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117篇 您的检索式:作者名="Watkins R D"
    题名 作者 年代 出处 被引量
1胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 2017中华高血压杂志2017,25,9:2
2Taste-aversion conditioning of house mice (Mus domesticus) using the non-lethal repellent, cinnamamide显示文摘Watkins R W Gurney J E Cowan D P 1998Appl Anim Behav Sci1998,,57:2
3Evidence for the involvement of spinal cord glia in subcutaneous formalin induced hyperalgesia in the rat显示文摘Watkins L R Martin D Ulrich P 1997Pain1997,71,3:1
4Associations between serum perfluo roalkyl acids and LINE-1 DNA methylation 显示文摘Watkins D J Wellanius G A Buffer R A 2014Environment International2014,63,:1
5Evidence for the involvement of spinal cord glia in subcutaneous formalin induced hyperalgesia in the rat 显示文摘Watkins L R Martin D Ulrich P 1997Pain1997,71,3:1
62001 Identification of novel,functional genetic variants in the human matrix metalloproteinase-2 gene:role of Sp1 in allele specific tanscriptional regulation显示文摘PRICE S J GREAVES D R WATKINS H 2001J Biol Chem2001,276,:1
7查看详情显示文摘Drew K Renfrew P. D Craven T. W Butterfoss G.L. Chou F.C. Lyskov S. Bullock B.N. Watkins A. Labonte J.W. Pacella M. Kilambi K.P. Leaver-Fay A. Kuhlman B. Gray J.J. Bradley P. Kirshenbaum K. Arora P.S. Das R. Bonneau R 0,,7:1
8Optimization for incororation risk and uncertainty in sustainable water resources planning 显示文摘WATKINS D W MCKINNEY J R DAENE C R 1995International Association of Hydrological Sciences1995,231,13:1
9Linear Programming for Flood Control in the Iowa and Des Moines Rivers显示文摘Needham J T Watkins D W Lund J R 2000Journal of Water Resources Planning and Management2000,126,3:1
10Cadmium exposure down- regulates 8 - oxoguanine DNA glycosylase expression in rat lung and alveolar epithelial cells 显示文摘Potts R J Watkin R D Hart B A 2003Toxicology2003,18,23:1
11Determination of gold binding in an algal biomass using EXAFS and XANES spectroscopies 显示文摘Watkins J W Elder R C Greene B Darnall D W 1987Inorganic Chemistry1987,26,7:1
12Glial activation:a driving force for pathological pain显示文摘Watkins L R Milligan E D Maier S F 2001Trends Neurosci2001,24,8:1
13Glial activation: adriving force for pathological pain显示文摘WATKINS L R MILLIGAN E D MAIER S F 2001Trends Neurosci2001,24,8:1
14Occurrence of malespecific bacteriophage inferal and domesticanimal wastes,human feces and human-associated waste waters显示文摘Calei K R Burkhardt W Watkins W D 1998Appl Environ Microbiol1998,64,12:1
15A fisher phase locking two beams by means of seeded Brillouin scattering显示文摘Loree T R Watkins D E Johnson T M 1987Opt Lett1987,12,:1
16Metabolicchanges in I-methylcyclopropene(I-MCP)-treated ‘Empire’ ap-ple fruit during storage显示文摘LEE J RUDELL D R DAVIES P J WATKINS C B 2012Metabolomics2012,8,4:1
17Spinal cord glia: new player in pain显示文摘Watkins L R Milligan E D Maier S F 2001Pain2001,93,3:1
18Normal remodeling of the oxygen-injured lung requires the cyclin- dependent kinase inhibitor p21 ( Cip1/ WAF1/Sdi1) 显示文摘Staversky R J Watkins RH Wright TW Hemady E LoMonaco MB D'Angio CT 2002Am J Pathol2002,161,3:1
19Glial activation: a driving force for pathological pain显示文摘Watkins L R Milligan E D Maier S F 2001Trends Neurosci2001,24,8:1
20Pathological and protective roles of glia in chronic pain显示文摘Milligan E D Watkins L R 2009Neuroscience2009,10,1:1
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