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| 1 | Diagnosis, treatment, and prevention of 2019 novel coronavirus infection in children: experts' consensus statement显示文摘Since the outbreak of 2019 novel coronavirus infection (2019-nCoV) in Wuhan City,China,by January 30,2020,a total of 9692 confirmed cases and 15,238 suspected cases have been reported around 31 provinces or cities in China.Among the confirmed cases,1527 were severe cases,171 had recovered and been discharged at home,and 213 died.And among these cases,a total of 28 children aged from 1 month to 17 years have been reported in China.For standardizing prevention and management of 2019-nCoV infections in children,we called up an experts' committee to formulate this experts' consensus statement.This statement is based on the Novel Coronavirus Infection Pneumonia Diagnosis and Treatment Standards (the fourth edition) (National Health Committee) and other previous diagnosis and treatment strategies for pediatric virus infections.The present consensus statement summarizes current strategies on diagnosis,treatment,and prevention of 2019-nCoV infection in children. | Kunling Shen Yonghong Yang Tianyou Wang Dongchi Zhao Yi Jiang Runming Jin Yuejie Zheng Baoping Xu Zhengde Xie Likai Lin Yunxiao Shang Xiaoxia Lu Sainan Shu Yan Bai Jikui Deng Min Lu Leping Ye Xuefeng Wang Yongyan Wang Liwei Gao | 2020 | World Journal of Pediatrics2020，16，3： | 56 |
| 2 | Research on proton radiation effects on CMOS image sensors with experimental and particle transport simulation methods显示文摘Recently,complementary metal-oxide semiconductor image sensors(CISs)have become a key element of the imaging instrument and have been widely used in many scientific applications[1,2]such as space remote sensing,medical imaging,and nuclear power plant monitoring.However,CISs used in these harsh radiation environments are susceptible to damage by particles or rays. | Yuanyuan XUE Zujun WANG Minbo LIU Baoping HE Zhibin YAO Jiangkun SHENG Wuying MA Guantao DONG Junshan JIN | 2017 | Science China(Information Sciences)2017，60，12： | 6 |
| 3 | Study on oil–source correlation by analyzing organic geochemistry characteristics: a case study of the Upper Triassic Yanchang Formation in the south of Ordos Basin, China显示文摘In the south of the Ordos Basin, the oil source of the Upper Triassic Yanchang Formation is confused all the time, which affects further exploration. In this study, oil sources from the oil layers of Ch6, Ch8 and Ch9 are all analyzed and confirmed. Through their carbon isotope value and biomarkers, characteristics of crude oils from the Yanchang Formation are analyzed. Then, the oil–source relation is discussed, with the source rocks' features.Finally, the oil–source relation is calculated through cluster analysis. It is believed that the oils from the Yanchang Formation deposit in a similar redox environment, with weak oxidation–weak reduction, and have all entered maturity stage. Ch9 crude oil is more mature than crude oils from Ch6 and Ch8, and has more advanced plants and fewer algae. Gas chromatography(GC) and gas chromatography–mass spectrometry(GC–MS) analysis show that crude oils from Ch6 and Ch8 may come from Ch7, and Ch9 crude oil may not. Cluster analysis displays that crude oils from Ch6 and Ch8 have closer squared Euclidean distance with Ch7 source rocks than Ch9 crude oil does,indicating crude oils from Ch6 and Ch8 stem from Ch7 source rocks. And Ch9 crude oil has rather close squared Euclidean distance with Ch9 source rocks, illustrating Ch9 crude oil may be from Ch9 source rocks. This research may provide the theoretical basis for the next exploration deploy in the south of Ordos Basin. | Delu Li Rongxi Li Baoping Wang Zhi Liu Xiaoli Wu Futian Liu Bangsheng Zhao Jinghua Cheng Wenbin Kang | 2016 | Acta Geochimica2016，35，4： | 5 |
| 4 | Scattering by circular cavity in radially inhomogeneous medium with wave velocity variation显示文摘Based on the theory of complex function and the principle of homogenization, harmonic dynamics stress of a radially infinite inhomogeneous medium with a circular cavity is investigated. Due to the symmetry, wave velocity is assumed to have power-law variation in the radial direction only, and the shear modulus is constant. The Helmholtz equation with a variable coefficient is equivalently transformed into a standard Helmholtz equation with a general conformal transformation method(GCTM). The displacements and stress fields are proposed. Numerical results show that the wave number and the inhomogeneity parameter of the medium have significant effects on the dynamic stress concentration around the circular cavity. The dynamic stress concentration factor(DSCF) becomes singular when the inhomogeneity parameter of medium is close to zero. | Zailin YANG Baoping HEI Yao WANG | 2015 | Applied Mathematics and Mechanics(English Edition)2015，36，5： | 4 |
