the present study, a novel H7N9 strain(A/Guangdong/8 H324/2017) was isolated from a female patient with severe respiratory illness during the fifth wave of the 2017 H7N9 epidemic. Phylogenetic analysis showed that the H7N9 viruses collected during the fifth wave belong to two different lineages: the Pearl River Delta lineage and the Yangtze River Delta lineage. The novel isolate is closely related to the Pearl River Delta H7N9 viruses, which were isolated from patients in Guangdong Province. The novel H7N9 isolate has an insertion of three basic amino acids in the cleavage site of hemagglutinin(HA), which may enhance virulence in poultry. The 2017 isolate also possesses an R292 K substitution in the neuraminidase(NA)protein, which confers oseltamivir resistance. This study highlights the pandemic potential of the novel H7N9 virus in mammals;thus, future characterization and surveillance is warranted.	Yongqiang Deng Chunlin Li Jianfeng Han Yingfen Wen Jian Wang Wenxing Hong Xiaofeng Li Zhongyu Liu Qing Ye Jing Li Changshuai Zhou Lei Yu Chengfeng Qin Fuchun Zhang Tao Jiang	2017	Science China(Life Sciences)2017，60，12：	9
	2	Characteristic Class of Isotopy for Surfaces显示文摘It is an important problem in topology to verify whether two embeddings are isotopic.This work proposes an algorithm for computing Haefliger-Wu invariants for isotopy based on algebraic topological methods.Given a simplicial complex embedded in the Euclidean space,the deleted product of it is the direct product with diagonal removed.The Gauss map transforms the deleted product to the unit sphere.The pull-back of the generator of the cohomology group of the sphere defines characteristic class of the isotopy of the embedding.By using Mayer Vietoris sequence and Ku¨nneth theorem,the computational algorithm can be greatly simplified.The authors prove the ranks of homology groups of the deleted product of a closed surface and give explicit construction of the generators of the homology groups of the deleted product.Numerical experimental results show the efficiency and efficacy of the proposed method.	REN Yuxue WEN Chengfeng ZHEN Shengxian LEI Na LUO Feng GU David Xianfeng	2020	Journal of Systems Science & Complexity2020，33，6：	0

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