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| 1 | Human fetal mesenchymal stem cells differentiate into brown and white adipocytes: a role for ERRα in human UCP1 expression显示文摘我们调查了胎儿的间充质的干细胞(fMSCs ) 的能力区分进棕色、白的 adipocytes 并且比较了很多标记基因和关键规章的因素的表示。我们证明关键 adipocyte 管理者和标记的表示在另外的人、鼠科的 adipocyte 模型在区别期间类似于那,包括 PPAR 纬 2 和 FABP4 的正式就职。尤其是,我们发现 preadipocyte 标记, Pref-1,当这个过程继续,显著地在区别然后衰落早被导致,当他们承诺 adipogenic 系,建议 fMSCs 首先获得 preadipocyte 特征,在他们进成熟 adipocytes 的区别以前。在 adipogenic 正式就职以后,某干细胞孤立区分了进类似于棕色的 adipocytes 和其它进白 adipocytes 的房间。一个的详细调查孤立证明新奇棕色的胖决定的因素 PRDM16 在区别前后两个都被表示。重要地,展出的这些房间提高了基础 UCP-1 表示,它依赖于孤儿的活动原子受体犯错伪,加亮一个新奇角色为犯错在人的棕色的脂肪的伪。因此 fMSCs 代表一在 vitro 有用为人的 adipogenesis 当模特儿,并且提供机会在对 adipocyte 系的承诺以前学习阶段。他们也提供无价的卓见进人的棕色的脂肪的特征。 | Daniel L Morganstein Pensee Wu Meritxell R Mane Nick M Fisk Roger White Malcolm G Parker | 2010 | Cell Research2010，20，4： | 5 |
| 2 | 持续气道正压通气在预防阻塞性睡眠呼吸暂停患者心血管事件中的作用显示文摘阻塞性睡眠呼吸暂停(obstructive sleep apnea,OSA)导致阵发性低氧血症,夜间交感神经系统激活,血压、氧化应激和炎症指标的升高以及高凝血症。较大的胸内负压波动也会给心脏和大血管施加机械应力。基于人群和睡眠诊所的队列研究显示,OSA与心脑血管事件,特别是脑卒中相关。 | McEvoy RD Antic NA Heeley E Luo Y Ou Q Zhang X Mediano O Chen R Drager LF Liu Z Chen G Du B McArdle N Mukherjee S Tripathi M Billot L Li Q Lorenzi-Filho G Barbe F Redline S Wang J Arima H Neal B White DP Grunstein RR Zhong N Anderson CS 练桂丽 叶鹏 | 2016 | 中华高血压杂志2016，24，11： | 4 |
| 3 | 卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景
缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。 | Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 | 2017 | 国际脑血管病杂志2017，25，5： | 2 |
| 4 | Sweet cherry fruit distribution and leaf populations: modeling canopy dynamics and management strategies显示文摘 | Lang G A Olmstead J W Whiting M D | 2004 | Aeta Hortic2004，636，： | 1 |
| 5 | Urinary cortisol, urea nitrogen excretion, and winter survival in mule deer fawns 显示文摘 | Saltz D White G C Bartmann R M | 1992 | J Wildl Manage1992，56，： | 1 |
| 6 | Measuring fractional cover and leaf area index in arid ecosystems: digital camera, radiation transmittance, and laser altimetry methods显示文摘 | White M A Asner G P Nemani R R | 2000 | Remote Sensing of Environment2000，74，1： | 1 |
| 7 | Propofol in paediatrie 显示文摘 | Morton N Johnson G White M | 1992 | Anaesthesia1992，2，1： | 1 |
| 8 | Novel robotic da Vinci instruments for lap aroendoscopic single-site surgery显示文摘 | Haber G P White M A Autorino R Escobar P F Kroh M D Chalikonda S | 2010 | Urology2010，76，： | 1 |
| 9 | Metabolic engineering for the microbial production of 1,3-propanediol 显示文摘 | NAKAMURA C E WHITED G M | 2003 | Current Opinion in Biotechnolo- gy2003，14，5： | 1 |
| 10 | Effect of transportation and handing of calves upon blood serum compo-sition 显示文摘 | Crookshank H R Elissalde M H White R G | 1979 | Journal of Animal Science1979，48，3： | 1 |
| 11 | Human parathyroid hormone 1-34 reverses bone loss in ovariectomized mice显示文摘 | Alexander JM Bab I Fish S Muller R Uchiyama T Gronowicz G Nahounou M Zhao Q White DW Chorev M Gazit D Rosenblatt M | | 0，，： | 1 |
| 12 | Differential patterns of methylation of the IFN-gamma promoter at CpG and non-CpG sites underlie differences in IFN- gamma gene expression between human neonatal and adults CD45RO-T cells显示文摘 | White G P Watt P M Holt B J | 2002 | The Journal of Immunolo- gy2002，168，6： | 1 |
| 13 | Metabolic engineering for the microbial production of 1,3-propanedio 显示文摘 | Nakamura C E Whited G M | 2003 | Current Opinion in Biotechnology2003，14，： | 1 |
| 14 | The neural circuit for touch sensitivity in Caenorhabditis elegans显示文摘 | CHALFIE M SULSTON J E WHITE J G | 1985 | J Neurosci1985，5，4： | 1 |
| 15 | Super acidic ionic liquids for arene car- bonylation derived from dialkylimidazolium chlorides and MCI3 (M = AI, Ga, or In ) 显示文摘 | Angueira E J White M G | 2007 | Journal of Molecular Catalysis A: Chemical2007，277，12： | 1 |
| 16 | Internal Finance and Firm Investment显示文摘 | Hubbard R G Kashyap A K Whited T M | 1995 | Journal of Money Credit and Banking1995，27，3： | 1 |
| 17 | Single-port urological surgery:single-centor experience with the first 100 cases显示文摘 | White W M Haber G P Goel R K | 2009 | Urology2009，74，4： | 1 |
| 18 | Fatty acid metabolism by the porcine placenta显示文摘 | Ramsay T G Karousis J White M E | 1991 | J Anim Sci1991，69，： | 1 |
| 19 | Enhanced Coagulation:Its Effect on NOM Removal and Chemical Costs显示文摘 | Crozes G White P Marshall M | 1995 | Amer Water Works Assoc1995，87，1： | 1 |
| 20 | Stress-cracking in white corn as affected by drying temperature and cooling rate显示文摘 | G M White | 1972 | Transaction of ASAE1972，，3： | 1 |
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