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| 1 | Ultrafast and broadband photodetectors based on a perovskite/organic bulk heterojunction for large-dynamic-range imaging显示文摘Organic-inorganic hybrid perovskite(OIHP)photodetectors that simultaneously achieve an ultrafast response and high sensitivity in the near-infrared(NIR)region are prerequisites for expanding current monitoring,imaging,and optical communication capbilities.Herein,we demonstrate photodetectors constructed by OIHP and an organic bulk heterojunction(BHJ)consisting of a low-bandgap nonfullerene and polymer,which achieve broadband response spectra up to 1μm with a highest external quantum efficiency of approximately 54%at 850 nm,an ultrafast response speed of 5.6 ns and a linear dynamic range(LDR)of 191 dB.High sensitivity,ultrafast speed and a large LDR are preeminent prerequisites for the practical application of photodetectors.Encouragingly,due to the high-dynamicrange imaging capacity,high-quality visible-NIR actual imaging is achieved by employing the OIHP photodetectors.We believe that state-of-the-art OIHP photodetectors can accelerate the translation of solution-processed photodetector applications from the laboratory to the imaging market. | Chenglong Li Hailu Wang Fang Wang Tengfei Li Mengjian Xu Hao Wang Zhen Wang Xiaowei Zhan Weida Hu Liang Shen | 2020 | Light(Science & Applications)2020，9，1： | 13 |
| 2 | Sequential fate-switches in stem-like cells drive the tumorigenic trajectory from human neural stem cells to malignant glioma显示文摘Glioblastoma(GBM)is an incurable and highly heterogeneous brain tumor,originating from human neural stem/progenitor cells(hNSCs/hNPCs)years ahead of diagnosis.Despite extensive efforts to characterize hNSCs and end-stage GBM at bulk and single-cell levels,the de novo gliomagenic path from hNSCs is largely unknown due to technical difficulties in early-stage sampling and preclinical modeling.Here,we established two highly penetrant hNSC-derived malignant glioma models,which resemble the histopathology and transcriptional heterogeneity of human GBM.Integrating time-series analyses of whole-exome sequencing,bulk and single-cell RNA-seq,we reconstructed gliomagenic trajectories,and identified a persistent NSC-like population at all stages of tumorigenesis.Through trajectory analyses and lineage tracing,we showed that tumor progression is primarily driven by multi-step transcriptional reprogramming and fate-switches in the NSC-like cells,which sequentially generate malignant heterogeneity and induce tumor phenotype transitions.We further uncovered stage-specific oncogenic cascades,and among the candidate genes we functionally validated C1QL1 as a new glioma-promoting factor.Importantly,the neurogenic-to-gliogenic switch in NSC-like cells marks an early stage characterized by a burst of oncogenic alterations,during which transient AP-1 inhibition is sufficient to inhibit gliomagenesis.Together,our results reveal previously undercharacterized molecular dynamics and fate choices driving de novo gliomagenesis from hNSCs,and provide a blueprint for potential early-stage treatment/diagnosis for GBM. | Xiaofei Wang Ran Zhou Yanzhen Xiong Lingling Zhou Xiang Yan Manli Wang Fan Li Chuanxing Xie Yiming Zhang Zongyao Huang Chaoqiong Ding Kaidou Shi Weida Li Yu Liu Zhongwei Cao Zhen-Ning Zhang Shengtao Zhou Chong Chen Yan Zhang Lu Chen Yuan Wang | 2021 | Cell Research2021，31，6： | 8 |
