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| 1 | Time-frequency response spectrum of rotational ground motion and its application显示文摘The rotational seismic motions are estimated from one station records of the 1999 Jiji (Chi-Chi), Taiwan, earthquake based on the theory of elastic plane wave propagation. The time-frequency response spectrum (TFRS) of the rota-tional motions is calculated and its characteristics are analyzed, then the TFRS is applied to analyze the damage mechanism of one twelve-storey frame concrete structure. The results show that one of the ground motion components can not reflect the characteristics of the seismic motions completely; the characteristics of each component, especially rotational motions, need to be studied. The damage line of the structure and TFRS of ground motion are important for seismic design, only the TFRS of input seismic wave is suitable, the structure design is reliable. | Wei Che Qifeng Luo | 2010 | Earthquake Science2010，23，1： | 15 |
| 2 | Hes1 Knockdown Exacerbates Ischemic Stroke Following tMCAO by Increasing ER Stress-Dependent Apoptosis via the PERK/ eIF2a/ATF4/CHOP Signaling Pathway显示文摘Apoptosis induced by endoplasmic reticulum(ER)stress plays a crucial role in mediating brain damage after ischemic stroke.Recently,Hes1(hairy and enhancer of split 1)has been implicated in the regulation of ER stress,but whether it plays a functional role after ischemic stroke and the underlying mechanism remain unclear.In this study,using a mouse model of ischemic stroke via transient middle cerebral artery occlusion(tMCAO),we found that Hes1 was induced following brain injury,and that siRNA-mediated knockdown of Hes1 increased the cerebral infarction and worsened the neurological outcome,suggesting that Hes1 knockdown exacerbates ischemic stroke.In addition,mechanistically,Hes1 knockdown promoted apoptosis and activated the PERK/eIF2a/ATF4/CHOP signaling pathway after tMCAO.These results suggest that Hes1 knockdown promotes ER stress-induced apoptosis.Furthermore,inhibition of PERK with the specific inhibitor GSK2606414 markedly attenuated the Hes1 knockdown-induced apoptosis and the increased cerebral infarction as well as the worsened neurological outcome following tMCAO,implying that the protection of Hes1 against ischemic stroke is associated with the amelioration of ER stress via modulating the PERK/eIF2a/ATF4/CHOP signaling pathway.Taken together,these results unveil the detrimental role of Hes1 knockdown after ischemic stroke and further relate it to the regulation of ER stress-induced apoptosis,thus highlighting the importance of targeting ER stress in the treatment of ischemic stroke. | Yueyong Li Yingjun Zhang Huangde Fu Huadong Huang Qifeng Lu Houji Qin Yingning Wu Huatuo Huang Guizhen Mao Zhongheng Wei Pinhu Liao | 2020 | Neuroscience Bulletin2020，36，2： | 12 |
| 3 | Torsional phenomena in 2008 great Wenchuan earthquake显示文摘It is well known that there are some torsional damages in earthquakes. In Taibai park, Jiangyou city, Sichuan province, most of the stone statues, which were placed upon the banisters of one zigzag bridge, exhibited different torsional phenomena in 2008 Wenchuan earthquake. This paper introduces the torsional phenomena of all the statues on the zigzag bridge firstly. Then one eccentricity model is established and the equivalent rotational accelerations are calculated in order to analyze the causes of the torsional damage. In addition, the torsional components are synthesized by using translation accelerations recorded at Jiangyou station in the Wenchuan earthquake. The results show that the equivalent rotational acceleration is larger than the synthesized rotational components, which suggests that the torsional phenomena of the statues on the zigzag bridge might mainly come from its eccentricity. The comparison between the estimated torsional component at Jiangyou and that presented by Trifunac shows that they are in the same order. The research im-plies that the torsional phenomena in earthquakes are very complicated, and not only caused by torsional motions. | Fan Yang Qifeng Luo Wei Che | 2010 | Earthquake Science2010，23，1： | 4 |