| 5 | Comparison of the dark signal degradation induced by Gamma ray, proton, and neutron radiation in pinned photodiode CMOS image sensors显示文摘Dear editor,CMOS image sensors (CISs) present numerous advantages and have become feasible alternatives for CCDs (charge coupled devices) in satellite imaging system, nuclear industry, and particle detection (1–3)However, CISs used in these applications are often operated under harsh radiation environments and are susceptible to total ionizing dose (TID) and displacement damage. | Zujun WANG Yuanyuan XUE Wei CHEN Rui XU Hao NING Baoping HE Zhibin YAO Minbo LIU Jiangkun SHENG Wuying MA Guantao DONG | 2019 | Science China(Information Sciences)2019，62，6： | 4 |
| 6 | A grid-based clustering algorithm for wild bird distribution显示文摘 | Yuwei WANG Yuanchun ZHOU Ying LIU Ze LUO Danhuai GUO Jing SHAO Fei TAN Liang WU Jianhui LI Baoping YAN | 2013 | Frontiers of Computer Science2013，7，4： | 4 |
| 7 | Adaptive image enhancement algorithm based on fuzzy entropy and human visual characteristics显示文摘To overcome the shortcomings of the Lee image enhancement algorithm and its improvement based on the logarithmic image processing(LIP) model, this paper proposes what we believe to be an effective image enhancement algorithm. This algorithm introduces fuzzy entropy, makes full use of neighborhood information, fuzzy information and human visual characteristics.To enhance an image, this paper first carries out the reasonable fuzzy-3 partition of its histogram into the dark region, intermediate region and bright region. It then extracts the statistical characteristics of the three regions and adaptively selects the parameter αaccording to the statistical characteristics of the image's gray-scale values. It also adds a useful nonlinear transform, thus increasing the ubiquity of the algorithm. Finally, the causes for the gray-scale value overcorrection that occurs in the traditional image enhancement algorithms are analyzed and their solutions are proposed.The simulation results show that our image enhancement algorithm can effectively suppress the noise of an image, enhance its contrast and visual effect, sharpen its edge and adjust its dynamic range. | WANG Baoping MA Jianjun HAN Zhaoxuan ZHANG Yan FANG Yang GE Yimeng | 2018 | Journal of Systems Engineering and Electronics2018，29，5： | 3 |
| 8 | Transient analysis of 1D inhomogeneous media by dynamic inhomogeneous finite element method显示文摘The dynamic inhomogeneous finite element method is studied for use in the transient analysis of onedimensional inhomogeneous media.The general formula of the inhomogeneous consistent mass matrix is established based on the shape function.In order to research the advantages of this method,it is compared with the general finite element method.A linear bar element is chosen for the discretization tests of material parameters with two fictitious distributions.And,a numerical example is solved to observe the differences in the results between these two methods.Some characteristics of the dynamic inhomogeneous finite element method that demonstrate its advantages are obtained through comparison with the general finite element method.It is found that the method can be used to solve elastic wave motion problems with a large element scale and a large number of iteration steps. | Yang Zailin Wang Yao Hei Baoping | 2013 | Earthquake Engineering and Engineering Vibration2013，12，4： | 3 |
| 9 | Safety and efficacy of Yupingfeng granules in children with recurrent respiratory tract infection:A randomized clinical trial显示文摘Importance:Recurrent respiratory tract infection(RRTI)is common in children.Inappropriate RRTI treatment will lead to asthma and other diseases,thereby seriously affecting the growth and physical health of children.Immune function modulation can prevent and alleviate childhood RRTI.Yupingfeng(YPF),a patented traditional Chinese medicine(TCM),has immunomodulatory effects and is widely used in China to treat children with RRTI.Objective:To evaluate the safety and efficacy of YPF monotherapy in treating children with RRTI.Methods:This multicenter,randomized,double-blind,double-simulation,noninferiority clinical trial was conducted from January 2015 to August 2017,with an 8-week treatment period and 52-week follow-up after the drug withdrawal.Children aged 2–6 years with RRTI meeting the inclusion and exclusion criteria were