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| 1 | Biofunctional magnesium coated Ti6Al4V scaffold enhances osteogenesis and angiogenesis in vitro and in vivo for orthopedic application显示文摘The insufficient osteogenesis and osseointegration of porous titanium based scaffold limit its further application.Early angiogenesis is important for scaffold survival.It is necessary to develop a multifunctional surface on titanium scaffold with both osteogenic and angiogenic properties.In this study,a biofunctional magnesium coating is deposited on porous Ti6Al4V scaffold.For osseointegration and osteogenesis analysis,in vitro studies reveal that magnesium-coated Ti6Al4V co-culture with MC3T3-E1 cells can improve cell proliferation,adhesion,extracellular matrix(ECM)mineralization and ALP activity compared with bare Ti6Al4V cocultivation.Additionally,MC3T3-E1 cells cultured with magnesium-coated Ti6Al4V show significantly higher osteogenesisrelated genes expression.In vivo studies including fluorochrome labeling,micro-computerized tomography and histological examination of magnesium-coated Ti6Al4V scaffold reveal that new bone regeneration is significantly increased in rabbits after implantation.For angiogenesis studies,magnesium-coated Ti6Al4V improve HUVECs proliferation,adhesion,tube formation,wound-healing and Transwell abilities.HUVECs cultured with magnesium-coated Ti6Al4V display significantly higher angiogenesis-related genes(HIF-1αand VEGF)expression.Microangiography analysis reveal that magnesium-coated Ti6Al4V scaffold can significantly enhance the blood vessel formation.This study enlarges the application scope of magnesium and provides an optional choice to the conventional porous Ti6Al4V scaffold with enhanced osteogenesis and angiogenesis for further orthopedic applications. | Peng Gao Bo Fan Xiaoming Yu Wenwen Liu Jie Wu Lei Shi Di Yang Lili Tan Peng Wan Yulin Hao Shujun Li Wentao Hou Ke Yang Xiaokang Li Zheng Guo | 2020 | Bioactive Materials2020，5，3： | 15 |
| 2 | Changes in T lymphocyte subsets after severe traumatic brain injury显示文摘BACKGROUND: Besides local changes of cranial parenchymal cells, hemorrhage, etc., severe traumatic brain injuries also cause the changes of total body fluid and various functions, and the changes of lymphocytes and T lymphocyte subsets should be paid more attention to. OBJECTIVE: To reveal the changing laws of T lymphocyte subsets after severe traumatic brain injury, and compare with mild to moderate brain injury. DESIGN: A comparative observation. SETTINGS: Department of Neurosurgery, Longgang District Buji People's Hospital of Shenzhen City; Central Laboratory of Shenzhen Hospital of Prevention and Cure for Chronic Disease. PARTICIPANTS: All the subjects were selected from the Department of Neurosurgery, Longgang District Buji People's Hospital of Shenzhen City from August 2002 to August 2005. Thirty patients with severe brain injury, whose Glasgow coma score (GCS) was ≤ 8 points, were taken as the experimental group, including 21 males and 9 females, aging 16–62 years. Meanwhile, 30 patients with mild traumatic brain injury were taken as the control group (GCS ranged 14–15 points), including 18 males and 12 females, aging 15–58 years. All the subjects were in admission at 6 hours after injury, without disease of major organs before injury. Informed consents were obtained from all the patients or their relatives. METHODS: ① The T lymphocytes and the subsets in peripheral blood were detected with immunofluorescent tricolor flow cytometry at 1, 3, 7 and 14 days after injury in both groups. ② The conditions of pulmonary infections were observed at 4 days after injury. The differences of measurement data were compared with the t test. MAIN OUTCOME MEASURES: Changes of T lymphocytes subsets at 1–14 days after severe and mild or moderate traumatic injury. RESULTS: Finally, 28 and 25 patients with mild to moderate traumatic brain injury, whereas 25 and 21 patients with severe traumatic brain injury were analyzed at 7 and 14 days respectively, and the missed ones died due to the development of disease. ① Changes of T lymphocyte subsets: At 1 and 3 days after injury, CD3, CD4, CD8, CD4/CD8 began to decrease, whereas CD8 increased in the experimental group, which were very significantly different from those in the control group (t =2.77–3.26, P < 0.01), and began to recover at 7 days, which were significantly different from those in the control group (t = 2.06–2.24, P < 0.05), and generally recovered to the normal levels at 14 days (P > 0.05). ② Conditions of pulmonary infections: At 4 days after injury, the rate of pulmonary infection was significantly different between the experimental group and control group [73% (22/30), 0, χ2=37.29, P < 0.01]. CONCLUSION: Patients with severe traumatic brain injury suffer from damages of cellular immune function at early period (within 7 days), and they are easily to be accompanied by pulmonary infections. | Yulu Miao Mingxia Zhang Yulin Nie Wan Zhao Bin Huang Zhengming Jiang Shaoxiong Yu Zhibin Huang Hongjin Fu | 2007 | Neural Regeneration Research2007，2，2： | 7 |