| 4 | Serum semaphorin 4C as a diagnostic biomarker in breast cancer:A multicenter retrospective study显示文摘Background:To date,there is no approved blood-based biomarker for breast cancer detection.Herein,we aimed to assess semaphorin 4C(SEMA4C),a pivotal protein involved in breast cancer progression,as a serum diagnostic biomarker.Methods:We included 6,213 consecutive inpatients from Tongji Hospital,Qilu Hospital,and Hubei Cancer Hospital.Training cohort and two validation cohorts were introduced for diagnostic exploration and validation.A pan-cancer cohort was used to independently explore the diagnostic potential of SEMA4C among solid tumors.Breast cancer patients who underwent mass excision prior to modified radical mastectomy were also analyzed.We hypothesized that increased pretreatment serum SEMA4C levels,measured using optimized in-house enzymelinked immunosorbent assay kits,could detect breast cancer.The endpoints were diagnostic performance,including area under the receiver operating characteristic curve(AUC),sensitivity,and specificity.Post-surgery pathological diagnosis was the reference standard and breast cancer staging followed the TNM classification.There was no restriction on disease stage for eligibilities.Results:We included 2667 inpatients with breast lesions,2378 patients with other solid tumors,and 1168 healthy participants.Specifically,118 patients with breast cancer were diagnosed with stage 0(5.71%),620 with stage I(30.00%),966 with stage II(46.73%),217 with stage III(10.50%),and 8 with stage IV(0.39%).Patients with breast cancer had significantly higher serum SEMA4C levels than benign breast tumor patients and normal controls(P<0.001).Elevated serum SEMA4C levels had AUC of 0.920(95%confidence interval[CI]:0.900–0.941)and 0.932(95%CI:0.911–0.953)for breast cancer detection in the two validation cohorts.The AUCs for detecting early-stage breast cancer(n=366)and ductal carcinoma in situ(n=85)were 0.931(95%CI:0.916–0.946)and 0.879(95%CI:0.832–0.925),respectively.Serum SEMA4C levels significantly decreased after surgery,and the reduction was more striking after modified radical mastectomy,compared with mass excision(P<0.001).The positive rate of enhanced serum SEMA4C levels was 84.77%for breast cancer and below 20.75%for the other 14 solid tumors.Conclusions:Serum SEMA4C demonstrated promising potential as a candidate biomarker for breast cancer diagnosis.However,validation in prospective settings and by other study groups is warranted. | Ya Wang Long Qiao Jie Yang Xiong Li Yaqi Duan Jiahao Liu Shaoqi Chen Huayi Li Dan Liu Tian Fang Jingjing Ma Xiaoting Li Fei Ye Junxiang Wan Juncheng Wei Qin Xu Ensong Guo Ping Jin Mingfu Wu Lin Zhang Yun Xia Yaqun Wu Jun Shao Yaojun Feng Qing Zhang Zongyuan Yang Gang Chen Qinghua Zhang Xingrui Li Shixuan Wang Junbo Hu Xiaoyun Wang Mona P.Tan Kazuaki Takabe Beihua Kong Qifeng Yang Ding Ma Qinglei Gao | 2021 | Cancer Communications2021，41，12： | 3 |
| 5 | Prognostic and incremental value of computed tomography-based radiomics from tumor and nodal regions in esophageal squamous cell carcinoma显示文摘Objective:This study aimed to evaluate the prognostic value of preoperative radiomics and establish an integrated model for esophageal squamous cell cancer(ESCC).Methods:A total of 931 patients were retrospectively enrolled in this study(training cohort,n=624;validation cohort,n=307).Radiomics features were obtained by contrast-enhanced computed tomography(CT)before esophagectomy.A radiomics index was set based on features of tumor and reginal lymph nodes by using the least absolute shrinkage and selection operator(LASSO)Cox regression.Prognostic nomogram was built based on radiomics index and other independent risk factors.The prognostic value was assessed by using Harrell’s concordance index,time-dependent receiver operating characteristics and Kaplan-Meier curves.Results:Twelve radiomic features from tumor and lymph node regions were identified to build a radiomics index,which was significantly associated with overall survival(OS)in both training cohort and validation cohort.The radiomics index was highly correlated with clinical tumor-node-metastasis(cTNM)and