|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Contemporary crustal movement of continental China obtained by global positioning system(GPS) measurements显示文摘We obtain a unified horizontal velocity field of continental China and vicinity through measurements at 81 GPS stations provided by the National Key Infrastructure Project, Crustal Movement Observation Network of China. The velocity field delineates patterns of movements and deformation of active crustal blocks in continental China under the Eurasia-fixed reference frame. The space-based geodesy also clearly shows for the first time the horizontal movementand deformation of continental China induced by indentation of the Indian plate. The data provide kinematic constraints for simulating dynamic process of continental litho-spheric deformation. | MA Zongjin, CHEN Xinlian, YE Shuhua, LAI Xian, WEI Ziqing, CHEN Junrong, NING Jinsheng, XU Huoze & DING Guoyu1. Insitute of Geology, China Seismological Bureau, Beijing 100029, China (e-mail: disgroup@publi.bta.net.cn)2. Center for Analysis and Prediction, China Seismological Bureau, Beijing 100036, China 3. Shanghai Astronomic Observatory, Chinese Academy of Sciences, Shanghai 200030, China 4. Institute of Seismology, China Seismological Bureau, Wuhan 430077, China 5. Institute of Survey and Mapping, Xi’an 710054, China 6. National Bureau of Survey and Mapping, Beijing 100830, China 7. Wuhan University, Wuhan 430077, China 8. Institute of Geodesy and Geophysics, Wuhan 430077, China 9. China Seismological Bureau, Beijing 100036, China | 2001 | Chinese Science Bulletin2001，46，18： | 34 |
| 2 | Antioxidant effects of the orientin and vitexin in Trollius chinensis Bunge in D-galactose-aged mice显示文摘Total flavonoids are the main pharmaceutical components of Trollius chinensis Bunge, and orientin and vitexin are the monomer components of total flavonoids in Trollius chinensis Bunge. In this study, an aged mouse model was established through intraperitoneal injection of D-galactose for 8 weeks, followed by treatment with 40, 20, or 10 mg/kg orientin, vitexin, or a positive control (vitamin E) via intragastric administration for an additional 8 weeks. Orientin, vitexin, and vitamin E improved the general medical status of the aging mice and significantly increased their brain weights. They also produced an obvious rise in total antioxidant capacity, superoxide dismutase, catalase, and glutathione peroxidase levels in the serum, and the levels of superoxide dismutase, catalase and glutathione peroxidase, Na+-K+-ATP enzyme, and Ca2+-Mg2+-ATP enzyme in the liver, brain and kidneys. In addition, they significantly reduced malondialdehyde levels in the liver, brain and kidney and lipofuscin levels in the brain. They also significantly improved the neuronal ultrastructure. The 40 mg/kg dose of orientin and vitexin had the same antioxidant capacity as vitamin E. These experimental findings indicate that orientin and vitexin engender anti-aging effects through their antioxidant capacities. | Fang An Guodong Yang Jiaming Tian Shuhua Wang | 2012 | Neural Regeneration Research2012，7，33： | 20 |
| 3 | Distinct characteristics and new prognostic scoring system for Chinese patients with Waldenstr(o)m macroglobulinemia显示文摘 | Yi Shuhua Cui Rui Li Zengjun An Gang Qi Junyuan Zou Dehui Zhang Peihong Chen Huishu Wang Jianxiang Chang Hong Qiu Lugui | 2014 | Chinese Medical Journal2014，，12： | 12 |
| 4 | The Pedagogical Content Knowledge of Middle School, Mathematics Teachers in China and the U.S.显示文摘 | Shuhua An Gerald Kulm Zhonghe Wu | 2004 | Journal of Mathematics Teacher Education2004，，2： | 2 |
| 5 | Thermal stability of nanocrystalline W-Ti diffusion barrier thin films显示文摘Nanocrystalline W-Ti diffusion barrier thin films with different phase structures and Cu/barrier/Si multilayer structures were deposited on p-type Si(100) substrates by DC magnetron sputtering.These films were annealed at different temperatures for 1 h.The diffusion barrier properties and thermal stability were studied using four-probe tester(FPP),XRD,AFM,XPS,FESEM,and HRTEM.The experimental results showed that the films were stable up to 700℃.When the annealing temperature was increased,the Cu and Ti atoms began to react and CuTi3 was formed.In addition,the high resistance Cu3Si was formed due to inter-diffusion between the Si and Cu atoms which made the surface rougher and caused the sheet resistance to increase abruptly.At the same time,failure mechanism of the nanocrystalline W-Ti diffusion barrier thin films during annealing process was also discussed. | WANG QingXiang,FAN ZhiKang & LIANG ShuHua School of Materials Science and Engineering,Xi’an University of Technology,Xi’an 710048,China | 2010 | Science China(Technological Sciences)2010，53，4： | 2 |