enrolled in 13 hospitals in China and divided randomly into three groups(2:2:1 ratio)to receive YPF,pidotimod,or placebo.The primary outcome was the proportion of RRTI returning to normal standard level during the follow-up.The secondary outcomes were reduction in the number of RRTI recurrences,effect on clinical symptoms(in accord with TCM practice),effect per symptom,and safety.The trial was registered at the Chinese Clinical Trials Registry(www.chictr.org.cn)under the unique identifier ChiCTR-IPR-15006847.Results:Three hundred and fifty-one children were enrolled and randomly assigned to 3 groups;124,125,and 61 children in the YPF,pidotimod,and placebo groups,respectively,had completed the trial.During the follow-up,the proportion of RRTI returning to normal standard level was 73.13%,67.15%,and 38.81%with YPF,pidotimod,and placebo,respectively(P<0.0001).The proportion of cases who returned to normal standard level in the YPF group was 34.32%higher than that in the placebo group.The safety profile did not significantly differ among the groups.Interpretation:YPF granules were noninferior to the active control drug pidotimod oral solution for the treatment of RRTI in children,and were superior to placebo,with a high safety profile. | Baoping Xu Xinmin Li Siyuan Hu Yixiao Bao Fengmei Chen Zhimin Chen Yonggang Du Enmei Liu Yufeng Liu Qinghui Mou Baoling Su Bo Wang Jianwen Xu Guiping Xu Qiaozhi Yang Liwei Gao Xiaohui Liu Lei Li Rong Ma Kunling Shen | 2022 | Pediatric Investigation2022，6，2： | 3 |
| 10 | Green fluorescent protein (GFP) as a vital marker for studying the interaction of Phytophthora sojae and soybean显示文摘Transgenic Phytophthora sojae strains that produce green fluorescent protein (GFP) were obtained after stable DNA integration using the Hsp70 promoter and the Ham34 terminator of Bremia lactucae. The expression of GFP during different developmental stages of P. sojae was observed using fluorescent microscopy. Based on this reporter system, the histopathologic events caused by the pathogen in soybean leaves, hypocotyls and roots were monitored. Meanwhile, the difference in resistance between different soybean cultivars against P. sojae was analyzed microscopically in roots. The results indicate that GFP can be stably expressed in zoosporangia, zoospores, cysts, hyphae and oospores of P. sojae. Using the GFP marker, the infecting pathogens in leaves, hypocotyls and roots of host could be distinctly visualized. The germ tube length of cysts germinating on the roots of resistant cultivar Nannong 8848 was longer than that on the roots of susceptible cultivar Hefeng 35. These results show for the first time that this eukaryotic reporter can be used in P. sojae as a stable and vital marker, allowing the study of genetics of this hemibiotrophic pathogen. | CHEN XiaoRen CHENG BaoPing WANG XinLe DONG SuoMeng WANG YongLin ZHENG XiaoBo WANG YuanChao | 2009 | Chinese Science Bulletin2009，54，16： | 3 |
| 11 | Curing mechanism of alkaline phenolic resin with organic ester显示文摘To study the curing mechanism of alkaline phenolic resin with organic ester, three esters were chosen to react with three systems — alkaline phenolic resin, potassium hydroxide aqueous solution containing phenol, and potassium hydroxide aqueous solution. The variations of pH, heat release and gel pH during the reactions were monitored and measured. Infrared spectroscopy(IR) and thermal gravity analysis(TG) techniques were used to characterize the curing reaction. It was found that organic ester is only partially hydrolyzed and resin can be cured through organic ester hydrolysis process as well as the reaction with redundant organic ester. The sequential curing mechanism of alkaline phenolic resin cured by organic ester was identified as follows: a portion of organic ester is firstly hydrolyzed owing to the effect of the strong alkaline; the gel is then formed after the pH decreases to about 10.8-10.88, meanwhile, the redundant organic ester(i.e. non-hydrolysis ester) starts the curing reaction with the resin. It has also been found that the curing rate depends on the hydrolysis velocity of organic ester. The faster the hydrolysis speed of the ester, the faster the curing rate of the resin. | Huang Renhe Wang Yanmin Zhang Baoping | 2014 | China Foundry2014，11，5： | 3 |