pathologic TNM(pTNM)stages,but it demonstrated a better prognostic value compared with cTNM stage and was almost comparable with pTNM stage.Multivariable Cox regression showed that the radiomics index was an independent prognostic factor.An integrated model was constructed based on gender,preoperative serum sodium concentration,pTNM and the radiomics index for clinical usefulness.The integrated model demonstrated discriminatory ability better compared with the traditional clinical-pathologic model and pTNM alone,indicating incremental value for prognosis.Conclusions:CT-based radiomics for primary tumor and reginal lymph nodes was sufficient in predicting OS for patients with ESCC.The integrated model demonstrated incremental value for prognosis and was robust for clinical applications. | Bangrong Cao Kun Mi Wei Dai Tong Liu Tianpeng Xie Qiang Li Jinyi Lang Yongtao Han Lin Peng Qifeng Wang | 2022 | Chinese Journal of Cancer Research2022，34，2： | 3 |
| 6 | Study of the electrodeposition conditions of metallic manganese in an electrolytic membrane reactor显示文摘 | Qifeng Wei Xiulian Ren Jie Du Sijie Wei SuRong Hu | 2010 | Minerals Engineering2010，，7： | 2 |
| 7 | Study of the electrodeposition conditions of metallic manganese in an electrolytic membrane reactor显示文摘 | WEI Qifeng REN Xiulian DU Jie | 2010 | Minerals Engineering2010，23，7： | 1 |
| 8 | Knowledge networks formation and interchain coupling of knowledge chains显示文摘 | QIFENG WEI XIN GU | 2013 | Journal of Applied Sciences2013，13，20： | 1 |
| 9 | VCAM-1 Promotes Osteolytic Expansion of Indolent Bone Micrometastasis of Breast Cancer by Engaging α4β1-Positive Osteoclast Progenitors显示文摘 | Xin Lu Euphemia Mu Yong Wei Sabine Riethdorf Qifeng Yang Min Yuan Jun Yan Yuling Hua Benjamin J. Tiede Xuemin Lu Bruce G. Haffty Klaus Pantel Joan Massagué Yibin Kang | 2011 | Cancer Cell2011，，6： | 1 |
| 10 | Study of the Electro- deposition Conditions of Metallic Manganese in an Electro- lytic Membrane Reactor显示文摘 | Wei Qifeng Ren Xiulian Du Jie | 2010 | Miner Eng2010，23，7： | 1 |
| 11 | Efficient degradation of organic pollutants by S-NaTaO_(3)/biochar under visible light and the photocatalytic performance of a permonosulfate-based dual-effect catalytic system显示文摘Removing large concentrations of organic pollutants from water efficiently and quickly under visible light is essential to developing photocatalytic technology and improving solar energy efficiency.This study used a simple hydrothermal method to prepare a non-metallic,S-doped NaTaO_(3)(S-NTO) photocatalyst,which was then loaded onto biochar (BC) to form a S-NTO/BC composite photocatalyst.After uniform loading onto BC,the S-NTO particles transformed from cubic to spherical.The photogenerated electron-hole pair recombination probability of the composite photocatalyst was significantly lower than those of the NTO particles.The light absorption range of the catalyst was effectively widened from 310 nm UV region to visible region.In addition,a dual-effect catalytic system was constructed by introducing peroxymonosulfate (PMS) into the environment of the pollution to be degraded.The Rhodamine B,Methyl Orange,Acid Orange 7,tetracycline,and ciprofloxacin degradation efficiency at 40 mg/L reached 99.6%,99.2%,84.5%,67.1%,and 70.7%,respectively,after irradiation by a 40 W lamps for 90 min.The high-efficiency visible-light catalytic activity of the dual-effect catalytic system was attributed to doping with non-metallic sulfur and loading of catalysts onto BC.The development of this dual-effect catalytic system provides new ideas for quickly and efficiently solving the problem of high-concentration organic pollution in aqueous environments,rationally and fully utilizing solar energy,and expanding the application of photocatalytic technology to practice. | Yuehui Tai Jinlong Sun Haoran Tian Fuyue Liu Boyu Han Wei Fu Zhangpei Liu Xiuye Yang Qifeng Liu | 2023 | Journal of Environmental Sciences2023，，3： | 1 |
| 12 | Study on the suitable thickness of a PAC-preeoated dynamic membrane coupled with a bioreactor for municipal wastewater treatment显示文摘 | Maosheng Ye Hanmin Zhang Qifeng Wei | 2006 | Desalination2006，194，： | 1 |
