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| 1 | Porous CuO nanowires as the anode of rechargeable Na-ion batteries显示文摘 | Lijiang Wang Kai Zhang Zhe Hu Wenchao Duan Fangyi Cheng Jun Chen | 2014 | Nano Research2014，7，2： | 21 |
| 2 | Internet of Vehicles in Big Data Era显示文摘As the rapid development of automotive telematics,modern vehicles are expected to be connected through heterogeneous radio access technologies and are able to exchange massive information with their surrounding environment. By significantly expanding the network scale and conducting both real-time and long-term information processing, the traditional Vehicular AdHoc Networks(VANETs) are evolving to the Internet of Vehicles(Io V), which promises efficient and intelligent prospect for the future transportation system. On the other hand, vehicles are not only consuming but also generating a huge amount and enormous types of data, which is referred to as Big Data. In this article, we first investigate the relationship between Io V and big data in vehicular environment, mainly on how Io V supports the transmission, storage, computing of the big data, and how Io V benefits from big data in terms of Io V characterization,performance evaluation and big data assisted communication protocol design. We then investigate the application of Io V big data in autonomous vehicles. Finally, the emerging issues of the big data enabled Io V are discussed. | Wenchao Xu Haibo Zhou Nan Cheng Feng Lyu Weisen Shi Jiayin Chen Xuemin (Sherman) Shen | 2018 | IEEE/CAA Journal of Automatica Sinica2018，5，1： | 19 |
| 3 | Coinfection with influenza A virus enhances SARS-CoV-2 infectivity显示文摘The upcoming flu season in the Northern Hemisphere merging with the current COVID-19 pandemic raises a potentially severe threat to public health.Through experimental coinfection with influenza A virus(IAV)and either pseudotyped or live SARS-CoV-2 virus,we found that IAV preinfection significantly promoted the infectivity of SARS-CoV-2 in a broad range of cell types.Remarkably,in vivo,increased SARS-CoV-2 viral load and more severe lung damage were observed in mice coinfected with IAV.Moreover,such enhancement of SARS-CoV-2 infectivity was not observed with several other respiratory viruses,likely due to a unique feature of IAV to elevate ACE2 expression.This study illustrates that IAV has a unique ability to aggravate SARS-CoV-2 infection,and thus,prevention of IAV infection is of great significance during the COVID-19 pandemic. | Lei Bai Yongliang Zhao Jiazhen Dong Simeng Liang Ming Guo Xinjin Liu Xin Wang Zhixiang Huang Xiaoyi Sun Zhen Zhang Lianghui Dong Qianyun Liu Yucheng Zheng Danping Niu Min Xiang Kun Song Jiajie Ye Wenchao Zheng Zhidong Tang Mingliang Tang Yu Zhou Chao Shen Li Zhou Yu Chen Huan Yan Ke Lan Ke Xu | 2021 | Cell Research2021，31，4： | 16 |
| 4 | On comparison of modified ADRCs for nonlinear uncertain systems with time delay显示文摘To tackle systems with both uncertainties and time delays, several modified active disturbance rejection control(ADRC) methods, including delayed designed ADRC(DD-ADRC), polynomial based predictive ADRC(PP-ADRC), Smith predictor based ADRC(SP-ADRC) and predictor observer based ADRC(PO-ADRC), have been proposed in the past years. This paper is aimed at rigorously investigating the performance of these modified ADRCs, such that the improvements of each method can be demonstrated.The capability to tackle time delay, the necessity of stable open loop and the performance of rejecting uncertainties for these methods are fully studied and compared. It is proven that large time delay cannot be tolerated for the stability of the closed-loop systems based on DD-ADRC and PP-ADRC. Moreover, stable open loop is shown to be necessary for stabilizing the closed-loop systems based on SP-ADRC. Furthermore,the performance of rejecting the 'total disturbance' at low frequency for these modified ADRCs is evaluated and quantitatively discussed. Finally, the simulations of a boiler turbine system illustrate the theoretical results. | Sen CHEN Wenchao XUE Sheng ZHONG Yi HUANG | 2018 | Science China(Information Sciences)2018，61，7： | 16 |