| 3 | Laser direct writing and characterizations of flexible piezoresistive sensors with microstructures显示文摘Functional materials with high viscosity and solid materials have received more and more attentions in flexible pressure sensors,which are inadequate in the most used molding method.Herein,laser direct writing(LDW)method is proposed to fabricate flexible piezoresistive sensors with microstructures on PDMS/MWCNTs composites with an 8%MWCNTs mass fraction.By controlling laser energy,microstructures with different geometries can be obtained,which significantly impacts the performances of the sensors.Subsequently,curved microcones with excellent performance are fabricated under parameters of f=40 kHz and v=150 mm·s^(-1).The sensor exhibits continuous multi-linear sensitivity,ultrahigh original sensitivity of 21.80%kPa^(-1),wide detection range of over 20 kPa,response/recovery time of~100 ms and good cycle stability for more than 1000 times.Besides,obvious resistance variation can be observed when tiny pressure(a peanut of 30 Pa)is applied.Finally,the flexible piezoresistive sensor can be applied for LED brightness controlling,pulse detection and voice recognition. | Chenying Zhang Wei Zhou Da Geng Cheng Bai Weida Li Songyue Chen Tao Luo Lifeng Qin Yu Xie | 2021 | Opto-Electronic Advances2021，4，4： | 7 |
| 4 | Effect of ZrO_2 Content on the Properties of Diamond Grinding Wheel Vitrified Bond显示文摘The effect of ZrO2 content on the performance of vitrified bond was discussed. The results showed that when the ZrO2 content was less than 2 mol%, Zr4+ could enter into the glassy network as mending nets and agglomeration composition. In this case, with the increasing of ZrO2, the vitrified bond's bending strength increased and the expansion coefficient decreased. It was also found that the wetting angle between the vitrified bond and diamond got small because Zr4+ was enriched on diamond surface. When ZrO2 content was more than 2 mol%, a part of ZrO2 existing in vitrified bond as ZrO2 particles played the role in nucleating agents and promoting the separation of spodumene. When ZrO2 content was 3 mol%, the bending strength of the vitrified bond reached its maximum of 128 MPa and the wetting angle with the diamond reached its minimum of 37.6°. | 刘小磐 QIAO Ang WAN Long HU Weida SONG Dongdong LI Zheng YIN Zhongjie 潘瑞琨 | 2014 | Journal of Wuhan University of Technology(Materials Science)2014，29，1： | 7 |
| 5 | Analysis Method and Principle of Dual-mode Electro-mechanical Variable Transmission Program显示文摘Automotive industry,as an important pillar of the national economy,has been rapidly developing in recent years.But proplems such as energy comsumption and environmental pollution are posed at the same time.Electro-mechanical variable transmission system is considered one of avilable workarounds.It is brought forward a kind of design methods of dual-mode electro-mechanical variable transmission system rotational speed characteristics and dual-mode drive diagrams.With the motor operating behavior of running in four quadrants and the speed characteristics of the simple internal and external meshing single planetary gear train,four kinds of dual-mode electro-mechanical transmission system scheme are designed.And the velocity,torque and power characteristics of one of the programs are analyzed.The magnitude of the electric split-flow power is an important factor which influences the system performance,so in the parameters matching design,it needs to reduce the power needs under the first mode of the motor.The motor,output rotational speed range and the position of the mode switching point have relationships with the characteristics design of the planetary gear set.The analysis method is to provide a reference for hybrid vehicles' design.As the involved rotational speed and torque relationships are the natural contact of every part of transmission system,a theory basis of system program and performance analysis is provided. | LI Hongcai YAN Qingdong XIANG Changle WANG Weida | 2012 | Chinese Journal of Mechanical Engineering2012，25，3： | 6 |