| 3 | Compressed Sensing of IR-UWB Wireless Sensor Network Data Based on Two-Dimensional Measurements显示文摘A novel Compressed sensing(CS) method based on two-dimensional measurements is proposed that can be effectively utilized in Impulse radio ultra-wideband wireless sensor networks(IR-UWB WSNs) to significantly reduce the energy consumption and sampling rate in sensor data transferring. We start by establishing the CS measurement model by taking both spatial and temporal correlations of Wireless sensor network(WSN) data into account. Since our model incorporates a new type of measurement matrix: the block quasi-Toeplitz structured matrix, we derive the Restricted isometry property(RIP)of the block quasi-Toeplitz structured matrix to ensure the performance of the two-dimensional recovery of WSNs data. We substantiate our mathematical analysis by numerical examples in the context of ideal spares vector and real WSN data, and results demonstrate that the approach achieves significantly saving of energy and sampling rate with small reconstruction error. | WANG Kai LIU Yulin WAN Qun JING Xiaojun | 2015 | Chinese Journal of Electronics2015，24，3： | 3 |
| 4 | Compressed Sensing of Wireless Sensor Networks Data with Missed Measurements显示文摘In Wireless sensor networks(WSNs),missed measurements may be caused by the sensor malfunction and interruption of communication between sensor nodes. The feasibility of exact recovery of WSNs data with missed measurements is analyzed in the framework of compressed sensing. A new incomplete measurement model was developed and the data reconstruction algorithm was proposed. The required number of the missing measurements and the sparsity condition of network data are found for exact compressed sensing of WSNs data.Theoretical derivation shows that a WSNs data of length N with no more than M/(log(N/M) + 1) nonzero coefficients can be exactly recovered with M Gaussian measurements,provided that fraction of the missed measurements is less than a quarter of the Restricted isometry property(RIP)constant squared. Simulation results validate the theoretical results. | WANG Kai LIU Yulin WAN Qun JING Xiaojun | 2015 | Chinese Journal of Electronics2015，24，2： | 3 |
| 5 | Validation of the land-surface temperature products retrieved from Terra Moderate Resolution Imaging Spectroradiometer data显示文摘 | Zhengming Wan Yulin Zhang Qincheng Zhang Zhao-liang Li | 2002 | Remote Sensing of Environment2002，，1： | 2 |
| 6 | Validation of the land-surface temperature products retrieved from Terra Moderate Resolution Imaging Spectroradiometer data 显示文摘 | Wan Zhengming Zhang Yulin Zhang Qincheng | 2002 | Remote Sensing of Environment2002，83，： | 1 |
| 7 | Blind image data hiding based on self reference 显示文摘 | Wan Yulin Pearmain Alan | 2004 | Pattern Recognition letters2004，25，15： | 1 |
| 8 | Preparation and characterization of antibacterial viscose-based activated carbon fiber supporting silver显示文摘 | Wang Yulin Wan Yizao Dong Xianghong | 1998 | Carbon1998，36，11： | 1 |
| 9 | Enrichment and purification of total flavonoids from Flos Populi extracts with macroporous resins and evaluation of antioxidant activities in vitro显示文摘 | Pengfei Wan Zunlai Sheng Qiang Han Yulin Zhao Guangdong Cheng Yanhua Li | 2014 | Journal of Chromatography B2014，，： | 1 |
| 10 | Preliminary estimate of calibration of the moderate resolution imaging spectroradioeter thermal infrared data using Lake Titicaca 显示文摘 | Zhengming Wan Yulin Zhang Zhao-liang Li etc | 2002 | Remote Sensing of Environment2002，，80： | 1 |
| 11 | Zingiber officinale (ginger) compounds have tetracycline‐resistance modifying effects against clinical extensively drug‐resistant Acinetobacter baumannii显示文摘 | Hui‐MinWang Chung‐YiChen Hsi‐AnChen Wan‐ChunHuang Wei‐RuLin Tun‐ChiehChen Chun‐YuLin Hsin‐JuChien Po‐LiangLu Chiu‐MeiLin Yen‐HsuChen | 2010 | Phytother Res2010，，12： | 1 |
| 12 | Vali-dation of the land-surface temperature products retrieved fromTerra Moderate Resolution Imaging Spectroradiometerdata显示文摘 | Wan Zhengming Zhang Yulin Zhang Qincheng | 2002 | Remote Sensing of Environment2002，83，： | 1 |