| 5 | PepperHub, an Informatics Hub for the Chili Pepper Research Community显示文摘 | Feng Liu Huiyang Vu Yingtian Deng Jingyuan Zheng Minglei Liu Lijun Ou Bozhi Yang Xiongze Dai Yanqing Ma Shengyu Feng Shuang He Xuefeng Li Zhuqing Zhang Wenchao Chen Shudong Zhou Rong Chen Minmin Liu Sha Yang Ruimin Wei Huadong Li Feng Li Bo Ouyang Xuexiao Zou | 2017 | Molecular Plant2017，10，8： | 13 |
| 6 | Analysis on gust factor of tropical cyclone strong wind over different underlying surfaces显示文摘Based on one year gradient wind data and the wind data of a strong typhoon observed by three meteorological towers located on the coast and at the inshore sea,the underlying surfaces of the meteorological towers were classified and the roughness lengths were calculated quantitatively.On the basis of strong wind characteristic representative assessment and sample selection on the wind data of strong typhoon Hagupit,the gust factor variation characteristics of tropical cyclones under different underlying surfaces were analyzed.The observed fact and variation rule were found as follows:1) The roughness lengths under neutral atmospheric condition which were calculated using logarithmic wind profile fitting based on the observation data can describe the slight change of the underlying surface objectively.2) The gust factor of strong typhoon wind didn't have variation trends with wind speed.But the variation amplitude of the gust factor was rather large over rough underlying surface which had pronounced effect on the numerical design of structural engineering.3) The variation of the gust factor with height satisfied power law or logarithmic law.The power law fitting was more suitable for smooth underlying surface while the logarithmic fitting was better over rough underlying surface.4) The observation data also suggested that the relationship between gust factor and roughness length can be described by power or linear equation.5) The gust factor observed in this typhoon case was different from the gust factor recommended by WMO:The gust factor of the offshore wind came from rough underlying surface was higher than the value recommended by WMO while the gust factor of the onshore wind came from smooth underlying surface is less than the WMO recommended value. | CHEN WenChao SONG LiLi ZHI ShiQun HUANG HaoHui QIN Peng | 2011 | Science China(Technological Sciences)2011，54，10： | 7 |
| 7 | Effect of quadratic pressure gradient term on a one-dimensional moving boundary problem based on modified Darcy's law显示文摘A relatively high formation pressure gradient can exist in seepage flow in low-permeable porous media with a threshold pressure gradient, and a significant error may then be caused in the model computation by neglecting the quadratic pressure gradient term in the governing equations.Based on these concerns, in consideration of the quadratic pressure gradient term, a basic moving boundary model is constructed for a one-dimensional seepage flow problem with a threshold pressure gradient. Owing to a strong nonlinearity and the existing moving boundary in the mathematical model,a corresponding numerical solution method is presented.First, a spatial coordinate transformation method is adopted in order to transform the system of partial differential equations with moving boundary conditions into a closed system with fixed boundary conditions; then the solution can be stably numerically obtained by a fully implicit finite-difference method. The validity of the numerical method is verified by a published exact analytical solution. Furthermore, to compare with Darcy's flow problem, the exact analytical solution for the case of Darcy's flow considering the quadratic pressure gradient term is also derived by an inverse Laplace transform.A comparison of these model solutions leads to the conclusion that such moving boundary problems must incorporatethe quadratic pressure gradient term in their governing equations; the sensitive effects of the quadratic pressure gradient term tend to diminish, with the dimensionless threshold pressure gradient increasing for the one-dimensional problem. | Wenchao Liu Jun Yao Zhangxin Chen Yuewu Liu | 2016 | Acta Mechanica Sinica2016，32，1： | 7 |