| 6 | Primary structure of helix C to helix G of a new retinal protein in H.sp.xz515显示文摘The gene fragment encoding the retinal protein from helix C to helix G in a new strain of halobacteria, H.sp.xz515 has been amplified by PCR method. The nucleotide sequence of this fragment has been determined. The deduced amino acid sequence has been compared with halobium br and other two br-like proteins, ar-1 and ar-2. Results show that those amino acid residues in br, essential for proton pumping and binding to retinal, are conserved. The residue M145 in br may be important for isomerization reaction of retinal. | Hui Wang Shuxuan Zhan Qingan Sun Deqiang Xu Wei Zhao Weida Huang Qingguo Li | 2000 | Chinese Science Bulletin2000，45，12： | 5 |
| 7 | Progress and challenges in blocked impurity band infrared detectors for space-based astronomy显示文摘Astronomical detection at infrared wavelengths is crucial in astrophysics due to the critical information in this wavelength range.Blocked impurity band(BIB) infrared detectors are desirable for space-based astronomical observation due to their broad response range, low dark currents, high quantum efficiencies, and excellent radiation resistance. In this review, typical BIB device structures and device physics development are first introduced. Subsequently, we discuss progress in Si-based BIB detectors with different doping types and emphasize their applications in space-based infrared detection. Additionally, we discuss recent efforts on pixel performance optimization, response extension, and higher operating temperature devices. Finally,we conclude by proposing the challenges and perspectives of BIB detectors with improved detection performances. | Yunlong Xiao He Zhu Ke Deng Peng Wang Qing Li Ting He Tao Zhang Jinshui Miao Ning Li Wei Lu Ning Dai Weida Hu | 2022 | Science China(Physics,Mechanics & Astronomy)2022，65，8： | 4 |
| 8 | Pristine PN junction toward atomic layer devices显示文摘In semiconductor manufacturing,PN junction is formed by introducing dopants to activate neighboring electron and hole conductance.To avoid structural distortion and failure,it generally requires the foreign dopants localize in the designated micro-areas.This,however,is challenging due to an inevitable interdiffusion process.Here we report a brand-new junction architecture,called'layer PN junction',that might break through such limit and help redefine the semiconductor device architecture.Different from all existing semiconductors,we find that a variety of van der Waals materials are doping themselves from n-to p-type conductance with an increasing/decreasing layer-number.It means the capability of constructing homogeneous PN junctions in monolayers'dimension/precision,with record high rectification-ratio(>10^(5))and low cut-off current(<1 pA).More importantly,it spawns intriguing functionalities,like gate-switchable-rectification and noise-signal decoupled avalanching.Findings disclosed here might open up a path to develop novel nanodevice applications,where the geometrical size becomes the only critical factor in tuning charge-carrier distribution and thus functionality. | Hui Xia Man Luo Wenjing Wang Hailu Wang Tianxin Li Zhen Wang Hangyu Xu Yue Chen Yong Zhou Fang Wang Runzhang Xie Peng Wang Weida Hu Wei Lu | 2022 | Light(Science & Applications)2022，11，7： | 4 |
| 9 | Oral vaccination of mice against rodent malaria with recombinant Lactococcus lactis expressing MSP-1_(19)显示文摘瞄准:构造 recombinant Lactococcus 乳酸作为对疟疾的口头的交货种痘。方法:变形体 yoelii 265-BY 的 MSP1 (MSP-1 (19 )) 的 C 终端 19-ku 碎片在 L 被表示。乳酸是并且 recombinant L。乳酸是予 BALB/c 和 C57BL/6 老鼠口头上地被以。在在 4 wk 以内的七间隔种痘以后,老鼠与 P 被质问。红细胞舞台的 yoelii 265-BY 寄生虫。recombinant L 的保护的功效。乳酸被评估。结果:分别地,在为 BALB/c 和 C57BL/6 鼠标的实验组的一般水准的山峰 parasitemias 是 0.8+/-0.4% 和 20.8+/-26.5% ,他们的控制组的那些分别地是 12.0+/-0.8% 和 60.8+/-9.6% 。任何一个都没在实验期间死于在试验性的组和控制组的 BALB/c 老鼠。然而,在控制组的所有 C57BL/6 鼠标在 23 d 和熬过很好的所有种牛痘的鼠标以内死了。结论:结果暗示 recombinant L 的潜力。乳酸作为对疟疾的口头的交货种痘。 | Zhi-Hong Zhang Pei-Hong Jiang Ning-Jun Li Mi Shi Weida Huang | 2005 | World Journal of Gastroenterology2005，11，44： | 4 |
