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| 1 | Precipitation seesaw phenomenon and its formation mechanism in the eastern and western parts of Northwest China during the flood season显示文摘Extending across three major plateaus,namely the Qinghai-Tibetan Plateau,the Inner Mongolia-Xinjiang Plateau and the Loess Plateau,Northwest China has the complex terrain and spatio-temporal climate variations,and is affected by the interactions among different circulation systems,such as the summer monsoon,the westerlies and the plateau monsoon.The understanding of the climate variability,as well as its characteristics and evolution mechanisms in this area has been limited so far.In this paper,the precipitation characteristics and mechanisms in the eastern and western parts of Northwest China during the flood season are compared and analyzed based on the data from 192 national meteorological observational sites in Northwest China in 1961-2016.The results show that,divided by the northern boundary of the East Asian summer monsoon,there are huge differences in the precipitation variation characteristics between the eastern and western parts.The inter-annual variations,interdecadal variations and total trends in the two parts all show a significant seesaw phenomenon.Moreover,it is found that the seesaw phenomenon of precipitation variation is closely related to the opposite variation between the East Asian summer monsoon index(MI)and the westerly circulation index(WI).In addition,the inverse variations on different time scales are only related to the contributions of precipitation at specific grades.Besides,in the two matching patterns of precipitation in the seesaw phenomenon,the middle and high latitudes are occupied by the'high-low-high'wave trains in the precipitation increases in the east of Northwest China(ENWC)and decreases in the west of Northwest China(WNWC)pattern,meaning precipitation increases in ENWC and decreases in WNWC.Whereas the opposite'low-high-low'wave trains at 500 hPa height are observed in the middle and high latitudes in the WH-EA pattern at 500 hPa height,meaning precipitation increases in WNWC and decreases in ENWC.Thus,the atmosphere circulation situation with two wave train types can support both the precipitation seesaw phenomenon and the opposite variation between MI and WI.Moreover,the seesaw phenomenon is shown to be related to the separate or joint effects of the South Asian High,ENSO and the plateau heating on the common but opposite effect on the summer monsoon and the westerlies,in which the South Asian High probably plays a more critical role.This study could deepen the scientific understanding of precipitation mechanisms and improve the weather forecast technology in Northwest China during the flood season. | Qiang ZHANG Jingjing LIN Weicheng LIU Lanying HAN | 2019 | Science China Earth Sciences2019，62，12： | 11 |
| 2 | New mass loss kinetic model for thermal decomposition of biomass显示文摘Based on non-isothermal experimental results for eight Chinese biomass species, a new kinetic model, named as the 損seudo bi-component separate-stage model (PBSM)? is developed in this note to describe the mass loss behavior of biomass thermal decomposition. This model gains an advantage over the commonly used 損seudo single-component overall model (PSOM)?and 損seudo multi-component overall model (PMOM)? By means of integral analysis it is indicated that the new model is suitable to describe the mass loss kinetics of wood and leaf samples under relatively low heating rates (e.g. 10℃/min, used in this work). | LIU Naian FAN Weicheng R.Dobashi LIN Qizhao | 2001 | Chinese Science Bulletin2001，46，16： | 6 |
| 3 | Efficient Implementation ofRFID Mutual Authentication Protocol 显示文摘 | Yujung Huang Weicheng Lin Hunglin Li | 2012 | IEEE TRANSACTIONS ONINDUSTRIAL ELECTRONICS2012，59，12： | 1 |