| 8 | Influence of physiological and environmental factors on the diurnal variation in emissions of biogenic volatile compounds from Pinus tabuliformis显示文摘Biological volatile organic compounds(BVOCs) have a large influence on atmospheric environmental quality, climate change and the carbon cycle. This study assesses the composition and diurnal variation in emission rates of BVOCs from Pinus tabuliformis, using an enclosure technique. Environmental parameters(temperature and light intensity) and physiological parameters(net photosynthetic rate, P_n; stomatal conductance, g_s; intercellular CO_2 concentration, C_i; and transpiration rate, T_r) that may affect emission behavior were continuously monitored. The 10 most abundant compound groups emitted by P. tabuliformis were classified by gas chromatography–mass spectrometry. The dominant monoterpenoid compounds emitted were α-pinene, β-myrcene, α-farnesene and limonene. The diurnal emission rate of BVOCs changed with temperature and light intensity, with dynamic analysis of BVOCs emissions revealing that their emission rates were more affected by temperature than light. The variation in monoterpene emission rates was consistent with estimates of P_n, g_s and T_r. Basal emission rates(at 30 °C,) of the main BVOCs ranged from 0.006 to 0.273 μg^(-1)/(hr g),while the basal ER standardization coefficients ranged from 0.049 to 0.144 °C^(-1). Overall, these results provide a detailed reference for the effective selection and configuration of tree species to effectively prevent and control atmospheric pollution. | Jungang Chen Huaxing Bi Xinxiao Yu Yanlin Fu Wenchao Liao | 2019 | Journal of Environmental Sciences2019，31，7： | 7 |
| 9 | Expression of the DNA-repair protein XRCC1 and DNA-repair enzyme Ku70 mRNA in the rat cerebral cortex following global cerebral ischemia/reperfusion Is this correlated with neuroprotective effects of theanine?显示文摘BACKGROUND: Numerous studies have shown that apoptosis, caused by cerebral ischemia/reperfusion injury, is a dynamic evolving process that occurs in a time-dependent fashion. Non-apoptotic cells can result in apoptosis, with a prolonged reperfusion period and an accumulation of DNA damage. Recent studies have indicated that theanine has a protective effect on the brain. Nonetheless, there is no research relating to whether theanine is neuroprotective following brain injury. OBJECTIVE: To investigate the effects of theanine on apoptosis in the cerebral cortex and mRNA expression of the DNA repair protein, XRCC1, and DNA repair enzyme, Ku70, at various time points following global cerebral ischemia/reperfusion in rats. DESIGN, TIME AND SETTING: A randomized, controlled animal study was performed at the Pharmacological Laboratory of Animal Experimental Center of Xi'an Jiaotong University, China, from April to October 2007. MATERIALS: Theanine (Wuhan Remote Technology Co., Ltd., China), XRCC1, Ku70 and GAPDH primers (Shanghai Sangon Biological Engineering Technology & Services Co., Ltd., China) were used in this study. METHODS: A total of 108 healthy, male Sprague Dawley rats were randomly divided into sham operation, ischemia/reperfusion and theanine groups. Each group was further divided into 6 sub- groups, with six rats in each, according to reperfusion time (2, 6, 12, 24, 48 and 72 hours). Rat