| 10 | Tinea faciei in a newborn due toTrichophyton tonsurans显示文摘We report here the first case of neonatal tinea faciei caused by Trichophyton tonsurans in China's Mainland.The mother of the infant had tinea corpris and tinea capitis while the father had tinea incongnito.The infections in the parents were mycologically confirmed to be due to Trichophyton tonsurans.Ttinea faciei in the infant was cured after two-week topical use of amorolfine cream.The mother ceased breastfeeding and took oral terbinafine for 4 weeks.No recurrence was observed in the infant during 12 months of follow-up. | Meihua Fu Yiping Ge Wei Chen Suying Feng Xiaodong She Xiaofang Li Weida Liu | 2013 | The Journal of Biomedical Research2013，27，1： | 3 |
| 11 | Shrinkage Characteristics of Lime Concretion Black Soil as Affected by Biochar Amendment显示文摘Studies have reported that biochar is a sustainable amendment that improves the chemical and physical properties of soil.In this study,an incubation experiment was conducted to investigate the effects of different application rates of biochar on the cracking pattern and shrinkage characteristics of lime concretion black soil after three wetting and drying cycles.Biochar derived from the corn straw and peanut shell mixture was applied to the soil at rates of 0,50,100,and 150 g kg^(-1)dry weight,representing the treatments T_(0),T_(50),T_(100),and T_(150),respectively.During the wetting and drying cycles,the cracking pattern and shrinkage characteristics of the unamended and amended soil samples were recorded.Application of biochar significantly increased soil organic carbon content in the samples.During soil desiccation,biochar significantly reduced the rate of water loss.Cracks propagated slowly and stopped due to the relatively higher water content in the soil applied with biochar.The cracking area density(ρ_c),equivalent width,fractal dimension,and cracking connectivity index decreased during the drying process with increasing application rate of biochar.Theρ_(c )value of the T_(50),T_(100),and T_(150) treatments decreased by 33.6%,52.1%,and 56.9%,respectively,after three wetting and drying cycles,whereas the T_(0) treatment exhibited a marginal change.The coefficient of linear extensibility,an index used to describe onedimentional shrinkage,of the unamended soil sample(T_(0))was approximately 0.23.Application of 100 and 150 g kg^(-1)biochar to the soil significantly reduced the shrinkage capacity by 41.45%and 45.54%,respectively.The slope of the shrinkage characteristics curve,which indicates the ralationship between soil void ratio and moisture ratio,decreased with increase in the application rate of biochar.Furthermore,compared with the T_(0) treatment,the proportional shrinkage zone of the shrinkage characteristic curve of the T_(50),T_(100),and T_(150) treatments decreased by 5.8%,13.1%,and 12.1%,respectively.Differences were not observed in the moisture ratio at the maximum curvature of the shrinkage characteristic curve among the treatments.The results indicate that biochar can alter the cracking pattern and shrinkage characteristics of lime concretion black soil.However,the effects of biochar on the shrinkage of lime concretion black soil are dependent on the number of wetting and drying cycles. | WEI Cuilan GAO Weida William Richard WHALLEY LI Baoguo | 2018 | Pedosphere2018，28，5： | 3 |
| 12 | Enhanced U(Ⅵ) bioreduction by alginate-immobilized uranium-reducing bacteria in the presence of carbon nanotubes and anthraquinone-2,6-disulfonate显示文摘Uranium-reducing bacteria were immobilized with sodium alginate, anthraquinone-2,6-disulfonate(AQDS), and carbon nanotubes(CNTs). The effects of different AQDS-CNTs contents, U(Ⅳ) concentrations, and metal ions on U(Ⅳ) reduction by immobilized beads were examined. Over 97.5% U(Ⅵ)(20 mg/L) was removed in 8 hr when the beads were added to 0.7% AQDS-CNTs, which was higher than that without AQDS-CNTs. This result may be attributed to the enhanced electron transfer by AQDS and CNTs. The reduction of U(Ⅵ) occurred at initial U(Ⅵ) concentrations