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| 1 | Whole-Genome Resequencing of a Worldwide Collection of Rapeseed Accessions Reveals the Genetic Basis of Ecotype Divergence显示文摘Rapeseed (Brassica napus),an important oilseed crop,has adapted to diverse climate zones and latitudes by forming three main ecotype groups,namely winter,semiwinter,and spring types. However,genetic variations underlying the divergence of these ecotypes are largely unknown. Here,we report the global pattern of genetic polymorphisms in rapeseed determined by resequencing a worldwide collection of 991 germplasm accessions.A total of 5.56 and 5.53 million singlenucleotide polymorphisms (SNPs)as Well as 1.86 and 1.92 million InDels were identified by mapping reads to the reference genomes of 'Darmor-bzh'and 'Tapidor,'respectively.We generated a map of allelic drift paths that shows splits and mixtures of the main populations,and revealed an asymmetric evolution of the two subgenomes of B.napus by calculating the genetic diversity and linkage disequilibrium parameters.Selective-sweep analysis revealed genetic changes in genes orthologous to those regulating various aspects of plant development and response to stresses.A genome-wide association study identified SNPs in the promoter regions of FLOWERING LOCUS T and FLOWERING LOCUS C orthologs that corresponded to the different rapeseed ecotype groups. Our study provides important insights into the genomic footprints of rapeseed evolution and flowering-time divergence among three ecotype groups,and will facilitate screening of molecular markers for accelerating rapeseed breeding. | Dezhi Wu Zhe Liang Tao Yan Ying Xu Lijie Xuan Juan Tang Gang Zhou Ulrike Lohwasser Shuijin Hua Haoyi Wang Xiaoyang Chen Qian Wang Le Zhu Antony Maodzeka Nazim Hussain Zhilan Li Xuming Li Imran Haider Shamsi Ghulam Jilani Linde Wu Hongkun Zheng Guoping Zhang Boulos Chalhoub Lisha Shen Hao Yu Lixi Jiang | 2019 | Molecular Plant2019，12，1： | 10 |
| 2 | Insecticide resistance in field populations of Laodelphax striatellus Fallen ( Homoptera : Delphacidae) in China and its possible mechanisms 显示文摘 | Gao Baoli Wu Juan Huang Shuijin | 2008 | Infl J Pest Manag2008，54，1： | 1 |
| 3 | Cadmium-induced functional and ultrastructural alterations in roots of two transgenic cotton cultivars显示文摘 | M.K. Daud Yuqiang Sun M. Dawood Y. Hayat M.T. Variath Yu-Xiang Wu Raziuddin Ullah Mishkat Salahuddin Ullah Najeeb Shuijin Zhu | 2008 | Journal of Hazardous Materials2008，，1： | 1 |
| 4 | Insecticide resistance in field populations of Laodelphax striatellus Fallen ( Homoptera : Delphacidae) in China and its possible mechanisms 显示文摘 | Gao Baoli Wu Juan Huang Shuijin | 2008 | International Journal of Pest Management2008，54，1： | 1 |
| 5 | Hui'an Women显示文摘Hui’an women prefer blue, apple green and black upper clothing and like to wear scarves and bamboo hats. | WU SHUIJIN LIN QIQUAN JENNIFER LIM | 1997 | Women of China1997，，12： | 0 |
| 6 | Regulation of Axon Initial Segment Diameter by COUP-TFI Fine-tunes Action Potential Generation显示文摘The axon initial segment(AIS)is a specialized structure that controls neuronal excitability via action potential(AP)generation.Currently,AIS plasticity with regard to changes in length and location in response to neural activity has been extensively investigated,but how AIS diameter is regulated remains elusive.Here we report that COUP-TFI(chicken ovalbumin upstream promotor-transcription factor 1)is an essential regulator of AIS diameter in both developing and adult mouse neocortex.Either embryonic or adult ablation of COUP-TFI results in reduced AIS diameter and impaired AP generation.Although COUP-TFI ablations in sparse single neurons and in populations of neurons have similar impacts on AIS diameter and AP generation,they strengthen and weaken,respectively,the receiving spontaneous network in mutant neurons.In contrast,overexpression of COUP-TFI in sparse single neurons increases the AIS diameter and facilitates AP generation,but decreases the receiving spontaneous network.Our findings demonstrate that COUP-TFI is indispensable for both the expansion and maintenance of AIS diameter and that AIS diameter fine-tunes action potential generation and synaptic inputs in mammalian cortical neurons. | Xuanyuan Wu Haixiang Li Jiechang Huang Mengqi Xu Cheng Xiao Shuijin He | 2022 | Neuroscience Bulletin2022，38，5： | 0 |
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