| 6 | Genetic Analysis of Human Adenovirus Type 7 Strains Circulating in Different Parts of China显示文摘To investigate the molecular epidemiology and genetic variation of human adenovirus type 7(HAdV-7)in children with acute respiratory infections(ARI)in China.HAdV-7-positive respiratory samples collected from children with ARI in Beijing,Shijiazhuang,Wenzhou and Guangzhou from 2014–2018 were selected for gene amplification and sequence analysis.Fifty-seven HAdV-7 clinical strains with hexon,penton base and fiber gene sequences were obtained.Meanwhile17 strains were selected randomly from different cities for whole genome sequencing.Phylogenetic and variation analyses were performed based on the obtained sequences,HAdV-7 prototype strain Gomen(AY594255),vaccine strains(AY495969 and AY594256)and representative sequences of strains.The phylogenetic trees constructed based on whole genome sequences,major capsid protein genes(hexon,penton base and fiber)and the early genes(E1,E2,E3 and E4)were not completely consistent.The HAdV-7 strains obtained in this study always clustered with most of the circulating strains worldwide from the 1980 s to the present.Compared with the HAdV-7 prototype strain Gomen(AY594255),some amino acid mutations in loop1 and loop2 of hexon and the RGD loop region of the penton base gene were observed.Recombination analysis showed that partial regions of 55 k Da protein and 100 kDa hexon-assembly associated protein genes among all HAdV-7 strains in this study were from HAdV-16 and HAdV-3,respectively.Our study demonstrated the molecular evolution characteristics of HAdV-7 strains circulating in China and provided basic reference data for the prevention,control and vaccine development of HAdV-7. | Yali Duan Changchong Li Li Deng Shuhua An Yun Zhu Wei Wang Meng Zhang Lili Xu Baoping Xu Xiangpeng Chen Zhengde Xie | 2021 | Virologica Sinica2021，36，3： | 2 |
| 7 | A multi-center study on Molecular Epidemiology of Human Respiratory Syncytial Virus from Children with Acute Lower Respiratory Tract Infections in the Mainland of China between 2015 and 2019显示文摘Human respiratory syncytial virus(RSV) is a major pathogen of acute lower respiratory tract infection among young children. To investigate the prevalence and genetic characteristics of RSV in China, we performed a molecular epidemiological study during 2015–2019. A total of 964 RSV-positive specimens were identified from 5529 enrolled patients during a multi-center study. RSV subgroup A(RSV-A) was the predominant subgroup during this research period except in2016. Totally, 535 sequences of the second hypervariable region(HVR-2) of the G gene were obtained. Combined with182 Chinese sequences from GenBank, phylogenetic trees showed that 521 RSV-A sequences fell in genotypes ON1(512),NA1(6) and GA5(3), respectively;while 196 RSV-B sequences fell in BA9(193) and SAB4(3). ON1 and BA9 were the only genotypes after December 2015. Genotypes ON1 and BA9 can be separated into 10 and 7 lineages, respectively. The HVR-2 of genotype ON1 had six amino acid changes with a frequency more than 10%, while two substitutions H258 Q and H266 L were co-occurrences. The HVR-2 of genotype BA9 had nine amino acid substitutions with a frequency more than10%, while the sequences with T290 I and T312 I were all from 2018 to 2019. One N-glycosylation site at 237 was identified among ON1 sequences, while two N-glycosylation sites(296 and 310) were identified in the 60-nucleotide duplication region of BA9. To conclusion, ON1 and BA9 were the predominant genotypes in China during 2015–2019. For the genotypes ON1 and BA9, the G gene exhibited relatively high diversity and evolved continuously. | Xiangpeng Chen Yun Zhu Wei Wang Changchong Li Shuhua An Gen Lu Rong Jin Baoping Xu Yunlian Zhou Aihuan Chen Lei Li Meng Zhang Zhengde Xie | 2021 | Virologica Sinica2021，36，6： | 2 |