| 13 | Validation of the land-surface temperature products retrieved from Terra Moderate Resolution Imaging Spectroradiometer data显示文摘 | Wan Zhengming Zhang Yulin Zhang Qincheng | 2002 | Remote Sensing of Environment2002，83，： | 1 |
| 14 | Preliminary estimate of calibration of the moderate- resolution imaging spectro-radiometer thermal infrared data using Lake Titicaca 显示文摘 | Wan Zhengming Zhang Yulin Li Zhaoliang | 2002 | Remote Sensing of Environment2002，80，： | 1 |
| 15 | Plasma Epstein‐Barr virus DNA screening followed by 18F‐fluoro‐2‐deoxy‐D‐glucose positron emission tomography in detecting posttreatment failures of nasopharyngeal carcinoma显示文摘 | Wen‐YiWang Chih‐WenTwu Wan‐YuLin Rong‐SanJiang Kai‐LiLiang Kuan‐WenChen Ching‐TeWu Yi‐TingShih Jin‐ChingLin | 2011 | Cancer2011，，19： | 1 |
| 16 | Rare Metal Materi- als and Engineering 显示文摘 | Mao Lihe Wang Yulin Wan Yizao | 2010 | 39(12): 2075 (in Chinese)2010，39，12： | 1 |
| 17 | Validation of the land-surface temperature products retrieved from Terra Moderate Resolution Imaging Spectroradiometer data显示文摘 | Wan Zhengrning Zhang Yulin Zhang Qincheng | 2002 | Remote Sensing of Environment2002，，83： | 1 |
| 18 | Submarine landslides, relationship with BSRs in the Dongsha area of South China Sea显示文摘Gas hydrate samples were first obtained in the Dongsha area,South China Sea(GMGS2)in 2013.High-resolution 3D seismic data in the area show various small 1andslide bodies developedas huge mass transport deposits.These bodies are divided into seven types on the basis of theirshapes,intermal structures and geneses(slide,collapse and deformation above BSRs,as well asthe slump wedge,lens,block and sheet below BSRs).Based on this classification,detailed studieswere conducted,including measurements of the slump body sizes and slope gradients of landslides,depiction of their three-dimensional characteristics,and research on the landslide distribution.Todetermine the genetic differences of these seven types,this study analyses the possibility of verticalflow-pattern-transformation and mechanisms of submarine landsltide formation.Results show that thedominant factor influencing the submarine landslides in the Dongsha area is the free gas emitted fromgas hydrate decomposition,with possible fransformation between flow patterns.Finally,there are twokinds of relationships between submarine landslides and BSRs since the free gas either influences thesubmarine landslide bodies below or above BSRs,resulting in two types of submarine landslide bodyassociations:Type A is characterized by submarine slide above BSRs and slump lens below BSRs,whereas Type B shows deformation above BSRs and slump blocks below BSRs.Type Ais favourablefor gas exploration because it indicates less decomposition and better sealing of gas hydrate layers. | Li Wan Xinghe Yu Tyson Steve Shunli Li Zenggui Kuang Zhibin Sha Jinqiang Liang Yulin He | 2016 | Petroleum Research2016，1，1： | 1 |
| 19 | Preliminary estimate of calibration of the moderate resolution imaging spectroradiometer thermal infrared data using Lake Titicaca显示文摘 | Wan Zhengming Zhang Yulin Li Zhaoliang | 2002 | Remote Sensing of Environment2002，80，： | 1 |
| 20 | Investigation into the epidemiology,genetic characteristics,and clinical manifestations of the first monkeypox outbreak in Shenzhen,China显示文摘This paper comprehensively analyses the first-ever monkeypox outbreak in Shenzhen,China,encompassing clinical symptomatology,therapeutic approaches,epidemiological research,and comprehensive laboratory tests,aiming to establish a robust reference for future monkeypox mitigation and management strategies.The investigation involved a thorough investigation of all identified positive cases,including extensive molecular analysis by nucleic acid detection and whole-genome sequencing of the monkeypox virus.Contact tracing and containment of the infected individuals were also undertaken.Three distinct monkeypox cases were identified in this unique outbreak,exhibiting mild and atypical clinical manifestations,primarily fever and rash.All cases were associated with a single transmission chain,primarily facilitated through close contact and homosexual behavior,indicative of a high-risk factor for monkeypox transmission. | Jia Wan Xiaomin Zhang Jing Qu Bo Peng Dongfeng Kong Jianhua Lu Qinghua Hu Zhifeng Zhou Haiduan Lin Xiangjie Yao Yulin Fu Qing Xu Ying Lin Yan Yang Jinzhen Tang Lin Lin Huimin Li Ziquan Lv Zhen Zhang Xuan Zou Xiaolu Shi | 2023 | Biosafety and Health2023，5，5： | 0 |
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