models of global cerebral ischemia/reperfusion were established by the four-vessel occlusion method. Theanine (1 000 mg/kg) was injected into the caudal vein of rats in the theanine group immediately after surgery. Saline (4 mL/kg) was used in the sham operation and ischemia/reperfusion groups. The same dose was administered every 24 hours. MAIN OUTCOME MEASURES: Flow cytometry was employed to determine apoptosis of cerebral cortical neurons. Real-time reverse transcription-polymerase chain reaction was applied to quantify the expression of XRCC1 and Ku70 mRNA in the cerebral cortex. RESULTS: The apoptotic rate in the ischemia/reperfusion group was significantly greater compared with the sham operation group at various time points (P < 0.05). The apoptotic rate in the theanine group was significantly diminished compared with the ischemia/reperfusion group, but significantly increased compared with the sham operation group at 6, 12, 24, 48 and 72 hours (P < 0.05). Ex- pression of XRCC1 and Ku70 mRNA was significantly decreased in the ischemia/reperfusion group compared with the sham operation group at 2, 6, 12, 24, 48 and 72 hours (P < 0.05). The relative expression of XRCC1 mRNA in the theanine group was significantly increased compared with the ischemia/reperfusion group, but significantly reduced compared with the sham operation group at 6, 12, 24, 48 and 72 hours (P < 0.05). The relative expression of Ku70 mRNA was significantly lower in the theanine group compared with the sham operation group at 2, 6 and 12 hours (P < 0.05) and significantly greater than the ischemia/reperfusion group at 6, 12, 24, 48 and 72 hours (P < 0.05). CONCLUSION: The apoptotic rate in rats following global cerebral ischemia/reperfusion injury reaches a peak at 24 hours after reperfusion; however, the levels of DNA repair protein began to decrease after only 2 hours of reperfusion. Theanine antagonizes the decrease in XRCC1 and Ku70 mRNA expression in the rat cerebral cortex during global cerebral ischemia/reperfusion injury. | Rongliang Xue Wenchao Chen Ning Wang Shasha Li | 2010 | Neural Regeneration Research2010，5，1： | 5 |
| 10 | A cryptic inhibitor of cytokinin phosphorelay controls rice grain size显示文摘Plant hormone cytokinin signals through histidine-aspartic acid(H-D)phosphorelay to regulate plant growth and development.While it is well known that the phosphorelay involves histidine kinases,histidine phosphotransfer proteins(HPs),and response regulators(RRs),how this process is regulated by external components remains unknown.Here we demonstrate that protein phosphatase with kelch-like domains(PPKL1),known as a signaling component of steroid hormone brassinosteroid,is actually a cryptic inhibitor of cytokinin phosphorelay in rice(Oryza sativa).Mutation at a specific amino acid D364 of PPKL1 activates cytokinin response and thus enlarges grain size in a semi-dominant mutant named s48.Overexpression of PPKL1 containing D364,either with the deletion of the phosphatase domain or not,rescues the s48 mutant phenotype.PPKL1 interacts with OsAHP2,one of authentic HPs,and D364 resides in a region resembling the receiver domain of RRs.Accordingly,PPKL1 can utilize D364 to suppress OsAHP2-to-RR phosphorelay,whereas mutation of D364 abolishes the effect.This function of PPKL1 is independent of the phosphatase domain that is required for brassinosteroid signaling.Importantly,editing of the D364-residential region produces a diversity of semi-dominant mutations associated with variously increased grain sizes.Further screening of the edited plants enables the identification of two genotypes that confer significantly improved grain yield.Collectively,our study uncovers a noncanonical cytokinin signaling suppressor and provides a robust tool for seed rational design. | Dapu Liu He Zhao Yunhua Xiao Guoxia Zhang Shouyun Cao Wenchao Yin Yangwen Qian Yanhai Yin Jinsong Zhang Shouyi Chen Chengcai Chu Hongning Tong | 2022 | Molecular Plant2022，15，2： | 3 |