| 13 | Study on the suitable thickness of a PAC-precoated dynamic membrane coupled with a bioreactor for municipal wastewater treatment 显示文摘 | Ye Maosheng Zhang Hanmin Wei Qifeng | 2006 | Desalination2006，194，13： | 1 |
| 14 | MTDH Activation by 8q22 Genomic Gain Promotes Chemoresistance and Metastasis of Poor-Prognosis Breast Cancer显示文摘 | Guohong Hu Robert A. Chong Qifeng Yang Yong Wei Mario A. Blanco Feng Li Michael Reiss Jessie L.-S. Au Bruce G. Haffty Yibin Kang | 2009 | Cancer Cell2009，，1： | 1 |
| 15 | Electrodeposition Conditions of Metallic Nickel in Electrolytic Membrane Reactor显示文摘 | Ren Xiu1ian Wei Qifeng Liu Zhe | 2012 | Trans Nonferrous Met Soc China2012，22，： | 1 |
| 16 | The recovery of zinc from hot galvanizing slag in an anion - exchange mem- brane electrolysis reactor显示文摘 | Ren Xiulian Wei Qifeng Hu Surong | 2010 | Jottrnal of Hazardous Materials2010，181，1： | 1 |
| 17 | 3D Printing of NiCoP/Ti3C2 MXene Architectures for Energy Storage Devices with High Areal and Volumetric Energy Density显示文摘Designing high-performance electrodes via 3D printing for advanced energy storage is appealing but remains challenging.In normal cases,light-weight carbonaceous materials harnessing excellent electrical conductivity have served as electrode candidates.However,they struggle with undermined areal and volumetric energy density of supercapacitor devices,thereby greatly impeding the practical applications.Herein,we demonstrate the in situ coupling of NiCoP bimetallic phosphide and Ti3C2 MXene to build up heavy NCPM electrodes affording tunable mass loading throughout 3D printing technology.The resolution of prints reaches 50μm and the thickness of device electrodes is ca.4 mm.Thus-printed electrode possessing robust open framework synergizes favorable capacitance of NiCoP and excellent conductivity of MXene,readily achieving a high areal and volumetric capacitance of 20 F cm^-2 and 137 F cm^-3 even at a high mass loading of^46.3 mg cm^-2.Accordingly,an asymmetric supercapacitor full cell assembled with 3D-printed NCPM as a positive electrode and 3D-printed activated carbon as a negative electrode harvests remarkable areal and volumetric energy density of 0.89 mWh cm^-2 and 2.2 mWh cm^-3,outperforming the most of state-of-the-art carbon-based supercapacitors.The present work is anticipated to offer a viable solution toward the customized construction of multifunctional architectures via 3D printing for high-energy-density energy storage systems. | Lianghao Yu Weiping Li Chaohui Wei Qifeng Yang Yuanlong Shao Jingyu Sun | 2020 | Nano-Micro Letters2020，12，10： | 1 |
| 18 | A new panel containing specific spermatogenesis markers to identify spermatogenic cells in nonobstructive azoospermia patients显示文摘Infertility is a severe problem that affects 10%-15% of couples worldwide, among which male infertility is a factor in ~50% of the cases [1]. Azoospermia, which is defined as the absence of sperm in at least two ejaculates, can be divided into two types: obstructive azoospermia (OA) and non-OA (NOA)[1]. OA patients have normal spermatogenesis and mature sperm in testes and can father a biological child through testicular sperm retrieval and intracytoplasmic sperm injection (ICSI)[2]. By contrast, NOA patients usually have various degrees of spermatogenesis impairment and can be faced with complicated assisted reproductive technology (ART) strategies to father a biological child [2]. The precise diagnosis of spermatogenesis in NOA patients is crucial for clinical decision making regarding ART. | Xinxi Zhao Yiqin Wang Meng Ma Wei Zhang Jiqiang Si Wei Wang Zhen Lin Gang Han Charlie Degui Chen Minghan Tong Yanping Kuang Qifeng Lyu | 2019 | Acta Biochimica et Biophysica Sinica2019，51，6： | 1 |
| 19 | The recovery of zinc from hot galvanizing slag in an anion-exchange membrane electrolysis reactor显示文摘 | Xiulian Ren Qifeng Wei Surong Hu Sijie Wei | 2010 | Journal of Hazardous Materials2010，，1： | 1 |
| 20 | Study of the Electro- deposition Conditionsof Metallic Manganese in An Electro- lytic Membrane Reactor显示文摘 | Wei Qifeng Ren Xiulian Du Jie | 2010 | Minerals Engineering2010，23，7： | 1 |
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