| 8 | Thermal conductivity of boron nitride reinforced polyethylene composites显示文摘 | Zhou Wenying Qi Shuhua An Qunli | 2007 | Materials Research Bulletin2007，42，10： | 1 |
| 9 | The Pedagogical Content Knowledge of Middle School, Mathematics Teachers in China and the U.S.显示文摘 | Shuhua An Gerald Kulm Zhonghe Wu | 2004 | Journal of Mathematics Teacher Education2004，，2： | 1 |
| 10 | Thermal conductivity of boron nitride reinforced polyethylene com- posites显示文摘 | Zhou Wenying Qi Shuhua An Qunli | 2007 | Mater Res Bull2007，42，10： | 1 |
| 11 | The Role of Hemofiltration in the Treatment of Severe Acute Pancreatitis显示文摘 | An Shuguang Guo Shuhua | 2012 | China Modern Doctor2012，59，23： | 1 |
| 12 | Thermal conductivity of boron nitride reinforced polyethylene composites 显示文摘 | Zhou Wenying Qi Shuhua An Qunli | 2007 | Material Research Bulletin2007，42，10： | 1 |
| 13 | Thermal, electrical, and mechanical properties of Si3 N4 filled LLDPE composite 显示文摘 | An Qunli Qi Shuhua Zhou Wenying | 2009 | Polymer Composites2009，30，7： | 1 |
| 14 | Thermal, Electri- cal, and Mechanical Properties of SiaN4 Filled LLDPE Composite 显示文摘 | An Qunti Oi Shuhua Zhou Wenying | 2009 | Polymer Composites2009，30，7： | 1 |
| 15 | Thermal conductivity of boron nitride reinforced polyethylene composites显示文摘 | Wenying Zhou Shuhua Qi Qunli An Hongzhen Zhao Nailiang Liu | 2006 | Materials Research Bulletin2006，，10： | 1 |
| 16 | Thermal, electrical, and mechanicalp roperties of Si3N4 filled LLDPE composite 显示文摘 | An Qunli Qi Shuhua Zhou Wenying | 2009 | Polym Compos2009，30，7： | 1 |
| 17 | Thermal conductivity of boron nitride reinforced polyethylene composites显示文摘 | Wenying Zhou Shuhua Qi Qunli An | 2007 | Materials Research Bulletin2007，42，： | 1 |
| 18 | Thermal conductivity of boron nitride reinforced polyethylene composites 显示文摘 | ZHOU Wenying QI Shuhua AN Qunli | 2007 | Mater Res Bull2007，42，10： | 1 |
| 19 | The Pedagogical Content Knowledge of Middle School, Mathematics Teachers in China and the U.S.显示文摘 | Shuhua An Gerald Kulm Zhonghe Wu | 2004 | Journal of Mathematics Teacher Education2004，，2： | 1 |
| 20 | Exosome miRNAs profiling in serum and prognostic evaluation in patients with multiple myeloma显示文摘MicroRNAs(MiRNAs)carried by exosomes play pivotal roles in the crosstalk between cell components in the tumor microenvironment.Our study aimed at identifying the expression profile of exosomal miRNAs(exo-miRNAs)in the serum of multiple myeloma(MM)patients and investigating the regulation networks and their potential functions by integrated bioinformatics analysis.Exosomes in serum from 19 newly diagnosed MM patients and 9 healthy donors were isolated and the miRNA profile was investigated by small RNA sequencing.Differential expression of exo-miRNAs was calculated and target genes of miRNAs were predicted.CytoHubba was applied to identify the hub miRNAs and core target genes.The LASSO Cox regression model was used to develop the prognostic model,and the ESTIMATE immune score was calculated to investigate the correlation between the model and immune status in MM patients.The top six hub differentially expressed serum exo-miRNAs were identified.513 target genes of the six hub exo-miRNAs were confirmed to be differentially expressed in MM cells in the Zhan Myeloma microarray dataset.Functional enrichment analysis indicated that these target genes were mainly involved in mRNA splicing,cellular response to stress,and deubiquitination.13 core exo-miRNA target genes were applied to create a novel prognostic signature to provide risk stratification for MM patients,which is associated with the immune microenvironment of MM patients.Our study comprehensively investigated the exo-miRNA profiles in MM patients.A novel prognostic signature was constructed to facilitate the risk stratification of MM patients with distinct outcomes. | Teng Fang Hao Sun Xiyue Sun Yi He Peixia Tang Lixin Gong Zhen Yu Lanting Liu Shiyi Xie Tingyu Wang Zhenshu Xu Shuhua Yi Gang An Yan Xu Guoqing Zhu Lugui Qiu Mu Hao | 2023 | Blood Science2023，5，3： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员