| 11 | Multi-objective Collaborative Optimization for the Lightweight Design of an Electric Bus Body Frame显示文摘To analyze the rollover safety,finite element models were established for the electric bus body frame,rollover simulation platform,living space,and bus rollover.The strength and stiffness of the body frame were calculated under four typical work-ing conditions considering the main low-order elastic modal characteristics.The results indicate that the initial body frame of the electric bus satisfies the required structural strength,stiffness,modes,and rollover safety,and it has great potential for lightweight design.Sensitivity and structural contribution analyses were performed to determine the design variables for lightweight optimization of the body frame,and a mathematical model was established for multi-objective collaborative optimization design of the electric bus.Then,the radial basis function neural network was used to approximate the optimiza-tion model.Besides,the accuracy of the approximate model was verified,and the non-dominated sorting genetic algorithm II was employed to determine solutions for the lightweight optimization.Compared with the initial model,the mass of the optimized model is reduced by 240 kg(9.0%)without any changes in the materials of the body frame. | Dengfeng Wang Chong Xie Yuchang Liu Wenchao Xu Qi Chen | 2020 | Automotive Innovation2020，3，3： | 2 |
| 12 | Proteome identification of binding-partners interacting with cell polarity protein Par3 in Jurkat cells显示文摘evolutionarily 保存的房间极性蛋白质 Par3,像支架的 PDZreontaining 蛋白质,在上皮的房间极性的建立和维护起一个关键作用。尽管在在上皮的房间建立房间极性的 Par3 的角色强烈地被探索了,在造血的房间的 Par3 的功能留下逃犯。处理这个问题,我们产生了 Par3 PDZ 领域的 GST 熔化蛋白质。由把 GST-pull-down 途径与液体层析双人脚踏车团 spectrometry 相结合,我们在 Jurkat 房间(一根 T 房间线) 识别了 Par3 的 PDZ 领域的 10 潜在的新奇有约束力的蛋白质。有三蛋白质的 Par3 的相互作用—原子运输蛋白质 importin-α4 和 proteasome 使活跃之物 PA28β 和 PA28γ—被证实在 vitro 绑定试金, co-immunoprecipitation 试金和免疫荧光显微镜学使用。我们的结果有潜力揭开在血房间的房间极性蛋白质 Par3 的新奇功能。 | Ying Zhou Longhou Fang Dan Du Wenchao Zhou Xiujing Feng Jiwu Chen Zhe Zhang Zhengjun Chen | 2008 | Acta Biochimica et Biophysica Sinica2008，40，8： | 2 |
| 13 | Co-editing PINK1 and DJ-1 Genes Via Adeno-Associated Virus-Delivered CRISPR/Cas9 System in Adult Monkey Brain Elicits Classical Parkinsonian Phenotype显示文摘Whether direct manipulation of Parkinson’s disease(PD)risk genes in the adult monkey brain can elicit a Parkinsonian phenotype remains an unsolved issue.Here,we used an adeno-associated virus serotype 9(AAV9)-delivered CRISPR/Cas9 system to directly co-edit PINK1 and DJ-1 genes in the substantia nigras(SNs)of two monkey groups:an old group and a middle-aged group.After the operation,the old group exhibited all the classic PD symptoms,including bradykinesia,tremor,and postural instability,accompanied by key pathological hallmarks of PD,such as severe nigral dopaminergic neuron loss(>64%)and evidentα-synuclein pathology in the gene-edited SN.In contrast,the phenotype of their middle-aged counterparts,which also showed clear PD symptoms and pathological hallmarks,were less severe.In addition to the higher final total PD scores and more severe pathological changes,the old group were also more susceptible to gene editing by showing a faster process of PD progression.These results suggested that both genetic and aging factors played important roles in the development of PD in the monkeys.Taken together,this system can effectively develop a large number of genetically-edited PD monkeys in a short time(6–10 months),and thus provides a practical transgenic monkey model for future PD studies. | Hao Li Shihao Wu Xia Ma Xiao Li Tianlin Cheng Zhifang Chen Jing Wu Longbao Lv Ling Li Liqi Xu Wenchao Wang Yingzhou Hu Haisong Jiang Yong Yin Zilong Qiu Xintian Hu | 2021 | Neuroscience Bulletin2021，37，9： | 2 |