of 10 to 100 mg/L and increased with increasing AQDS-CNT content from 0.1% to 1%. The presence of Fe(Ⅲ), Cu(Ⅱ) and Mn(Ⅱ)slightly increased U(Ⅵ) reduction, whereas Cr(Ⅵ), Ni(Ⅱ), Pb(Ⅱ), and Zn(Ⅱ) significantly inhibited U(Ⅵ) reduction. After eight successive incubation-washing cycles or 8 hr of retention time(HRT) for 48 hr of continuous operation, the removal efficiency of uranium was above 90% and 92%, respectively. The results indicate that the AQDS-CNT/AL/cell beads are suitable for the treatment of uranium-containing wastewaters. | Weida Wang Yali Feng Xinhua Tang Haoran Li Zhuwei Du Aifei Yi Xu Zhang | 2015 | Journal of Environmental Sciences2015，27，5： | 3 |
| 13 | Preparation of Ti-based Yb-doped SnO_(2)-RuO_(2) electrode and electrochemical oxidation treatment of coking wastewater显示文摘In this study,the Ti/SnO_(2)-RuO_(2) electrodes with different Yb contents were prepared by sol-gel method and thermal decomposition method,and the surface morphology and crystal structure of the electrodes were characterized by scanning electron microscopy(SEM),atomic force microscopy(AFM) and X-ray diffraction(XRD),the electrochemical properties of the electrodes were tested by linear sweep voltammetry(LSV) and cyclic voltammetry(CV).The electrochemical oxidation device was constructed with Yb-doped Ti/SnO_(2)-RuO_(2) electrode as the anode and titanium plate as the cathode,and the electrochemical oxidation effect and product changes of the anode on co king wastewater were investigated.The results show that the surface of the electrode is flat with high crystallinity of SnO_(2) and RuO_(2) crystals at1.5% Yb doping,and the LSV and CV curves indicate that the Yb doping of 1.5% increases the oxygen precipitation potential and electrocatalytic oxidation activity of the electrode.When the electrode with Yb doping of 1.5% is the anode with current density of 10 mA/cm^(2) electrochemical oxidation time of 30 min,the electrode can remove chemical oxygen demand(COD) up to 85.06%,total organic carbon(TOC) up to 60.59% and UV_(254) from 1.594 to 0.507 for coking wastewater.Gas chromatography(GC-MS),UV-vis and three-dimensional fluorescence results of coking wastewater before and after treatment show that large toxic substances in coking wastewater are degraded to low toxic organic substances,and most soluble organic substances are degraded and transformed.This study provides the possibility of basic research for the engineering practice of electrochemical oxidation for the treatment of coking wastewater. | Weida Wang Ke Wang Wenting Hao Tingting Zhang Yijie Liu Linghong Yu Weiping Li | 2022 | Journal of Rare Earths2022，40，5： | 2 |
| 14 | The association of grip strength with cardiovascular diseases and all-cause mortality in people with hypertension:Findings from the Prospective Urban Rural Epidemiology China Study显示文摘Background:Both hypertension and grip strength(GS)are predictors of mortality and cardiovascular disease(CVD),but whether these risk factors interact to affect CVD and all-cause mortality is unknown.This study sought to investigate the associations of GS with the risk of major CVD incidence,CVD mortality,and all-cause mortality in patients with hypertension.Methods:GS was measured using a Jamar dynamometer(Sammons Preston,Bolingbrook,IL,USA)in participants aged 3570 years from 12 provinces included in the Prospective Urban Rural Epidemiology China Study.Cox frailty proportional hazards models were used to examine the associations of GS and hypertension and the outcomes of all-cause mortality and CVD incidence/mortality.Results:Among 39,862 participants included in this study,15,964 reported having hypertension,and 9095 had high GS at baseline.After a median follow-up of 8.9 years(interquartile range,6.79.9 years),1822 participants developed major CVD,and 1250 deaths occurred(388 as a result of CVD).Compared with normotensive participants with