| 4 | Construction of Streptomyces lydicus A01 transformant with the chit33 gene from Trichoderma harzianum CECT2413 and its biocontrol effect on Fusaria显示文摘Streptomyces lydicus A01 resists many plant pathogens (including Fusarium spp.) by producing the antifungal agent natamycin, which binds to the ergosterol of fungal cell membranes and inhibits the growth of pathogens. Trichoderma harzianum CECT2413 is a widely-distributed soil fungus that antagonizes several plant fungal pathogens (including Fusarium spp.) by producing chi-tinase and degrading chitin, a major component of the fungal cell wall. This study attempted to enhance the biocontrol effect of S. lydicus A01 on Fusarium spp. by transforming the chitinase gene of Trichoderma. Chitinase and natamycin could act synergisti-cally on both the cell walls and cell membranes of pathogens. The 33-kD chitinase-encoding gene (chit33) was cloned and conju-gal-transformed from T. harzianum CECT2413 to S. lydicus A01, and then confirmed via polymerase chain reaction (PCR) assays. Subsequent analyses using the 3,5-dinitrosalicylic acid (DNS) method and ultraviolet spectrophotometry showed that compared with its wild type strain (WT), the S. lydicus A01 conjugal transformant (CT) with chit33 gene exhibited substantially higher chi-tinase activity and natamycin production. The resistance of S. lydicus A01-chit33 CT and WT to four Fusaria in crops and vegetables was tested via the cup-plate method. Compared with the WT, the conjugal transformant of S. lydicus A01 with chit33 gene from T. harzianum CECT2413 showed greatly increased biocontrol effect on fusarium disease. This study would be beneficial to the development of high-quality antifungal bio-agents for agricultural applications via the synergy between the previously non-existent and pre-existing functions achieved through heterogeneous gene transformation. | WU Qiong BAI LinQuan LIU WeiCheng LI YingYing LU CaiGe LI YaQian LIN ZhenYa WANG Meng XUE ChunSheng CHEN Jie | 2013 | Chinese Science Bulletin2013，58，26： | 1 |
| 5 | The co-administrating of recombinant porcine IL-2 could enhance protective immune responses to PRV inactivated vaccine in pigs显示文摘 | Lin Y Qigai H Xiaolan Y Weicheng B | 2005 | Vaccine2005，23，35： | 1 |
| 6 | Genetic Variants in Cyclooxygenase-2 : Expression and Risk of Gastric Cancer and Its Precursors in a Chinese Population显示文摘 | Fen Liu Kaifeng Pan Xuemei Zhang Yang Zhang Lian Zhang Junling Ma Caixuan Dong Lin Shen Jiyou Li Dajun Deng Dongxin Lin Weicheng You | 2006 | Gastroenterology2006，，7： | 1 |
| 7 | Potential use an Actinobacillus pleuropneumoniae double mutant strain Δ apxIIC Δ apxIVA as live vaccine that allows serological differentiation between vaccinated and infected animals显示文摘 | Jinlin Liu Xia Chen Liwen Lin Chen Tan Yan Chen Yi Guo Meilin Jin Aizhen Guo Weicheng Bei Huanchun Chen | 2007 | Vaccine2007，，44： | 1 |
| 8 | Construction and characterization of a live, attenuated apxIICA inactivation mutant of Actinobacillus pleuropneumoniae lacking a drug resistance marker显示文摘 | Weicheng Bei Qigai He Lin Yan Liurong Fang Yadi Tan Shaobo Xiao Rui Zhou Meilin Jin Aizhen Guo Jianqiang Lv Hongliang Huang Huanchun Chen | 2004 | FEMS Microbiology Letters2004，，1： | 1 |
| 9 | Calculating electron-phonon coupling matrix: Theory introduction,code development and preliminary application显示文摘Electron-phonon coupling(EPC) in bulk materials is an important effect in multifarious physical and chemical phenomena. It is the key to explaining the mechanisms for superconductivity, electronic transport, etc. The EPC matrix describes the coupling of the electronic eigenstates of the studied system under the perturbation of phonons. Although the EPC matrix is closely relevant to many fundamental physicochemical properties, it remains a challenge to calculate the EPC matrix precisely due to the high computational cost. In recent years, Giustino et al. developed the EPW method on open-source ab-initio software Quantum Espresso, which uses Wannier functions(WFs) to calculate EPC matrix. However, due to the limitation of their implementation,it is not possible yet to calculate the EPC matrix under some important computational conditions, e.g., for DFT+U and HSE calculation. Given the importance of these computational conditions(e.g., for transition metal oxides), we have developed our own implementation of EPC matrix calculation based on the domestic ab-initio software PWmat. Our code allows the DFT+U and HSE correction, so we can get a more accurate EPC matrix in the related problems. In this article, we will first review the formulae and elucidate how to calculate the EPC matrix by constructing WFs. Then we will introduce our code along with its workflow on PWmat and present our test results of two classical semiconductor systems Al As and