| 14 | FGF-receptor substrate 2 functions as a molecular sensor ntegrating external regulatory signals into the FGF pathway显示文摘(FRS2 ) 成纤维细胞生长因素(FGF ) 受体底层 2 是在 FGF 小径发信号的主要调停人。最近的研究在 FRS2 显示出那激活 mitogen 的蛋白质 kinase (MAPK ) phosphorylates 丝氨酸和 threonine 残余,否定地影响 FRS2 的导致 FGF 的酷氨酸 phosphorylation (PY ) 。几种刺激能导致 FRS2 的 serine/threonine phosphorylation (PS/T ) ,显示 FRS2 可能为学习在表明小径的生长因素之间的串音是有用的。这里,我们报导 FRS2 的导致 FGF 的 PY 能被 EGF 合作刺激在 PC12 房间稀释;这禁止的效果能被 U0126 完全颠倒, MEK 的一个禁止者。我们进一步在 FRS2 识别了 ERK1/2-binding 主题并且在 FGF 或 EGF 刺激之上产生了 FRS2-3KL,变异的缺乏 MAPK 绑定和磅。不同野类型(WT ) FRS2, FRS2-3KL 的导致 FGF 的 PY 不能被 EGF 合作刺激,和更展出的 FRS2-3KL-expressing PC12 房间禁止响应 FGF 处理比 FRS2-WT-expressing 房间区分潜力。这些结果建议 FRS2 的 PS/T 由 FRS2-MAPK 否定规章的循环调停了可以作为从另外的小径把否定规章的信号集成到产生 FGFR 的信号 transduction 的一个分子的开关工作。 | Wenchao Zhou Xiujing Feng Yingjie Wu Johannes Benge Zhe Zhang Zhengjun Chen | 2009 | Cell Research2009，19，10： | 2 |
| 15 | Rosuvastatin May Reduce the Incidence of Cardiovascular Events in Patients with Acute Coronary Syndromes Receiving Percutaneous Coronary Intervention by Suppressing miR‐155/ SHIP ‐1 Signaling Pathway显示文摘 | Wenchao Xie Ping Li Zhengdong Wang Jian Chen Zhihai Lin Xiangwen Liang Yingxi Mo | 2014 | Cardiovasc Ther2014，，6： | 1 |
| 16 | Ionic liquid-aqueous solution ultrasonic-assisted extraction of three kinds of alkaloids from Phellodendron amurense Rupr and optimize conditions use response surface显示文摘 | Qingyong Li Wenchao Wang Yuhui Liu Binbin Chen | 2014 | Ultrasonics - Sonochemistry2014，，： | 1 |
| 17 | Effects of SNPs and alternative splicing within HGF gene on its expression patterns in Qinchuan cattle显示文摘Background: Identification of genetic variants, including SNPs(Single Nucleotide Polymorphisms), CNVs(Copy Number Variations) and alternative splicing, within functional genes has received increasing attention in animal science research. HGF(Hepatocyte Growth Factor) is a very important growth factor that works as a mitogen or a morphogen during tissue growth, development and regeneration. However, to date, the functions of genetic variants within the bovine HGF gene, particularly their effects on m RNA expression, have not been determined well.Results: The present study aimed to perform association analysis between genetic variants and m RNA expression for the bovine HGF gene in Qinchuan cattle using various strategies, including PCR-RFLP(Restriction Fragment Length Polymorphism), q PCR(Quantitative Real-time quantitative PCR), TA cloning, DNA sequencing and bioinformatics analysis. A total of five SNPs were identified and only SV1 locus significantly affected HGF m RNA expression in fetal skeletal muscle(P < 0.05). Heterozygous genotype individuals showed significantly higher HGF expression(P < 0.05), which was significantly greater in the 'CTCCAGGGTT' combined genotype than that in the'CCCCGGGGTT' combined genotype(P < 0.05). In addition, two alternative splicing variations, HGF-W and HGF-M,were identified, which resulted from alternative 3′ splice sites of exon 5, and HGF-W showed higher m RNA levels than HGF-M in all tissues.Conclusion: In summary, genetic variations within the HGF gene affected m RNA expression. These findings provide new insight into the molecular characteristics and functions of bovine HGF. | Hanfang Cai Yang Zhou Wenchao Jia Bowen Zhang Xianyong Lan Chuzhao Lei Xintang Fang Hong Chen | 2016 | Journal of Animal Science and Biotechnology2016，7，2： | 1 |
