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| 1 | Ultrasonically activated scalpel versus monopolar electrocautery shovel in laparoscopic total mesorectal excision for rectal cancer显示文摘AIM: To investigate the feasibility and safety of monopolar electrocautery shovel (ES) in laparoscopic total mesorectal excision (TME) with anal sphincter preservation for rectal cancer in order to reduce the cost of the laparoscopic operation, and to compare ES with the ultrasonically activated scalpel (US). METHODS: Forty patients with rectal cancer, who underwent laparoscopic TME with anal sphincter preservation from June 2005 to June 2007, were randomly divided into ultrasonic scalpel group and monopolar ES group, prospectively. White blood cells (WBC) were measured before and after operation, operative time, blood loss, pelvic volume of drainage, time of anal exhaust, visual analogue scales (VAS) and surgery-related complications were recorded. RESULTS: All the operations were successful; no one was converted to open procedure. No significant differences were observed in terms of preoperative and postoperative d 1 and d 3 WBC counts (P = 0.493, P = 0.375, P = 0.559), operation time (P = 0.235), blood loss (P = 0.296), anal exhaust time (P = 0.431), pelvicdrainage volume and VAS in postoperative d 1 (P = 0.431, P = 0.426) and d 3 (P = 0.844, P = 0.617) between ES group and US group. The occurrence of surgery-related complications such as anastomotic leakage and wound infection was the same in the two groups. CONCLUSION: ES is a safe and feasible tool as same as US used in laparoscopic TME with anal sphincter preservation for rectal cancer on the basis of the skillful laparoscopic technique and the complete understanding of laparoscopic pelvic anatomy. Application of ES can not only reduce the operation costs but also benef it the popularization of laparoscopic operation for rectal cancer patients. | Bao-Jun Zhou, Wei-Qing Song, Qing-Hui Yan, Jian-Hui Cai, Feng-An Wang, Jin Liu, Guo-Jian Zhang, Guo-Qiang Duan, Zhan-Xue Zhang, Department of Gastrointestinal Surgery, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei Province, China Author contributions: Zhou BJ, Song WQ, Yan QH, Cai JH, Wang FA, Liu J, Zhang GJ, Duan GQ and Zhang ZX contributed equally to this work Zhou BJ, Song WQ, Yan QH, Cai JH and Wang FA designed the research Zhou BJ, Liu J and Zhang GJ performed the research Duan GQ and Zhang ZX analyzed the data and Zhou BJ, Song WQ and Yan QH wrote the paper. | 2008 | World Journal of Gastroenterology2008，14，25： | 25 |
| 2 | Effect of extracorporeal bioartificial liver support system on fulminant hepatic failure rabbits显示文摘AIM To evaluate the possibility of usingcultured human hepatocytes as a bridge betweenbioartificial liver and liver transplantation.METHODS In this experiment,the efficacy ofextracorporeal bioartificial liver support system(EBLSS)consisting of spheriodal human livercells and cultured hepatocytes supernatant wasassessed in vivo using galactosamine inducedrabbit model of fulminant hepatic failure.RESULTS There was no difference of survivalbetween the two groups of rabbits,but in thesupported rabbits serum alanineaminotransferase,total bilirubin and creatininewere significantly lower and hepatocyte necrosiswas markedly milder than those in controlanimals.In addition,a good viability of humanliver cells was noted after the experiment.CONCLUSION EBLSS plays a biologic role inmaintaining and compensating the function ofthe liver. | Wang YJ Li MD Wang YM Chen GZ Lu GD Tan ZX | 2000 | World Journal of Gastroenterology2000，6，2： | 17 |
| 3 | Pulmonary infection control window in treatment of severe respiratory failure of chronic obstructive pulmonary diseases: a prospective, randomized controlled, multi-centred study显示文摘Background Early withdraw from invasive mechanical ventilation (MV) followed by noninvasive MV is a new strategy for changing modes of treatment. This study was conducted to estimate the feasibility and the efficacy of early extubation and sequential noninvasive MV commenced at beginning of pulmonary infection control window in patients with exacerbated hypercapnic respiratory failure caused by chronic obstructive pulmonary diseases (COPD). Methods A prospective, randomized controlled study was conducted in eleven teaching hospitals' respiratory or medical intensive care units in China. Ninety intubated COPD patients with severe hypercapnic respiratory failure triggered by pulmonary infection (pneumonia or purulent bronchitis) were involved in the study. When the pulmonary infection had been controlled by antibiotics and comprehensive therapy, the 'pulmonary infection control window (PIC window)' has been reached. Each case was randomly assigned to study group (extubation and noninvasive MV via facial mask immediately) or control group (invasive MV was received continuously after PIC window by using conventional weaning technique).Results Study group (n=47) and control group (n=43) had similar clinical characteristics initially and at the time of PIC window. Compared with control group, study group had shorter duration of invasive MV [(6.4±4.4) days vs (11.3±6.2) days, P=0.000], lower rate of ventilator associated pneumonia (VAP) (3/47 vs 12/43, P=0.014), fewer days in ICU [(12±8) days vs (16±11) days, P=0.047] and lower hospital mortality (1/47 vs 7/43, P=0.025).Conclusions In COPD patients requiring intubation and invasive MV for hypercapnic respiratory failure, which is exacerbated by pulmonary infection, early extubation followed by noninvasive MV initiated at the start of PIC window may decrease significantly the duration of invasive MV, the risk of VAP and hospital mortality. | Wang, C Zhan, QY Cao, ZX Wei, LQ Cheng, ZZ Liu, S Zhang, JL Chen, RC Luo, Q Niu, SF Zhu, L Wu, DW Fang, BM Wu, TH Wang, CZ Liu, YN | 2005 | Chinese Medical Journal2005，，19： | 6 |