Si, showing consistency with EPW. Next, the EPC matrix of Li Co O_(2), a classical cathode material for lithium-ion batteries, is calculated using different exchange correlation(XC) functionals including LDA, PBE, DFT+U and HSE. A comparison is provided for the related EPC matrix. It shows there could be a significant difference for the EPC matrix elements due to the use of different XC functionals.Our implementation thus opens the way for fast calculation of EPC for the important class of materials, like the transition metal oxides. | YE YaoKun WENG MouYi ZHANG WenTao LIN WeiCheng CHEN TaoWen PAN Feng ZHENG JiaXin WANG Lin-Wang | 2023 | Science China(Technological Sciences)2023，66，1： | 1 |
| 10 | The co-administrating of recombinant porcine IL-2 could enhance protective immune responses to PRV inactivated vaccine in pigs显示文摘 | Yan Lin He Qigai Yu Xiaolan Bei Weicheng Chen Huanchun | 2005 | Vaccine2005，，35： | 1 |
| 11 | Potential use an Actinobacillus pleuropneumoniae double mutant strain Δ apxIIC Δ apxIVA as live vaccine that allows serological differentiation between vaccinated and infected animals显示文摘 | Jinlin Liu Xia Chen Liwen Lin Chen Tan Yan Chen Yi Guo Meilin Jin Aizhen Guo Weicheng Bei Huanchun Chen | 2007 | Vaccine2007，，44： | 1 |
| 12 | Highly sensitive vector magnetic fiber sensor based on hyperbolic metamaterials显示文摘Hyperbolic metamaterials(HMMs) are novel artificial materials that excite the surface plasmon resonance(SPR) because of their unique hyperbolic dispersion properties. Herein, to the best of our knowledge, we propose the first HMM-based fiber SPR(HMM-SPR) sensor for vector magnetic detection. By selecting the composite materials and structural parameters of the HMM dispersion management, HMM-SPR sensors can achieve a high refractive index sensitivity of 14.43 μm/RIU. Vector magnetic field detection was performed with the HMM-SPR sensor encapsulated with a magnetic fluid. Compared with other ferrofluidbased magnetic field fiber sensors, the proposed sensor shows pronounced advantages in intensity and direction sensitivity of 1.307 nm/Oe and 7.116 nm/°, respectively. The sensor design approach presented in this paper provides an excellent demonstration of HMM-SPR sensors in various applications. | Shiqi Hu Junhao Liang Jiayao Chen Hongda Cheng Qianyu Lin Weicheng Shi Jinming Yuan Gui-Shi Liu Lei Chen Zhe Chen Norhana Arsad Yaofei Chen Yunhan Luo | 2022 | Science China(Physics,Mechanics & Astronomy)2022，65，11： | 0 |
| 13 | Tea domain transcription factor TEAD4 mitigatesTGF-β signaling and hepatocellular carcinomaprogression independently of YAP显示文摘Tea domain transcription factor 4 (TEAD4) plays a pivotal role in tissue development and homeostasis by interacting with Yesassociated protein (YAP) in response to Hippo signaling inactivation. TEAD4 and YAP can also cooperate with transforminggrowth factor-β (TGF-β)-activated Smad proteins to regulate gene transcription. Yet, it remains unclear whether TEAD4 playsa YAP-independent role in TGF-β signaling. Here, we unveil a novel tumor suppressive function of TEAD4 in liver cancer viamitigating TGF-β signaling. Ectopic TEAD4 inhibited TGF-β-induced signal transduction, Smad transcriptional activity, and targetgene transcription, consequently suppressing hepatocellular carcinoma cell proliferation and migration in vitro and xenografttumorgrowth in mice. Consistently, depletion of endogenous TEAD4 by siRNAs enhanced TGF-β signaling in cancer cells. Mechanistically,TEAD4 associates with receptor-regulated Smads (Smad2/3) and Smad4 in the nucleus, thereby impairing the binding of Smad2/3to the histone acetyltransferase p300. Intriguingly, these negative effects of TEAD4 on TGF-β/Smad signaling are independent ofYAP, as impairing the TEAD4–YAP interaction through point mutagenesis or depletion of YAP and/or its paralog TAZ has little effect.Together, these results unravel a novel function of TEAD4 in fine tuning TGF-β signaling and liver cancer progression in a YAPindependent manner. | Weicheng Luo Yi Li Yi Zeng Yining Li Minzhang Cheng Cheng Zhang Fei Li Yiqing Wu Chunhong Huang Xiaolong Yang Joachim Kremerskothen Jianmin Zhang Chunbo Zhang Shuo Tu Zhihua Li Zhijun Luo Zhenghong Lin Xiaohua Yan | 2023 | Journal of Molecular Cell Biology2023，15，2： | 0 |
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