| 18 | Synthesis,crystal structures,electrochemical and spectroscopic properties of ruthenium(Ⅱ) complexes containing diamino-1,3,5-triazine derivatives显示文摘Three Ru(Ⅱ) complexes [Ru(bpy)2(1-IQTNH)](ClO4)2 (1), [Ru(bpy)2(2-QTNH)](ClO4)2 (2) and [Ru(bpy)2(3-IQTNH)](ClO4)2 (3) (bpy = 2,2′-bipyridine, 1-IQTNH = 6-(isoquinolin-1-yl)-1,3,5-triazine-2,4-diamine, 2-QTNH = 6-(quinolin-2-yl)-1,3,5-triazine-2,4-diamine, 3-IQTNH = 6-(isoquinolin-3-yl)-1,3,5-triazine-2,4-diamine) have been synthesized and characterized by elemental analysis, 1H NMR spectroscopy, electrospray ionization mass spectrometry and X-ray crystallography. The electrochemical and spectroscopic properties of the complexes differ from those of [Ru(bpy)3]2+ owing to the structural differences between the ligands and their complexes. | CHEN Yu, XU WenChao, KOU JunFeng, WEI XuHui, YU BoLe, CHAO Hui & JI LiangNian MOE Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry and Chemical Engineering, Sun Yat-Sen University, Guangzhou 510275, China | 2010 | Science China Chemistry2010，53，10： | 1 |
| 19 | Improved Calculation of Turbulence Parameters Based on Six Tropical Cyclone Cases:Implication to Wind Turbine Design in Typhoon-Prone Areas显示文摘In view of the absence or insufficiency of tropical cyclone(TC) turbulence parameters in current design standards of wind turbines, in this paper, TC turbulence parameter models with roughness length involved are developed based on six landfall TCs observed from meteorological towers located on various underlying surfaces, so as to provide references for the wind turbine design under TC conditions. Firstly, the roughness length values are examined in order to reduce the effect on turbulence parameters of the various underlying surfaces. On this basis, the reference turbulence intensity is normalized by the roughness length. The related turbulence parameters are parameterized, including the turbulence standard deviation and the turbulence spectrum;and the turbulence parameters available under TC conditions for turbulence turbine design are presented finally. Comparisons of the wind parameter models presented in this paper with those used in current turbine design standards suggest that the former can represent TC characteristics more accurately. In order to withstand TCs, we suggest that the turbulence parameter models recommended in this paper be included in future wind turbine design standards under TC conditions. | Binglan WANG Zhiqiang HE Lili SONG Wenchao CHEN | 2019 | Journal of Meteorological Research2019，33，5： | 1 |
| 20 | Value of metabolic parameters in distinguishing primary mediastinal lymphomas from thymic epithelial tumors显示文摘Objective:A high rate of unnecessary thymectomies has been reported.This study aimed to distinguish primary mediastinal lymphomas(PMLs)from thymic epithelial tumors(TETs)by evaluating volumetric and metabolic parameters with l8F-FDG PET/CT.Methods:A total of 136 patients who were pathologically diagnosed with TETs or PMLs were enrolled,and 18F-FDG PET/CT was performed before therapy.Volumetric parameters,including the mean SUV(SUVmean),metabolic tumor volume(MTV),total lesion glycolysis(TLG),and SUVmax,were determined and compared between the 2 subtypes.The diagnostic performance of these parameters was evaluated with receiver operating characteristic(ROC)curve analysis.Results:All parameters significantly differed between patients with PMLs and TETs.Patients with lymphomas were younger and had higher SUVmean,SUVmax,TLG,and MTV values than patients with TETs.The MTV and TLG values had similar diagnostic performance.ROC analysis indicated that the areas under the curves of the SUVmean and SUVmax values performed similarly(approximately 0.76)in differentiating patients with PMLs from TETs,and both values were better than the MTV and TLG values.When age was included with the SUVmax in differentiating TETs from PMLs,the AUC was 0.91,and the sensitivity and specificity increased to 80%and 93%,respectively.Conclusions:The SUVmax and volumetric parameters of 18F-FDG PET/CT can be used to distinguish patients with PMLs versus TETs,and thus may aid in preventing unnecessary thymectomies or other invasive operations. | Lei Zhu Xiaofeng Li Jian Wang Qiang Fu Jianjing Liu Wenchao Ma Wengui Xu Wei Chen | 2020 | Cancer Biology & Medicine2020，17，2： | 1 |
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