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| 1 | Nodal Type Bound States for Nonlinear Schrodinger Equations with Decaying Potentials显示文摘 | LUO Tingjian WANG Zhengping | 2012 | Journal of Partial Differential Equations2012，25，1： | 0 |
| 2 | Detecting Anomalous Bus-Driving Behaviors from Trajectories显示文摘In urban transit systems,discovering anomalous bus-driving behaviors in time is an important technique for monitoring the safety risk of public transportation and improving the satisfaction of passengers.This paper proposes a two-phase approach named Cygnus to detect anomalous driving behaviors from bus trajectories,which utilizes collected sensor data of smart phones as well as subjective assessments from bus passengers by crowd sensing.By optimizing support vector machines,Cygnus discovers the anomalous bus trajectory candidates in the first phase,and distinguishes real anomalies from the candidates,as well as identifies the types of driving anomalies in the second phase.To improve the anomaly detection performance and robustness,Cygnus introduces virtual labels of trajectories and proposes a correntropy-based policy to improve the robustness to noise,combines the unsupervised anomaly detection and supervised classification,and further refines the classification procedure,thus forming an integrated and practical solution.Extensive experiments are conducted on real-world bus trajectories.The experimental results demonstrate that Cygnus detects anomalous bus-driving behaviors in an effective,robust,and timely manner. | Zhao-Yang Wang Bei-Hong Jin Tingjian Ge Tao-Feng Xue | 2020 | Journal of Computer Science & Technology2020，35，5： | 0 |
| 3 | Development of a Prognostic Index for Kidney Cancer Based on Hypoxia Landscape显示文摘Objective:Kidney cancer is a group of cancers occurred in the kidney.Hypoxia is a condition characterized by insuff-cient oxygen supply in the body or specifie organs.It has been proven to play an essential role in the pathogenesis and development of various cancer.However,the roles and mechanisms of hypoxia in kidney cancer have not been investigated clearly.In this study,we comprehensively analyzed the roles of hypoxia in kidney cancer.Methods:The RNA-Seq data of kidney cancer were downloaded from TCGA dataset.The survival of patients with diffentially expressed hypoxia-related genes was analyzed with the survival package.The prognostic value of hypoxia-related genes was evaluated with univariate Cox regression analysis.The correlation of hypoxia-related genes to immune ells infiltration and gene mutation in kidney cancer was assessed.We identifed 7 hypoxia-related genes of kidney cancer,with which we developed a hypoxia-related genes-based prognostic index using multivariate Cox regression analysis to establish the prog-nostic model.Results:The high-risk group showed lower survival compared with the low-risk group.HRGPI was an independent pre-dictor of kidney cancer,and it was associated with malignant stages.Hypoxia-related genes were correlated to activation of inflammatory pathways,infiltration of inflammatory ellls,and expression of inhibitory immune checkpoints,indicat ing that hypoxia was related to im-mune response in kidney cancer.Lastly,we found that hypoxia was related to missense mutation in kidney cancer.Conclusion:Hy-poxia is a risk factor of kidney cancer.It can be regarded as the prognostic indicator and therapeutic target for the treatment of kidney cancer in the future. | Wang Hesong Feng Yanyan Wang Ting Feng Yuyin Jiang Haixu Wang Tingjian Huang Guangrui | 2021 | 肿瘤预防与治疗2021，34，11： | 0 |
| 4 | Discrimination of TCM constitutions by biochemical and routine urine indexes显示文摘Objective:To investigate whether the specific traditional Chinese medicine(TCM)constitution of individuals can be defined by certain biological indexes instead of answering the questionnaire,and to explore the possibility of discriminating nine TCM constitutions from each other simultaneously using biological indexes.Methods:Blood and urine samples from 152 individuals with nine TCM constitutions were collected,and the related biological indexes were analyzed combining ANOVA,multiple comparison,discriminant analysis,and support vector machine.Results:We found that 4 out of 24 blood routine indexes,7 out of 10 urine routine indexes,and 12 out of 32 biochemical indexes showed differences among the constitutions.High-sensitivity C-reactive protein,apolipoprotein A1,and alkaline phosphatase were potential candidates for screening out individuals with unbalanced constitutions.Combining uric acid,high-density lipoprotein,apolipoprotein A1,creatine kinase,total protein,aspartate aminotransferase,total bile acid,dehydrogenase,sodium,and calcium levels had the potential to directly distinguish the nine TCM constitutions from each other.Among these indexes,the highest ratio of discriminant analysis between two constitutions was 95.5%,while the lowest was 66.1%.Conclusion:Our results suggest that some biochemical and urine indexes are related to various TCM constitutions,and thus they have the potential to be used for TCM constitution classification. | Xiaoling Liu Pengfei Zhao Jianhua Zhen Shen Zhang Hesong Wang Yuxiu Sun Wei Wang Tingjian Wang Kaiwen Hu Guangrui Huang | 2022 | Journal of Traditional Chinese Medical Sciences2022，9，2： | 0 |
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