| 12 | Derivation and characterization of human embryonic stem cell lines from poor quality embryos显示文摘Poor quality embryos discarded from in vitro fertilization (IVF) laboratories are good sources for deriving human embryonic stem cell (hESC) lines. In this study, 166 poor quality embryos donated from IVF centers on day 3 were cultured in a blastocyst medium for 2 days, and 32 early blastocysts were further cultured in a blastocyst optimum culture medium for additional 2 days so that the inner cell masses (ICMs) could be identified and isolated easily. The ICMs of 17 blastocysts were isolated by a mechanical method, while those of the other 15 blastocysts were isolated by immunosurgery. All isolated ICMs were inoculated onto a feeder layer for subcultivation. The rates of ICM at- tachment, primary ICM colony formation and the efficiency of hESC derivation were similar between the ICMs isolated by the two methods (P>0.05). As a result, four new hESC lines were established. Three cell lines had normal karyotypes and one had an unbalanced Robertsonian translocation. All cell lines showed normal hESC characteristics and had the differentiation ability. In conclusion, we established a stable and effective method for hESC isolation and culture, and it was confirmed that the mechanical isolation was an effective method to isolate ICMs from poor embryos. These results further indicate that hESC lines can be derived from poor quality embryos discarded by IVF laboratories. | Weiqiang Liu, Yifei Yin, Xiaolin Long, Yumei Luo, Yonghua Jiang, Wenhong Zhang, Hongzi Du, Shaoying Li, Yuhong Zheng, Qing Li, Xinjie Chen, Baoping Liao, Guohong Xiao, Weihua Wang, Xiaofang Sun Guangzhou Key Laboratory of Reproductive and Genetics Institute of Gynecology and Obstetrics, The Third Affiliated Hospital of Guangzhou Medical College, Guangzhou 510150, China | 2009 | Journal of Genetics and Genomics2009，36，4： | 3 |
| 13 | Effects of rotational tillage practices on soil properties, winter wheat yields and water-use efficiency in semi-arid areas of north-west China显示文摘 | Xianqing Hou Rong Li Zhikuan Jia Qingfang Han Wei Wang Baoping Yang | 2012 | Field Crops Research2012，，： | 2 |
| 14 | Image segmentation algorithm based on high-dimension fuzzy character and restrained clustering network显示文摘An image segmentation algorithm of the restrained fuzzy Kohonen clustering network(RFKCN) based on highdimension fuzzy character is proposed. The algorithm includes two steps. The first step is the fuzzification of pixels in which two redundant images are built by fuzzy mean value and fuzzy median value. The second step is to construct a three-dimensional(3-D)feature vector of redundant images and their original images and cluster the feature vector through RFKCN, to realize image segmentation. The proposed algorithm fully takes into account not only gray distribution information of pixels, but also relevant information and fuzzy information among neighboring pixels in constructing 3-D character space. Based on the combination of competitiveness,redundancy and complementary of the information, the proposed algorithm improves the accuracy of clustering. Theoretical analyses and experimental results demonstrate that the proposed algorithm has a good segmentation performance. | Baoping Wang Yang Fang Chao Sun | 2014 | Journal of Systems Engineering and Electronics2014，25，2： | 2 |
| 15 | Modeling dark signal of CMOS image sensors irradiated by reactor neutron using Monte Carlo method显示文摘The dark signal degradation of the CMOS image sensor(CIS) was induced by neutron radiation,and it was modeled by Geant4, which is a three-dimensional Monte Carlo code. The simplified model of the CIS array was established according to the actual pixel geometry, material, and doping concentration. Nuclear elastic interaction and capture interaction were included in the physical processes, and the displacement damage dose in the space charge region of the pixel was calculated. The mean dark signal and dark signal distribution were modeled using Geant4, and the physical mechanisms were analyzed. The modeling results were in good agreement with the experimental and theoretical results. | Yuanyuan XUE Zuun WANG Wei CHEN Baoping HE Zhibin YAO Minbo LIU Jiangkun SHENG Wuying MA Guantao DONG Junshan JIN | 2018 | Science China(Information Sciences)2018，61，6： | 2 |