| 4 | DETERMINATION OF EFFECTIVE MODULI FOR FOAM PLASTICS BASED ON THREE PHASE SPHEROIDAL MODEL显示文摘The relations of bulk modulus,shear modulus,Young’s modulus and the Poisson’s ra-tio with porosity of foam plastics are determined by a three phase spheroidal model commonly used inComposite Mechanics.The results are compared with those using differential scheme.It is shownthat the material properties derived from the present model normally are larger than those obtained bydifferential scheme for foam plastics with identical porosity.The differences in shear moduli andYoung’s moduli obtained by the two methods are small,but they are larger for bulk moduli of incom-pressible matrix and Poisson’s ratios.The Young’s moduli of high density foam plastics derived by thepresent model agree better with experimental ones. | Lu, ZX Huang, ZP Wang, R | 1995 | Acta Mechanica Solida Sinica1995，8，4： | 3 |
| 5 | Expression of gap junctions and inhibition of cell growth in communication-defected cells after transfection with gap junction gene Cx43 cDNA显示文摘Gap junctions form intercellular channels for direct exchange of metabolites and second messengers between adjacent cells. The existence of a multi-gene family encoding gap junction proteins, i. e. the connexins (Cx), has been recently demonstrated. Despite the overall sequence homologies and a similar predicted structural motif, their functional properties differ in various tissues. Because of coexpression of two or more connexin proteins in one tissue, determination of properties specific for each connexin is complicated. The regulation of expression of gap junctions and their roles in cellular activities remain mostly unelucidative. Controlled manipulation of connexin molecules in Xenopus oocyte expression system has been use- | Zhang, ZQ Lin, ZX Wang, NQ Han, YL | 1997 | Chinese Science Bulletin1997，42，5： | 3 |
| 6 | A NEW TRITERPENOID FROM THE FUNGUS GANODERMA LUCIDUM显示文摘A NEW TRITERPENOID FROM THE FUNGUS GANODERMA LUCIDUMFangShengWANG;HuiCAI;ZaiXinJING(UniversityofAgricultureandAnimalScience.P... | Wang, FS Cai, H Jing, ZX Yang, JS Zhang, YM | 1995 | Chinese Chemical Letters1995，6，12： | 2 |
| 7 | Ocular flmgal isolates and antifungal susceptibility in northern China 显示文摘 | Sun XG Wang ZX Wang ZQ Luo SY Li R | 2007 | Am J Ophthalmol2007，143，： | 1 |
| 8 | Inhibition of xenogeneic response in porcine endothelium using RNA interference显示文摘 | Zhu M Wang SS Xia ZX | 2005 | Transplantation2005，79，3： | 1 |
| 9 | 显示文摘 | Fan YJ Wang SW Sun ZX | 2012 | Mater Chem Phys2012，134，1： | 1 |
| 10 | Anti- IL-2 receptor antibody decreases cytokine- induced apoptosis of human renal tubular epithelial cells(TEC )显示文摘 | WANG S ZHANG ZX YIN Z | 2011 | Nephrol Dial Transplant2011，26，7： | 1 |
| 11 | Decreased tobacco-specific nitrosamines by microbial treatment with Bacillus amyloliquefaciens DA9 during the Air-Curing process of burley tobacco 显示文摘 | Wei XT Deng XW Cai DB Ji ZX Wang CJ Yu J Li JP and Chen SW | 2014 | J Agric Food Chem2014，62，12： | 1 |
| 12 | MicroRNA -21:a novel therapeutic target in human cancer显示文摘 | Pan X Wang ZX Wang R | 2010 | Cancer Biol Ther2010，10，12： | 1 |
| 13 | Evolution of soil chemical properties in the past 50 years in the Tai Lake Region, China显示文摘 | Wang H Dong YH Li DC Velde B An Q Guo ZX Zuo QD | 2008 | Soil and Tillage Research2008，100，12： | 1 |
| 14 | The current status of occupational health in China 显示文摘 | Zhang XY Wang ZX Li T | 2010 | Environ Health Prev Med2010，15，5： | 1 |
| 15 | Association analyses identify six new psoriasis susceptibility loci in the Chinese population 显示文摘 | Sun LD Cheng H Wang ZX | 2010 | Nat Genet2010，42，11： | 1 |
| 16 | Distribution of hepatitis C virus genotypes in Chinese patients with chronic hepatitis Ccorrelation with patients' characteristics and clinical param- eters 显示文摘 | Dong ZX Zhou HJ Wang JH | 2012 | J Dig Dis2012，13，11： | 1 |
| 17 | Hyperactivation of working memory-related brain circuits in newly diagnosed middle-aged type 2 diabetics显示文摘 | He XS Wang ZX Zhu YZ | 2015 | Acta Diabetol2015，52，1： | 1 |
| 18 | Improved survival outcomes with the incidental use of beta-blockers among patients with non- small-cell lung cancer treated with definitive radiation therapy 显示文摘 | Wang HM Liao ZX Komaki R | 2013 | Ann Oncol2013，24，5： | 1 |
| 19 | Analysis of clinical and dosi- metric factors associated with treatment-related pneumonitis (THP) in patients with non-small-cell lung cancer (NSCLC) treated with concurrent chemotherapy and three-dimensional conformaI radiotherapy(3DCRT)显示文摘 | Wang S Liao ZX Wei X | 2006 | Int J Radiat Oncol Biol Phys2006，66，5： | 1 |
| 20 | Hypoxia specific SDF-1 expression by retinal pigment epithelium initiates bone marrow-derived cells to participate in choroidal neovascularization in a laser-induced mouse model显示文摘 | ZHANG ZX WANG YS SHI YY HOU HY ZHANG C CAI Y | 2011 | Curt Eye Res2011，36，9： | 1 |
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