high GS,hypertensive patients with high GS had a higher risk of major CVD incidence(hazard ratio(HR)=2.39;95%confidence interval(95%CI):1.863.06;p<0.001)or CVD mortality(HR=3.11;95%CI:1.596.06;p<0.001)but did not have a significantly increased risk of all-cause mortality(HR=1.24;95%CI:0.921.68;p=0.159).These risks were further increased if hypertensive participants whose GS level was low(major CVD incidence,HR=3.31,95%CI:2.604.22,p<0.001;CVD mortality,HR=4.99,95%CI:2.649.43,p<0.001;and all-cause mortality,HR=1.93,95%CI:1.472.53,p<0.001).Conclusion:The present study demonstrates that low GS is associated with the highest risk of major CVD incidence,CVD mortality,and all-cause mortality among hypertensive patients.High levels of GS appear to mitigate long-term mortality risk among hypertensive patients. | Weida Liu Darryl P Leong Bo Hu Lap AhTse Sumathy Rangarajan Yang Wang Chuangshi Wang Fanghong Lu Yindong Li Salim Yusuf Lisheng Liu Wei Li | 2021 | Journal of Sport and Health Science2021，10，6： | 2 |
| 15 | Wavelet Support vector machine 显示文摘 | Zhang Li Zhou Weida Jiao Licheng | 2004 | IEEE Transaction on Sysyems man and Cybernetics-part B: cybernetics2004，34，1： | 1 |
| 16 | Stoichiometric effect on electrical and near-infrared photodetection properties of full-composition-range GaAs1−xSbx nanowires显示文摘As one of the most important narrow bandgap ternary semiconductors, GaAs1−xSbx nanowires (NWs) have attracted extensive attention recently, due to the superior hole mobility and the tunable bandgap, which covers the whole near-infrared (NIR) region, for technological applications in next-generation high-performance electronics and NIR photodetection. However, it is still a challenge to the synthesis of high-quality GaAs1−xSbx NWs across the entire range of composition, resulting in the lack of correlation investigation among stoichiometry, microstructure, electronics, and NIR photodetection. Here, we demonstrate the success growth of high-quality GaAs1−xSbx NWs with full composition range by adopting a simple and low-cost surfactant-assisted solid source chemical vapor deposition method. All of the as-prepared NWs are uniform, smooth, and straight, without any phase segregation in all stoichiometric compositions. The lattice constants of each NW composition have been well correlated with the chemical stoichiometry and confirmed by high-resolution transmission electron microscopy, X-ray diffraction, and Raman spectrum. Moreover, with the increase of Sb concentration, the hole mobility of the as-fabricated field-effect-transistors and the responsivity and detectivity of the as-fabricated NIR photodetectors increase accordingly. All the results suggest a careful stoichiometric design is required for achieving optimal NW device performances. | Jiamin Sun Mingming Han Meng Peng Lei Zhang Dong Liu Chengcheng Miao Jiafu Ye Zhiyong Pang Longbing He Hailu Wang Qing Li Peng Wang Lin Wang Xiaoshuang Chen Chongxin Shan Litao Sun Weida Hu Zai-xing Yang | 2021 | Nano Research2021，14，11： | 1 |
| 17 | [Corrigendum] Cidan inhibits liver cancer cell growth by reducing COX-2and VEGF expression and cell cycle arrest显示文摘 | Nan Li Donghai Zheng Jie Xue Weixing Guo Jie Shi Juxian Sun Chongde Lu Weida Zheng Mengchao Wu Shuqun Cheng | 2015 | Experimental and Therapeutic Medicine2015，，4： | 1 |
| 18 | Hidden space supprt vector machines显示文摘 | Zhang Li Zhou Weida Jiao Licheng | 2004 | IEEE Transactions on Neural Networks2004，15，6： | 1 |
| 19 | Wavelet Support Vector Machine显示文摘 | Li Zhang Weida Zhou Licheng Jiao | 2004 | IEEE TRANSACTIONS ON SYSTEMS MAN AND CYBERNETICS-PART B:CYBERNETICS2004，34，1： | 1 |
| 20 | Resveratrol ameliorates subacute intestinal ischemia-reperfusion injury显示文摘 | WenPeng Dong FanFan Li ZhiGuo Pan ShenXi Liu Hao Yu XianYue Wang ShengHui Bi WeiDa Zhang | 2013 | Journal of Surgical Research2013，，： | 1 |
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