| 16 | Genetic Analysis of Human Adenovirus Type 7 Strains Circulating in Different Parts of China显示文摘To investigate the molecular epidemiology and genetic variation of human adenovirus type 7(HAdV-7)in children with acute respiratory infections(ARI)in China.HAdV-7-positive respiratory samples collected from children with ARI in Beijing,Shijiazhuang,Wenzhou and Guangzhou from 2014–2018 were selected for gene amplification and sequence analysis.Fifty-seven HAdV-7 clinical strains with hexon,penton base and fiber gene sequences were obtained.Meanwhile17 strains were selected randomly from different cities for whole genome sequencing.Phylogenetic and variation analyses were performed based on the obtained sequences,HAdV-7 prototype strain Gomen(AY594255),vaccine strains(AY495969 and AY594256)and representative sequences of strains.The phylogenetic trees constructed based on whole genome sequences,major capsid protein genes(hexon,penton base and fiber)and the early genes(E1,E2,E3 and E4)were not completely consistent.The HAdV-7 strains obtained in this study always clustered with most of the circulating strains worldwide from the 1980 s to the present.Compared with the HAdV-7 prototype strain Gomen(AY594255),some amino acid mutations in loop1 and loop2 of hexon and the RGD loop region of the penton base gene were observed.Recombination analysis showed that partial regions of 55 k Da protein and 100 kDa hexon-assembly associated protein genes among all HAdV-7 strains in this study were from HAdV-16 and HAdV-3,respectively.Our study demonstrated the molecular evolution characteristics of HAdV-7 strains circulating in China and provided basic reference data for the prevention,control and vaccine development of HAdV-7. | Yali Duan Changchong Li Li Deng Shuhua An Yun Zhu Wei Wang Meng Zhang Lili Xu Baoping Xu Xiangpeng Chen Zhengde Xie | 2021 | Virologica Sinica2021，36，3： | 2 |
| 17 | A multi-center study on Molecular Epidemiology of Human Respiratory Syncytial Virus from Children with Acute Lower Respiratory Tract Infections in the Mainland of China between 2015 and 2019显示文摘Human respiratory syncytial virus(RSV) is a major pathogen of acute lower respiratory tract infection among young children. To investigate the prevalence and genetic characteristics of RSV in China, we performed a molecular epidemiological study during 2015–2019. A total of 964 RSV-positive specimens were identified from 5529 enrolled patients during a multi-center study. RSV subgroup A(RSV-A) was the predominant subgroup during this research period except in2016. Totally, 535 sequences of the second hypervariable region(HVR-2) of the G gene were obtained. Combined with182 Chinese sequences from GenBank, phylogenetic trees showed that 521 RSV-A sequences fell in genotypes ON1(512),NA1(6) and GA5(3), respectively;while 196 RSV-B sequences fell in BA9(193) and SAB4(3). ON1 and BA9 were the only genotypes after December 2015. Genotypes ON1 and BA9 can be separated into 10 and 7 lineages, respectively. The HVR-2 of genotype ON1 had six amino acid changes with a frequency more than 10%, while two substitutions H258 Q and H266 L were co-occurrences. The HVR-2 of genotype BA9 had nine amino acid substitutions with a frequency more than10%, while the sequences with T290 I and T312 I were all from 2018 to 2019. One N-glycosylation site at 237 was identified among ON1 sequences, while two N-glycosylation sites(296 and 310) were identified in the 60-nucleotide duplication region of BA9. To conclusion, ON1 and BA9 were the predominant genotypes in China during 2015–2019. For the genotypes ON1 and BA9, the G gene exhibited relatively high diversity and evolved continuously. | Xiangpeng Chen Yun Zhu Wei Wang Changchong Li Shuhua An Gen Lu Rong Jin Baoping Xu Yunlian Zhou Aihuan Chen Lei Li Meng Zhang Zhengde Xie | 2021 | Virologica Sinica2021，36，6： | 2 |
| 18 | Investigation of Discharge Characteristic of Shadow Mask PDP显示文摘 | Tu Yan Wang Baoping Zhang Xiong | 2005 | IMID052005，，： | 1 |
| 19 | Investigation of breakdown characteristic of a novel plasma display panel discharge cell with rotationally symmetric structure 显示文摘 | Tu Yan Zhang Xiong Wang Baoping | 2002 | Journal of Vacuum Science2002，20，1： | 1 |
| 20 | Parametric Narrow-Band InISAR 3D Imaging Based on Compressed Sensing显示文摘For muti-scatter point target and undersampled data,tradintional imaging method has a poor precision for imaging result and spin angular velocity.In view of the above problems,this paper proposes a narrow-band Interferometric inverse synthetic aperture radar(InISAR)3-dimensional(3D)Compressed sensing imaging method based on the joint spin angle velocity error parameter estimation.First,a sparse model of narrow-band spin target is constructed.Then,the image entropy is used as the criterion function to search the optimal angle velocity by the joint reconstruction iteration.Finally,the image of the target is obtained by interference processing.The simulation results show that compared with the traditional method,the estimation of spin angular velocity and the imaging result are more accurate in proposed method. | WANG Baoping ZHANG Yan FANG Yang SONG Zuxun | 2020 | Chinese Journal of Electronics2020，29，3： | 1 |
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